Zu "K04279" wurden 41 Artikel gefunden!
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CHO-K1/PTAFR Stable Cell Line
Artikelnummer: GSC-M00262
Recombinant CHO-K1 cells stably overexpress human platelet activating factor receptor (PTAFR) on the surface and contain high levels of G protein Galphaq and Galphai to couple with the receptor in downstream signaling pathways.
| Schlagworte: | PTAFR, Platelet-activating factor receptor |
11.424,00 €
PAF C-18:1
Artikelnummer: Cay18779-5
PAF C-18:1 is a naturally occurring phospholipid produced by cells upon stimulation and plays a role in the establishment and maintenance of the inflammatory response. It is less potent than PAF C-16 (Cay-60900) and PAF C-18 (Cay-60910) in the induction of neutrophil chemotaxis, but is equipotent to PAF C-16 and PAF...
| Schlagworte: | 1-Oleoyl-2-acetyl-sn-glycero-3-phosphorylcholine, Platelet-activating Factor C-18:1,... |
| Anwendung: | Phospholipid, eosinophil migration promotor |
| CAS | 85966-90-1 |
| MW: | 549.7 D |
ab 122,00 €
CV-6209 (chloride)
Artikelnummer: Cay15955-1
CV-6209 is a potent antagonist of the platelet-activating factor (PAF) receptor, inhibiting aggregation of rabbit and human platelets induced by PAF with IC50 values of 75 and 170 nM, respectively. It has little action on platelet aggregation induced by arachidonic acid, ADP, or collagen. CV-6209 is bioavailable, as...
| Schlagworte: | 2-(2-acetyl-6-methoxy-3,9-dioxo-4,8-dioxa-2,10-diazaoctacos-1-yl)-1-ethyl-pyridinium, monochloride |
| Anwendung: | PTAFR antagonist |
| CAS | 100488-87-7 |
| MW: | 642.3 D |
ab 145,00 €
Anti-PAF Receptor (human) (11A4, Clone 21)
Artikelnummer: Cay160600-1
PAF is a potent phospholipid mediator which exerts diverse biological actions by interaction with a G protein-coupled PAF receptor. The PAF receptor has been cloned from a number of species including human, rat, and guinea pig and is characterized as a 7-transmembrane receptor which induces phosphoinositol turnover...
| Schlagworte: | Anti-PAFR, Anti-PAFr, Anti-PAFr, Anti-PTAFR, Anti-PAF-R, Anti-PAF-R, Anti-Platelet-activating factor receptor,... |
| Anwendung: | ELISA, FC, ICC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
468,00 €
Apafant
Artikelnummer: Cay14532-1
Platelet-activating factor (PAF) is a biologically active phospholipid that activates platelets, polymorphonuclear leukocytes, monocytes, and macrophages. PAF also increases vascular permeability, decreases cardiac output, induces hypotension, stimulates uterine contraction, and has been implicated in pathological...
| Schlagworte: | WEB 2086,... |
| Anwendung: | PAF receptor antagonist |
| CAS | 105219-56-5 |
| MW: | 456 D |
ab 58,00 €
Ginkgolide B
Artikelnummer: Cay14636-10
Platelet-activating factor (PAF) is an important mediator of cell proliferation, angiogenesis, inflammatory response regulation, vasodilation, superoxide formation, and platelet aggregation. These cellular effects are mediated through its specific G-protein coupled receptor, PAFR. Ginkgolide B, a terpenoid extracted...
| Schlagworte: | BN 52021, BN 52051,... |
| Anwendung: | PAFr antagonist |
| CAS | 15291-77-7 |
| MW: | 424.4 D |
ab 49,00 €
Ginkgolide C
Artikelnummer: Cay19872-10
Ginkgolide C is a flavone first extracted from G. biloba leaves with multiple reported biological functions. It has been identified as a selective platelet activating factor receptor antagonist (IC50 = 37.6 µM). Ginkgolide C has also been shown to increase lipolysis and to inhibit adipogenesis in adipocytes via the...
| Schlagworte: | 1,7-dihydroxy Ginkgolide A, BN 52022,... |
| Anwendung: | PAF receptor antagonist |
| CAS | 15291-76-6 |
| MW: | 440.4 D |
ab 49,00 €
Anti-PAF receptor
Artikelnummer: ARG56501.250
Protein function: Receptor for platelet activating factor, a chemotactic phospholipid mediator that possesses potent inflammatory, smooth- muscle contractile and hypotensive activity. Seems to mediate its action via a G protein that activates a phosphatidylinositol- calcium second messenger system. [The UniProt...
| Schlagworte: | Anti-PAFR, Anti-PAFr, Anti-PTAFR, Anti-PAF-R, Anti-Platelet-activating factor receptor |
| Anwendung: | FC, ICC, IF, IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat, swine |
707,00 €
Anti-PTAFR
Artikelnummer: E-AB-16022.120
This gene encodes a seven-transmembrane G-protein-coupled receptor for platelet-activating factor (PAF) that localizes to lipid rafts and/or caveolae in the cell membrane. PAF (1-0-alkyl-2-acetyl-sn-glycero-3-phosphorylcholine) is a phospholipid that plays a significant role in oncogenic transformation, tumor...
| Schlagworte: | Anti-PAFR, Anti-PAFr, Anti-PTAFR, Anti-PAF-R, Anti-Platelet-activating factor receptor, PTAFR Polyclonal Antibody |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 89,00 €
PAF C-16 Carboxylic Acid
Artikelnummer: Cay15392-1
PAF C-16 is a naturally occurring phospholipid produced upon stimulation through two distinct pathways known as the "remodeling" and 'de novo' pathways. It is a potent mediator of neutrophil migration and the production of reactive oxygen species and IL-6. Pathological processes involving PAF include necrotizing...
| Schlagworte: | CPAGP, Platelet-activating Factor C-16 Carboxylic Acid,... |
| Anwendung: | Phospholipid, chemical crosslinking |
| CAS | 129879-41-0 |
| MW: | 553.7 D |
ab 216,00 €
LY320135
Artikelnummer: Cay11738-5
LY320135 is a selective cannabinoid (CB) receptor 1 antagonist (Kis = 224 and >10,000 nM for CB1 and CB2, respectively, in vitro). It is selective for CB1 over alpha1- and alpha2- adrenergic, D1 and D2 dopamine, benzodiazepine, histamine H1, GABA, serotonin (5-HT), and muscarinic receptors. It reverses the...
| Schlagworte: | 4-[[6-methoxy-2-(4-methoxyphenyl)-3-benzofuranyl]carbonyl]-benzonitrile |
| Anwendung: | Cannabinoid receptor 1 (CB1) antagonist |
| CAS | 176977-56-3 |
| MW: | 383.4 D |
ab 44,00 €
Ginkgolide C
Artikelnummer: CDX-G0214-M010
White to off-white powder. Soluble in DMSO, DMF. Acetone, Ethanol, Ethyl Acetate, Dioxane and Methanol Chemical. CAS: 15291-76-6. Formula: C20H24O11. MW: 440.4. Isolated from plant source. Ginkgolide C is a flavone first extracted from G. biloba leaves with multiple reported biological functions. It has been...
| Schlagworte: | 1,7-Dihydroxy-ginkgolide A, BN 52022 |
| Anwendung: | Natural product, PAF receptor antagonist |
| CAS | 15291-76-6 |
| MW: | 440,4 D |
ab 97,00 €