Zu "K04276" wurden 26 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
Anti-GPR35 / G protein-coupled receptor 35
Artikelnummer: NSJ-FY13315
Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml. GPR35 antibody detects G protein-coupled receptor 35, a seven-transmembrane receptor encoded by the GPR35 gene on chromosome 2q37.3. GPR35 is a member of the rhodopsin-like class A GPCR family and functions as a receptor for kynurenic acid and...
| Schlagworte: | Anti-GPR35, Anti-Kynurenic acid receptor, Anti-G-protein coupled receptor 35, GPR35 Antibody / G protein-coupled receptor 35 |
| Anwendung: | WB, FC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
NPPB
Artikelnummer: Cay17292-10
NPPB is a chloride channel blocker (IC50 = 80 nM) that has also been identified as a GPR35 agonist. It has been shown to activate the GPR35-Galphai/o and GPR35-Galpha16 pathways in HEK293 cells, inducing intracellular calcium mobilization. NPPB has protonophoric activity and has been used to uncouple mitochondrial...
| Schlagworte: | HOE 144, Hoechst 144, 5-nitro-2-[(3-phenylpropyl)amino]-benzoic acid |
| Anwendung: | GPR35 agonist, chloride channel blocker |
| CAS | 107254-86-4 |
| MW: | 300.3 D |
ab 84,00 €
Lodoxamide
Artikelnummer: Cay23994-25
Lodoxamide is a potent agonist of GPR35 with an EC50 value of 1.61 nM in a beta-arrestin-2 interaction assay using CHO-K1 cells expressing the human receptor. It inhibits histamine release induced by compound 48/80 (Cay-22173), anti-IgE, or A23187 (Cay-11016) in isolated rat peritoneal mast cells (IC50s = 0.1-50 µM)...
| Schlagworte: | 2,2'-[(2-chloro-5-cyano-1,3-phenylene)diimino]bis[2-oxo-acetic acid] |
| Anwendung: | GPR35 agonist |
| CAS | 53882-12-5 |
| MW: | 311.6 D |
ab 145,00 €
CID-2745687
Artikelnummer: Cay12046-10
GPR35 is a G protein-coupled receptor that is activated by kynurenic acid and 2-acyl lysophosphatidic acids (e.g., 2-oleoyl lysophosphatidic acid). It is expressed predominantly on immune cells, the brain, and in the gastrointestinal tract. GPR35 is overexpressed in gastric cancer cells. CID-2745687 is a reversible,...
| Schlagworte: | ML-194,... |
| Anwendung: | GPR35 antagonist |
| CAS | 264233-05-8 |
| MW: | 395.4 D |
ab 139,00 €
Pamoic Acid
Artikelnummer: Cay13946-100
Pamoic acid is a potent agonist of GPR35 orphan receptors (EC50 = 79 nM in a beta-arrestin recruitment assay). It induces GPR35 translocation from the plasma membrane to the cytoplasm with an EC50 value of 22 nM. Pamoic acid also increases ERK1/2 phosphorylation in a concentration-dependent manner in U20S cells...
| Schlagworte: | Embonic Acid, NSC 30188, NSC 40132, 4,4'-methylenebis[3-hydroxy-2-naphthalenecarboxylic acid] |
| Anwendung: | Potent GPR35 agonist |
| CAS | 130-85-8 |
| MW: | 388.4 D |
ab 72,00 €
Anti-GPCR GPR35
Artikelnummer: ARG56529.250
Protein function: Acts as a receptor for kynurenic acid, an intermediate in the tryptophan metabolic pathway. The activity of this receptor is mediated by G-proteins that elicit calcium mobilization and inositol phosphate production through G(qi/o) proteins. [The UniProt Consortium]
| Schlagworte: | Anti-GPR35, Anti-KYNA receptor, Anti-Kynurenic acid receptor, Anti-G-protein coupled receptor 35 |
| Anwendung: | IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, swine |
707,00 €
Anti-GPR35
Artikelnummer: Cay10007660-1
Many G protein-coupled receptor 35 (GPR35) ligands have recently been identified including kynurenic acid (Cay-16762) and zaprinast (Cay-110010421). Multiple isoforms of this receptor have been reported and GPR35 mRNAs were detected in several tissues including intestine, lymphocytes, skeletal muscle, pancreatic...
| Schlagworte: | Anti-GPR35, Anti-KYNA receptor, Anti-KYNA receptor, Anti-Kynurenic acid receptor, Anti-Kynurenic acid receptor,... |
| Anwendung: | IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, porcine, murine |
468,00 €
YE 120
Artikelnummer: Cay29720-1
YE 120 is an agonist of G protein-coupled receptor 35 (GPR35) with an EC50 value of 32 nM in a dynamic mass redistribution (DMR) assay using HT-29 cells. It induces beta-arrestin translocation in Tango GPR35-bla U2OS cells (EC50 = 10.2 µM). YE 120 (10 µM) promotes wound closure in YAMC colonic epithelial and IEC-6...
| Schlagworte: | 2-[3-cyano-5-(3,4-dichlorophenyl)-4,5-dimethyl-2(5H)-furanylidene]-propanedinitrile |
| Anwendung: | GPR35 agonist |
| CAS | 383124-82-1 |
| MW: | 330.2 D |
ab 93,00 €
ML-145
Artikelnummer: Cay33534-1
ML-145 is an antagonist of G protein-coupled receptor 35 (GPR35). It inhibits beta-arrestin recruitment induced by the GPR35 agonists zaprinast (Cay-10010421), cromolyn (Cay-21379), and pamoic acid (Cay-13946) in HEK293 cells expressing the human receptor (EC50s = 26, 22, and 8.3 nM, respectively). ML-145 inhibits...
| Schlagworte: | 2-hydroxy-4-[[4-[(5Z)-5-[(2E)-2-methyl-3-phenyl-2-propen-1-ylidene]-4-oxo-2-thioxo-3-thiazolidinyl]-1-oxobutyl]amino]-benz... |
| Anwendung: | GPR35 antagonist |
| CAS | 1164500-72-4 |
| MW: | 482.6 D |
ab 93,00 €
3-Methoxycatechol
Artikelnummer: Cay36535-10
3-Methoxycatechol is a lignan-derived phenol. It is an agonist of G protein-coupled receptor 35 (GPR35) with an EC50 value of 147 µM in a dynamic mass redistribution (DMR) assay using HT-29 cells. Dietary administration of 3-methoxycatechol (2%) alone, or in a model of multiorgan carcinogenesis induced by...
| Schlagworte: | 1,2-Dihydroxy-3-methoxybenzene, 3-Methoxypyrocatechol, NSC 66525, Pyrogallol 1-monomethyl ether, 3-methoxy-1,2-benzenediol |
| Anwendung: | Lignan-derived phenol, GPR35 agonist |
| CAS | 934-00-9 |
| MW: | 140.1 D |
ab 44,00 €
Human GPR35 (G Protein Coupled Receptor 35) ELISA Kit
Artikelnummer: ELK-ELK4839.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human GPR35. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human GPR35. Next,...
| Schlagworte: | GPR35, KYNA receptor, Kynurenic acid receptor, G-protein coupled receptor 35 |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 374,00 €
G-protein coupled receptor 35 (GPR35), human, recombinant
Artikelnummer: CSB-CF881023HU.100
Organism: Homo sapiens (Human). Source: in vitro E.coli expression system. Expression Region: 1-309aa. Protein Length: Full Length. Tag Info: N-terminal 10xHis-tagged. Target Protein Sequence: MNGTYNTCGS SDLTWPPAIK LGFYAYLGVL LVLGLLLNSL ALWVFCCRMQ QWTETRIYMT NLAVADLCLL CTLPFVLHSL RDTSDTPLCQ LSQGIYLTNR YMSISLVTAI...
| Schlagworte: | GPR35, KYNA receptor, Kynurenic acid receptor, G-protein coupled receptor 35, Recombinant Human G-protein coupled receptor... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli in vitro |
| Ursprungsart: | human |
| MW: | 36.9 kD |
ab 1.458,00 €