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Zu "K04284" wurden 29 Artikel gefunden!
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Artikelnummer: Cay40142-1
PF-05190457 is an inverse agonist of the growth hormone secretagogue receptor (GHS-R), which is also known as the ghrelin receptor. It selectively binds to GHS-R (Ki = 4.37 nM) over M2 muscarinic acetylcholine receptors (mAChRs, Ki = 1,950 nM) and the serotonin (5-HT) receptor subtype 5-HT2B (IC50 = 3,700 nM)....
Schlagworte: | 1-[2-[(1R)-2,3-dihydro-5-(6-methyl-4-pyrimidinyl)-1H-inden-1-yl]-2,7-diazaspiro[3.5]non-7-yl]-2-(2-methylimidazo[2,1-b]thi... |
Anwendung: | GHS-R inverse agonist |
CAS | 1334782-79-4 |
MW: | 512.7 D |
ab 47,00 €
Artikelnummer: ELK-ELK4217.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human GHSR. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human GHSR. Next,...
Schlagworte: | GHRP, GHSR, GHS-R, Ghrelin receptor, GH-releasing peptide receptor, Growth hormone secretagogue receptor type 1 |
Anwendung: | ELISA |
Spezies-Reaktivität: | human |
ab 365,00 €
Artikelnummer: ELK-EA292.100
Receptor for ghrelin, coupled to G-alpha-11 proteins. Stimulates growth hormone secretion. Binds also other growth hormone releasing peptides (GHRP). Protein function: Receptor for ghrelin, coupled to G-alpha-11 proteins. Stimulates growth hormone secretion. Binds also other growth hormone releasing peptides (GHRP)...
Schlagworte: | Anti-GHRP, Anti-GHSR, Anti-GHS-R, Anti-Ghrelin receptor, Anti-GH-releasing peptide receptor, Anti-Growth hormone... |
Anwendung: | WB, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
283,00 €
Artikelnummer: Cay36586-1
Alexamorelin is a synthetic heptapeptide agonist of the growth hormone secretagogue receptor (GHS-R).Formal Name: L-alanyl-L-histidyl-2-methyl-D-tryptophyl-L-alanyl-L-tryptophyl-D-phenylalanyl-L-lysinamide, trifluoroacetate salt. Synonyms: Ala-His-D-2-Methyl-Trp-Ala-Trp-D-Phe-Lys-NH2. Molecular Formula: C50H63N13O7...
Schlagworte: | Ala-His-D-2-Methyl-Trp-Ala-Trp-D-Phe-Lys-NH2,... |
Anwendung: | Synthetic heptapeptide GHS-R agonist |
MW: | 958.1 D |
ab 212,00 €
Artikelnummer: Cay30716-1
Hexarelin is a synthetic hexapeptide agonist of the growth hormone secretagogue receptor (GHS-R). It selectively binds to GHS-R over CD36 (IC50s = 15.9 and 2,080 nM, respectively). Hexarelin (300 µg/kg, s.c.) increases plasma growth hormone levels in neonatal rats. It also improves left ventricular function and...
Schlagworte: | Examorelin, H-2-Me-WAWFK, His-(D)-Mrp-Ala-Trp-(D)-Phe-Lys-NH2, His-2-Me-Trp-Ala-Trp-Phe-Lys-NH2,... |
Anwendung: | GHS-R peptide agonist |
CAS | 140703-51-1 |
MW: | 887 D |
ab 109,00 €
Artikelnummer: Cay10012699-500
Ghrelin is an endogenous ligand for the growth hormone secretagogue receptor that stimulates food intake and transduces signals to hypothalamic regulatory nuclei that control energy homeostasis. JMV3002 is a potent ghrelin receptor antagonist with an IC50 value of 1.1 nM in vitro. At 80 µg/kg, JMV3002 inhibits...
Schlagworte: | N-[(1R)-1-[4-[(2,4-dimethoxyphenyl)methyl]-5-(2-phenyylethyl)-4H-1,2,4-triazol-3-yl]-2-(1H-indol-3-yl)ethyl]-2-pyridinecar... |
Anwendung: | Ghrelin receptor antagonist |
CAS | 925239-03-8 |
MW: | 586.7 D |
ab 81,00 €
Artikelnummer: Cay27262-5
GHRP-6 is a synthetic growth hormone (GH) secretagogue and an agonist of the GH secretagogue receptor (GHS-R), which is also known as the ghrelin receptor. It inhibits binding of the GHS-R agonist MK-0677 (ibutamoren, Cay-18003) to COS-7 cell membranes expressing human GHS-R type Ia (Ki = 1.9 nM) and binding of...
Schlagworte: | Hexapeptide-2, Growth Hormone Releasing Peptide 6, HWAWFK-NH2, SKF 110679, U 75799E,... |
Anwendung: | Synthetic growth hormone, GH secretagogue receptor agonist |
CAS | 145177-42-0 |
MW: | 1053.2 D |
ab 109,00 €
Artikelnummer: Cay28811-1
GHRP-2 is an orally bioavailable synthetic growth hormone (GH) secretagogue and an agonist of the GH secretagogue receptor (GHS-R), which is also known as the ghrelin receptor. It induces GH release from primary rat pituitary cells (EC50 = 1.8 nM) and binds to human hypothalamic membranes (IC50 = 16 nM). GHRP-2...
Schlagworte: | D-Ala-3-(2-naphthalenyl)-D-Ala-L-Ala-L-Trp-D-Phe-L-lysinamide, Growth Hormone-Releasing Peptide 2, KP-102, Pralmorelin,... |
Anwendung: | GH secretagogue receptor agonist |
MW: | 932 D |
ab 130,00 €
Artikelnummer: ARG55391.100
Protein function: Receptor for ghrelin, coupled to G-alpha-11 proteins. Stimulates growth hormone secretion. Binds also other growth hormone releasing peptides (GHRP) (e.g. Met-enkephalin and GHRP-6) as well as non-peptide, low molecular weight secretagogues (e.g. L-692,429, MK-0677, adenosine). [The UniProt...
Schlagworte: | Anti-GHSR, Anti-GHRP, Anti-GHS-R, Anti-Ghrelin receptor, Anti-GH-releasing peptide receptor, Anti-Growth hormone... |
Anwendung: | IHC (paraffin), WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse |
584,00 €
Artikelnummer: G-HUFI00411.96
Anwendung: | ELISA |
Spezies-Reaktivität: | human |
641,00 €
Artikelnummer: Cay24676-10
Anamorelin is a small molecule agonist of the growth hormone (GH) secretagogue receptor 1a (GHS-R1a) and a mimetic of ghrelin (Cay-15072, Cay-24458, Ki = 0.7 nM). It induces calcium mobilization in CHO cells expressing rat GHS-R1a in a concentration-dependent manner and GH release from rat pituitary cells (EC50 =...
Schlagworte: | RC-1291,... |
Anwendung: | GHSR/ ghrelin receptor agonist |
CAS | 249921-19-5 |
MW: | 546.7 D |
ab 92,00 €
Artikelnummer: Cay18003-10
Ghrelin is an endogenous ligand for the growth hormone (GH) secretagogue receptor (GHSR). Ibutamoren is an orally-active, non-peptidic agonist of GHSR (Kd = 0.4 nM) and, as a result, is a GH secretagogue. It elevates GH in dogs after oral doses as low as 0.125 mg/kg, without significantly changing plasma levels of...
Schlagworte: | L-163,191, MK-0677,... |
Anwendung: | Growth hormone releasing factor, Ghrelin receptor agonist |
CAS | 159752-10-0 |
MW: | 624.8 D |
ab 114,00 €