Zu "K04290" wurden 40 Artikel gefunden!
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TY 52156
Artikelnummer: Cay19119-5
TY 52156 is a selective sphingosine-1-phosphate receptor 3 (SIP3) antagonist (Ki = 110 nM). It preferentially inhibits the S1P-induced increase in intracellular calcium in Chinese hamster ovary cells expressing S1P3 over cell expressing S1P1, S1P2, or S1P4. TY 52156 has been shown to suppress FTY720-induced S1P3...
| Schlagworte: | N-(4-chlorophenyl)-3,3-dimethyl-2-oxobutanimidic acid, 2-(4-chlorophenyl)hydrazide |
| Anwendung: | S1PR3 antagonist |
| CAS | 934369-14-9 |
| MW: | 364.3 D |
ab 49,00 €
CYM 5541
Artikelnummer: Cay15190-5
The sphingosine 1-phosphate (S1P) receptor S1P3 has roles in vasodilation, epithelial barrier function, cardioprotection, fibrosis, immunity, and inflammation. CYM 5541 is a selective, allosteric agonist of S1P3 (EC50 = 72-132 nM). It less effectively activates S1P1 (EC50 = 28-38 µM) and is ineffective at S1P2,...
| Schlagworte: | CID-17253208, ML-249, N,N-dicyclohexyl-5-cyclopropyl-3-isoxazolecarboxamide |
| Anwendung: | Allosteric agonist of S1P3 |
| CAS | 945128-26-7 |
| MW: | 316.4 D |
ab 93,00 €
Anti-S1P3
Artikelnummer: Cay10006373-1
Sphingosine-1-phosphate (S1P) exerts its activity by binding to five distinct G-protein-coupled receptors, S1P1/EDG-1, S1P2/EDG-5, S1P3/EDG-3, S1P4/EDG-6, and S1P5/EDG-8. S1P3 couples to Gi/o-ERK, Gq-PLC, and G12/13-Rho axes to mediate S1P-induced cell proliferation, survival, migration, and related signaling...
| Schlagworte: | Anti-EDG3, Anti-S1P3, Anti-S1P3, Anti-S1PR3, Anti-S1P receptor 3, Anti-S1P receptor 3, Anti-S1P receptor Edg-3, Anti-S1P... |
| Anwendung: | ICC, WB |
| Wirt: | Rabbit |
468,00 €
TY-52156
Artikelnummer: TGM-T17183-200mg
Description: TY-52156 is an effective and selective S1P3 receptor antagonist (Ki: 110 nM). Target: LPL Receptor, S1P Receptor. Smiles: CC(C)(C)C(=O)C(\NNc1ccc(Cl)cc1)=N\c1ccc(Cl)cc1
| Anwendung: | S1PR3 antagonist |
| CAS | 934369-14-9 |
| MW: | 364.27 D |
ab 33,00 €
VPC 23019
Artikelnummer: Cay13240-500
Sphingosine-1-phosphate (S1P, Cay-62570) is a bioactive lipid that exhibits a broad spectrum of biological activities including cell proliferation, survival, migration, cytoskeletal organization, and morphogenesis. It exerts its activity by binding to five distinct G protein-coupled receptors, S1P1/EDG-1,...
| Schlagworte: | (R)-2-amino-3-((3-octylphenyl)amino)-3-oxopropyl dihydrogen phosphate |
| Anwendung: | Competitive S1P1 / S1P3 receptor antagonist |
| CAS | 449173-19-7 |
| MW: | 372.4 D |
ab 60,00 €
Lipid-based Drug Delivery-Tools
Sphingosine-1-phosphate (d16:1)
Artikelnummer: Cay9002921-5
C16 Sphingosine-1-phosphate (C16 S1P) is a derivative of sphingosine-1-phosphate (S1P, Cay-62570) that binds to S1P1/EDG-1, S1P3/EDG-3, and S1P2/EDG-5 receptors with affinities of 115%, 83%, and 103%, respectively, relative to S1P in CHO cells. C16 S1P was increased in postmortem primary open angle glaucoma...
| Schlagworte: | C16 S1P, C16 Sphingosine-1-phosphate, S1P (d16:1), 2S-amino-1-(dihydrogen phosphate), 4E-hexadecene-1,3R-diol |
| Anwendung: | S1PR1/S1PR2/S1PR3 ligand |
| CAS | 709026-60-8 |
| MW: | 351.4 D |
ab 305,00 €
Anti-S1PR3
Artikelnummer: CSB-PA007902.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-EDG3, Anti-S1P3, Anti-S1PR3, Anti-S1P receptor 3, Anti-S1P receptor Edg-3, Anti-Sphingosine 1-phosphate receptor 3,... |
| Anwendung: | ELISA, WB, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 126,00 €
Human S1P3 / EDG5 ELISA Kit
Artikelnummer: G-HUFI00627.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
698,00 €
Mouse S1P3 / EDG5 ELISA Kit
Artikelnummer: G-MOFI00222.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
698,00 €
Anti-EDG3
Artikelnummer: NSJ-R36075-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Endothelial differentiation gene-3, sphingosine-1-phosphate receptor 3 (S1PR3) Protein function: Receptor for the lysosphingolipid sphingosine 1- phosphate (S1P). S1P is a bioactive...
| Schlagworte: | Anti-EDG3, Anti-S1P3, Anti-S1PR3, Anti-S1P receptor 3, Anti-S1P receptor Edg-3, Anti-Sphingosine 1-phosphate receptor 3,... |
| Anwendung: | IHC, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
836,00 €
Anti-S1PR3
Artikelnummer: E-AB-12921.120
This gene encodes a member of the EDG family of receptors, which are G protein-coupled receptors. This protein has been identified as a functional receptor for sphingosine 1-phosphate and likely contributes to the regulation of angiogenesis and vascular endothelial cell function. Receptor for the lysosphingolipid...
| Schlagworte: | Anti-S1P3, Anti-EDG3, Anti-S1PR3, Anti-S1P receptor 3, Anti-S1P receptor Edg-3, Anti-Sphingosine 1-phosphate receptor 3,... |
| Anwendung: | WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 89,00 €
D-erythro/L-threo Lysosphingomyelin (d18:1)
Artikelnummer: Cay31557-5
Lysosphingomyelin is an endogenous bioactive sphingolipid and a constituent of lipoproteins. It is produced by the removal of the acyl group from sphingomyelin by a deacylase and acts as a precursor in the biosynthesis of sphingosine-1-phosphate (S1P, Cay-62570). D-erythro Lysosphingomyelin is an agonist of the S1P...
| Schlagworte: | D-erythro/L-threo Lyso SM(18:1), D-erythro/L-threo Sphingosine-1-Phosphocholine (d18:1),... |
| Anwendung: | Bioactive sphingolipid mixture |
| CAS | 82970-80-7 |
| MW: | 464.6 D |
ab 289,00 €