Zu "K04241" wurden 15 Artikel gefunden!
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CHO-K1/UT2/Galpha15 Stable Cell Line
Artikelnummer: GSC-M00339
The Urotensin II receptor (UT2), also named UTS2R, GPR14, which is expressed in endothelium, smooth muscle, heart and pancreas. Pharmacological inhibition of urotensin II receptor interactions prevents renal insufficiency following renal artery ligation. .
| Schlagworte: | UTS2R, Urotensin-2 receptor, Urotensin II receptor, G-protein coupled receptor 14 |
11.424,00 €
SB-657510
Artikelnummer: Cay42321-10
A urotensin II receptor antagonist (Kis = 61, 17, 30, 65, and 56 nM for the human, monkey, cat, rat, and mouse receptors, respectively), reduces urotensin II-induced increases in the expression of IL1B, IL6, and VCAM1 in EA.hy926 cells at 1 µM, reduces urotensin II-induced adhesion of U937 monocytes to EA.hy926...
| Schlagworte: | 2-bromo-N-[4-chloro-3-[[(3R)-1-methyl-3-pyrrolidinyl]oxy]phenyl]-4,5-dimethoxy-benzenesulfonamide |
| Anwendung: | Urotensin II receptor antagonist |
| CAS | 474960-44-6 |
| MW: | 505.81 D |
ab 216,00 €
Urotensin II (human) (trifluoroacetate salt)
Artikelnummer: Cay24711-1
Urotensin II is a somatostatin-like neuropeptide agonist of the urotensin II receptor (UTR, Ki = 2 nM). It increases intracellular calcium levels in a concentration-dependent manner in HEK293 cells expressing human UTR (EC50 = 0.6 nM). Urotensin II increases the level of reactive oxygen species (ROS) in pulmonary...
| Schlagworte: | hU II,... |
| Anwendung: | Urotensin-2 receptor agonist |
| MW: | 1388.6 D |
325,00 €
Anti-UTS2R
Artikelnummer: E-AB-12485.120
This gene codes high affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system Protein function: High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated...
| Schlagworte: | Anti-UTS2R, Anti-GPR14, Anti-UR-2-R, Anti-UR-II-R, Anti-Urotensin-2 receptor, Anti-Urotensin II receptor, Anti-G-protein... |
| Anwendung: | WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 89,00 €
Palosuran
Artikelnummer: Cay23460-1
Palosuran is an antagonist of the urotensin II receptor (UTR, IC50s = 3.6 and 1,475 nM for CHO cell membranes expressing human and rat recombinant receptors, respectively). It inhibits contraction of isolated rat aortic rings induced by urotensin II (Cay-24711, Cay-24753) in a concentration-dependent manner....
| Schlagworte: | ACT058362, N-[2-[4-hydroxy-4-(phenylmethyl)-1-piperidinyl]ethyl]-N'-(2-methyl-4-quinolinyl)-urea |
| Anwendung: | Urotensin-2 receptor / GPR14 antagonist |
| CAS | 540769-28-6 |
| MW: | 418.5 D |
ab 163,00 €
Anti-UTS2R / GPR14
Artikelnummer: ARG58938.50
Protein function: High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system. [The UniProt Consortium]
| Schlagworte: | Anti-UTS2R, Anti-GPR14, Anti-UR-2-R, Anti-UR-II-R, Anti-Urotensin-2 receptor, Anti-Urotensin II receptor, Anti-G-protein... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
584,00 €
SB-611812
Artikelnummer: Cay33247-1
SB-611812 is an antagonist of the urotensin II receptor (UTR). It binds to recombinant rat UTR (Ki = 121 nM) and inhibits contraction of isolated rat aorta induced by urotensin II (pA2 = 6.59) but not potassium chloride, endothelin-1, angiotensin II, or phenylephrine. SB-611812 (30 mg/kg) decreases myocardial...
| Schlagworte: | 2,6-dichloro-N-[4-chloro-3-[2-(dimethylamino)ethoxy]phenyl]-4-(trifluoromethyl)-benzenesulfonamide |
| Anwendung: | Urotensin 2 receptor antagonist |
| CAS | 345892-71-9 |
| MW: | 491.7 D |
ab 67,00 €
Rat UTS2R (Urotensin 2 Receptor) ELISA Kit
Artikelnummer: ELK-ELK2351.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat UTS2R. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat UTS2R. Next,...
| Schlagworte: | SENR, Gpr14, Uts2r, UR-2-R, UR-II-R, Urotensin-2 receptor, Urotensin II receptor, G-protein coupled receptor 14, G-protein... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | rat |
ab 374,00 €
Human UTS2R Protein, hFc Tag
Artikelnummer: DIM-PME101458.10
Recombinant human UTS2R Protein with C-terminal human Fc tag. UTS2R(Met1-Thr51) hFc(Glu99-Ala330), Protein function: High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system. [The UniProt...
| Schlagworte: | UTR, UTR2, GPR14, UR-2-R |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 31.1 kD |
ab 132,00 €
UTS2R (human) full length protein-synthetic nanodisc
Artikelnummer: DIM-FLP100136.10
Discover a breakthrough in membrane protein research and drug development with DIMA Biotech's Synthetic Nanodiscs. Traditional methods struggle with challenges in obtaining water-soluble and bioactive forms of multi-transmembrane proteins. Our innovative polymer-based Nanodisc platform offers a game-changing...
| Schlagworte: | UTS2R, GPR14, UR-2-R, UR-II-R, Urotensin-2 receptor, Urotensin II receptor, G-protein coupled receptor 14, GPR14, UR-2-R,... |
| Anwendung: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 42.1 kD |
ab 1.317,00 €
Anti-UTS2R
Artikelnummer: CSB-PA272813.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: UTS2R. Antigen Species: Human
| Schlagworte: | Anti-UTS2R, Anti-GPR14, Anti-UR-2-R, Anti-UR-II-R, Anti-Urotensin-2 receptor, Anti-Urotensin II receptor, Anti-G-protein... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 167,00 €
Nanodisc Human UTS2R-Strep Protein
Artikelnummer: G-HDFP872.10
Protein function: High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system. [The UniProt Consortium]
| Schlagworte: | UTS2R, GPR14, UR-2-R, UR-II-R, Urotensin-2 receptor, Urotensin II receptor, G-protein coupled receptor 14 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
1.605,00 €