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Zu "K04267" wurden 38 Artikel gefunden!
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Artikelnummer: Cay25637-1
PSB-603 is an antagonist of the adenosine A2B receptor (Ki = 0.553 nM). It is selective for adenosine A2B over A1, A2A, and A3 receptors (Kis = >10,000 nM). It reduces intracellular calcium concentrations in Jurkat T cells expressing the human A2B receptor (IC50 = 1.13 nM). PSB-603 reduces Zika viral plaque...
Schlagworte: | 8-[4-[[4-(4-chlorophenyl)-1-piperazinyl]sulfonyl]phenyl]-3,9-dihydro-1-propyl-1H-purine-2,6-dione |
Anwendung: | Adenosine receptor A2b antagonist |
CAS | 1092351-10-4 |
MW: | 529 D |
ab 52,00 €
Artikelnummer: ELK-ELK3837.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human ADORA2b. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human ADORA2b....
Schlagworte: | ADORA2B, Adenosine receptor A2b |
Anwendung: | ELISA |
Spezies-Reaktivität: | human |
ab 365,00 €
Artikelnummer: ELK-ELK6990.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse ADORA2b. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse ADORA2b....
Schlagworte: | Adora2b, Adenosine receptor A2b |
Anwendung: | ELISA |
Spezies-Reaktivität: | mouse |
ab 365,00 €
Artikelnummer: Cay17127-25
BAY 60-6583 is an adenosine A2B receptor agonist (EC50 = 3 nM for human A2B receptors) that displays selectivity over A1, A2A, and A3 receptors (EC50s = >10 µM). It has been used to decrease superoxide production in neutrophils and to study the role of the A2B receptor in regulating inflammation and mediating...
Schlagworte: | 2-[[6-amino-3,5-dicyano-4-[4-(cyclopropylmethoxy)phenyl]-2-pyridinyl]thio]-acetamide |
Anwendung: | Adenosine A2B receptor agonist |
CAS | 910487-58-0 |
MW: | 379.4 D |
ab 43,00 €
Artikelnummer: Cay21232-25
Adenosine is a purine nucleoside composed of adenine and ribose linked by a glycosidic linkage. It is an endogenous ligand of a family of four adenosine receptors, which serve diverse roles related to smooth muscle tone, central nervous system regulation, and cardiac function. Adenosine is a precursor for adenosine...
Schlagworte: | NSC 7652, 2R-(6-amino-9H-purin-9-yl)-5R-(hydroxymethyl)tetrahydrofuran-3R,4S-diol |
Anwendung: | Endogenous adenosine receptor ligand |
CAS | 58-61-7 |
MW: | 267.2 D |
ab 43,00 €
Artikelnummer: Cay23929-10
PSB-1115 is an antagonist of the adenosine A2B receptor (Ki = 53.4 nM). It is selective for A2B over A1 and A2A receptors, which have Ki values of 2,200 and 24,000 nM, respectively, and over the A3 receptor, which it inhibits only 14% at a concentration of 10 µM. PSB-1115 pre-treatment reduces relaxation of rat...
Schlagworte: | 4-(2,3,6,9-tetrahydro-2,6-dioxo-1-propyl-1H-purin-8-yl)-benzenesulfonic acid, monopotassium salt |
Anwendung: | Adenosine A2B receptor antagonist |
CAS | 409344-71-4 |
MW: | 388.4 D |
ab 109,00 €
Artikelnummer: Cay21690-5
Picotamide is an antiplatelet drug that inhibits both thromboxane A2 (TXA2) receptors (Kd = 325 nM) and TXA2 synthase. It significantly inhibits basal and lipopolysaccharide-stimulated TXA2 synthesis by rat peritoneal macrophages when used at 0.5 mM. Formulations containing picotamide have potential applications in...
Schlagworte: | 4-methoxy-N1,N3-bis(3-pyridinylmethyl)-1,3-benzenedicarboxamide |
Anwendung: | TXA2 receptor antagonist / TXA2 synthase inhibitor |
CAS | 32828-81-2 |
MW: | 376.4 D |
ab 84,00 €
Artikelnummer: Cay17417-1
MRS1706 is a selective adenosine A2B receptor inverse agonist with Ki values of 1.39, 157, 112, and 230 nM for human A2B, A1, A2A, and A3 receptors, respectively.Formal Name: N-(4-acetylphenyl)-2-[4-(2,3,6,9-tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy]-acetamide. CAS Number: 264622-53-9. Molecular...
Schlagworte: | N-(4-acetylphenyl)-2-[4-(2,3,6,9-tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy]-acetamide |
Anwendung: | Selective, potent Adenosine A2B receptor inverse agonist |
CAS | 264622-53-9 |
MW: | 503.6 D |
ab 43,00 €
Artikelnummer: Cay28422-1
Capadenoson is an orally bioavailable, non-nucleoside adenosine (A) receptor partial agonist. It binds selectively to human A1 and A2B (EC50s = 0.66 and 1.1 nM, respectively) over A2A and A3 receptors (EC50s = 1,413 and 240 nM, respectively) expressed in CHO cells. Capadenoson (0.6 µM) decreases electrical...
Schlagworte: | BAY 68-4986,... |
Anwendung: | Adenosine (A) receptor partial agonist |
CAS | 544417-40-5 |
MW: | 520 D |
ab 66,00 €
Artikelnummer: Cay33501-10
MRS1754 is an adenosine A2B receptor antagonist (Ki = 1.97 nM). It is selective for adenosine A2B receptors over adenosine A1, A2A, and A3 receptors (Kis = 403, 503, and 570 nM, respectively). In vivo, MRS1754 (0.5-10 mg/kg) increases 28-day survival, as well as decreases peritoneal bacterial growth and plasma...
Schlagworte: | N-(4-cyanophenyl)-2-[4-(2,3,6,9-tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy]-acetamide |
Anwendung: | Adenosine A2B receptor antagonist |
CAS | 264622-58-4 |
MW: | 486.5 D |
ab 147,00 €
Artikelnummer: ARG63813.100
Protein function: Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. [The UniProt Consortium]
Schlagworte: | Anti-ADORA2B, Anti-Adenosine receptor A2b |
Anwendung: | ELISA, IHC (paraffin) |
Wirt: | Goat |
Spezies-Reaktivität: | human |
784,00 €
Artikelnummer: 600-401-X73
Anti-ADORA2B antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. ADORA2B antibody is human, mouse and rat reactive. At least two isoforms of ADORA2B are known to exist, this antibody will detect both isoforms. ADORA2B antibody is predicted to not cross-react with ADORA2A....
Schlagworte: | Anti-ADORA2B, Anti-Adenosine receptor A2b |
Anwendung: | ELISA, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
684,00 €