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Zu "K04276" wurden 17 Artikel gefunden!
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Artikelnummer: ELK-ELK4839.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human GPR35. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human GPR35. Next,...
Schlagworte: | GPR35, KYNA receptor, Kynurenic acid receptor, G-protein coupled receptor 35 |
Anwendung: | ELISA |
Spezies-Reaktivität: | human |
ab 365,00 €
Artikelnummer: Cay17292-10
NPPB is a chloride channel blocker (IC50 = 80 nM) that has also been identified as a GPR35 agonist. It has been shown to activate the GPR35-Galphai/o and GPR35-Galpha16 pathways in HEK293 cells, inducing intracellular calcium mobilization. NPPB has protonophoric activity and has been used to uncouple mitochondrial...
Schlagworte: | HOE 144, Hoechst 144, 5-nitro-2-[(3-phenylpropyl)amino]-benzoic acid |
Anwendung: | GPR35 agonist, chloride channel blocker |
CAS | 107254-86-4 |
MW: | 300.3 D |
ab 76,00 €
Artikelnummer: Cay12046-10
GPR35 is a G protein-coupled receptor that is activated by kynurenic acid and 2-acyl lysophosphatidic acids (e.g., 2-oleoyl lysophosphatidic acid). It is expressed predominantly on immune cells, the brain, and in the gastrointestinal tract. GPR35 is overexpressed in gastric cancer cells. CID-2745687 is a reversible,...
Schlagworte: | ML-194,... |
Anwendung: | GPR35 antagonist |
CAS | 264233-05-8 |
MW: | 395.4 D |
ab 125,00 €
Artikelnummer: Cay23994-25
Lodoxamide is a potent agonist of GPR35 with an EC50 value of 1.61 nM in a beta-arrestin-2 interaction assay using CHO-K1 cells expressing the human receptor. It inhibits histamine release induced by compound 48/80 (Cay-22173), anti-IgE, or A23187 (Cay-11016) in isolated rat peritoneal mast cells (IC50s = 0.1-50 µM)...
Schlagworte: | 2,2'-[(2-chloro-5-cyano-1,3-phenylene)diimino]bis[2-oxo-acetic acid] |
Anwendung: | GPR35 agonist |
CAS | 53882-12-5 |
MW: | 311.6 D |
ab 130,00 €
Artikelnummer: Cay13946-100
Pamoic acid is a potent agonist of GPR35 orphan receptors (EC50 = 79 nM in a beta-arrestin recruitment assay). It induces GPR35 translocation from the plasma membrane to the cytoplasm with an EC50 value of 22 nM. Pamoic acid also increases ERK1/2 phosphorylation in a concentration-dependent manner in U20S cells...
Schlagworte: | Embonic Acid, NSC 30188, NSC 40132, 4,4'-methylenebis[3-hydroxy-2-naphthalenecarboxylic acid] |
Anwendung: | Potent GPR35 agonist |
CAS | 130-85-8 |
MW: | 388.4 D |
ab 65,00 €
Artikelnummer: ARG56529.250
Protein function: Acts as a receptor for kynurenic acid, an intermediate in the tryptophan metabolic pathway. The activity of this receptor is mediated by G-proteins that elicit calcium mobilization and inositol phosphate production through G(qi/o) proteins. [The UniProt Consortium]
Schlagworte: | Anti-GPR35, Anti-KYNA receptor, Anti-Kynurenic acid receptor, Anti-G-protein coupled receptor 35 |
Anwendung: | IHC (paraffin), WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, swine |
656,00 €
Artikelnummer: Cay10007660-1
Many G protein-coupled receptor 35 (GPR35) ligands have recently been identified including kynurenic acid (Cay-16762) and zaprinast (Cay-110010421). Multiple isoforms of this receptor have been reported and GPR35 mRNAs were detected in several tissues including intestine, lymphocytes, skeletal muscle, pancreatic...
Schlagworte: | Anti-GPR35, Anti-KYNA receptor, Anti-KYNA receptor, Anti-Kynurenic acid receptor, Anti-Kynurenic acid receptor,... |
Anwendung: | IHC (paraffin), WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, porcine, murine |
422,00 €
Artikelnummer: ABE-11-8032-25
Protein function: Acts as a receptor for kynurenic acid, an intermediate in the tryptophan metabolic pathway. The activity of this receptor is mediated by G-proteins that elicit calcium mobilization and inositol phosphate production through G(qi/o) proteins. [The UniProt Consortium]
Schlagworte: | Anti-GPR35, Anti-KYNA receptor, Anti-Kynurenic acid receptor, Anti-G-protein coupled receptor 35, Polyclonal Antibody to... |
Anwendung: | WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
134,00 €
-15 %
Rabattaktion
Artikelnummer: ABE-11-8032-100
Protein function: Acts as a receptor for kynurenic acid, an intermediate in the tryptophan metabolic pathway. The activity of this receptor is mediated by G-proteins that elicit calcium mobilization and inositol phosphate production through G(qi/o) proteins. [The UniProt Consortium]
Schlagworte: | Anti-GPR35, Anti-KYNA receptor, Anti-Kynurenic acid receptor, Anti-G-protein coupled receptor 35, Polyclonal Antibody to... |
Anwendung: | WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
387,00 €
328,95 €
Artikelnummer: Cay29720-1
YE 120 is an agonist of G protein-coupled receptor 35 (GPR35) with an EC50 value of 32 nM in a dynamic mass redistribution (DMR) assay using HT-29 cells. It induces beta-arrestin translocation in Tango GPR35-bla U2OS cells (EC50 = 10.2 µM). YE 120 (10 µM) promotes wound closure in YAMC colonic epithelial and IEC-6...
Schlagworte: | 2-[3-cyano-5-(3,4-dichlorophenyl)-4,5-dimethyl-2(5H)-furanylidene]-propanedinitrile |
Anwendung: | GPR35 agonist |
CAS | 383124-82-1 |
MW: | 330.2 D |
ab 84,00 €
Artikelnummer: Cay33534-1
ML-145 is an antagonist of G protein-coupled receptor 35 (GPR35). It inhibits beta-arrestin recruitment induced by the GPR35 agonists zaprinast (Cay-10010421), cromolyn (Cay-21379), and pamoic acid (Cay-13946) in HEK293 cells expressing the human receptor (EC50s = 26, 22, and 8.3 nM, respectively). ML-145 inhibits...
Schlagworte: | 2-hydroxy-4-[[4-[(5Z)-5-[(2E)-2-methyl-3-phenyl-2-propen-1-ylidene]-4-oxo-2-thioxo-3-thiazolidinyl]-1-oxobutyl]amino]-benz... |
Anwendung: | GPR35 antagonist |
CAS | 1164500-72-4 |
MW: | 482.6 D |
ab 84,00 €
Artikelnummer: ELK-ES5614.100
function:Orphan receptor.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed in all adult and fetal tissues examined, including pancreatic islets and skeletal muscle, with relatively higher levels in adult lung, small intestine, colon and stomach., Protein function: Acts as a...
Schlagworte: | Anti-GPR35, Anti-KYNA receptor, Anti-Kynurenic acid receptor, Anti-G-protein coupled receptor 35, GPR35 rabbit pAb |
Anwendung: | WB, IF, ELISA |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, rat, mouse, |
ab 169,00 €