Zu "K04224" wurden 34 Artikel gefunden!
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CHO-K1/NK3 Stable Cell Line
Artikelnummer: GSC-M00201
Recombinant CHO-K1 cells stably overexpress human tachykinin receptor 3 (NK3) on the surface and contain high levels of G protein Galphaq to couple with the receptor in downstream signaling pathways.
| Schlagworte: | TACR3, NK-3 receptor, Tachykinin receptor 3, Neuromedin-K receptor, Neurokinin B receptor |
11.424,00 €
SB-218795
Artikelnummer: Cay42373-10
An NK3 receptor antagonist (Ki = 0.013 µM), selective for NK3 over NK1 and NK2 receptors (Kis = >100 and 1.221 µM, respectively), inhibits senktide-induced contractions in isolated rabbit iris sphincter muscle preparations (Kb = 43 nM), inhibits substance P-induced contraction of longitudinal and circular smooth...
| Schlagworte: | aR-[[(2-phenyl-4-quinolinyl)carbonyl]amino]-benzeneacetic acid, methyl ester |
| Anwendung: | NK3 receptor (TACR3) antagonist |
| CAS | 174635-53-1 |
| MW: | 396.44 D |
ab 133,00 €
Scyliorhinin II (trifluoroacetate salt) (dogfish)
Artikelnummer: Cay43056-1
An NK3 receptor peptide agonist, binds NK3 receptors in isolated rat cerebral cortex (Ki = 2.5 nM), induces contractions in isolated and perfused carp intestinal bulb smooth muscle strips (EC50 = 39 nM), induces reciprocal hindlimb neck-scratching behavior in mice (ED50 = 0.08 nmol/animal, i.c.v.). Formulation: A...
| Schlagworte: | SCY2, SCYII, Scyliorhinin 2, cyclic (7->13)-disulfide... |
| Anwendung: | NK3 receptor (TACR3) peptide agonist |
| MW: | 1851.1 D |
ab 95,00 €
GR73632 (acetate)
Artikelnummer: Cay43047-5
GR73632 is a peptide neurokinin-1 (NK1) receptor agonist. It potentiates electrically induced contractions in isolated guinea pig vas deferens (EC50 = 2 nM). Intradermal administration of GR73632 (30 nmol/animal) increases scratching behavior in gerbils. It induces foot tapping behavior in gerbils when...
| Schlagworte: | Deamino-Orn-Phe-Phe-Pro-N(Me)Leu-Met-NH2,... |
| Anwendung: | Peptide NK1 receptor agonist |
| MW: | 766.02 D |
ab 216,00 €
Senktide (trifluoroacetate salt)
Artikelnummer: Cay16721-500
Senktide is a potent, selective agonist of the neuromedin K3 (NK3) receptor (EC50 = 0.5-3 nM). It less potently agonizes the NK1 receptor (EC50 = 35 µM) and is without effect on the NK2 receptor. Senktide is used to study the action of the NK3 receptor in cells and in animals.Formal Name:...
| Schlagworte: | N-(3-carboxy-1-oxopropyl)-L-alpha-aspartyl-L-phenylalanyl-N-methyl-L-phenylalanylglycyl-L-leucyl-L-methioninamide |
| Anwendung: | TACR3 / neuromedin K3 (NK3) receptor agonist |
| MW: | 842 D |
ab 122,00 €
Eledoisin
Artikelnummer: Cay28810-1
Eledoisin is an undecapeptide tachykinin neuropeptide and neurokinin (NK) receptor agonist originally isolated from E. moschata. It binds to NK1 (pD2 = 9.5 and 9.21 in isolated dog carotid artery and guinea pig ileum, respectively), NK2 (pD2 = 8.22 and 7.7 in isolated rabbit pulmonary artery and rat duodenum,...
| Schlagworte: | ELD 950, Moschatin,... |
| Anwendung: | Neuromedin-K receptor agonist |
| CAS | 69-25-0 |
| MW: | 1188.4 D |
ab 128,00 €
Human TACR3 / Neuromedin-K receptor ELISA Kit
Artikelnummer: G-HUFI01412.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
698,00 €
Anti-NK3R
Artikelnummer: 600-401-DC1
Anti-NK3R Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with NK3R from other sources has not been determined. Protein function: This is a receptor for the tachykinin neuropeptide neuromedin-K (neurokinin B). It is associated with G proteins that...
| Schlagworte: | Anti-NKR, Anti-NK3R, Anti-NK-3R, Anti-TACR3, Anti-NK-3 receptor, Anti-Neurokinin B receptor, Anti-Neuromedin-K receptor,... |
| Anwendung: | ELISA, IHC, IFM, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
848,00 €
MLE-4901
Artikelnummer: Cay23587-1
MLE-4901 is an antagonist of the neurokinin-3 (NK3) receptor. It inhibits human liver microsomal CYP3A4/5 with apparent IC50 values of 7.1 and 19.8 µM in midazolam 1'-hydroxylation and testosterone 6beta-hydroxylation assays, respectively.Formal Name:...
| Schlagworte: | AZD 2624, AZD 4901, 3-[(methylsulfonyl)amino]-2-phenyl-N-[(1S)-1-phenylpropyl]-4-quinolinecarboxamide |
| Anwendung: | Neurokinin-3 (NK3) receptor antagonist |
| CAS | 941690-55-7 |
| MW: | 459.6 D |
ab 102,00 €
Anti-TACR3 / NK3R
Artikelnummer: ARG59954.100
Protein function: This is a receptor for the tachykinin neuropeptide neuromedin-K (neurokinin B). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: neuromedin-K > substance K > substance P. [The...
| Schlagworte: | Anti-NKR, Anti-NK3R, Anti-TACR3, Anti-NK-3R, Anti-NK-3 receptor, Anti-Neurokinin B receptor, Anti-Tachykinin receptor 3,... |
| Anwendung: | IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
707,00 €
SB 222200
Artikelnummer: Cay29422-10
SB 222200 is a neurokinin-3 (NK3) receptor antagonist (IC50 = 18.4 nM). It is selective for NK3 over NK1 and NK2 receptors (IC50s = 250 and >100,000 nM, respectively). SB 222200 decreases calcium mobilization induced by neurokinin B (Cay-24542) with an IC50 value of 265 nM in HEK293 cells expressing the recombinant...
| Schlagworte: | 3-methyl-2-phenyl-N-[(1S)-1-phenylpropyl]-4-quinolinecarboxamide |
| Anwendung: | NK3 receptor antagonist |
| CAS | 174635-69-9 |
| MW: | 380.5 D |
ab 174,00 €
SCH 60057
Artikelnummer: Cay29239-1
SCH 60057 is a fungal metabolite that has been found in Acremonium and a neurokinin receptor (NK) antagonist (IC50s = 6 and 12 µM for NK1 and NK2, respectively).Formal Name: 3,7,11,15,19,23,27,31,35-nonamethyl-2E,6E,10E,34-hexatriacontatetraene-1,15,19,23,27,31-hexol. CAS Number: 203061-35-2. Molecular Formula:...
| Schlagworte: | 3,7,11,15,19,23,27,31,35-nonamethyl-2E,6E,10E,34-hexatriacontatetraene-1,15,19,23,27,31-hexol |
| Anwendung: | Neurokinin receptor antagonist |
| CAS | 203061-35-2 |
| MW: | 721.1 D |
265,00 €