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Zu "K04263" wurden 20 Artikel gefunden!
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Artikelnummer: ELK-ELK4649.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human PTGIR. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human PTGIR. Next,...
Schlagworte: | PTGIR, PRIPR, PGI receptor, PGI2 receptor, Prostacyclin receptor, Prostanoid IP receptor, Prostaglandin I2 receptor |
Anwendung: | ELISA |
Spezies-Reaktivität: | human |
ab 365,00 €
Artikelnummer: Cay39027-5
AMX12006 is an antagonist of the prostaglandin E2 (PGE2) receptor subtype EP4 (IC50 = 4.3 nM). It is selective for EP4 over EP1, EP2, and EP3 receptors (IC50s = >10 µM for all). AMX12006 is cytotoxic to MCF-7 and 4T1 breast and CT26 colon cancer cells (IC50s = 46.73, 79.47, and 41.39 µM, respectively). It reduces...
Schlagworte: | 4-[(1S)-1-[[[1-methyl-3-[[3-(trifluoromethyl)phenyl]amino]-1H-indol-2-yl]carbonyl]amino]ethyl]-benzoic acid |
Anwendung: | EP4 receptor (prostaglandin E receptor 4) antagonist |
CAS | 2639775-01-0 |
MW: | 481.5 D |
ab 77,00 €
Artikelnummer: Cay10162-1
Primary pulmonary hypertension (PPH) is a condition of unknown cause that is characterized by increasing pulmonary arterial and vascular resistance. Treprostinil is a stable analog of prostacyclin (Cay-18220) that is used clinically for the treatment of PPH under the trade name Remodulin(TM). The structural...
Schlagworte: | BW 15AU, LRX 15, Rumodolin, U-62840, Uniprost,... |
Anwendung: | Prostacyclin analog, prostaglandin I2 receptor agonist |
CAS | 81846-19-7 |
MW: | 390.5 D |
ab 130,00 €
Artikelnummer: Cay160070-1
The IP Receptor is a class A rhodopsin-like G protein-coupled receptor that mediates the actions of prostaglandin I2 (PGI2). The C-terminal intracellular tail of the IP receptor undergoes isoprenylation and palmitoylation that results in anchoring of the tail to the plasma membrane. The IP receptor is expressed in...
Schlagworte: | Anti-Ptgir, Anti-PGI receptor, Anti-PGI receptor, Anti-PGI2 receptor, Anti-PGI2 receptor, Anti-Prostacyclin receptor,... |
Anwendung: | WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | murine, rat |
422,00 €
Artikelnummer: Cay10005518-1
The IP Receptor is a class A rhodopsin-like G protein-coupled receptor that mediates the actions of prostaglandin I2 (PGI2). The C-terminal intracellular tail of the IP receptor undergoes isoprenylation and palmitoylation that results in anchoring of the tail to the plasma membrane. The IP receptor is expressed in...
Schlagworte: | Anti-PTGIR, Anti-PRIPR, Anti-PGI receptor, Anti-PGI receptor, Anti-PGI2 receptor, Anti-PGI2 receptor, Anti-Prostacyclin... |
Anwendung: | WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, murine, rat |
422,00 €
Artikelnummer: ARG56490.250
Protein function: Receptor for prostacyclin (prostaglandin I2 or PGI2). The activity of this receptor is mediated by G(s) proteins which activate adenylate cyclase. [The UniProt Consortium]
Schlagworte: | Anti-Ptgir, Anti-PGI receptor, Anti-PGI2 receptor, Anti-Prostacyclin receptor, Anti-Prostanoid IP receptor,... |
Anwendung: | WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | mouse |
656,00 €
Artikelnummer: E-AB-60476.120
The protein encoded by this gene is a member of the G-protein coupled receptor family 1 and has been shown to be a receptor for prostacyclin. Prostacyclin, the major product of cyclooxygenase in macrovascular endothelium, elicits a potent vasodilation and inhibition of platelet aggregation through binding to this...
Schlagworte: | Anti-PTGIR, Anti-PRIPR, Anti-PGI receptor, Anti-PGI2 receptor, Anti-Prostacyclin receptor, Anti-Prostanoid IP receptor,... |
Anwendung: | WB, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse |
ab 198,00 €
Artikelnummer: Cay30009-1
Ralinepag is a prostaglandin I2 (PGI2) receptor (IP) agonist (Ki = 3 nM). It is selective for IP over the PGD2 receptor (DP1) and the PGE2 receptor subtypes EP1-4 (Kis = 2,600, 9,600, 611, 143, and 678 nM, respectively, in radioligand binding assays). Ralinepag induces cAMP accumulation in CHO-K1 cells expressing...
Schlagworte: | 2-[[trans-4-[[[[(4-chlorophenyl)phenylamino]carbonyl]oxy]methyl]cyclohexyl]methoxy]-acetic acid |
Anwendung: | Prostanoid IP receptor agonist |
CAS | 1187856-49-0 |
MW: | 431.9 D |
ab 50,00 €
Artikelnummer: G-CAB1849.100
Anwendung: | IHC, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse |
ab 352,00 €
Artikelnummer: ELK-ES6891.100
The protein encoded by this gene is a member of the G-protein coupled receptor family 1 and has been shown to be a receptor for prostacyclin. Prostacyclin, the major product of cyclooxygenase in macrovascular endothelium, elicits a potent vasodilation and inhibition of platelet aggregation through binding to this...
Schlagworte: | Anti-PRIPR, Anti-PTGIR, Anti-PGI receptor, Anti-PGI2 receptor, Anti-Prostacyclin receptor, Anti-Prostanoid IP receptor,... |
Anwendung: | WB, ELISA, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, rat, mouse, |
ab 169,00 €
Artikelnummer: VHPS-7451
Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
Schlagworte: | PRIPR, PTGIR, PGI receptor, PGI2 receptor, Prostacyclin receptor, Prostanoid IP receptor, Prostaglandin I2 receptor |
Anwendung: | RNA quantification |
43,00 €
Artikelnummer: VMPS-5163
Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
Schlagworte: | Ptgir, PGI receptor, PGI2 receptor, Prostacyclin receptor, Prostanoid IP receptor, Prostaglandin I2 receptor |
Anwendung: | RNA quantification |
43,00 €