Zu "K04291" wurden 18 Artikel gefunden!
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H2L5186303
Artikelnummer: Cay14663-1
H2L5186303 is a selective lysophosphatidic acid 2 (LPA2) receptor antagonist (IC50 = 9 nM in a LPA-elicited calcium mobilization assay). It inhibits LPA1 and LPA3 at much higher concentrations (IC50s = 27,354 and 4,504 nM, respectively).Formal Name:...
| Schlagworte: | (Z,Z)-4,4'-[1,3-phenylenebis(oxy-4,1-phenyleneimino)]bis[4-oxo-2-butenoic acid |
| Anwendung: | LPAR2 antagonist |
| CAS | 139262-76-3 |
| MW: | 488.5 D |
ab 48,00 €
1-Linoleoyl-2-hydroxy-sn-glycero-3-PA (sodium salt)
Artikelnummer: Cay38309-1
1-Linoleoyl-2-hydroxy-sn-glycero-3-PA (sodium salt) (1-linoleoyl LPA) is an agonist of the LPA2 receptor and a glycerophospholipid containing linoleic acid (Cay-90150, Cay-90150.1, Cay-21909) at the sn-1 position. It is the most abundant LPA in mouse and human plasma. 1-Linoleoyl LPA selectively increases...
| Schlagworte: | PA(18:2(9Z,12Z)/0:0), 18:2 Lyso PA, 1-Linoleoyl LPA, 1-Linoleoyl-2-hydroxy-sn-glycero-3-PA,... |
| Anwendung: | LPA2 receptor agonist, glycerophospholipid |
| CAS | 72777-86-7 |
| MW: | 434.5 D |
ab 90,00 €
DBIBB
Artikelnummer: Cay17529-5
The lysophosphatidic acid (LPA) receptor LPA2 is a G protein-coupled receptor that has roles in protecting against radiation-induced cell death. DBIBB is a non-lipid agonist of LPA2 (EC50 = 0.10 µM) that is without effect at other LPA receptor subtypes. It protects rat intestinal crypt epithelium-like IEC-6 cells...
| Schlagworte: | 2-[[[4-(1,3-dioxo-1H-benz[de]isoquinolin-2(3H)-yl)butyl]amino]sulfonyl]-benzoic acid |
| Anwendung: | LPA2 agonist |
| CAS | 1569309-92-7 |
| MW: | 452.5 D |
ab 77,00 €
1-Arachidonoyl-2-hydroxy-sn-glycero-3-PA (ammonium salt)
Artikelnummer: Cay10019-1
1-Arachidonoyl-2-hydroxy-sn-glycero-3-PA is a phospholipid containing arachidonic acid at the sn-1 position. It has been found in rat brain as 37% of the arachidonic acid-containing lysophosphatidic acid (LPA) species and is a precursor to 1-arachidonoyl glycerol (1-AG, Cay-62150)....
| Schlagworte: | 1-Arachidonoyl LPA, 1-Arachidonoyl-sn-glycero-3-phosphate, 1-Eicosatetraenoyl-sn-glycero-3-PA, 20:4 Lyso PA, LPA(20:4),... |
| CAS | 799268-65-8 |
| MW: | 475.6 D |
ab 64,00 €
LPA2 Antagonist 1
Artikelnummer: Cay22051-1
LPA2 antagonist 1 is an antagonist of lysophosphatidic acid receptor 2 (LPA2, IC50 = 17 nM). It is selective for LPA2 over LPA1 and LPA3 (IC50s = >50 µM). LPA2 antagonist 1 inhibits HGF-induced phosphorylation of ERK and proliferation of HCT116 colon cancer cells in a concentration-dependent manner.Formal Name:...
| Schlagworte: | LPA2-IN-1, N-[(1S)-2-[4-[(3,4-dichlorophenyl)sulfonyl]-1-piperazinyl]-1-methylethyl]-7-methyl-thieno[3,2-d]pyrimidin-4-amine |
| Anwendung: | LPAR2 antagonist |
| CAS | 1017606-66-4 |
| MW: | 500.5 D |
ab 316,00 €
Anti-LPAR2
Artikelnummer: E-AB-12919.120
This gene encodes a member of family I of the G protein-coupled receptors, as well as the EDG family of proteins. This protein functions as a lysophosphatidic acid (LPA) receptor and contributes to Ca2+ mobilization, a critical cellular response to LPA in cells, through association with Gi and Gq proteins. An...
| Schlagworte: | Anti-EDG4, Anti-LPA-2, Anti-LPAR2, Anti-LPA receptor 2, Anti-Lysophosphatidic acid receptor 2, Anti-Lysophosphatidic acid... |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 71,00 €
GRI-977143
Artikelnummer: Cay21900-1
GRI-977143 is an agonist of G protein-coupled lysophosphatidic acid receptor 2 (LPA2) with an EC50 value of 3.3 µM in LPA2-transfected RH7777 cells. It is selective for LPA2, having no activity at LPA1, LPA3, LPA4, and LPA5 at concentrations up to 10 µM. GRI-977143 increases growth and reduces caspase-3 and -7...
| Schlagworte: | 2-[[3-(1,3-dioxo-1H-benz[de]isoquinolin-2(3H)-yl)propyl]thio]-benzoic acid |
| Anwendung: | LPA2 receptor agonist |
| CAS | 325850-81-5 |
| MW: | 391.4 D |
ab 48,00 €
Anti-LPAR2
Artikelnummer: E-AB-65121.120
This gene encodes a member of family I of the G protein-coupled receptors, as well as the EDG family of proteins. This protein functions as a lysophosphatidic acid (LPA) receptor and contributes to Ca2+ mobilization, a critical cellular response to LPA in cells, through association with Gi and Gq proteins. An...
| Schlagworte: | Anti-EDG4, Anti-LPA-2, Anti-LPAR2, Anti-LPA receptor 2, Anti-Lysophosphatidic acid receptor 2, Anti-Lysophosphatidic acid... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 198,00 €
Anti-LPAR2 / EDG4
Artikelnummer: ARG54850.100
Protein function: Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Seems to be coupled to the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins. Plays a key role in phospholipase C-beta (PLC-beta) signaling pathway. Stimulates phospholipase C (PLC) activity in a...
| Schlagworte: | Anti-EDG4, Anti-LPA-2, Anti-LPAR2, Anti-LPA receptor 2, Anti-Lysophosphatidic acid receptor 2, Anti-Lysophosphatidic acid... |
| Anwendung: | IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
624,00 €
Anti-LPAR2
Artikelnummer: G-CAB14819.100
WB 1:500 - 1:2000. Protein function: Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Seems to be coupled to the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins. Plays a key role in phospholipase C-beta (PLC-beta) signaling pathway. Stimulates phospholipase C...
| Schlagworte: | Anti-EDG4, Anti-LPA-2, Anti-LPAR2, Anti-LPA receptor 2, Anti-Lysophosphatidic acid receptor 2, Anti-Lysophosphatidic acid... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 352,00 €
Anti-LPAR2
Artikelnummer: ATA-HPA019616.100
Protein function: Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Seems to be coupled to the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins. Plays a key role in phospholipase C-beta (PLC-beta) signaling pathway. Stimulates phospholipase C (PLC) activity in a...
| Schlagworte: | Anti-EDG4, Anti-LPAR2, Anti-LPA-2, Anti-LPA receptor 2, Anti-Lysophosphatidic acid receptor 2, Anti-Lysophosphatidic acid... |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 335,00 €
EDG4, Human, Real Time PCR Primer Set
Artikelnummer: VHPS-2844
Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
| Schlagworte: | EDG4, LPAR2, LPA-2, LPA receptor 2, Lysophosphatidic acid receptor 2, Lysophosphatidic acid receptor Edg-4 |
| Anwendung: | RNA quantification |
43,00 €