Zu "K04224" wurden 31 Artikel gefunden!
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Talnetant hydrochloride
Artikelnummer: TGM-T62199-100mg
Description: Talnetant (SB 223412) hydrochloride is a selective NK3 receptor antagonist with a Ki of 1.4 nM in hNK-3-CHO cells. It is 100 times more selective for the hNK-3 receptor than the hNK-2 receptor and shows no affinity for hNK-1 at a concentration of 100 µM. Target: Others. Smiles:...
| Anwendung: | Targets tachykinin receptor 3 (TACR3) |
| CAS | 204519-66-4 |
| MW: | 418.92 D |
ab 1.520,00 €
Antibiotic Sch 60057
Artikelnummer: TGM-T125403-1mg
Description: Antibiotic Sch 60057 is a useful organic compound for research related to life sciences. The catalog number is T125403 and the CAS number is 203061-35-2. Target: Others. Smiles: CC(C)=CCCC(C)(O)CCCC(C)(O)CCCC(C)(O)CCCC(C)(O)CCCC(C)(O)CCC\C(C)=C\CC\C(C)=C\CC\C(C)=C\CO
| Anwendung: | Neurokinin receptor antagonist |
| CAS | 203061-35-2 |
| MW: | 721.161 D |
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Fezolinetant
Artikelnummer: TGM-T15278-100mg
Description: Fezolinetant (ESN-364) is an antagonist of the neurokinin 3 receptor (NK3R). It is used for the treatment of menopausal hot flushes. Target: Neurokinin receptor. Smiles: C[C@H]1N(CCn2c1nnc2-c1nc(C)ns1)C(=O)c1ccc(F)cc1. References: Fraser GL, et al. The NK3 Receptor Antagonist ESN364 Interrupts Pulsatile...
| Schlagworte: | ESN-364 |
| Anwendung: | Targets tachykinin receptor 3 (TACR3) |
| CAS | 1629229-37-3 |
| MW: | 358.39 D |
ab 72,00 €
Pavinetant
Artikelnummer: TGM-T16114-100mg
Description: Pavinetant (MLE-4901) is an orally available neurokinin-3 receptor (NK3R) antagonist used to improve menopausal symptoms. Target: Neurokinin receptor. Smiles: CC[C@H](NC(=O)c1c(NS(C)(=O)=O)c(nc2ccccc12)-c1ccccc1)c1ccccc1. References: Li Y, et al. In vitro assessment of metabolic drug-drug interaction...
| Schlagworte: | AZD2624, MLE-4901, AZD4901 |
| Anwendung: | Targets tachykinin receptor 3 (TACR3) |
| CAS | 941690-55-7 |
| MW: | 459.56 D |
ab 74,00 €
SB-222200
Artikelnummer: TGM-T16849-100mg
Description: SB-222200 is a selective, reversible, and competitive antagonist of the human NK-3 receptor(Ki=4.4 nM). Target: Neurokinin receptor. Smiles: Nc1cccc(CN2C(Cc3ccccc3)C(O)C(O)C(Cc3ccccc3)N(Cc3cccc(N)c3)C2=O)c1. References: Sarau HM, et al. Nonpeptide tachykinin receptor antagonists. II. Pharmacological and...
| Anwendung: | NK3 receptor antagonist |
| CAS | 174635-69-9 |
| MW: | 380.48 D |
ab 34,00 €
Talnetant
Artikelnummer: TGM-T7549-100mg
Description: Talnetant (SB 223412) is a selective, competitive NK3 receptor antagonist that penetrates the brain and modulates mesolimbic and mesocortical dopaminergic neurotransmission. Target: Neurokinin receptor. Smiles: CC[C@H](NC(=O)c1c(O)c(nc2ccccc12)-c1ccccc1)c1ccccc1. References: Dawson L A , Cato K J ,...
| Schlagworte: | SB 223412 |
| Anwendung: | Tachykinin receptor 3 antagonist |
| CAS | 174636-32-9 |
| MW: | 382.45 D |
ab 37,00 €
Anti-TACR3
Artikelnummer: CSB-PA003454.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-NKR, Anti-NK3R, Anti-NK-3R, Anti-TACR3, Anti-NK-3 receptor, Anti-Neurokinin B receptor, Anti-Tachykinin receptor 3,... |
| Anwendung: | ELISA, WB, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 126,00 €
Senktide (trifluoroacetate salt)
Artikelnummer: Cay16721-500
Senktide is a potent, selective agonist of the neuromedin K3 (NK3) receptor (EC50 = 0.5-3 nM). It less potently agonizes the NK1 receptor (EC50 = 35 µM) and is without effect on the NK2 receptor. Senktide is used to study the action of the NK3 receptor in cells and in animals.Formal Name:...
| Schlagworte: | N-(3-carboxy-1-oxopropyl)-L-alpha-aspartyl-L-phenylalanyl-N-methyl-L-phenylalanylglycyl-L-leucyl-L-methioninamide |
| Anwendung: | TACR3 / neuromedin K3 (NK3) receptor agonist |
| MW: | 842 D |
ab 111,00 €
Eledoisin
Artikelnummer: Cay28810-1
Eledoisin is an undecapeptide tachykinin neuropeptide and neurokinin (NK) receptor agonist originally isolated from E. moschata. It binds to NK1 (pD2 = 9.5 and 9.21 in isolated dog carotid artery and guinea pig ileum, respectively), NK2 (pD2 = 8.22 and 7.7 in isolated rabbit pulmonary artery and rat duodenum,...
| Schlagworte: | ELD 950, Moschatin,... |
| Anwendung: | Neuromedin-K receptor agonist |
| CAS | 69-25-0 |
| MW: | 1188.4 D |
ab 117,00 €
Human TACR3 / Neuromedin-K receptor ELISA Kit
Artikelnummer: G-HUFI01412.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
641,00 €
Anti-NK3R
Artikelnummer: 600-401-DC1
Anti-NK3R Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with NK3R from other sources has not been determined. Protein function: This is a receptor for the tachykinin neuropeptide neuromedin-K (neurokinin B). It is associated with G proteins that...
| Schlagworte: | Anti-NKR, Anti-NK3R, Anti-NK-3R, Anti-TACR3, Anti-NK-3 receptor, Anti-Neurokinin B receptor, Anti-Neuromedin-K receptor,... |
| Anwendung: | ELISA, IHC, IFM, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
834,00 €
MLE-4901
Artikelnummer: Cay23587-1
MLE-4901 is an antagonist of the neurokinin-3 (NK3) receptor. It inhibits human liver microsomal CYP3A4/5 with apparent IC50 values of 7.1 and 19.8 µM in midazolam 1'-hydroxylation and testosterone 6beta-hydroxylation assays, respectively.Formal Name:...
| Schlagworte: | AZD 2624, AZD 4901, 3-[(methylsulfonyl)amino]-2-phenyl-N-[(1S)-1-phenylpropyl]-4-quinolinecarboxamide |
| Anwendung: | Neurokinin-3 (NK3) receptor antagonist |
| CAS | 941690-55-7 |
| MW: | 459.6 D |
ab 94,00 €