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Zu "K04224" wurden 23 Artikel gefunden!
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Artikelnummer: Cay39523-10
Fezolinetant is a neurokinin-3 (NK3) receptor antagonist (IC50 = 20 nM). It decreases plasma levels of luteinizing hormone (LH) in castrated cynomolgus monkeys when administered at a dose of 5 mg/kg. Fezolinetant (10 mg/kg) prevents increases in body weight and food intake but does not affect uterine weight or...
Schlagworte: | AS 3472693-00, ESN364,... |
Anwendung: | NK3 receptor antagonist |
CAS | 1629229-37-3 |
MW: | 358.4 D |
ab 135,00 €
Artikelnummer: ARG24108.50
Protein function: This is a receptor for the tachykinin neuropeptide neuromedin-K (neurokinin B). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: neuromedin-K > substance K > substance P. [The...
Schlagworte: | Anti-NKR, Anti-NKR, Anti-NK3R, Anti-TACR3, Anti-NK-3R, Anti-NK-3R, Anti-NK-3 receptor, Anti-NK-3 receptor,... |
Anwendung: | IHC (paraffin), WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse |
552,00 €
Artikelnummer: Cay16721-500
Senktide is a potent, selective agonist of the neuromedin K3 (NK3) receptor (EC50 = 0.5-3 nM). It less potently agonizes the NK1 receptor (EC50 = 35 µM) and is without effect on the NK2 receptor. Senktide is used to study the action of the NK3 receptor in cells and in animals.Formal Name:...
Schlagworte: | N-(3-carboxy-1-oxopropyl)-L-alpha-aspartyl-L-phenylalanyl-N-methyl-L-phenylalanylglycyl-L-leucyl-L-methioninamide |
Anwendung: | TACR3 / neuromedin K3 (NK3) receptor agonist |
MW: | 842 D |
ab 109,00 €
Artikelnummer: Cay28810-1
Eledoisin is an undecapeptide tachykinin neuropeptide and neurokinin (NK) receptor agonist originally isolated from E. moschata. It binds to NK1 (pD2 = 9.5 and 9.21 in isolated dog carotid artery and guinea pig ileum, respectively), NK2 (pD2 = 8.22 and 7.7 in isolated rabbit pulmonary artery and rat duodenum,...
Schlagworte: | ELD 950, Moschatin,... |
Anwendung: | Neuromedin-K receptor agonist |
CAS | 69-25-0 |
MW: | 1188.4 D |
ab 115,00 €
Artikelnummer: G-HUFI01412.96
Anwendung: | ELISA |
Spezies-Reaktivität: | human |
641,00 €
Artikelnummer: 600-401-DC1
Anti-NK3R Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with NK3R from other sources has not been determined. Protein function: This is a receptor for the tachykinin neuropeptide neuromedin-K (neurokinin B). It is associated with G proteins that...
Schlagworte: | Anti-NKR, Anti-NK3R, Anti-NK-3R, Anti-TACR3, Anti-NK-3 receptor, Anti-Neurokinin B receptor, Anti-Neuromedin-K receptor,... |
Anwendung: | ELISA, IHC, IFM, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse |
684,00 €
Artikelnummer: Cay23587-1
MLE-4901 is an antagonist of the neurokinin-3 (NK3) receptor. It inhibits human liver microsomal CYP3A4/5 with apparent IC50 values of 7.1 and 19.8 µM in midazolam 1'-hydroxylation and testosterone 6beta-hydroxylation assays, respectively.Formal Name:...
Schlagworte: | AZD 2624, AZD 4901, 3-[(methylsulfonyl)amino]-2-phenyl-N-[(1S)-1-phenylpropyl]-4-quinolinecarboxamide |
Anwendung: | Neurokinin-3 (NK3) receptor antagonist |
CAS | 941690-55-7 |
MW: | 459.6 D |
ab 92,00 €
Artikelnummer: E-AB-61592.120
This gene belongs to a family of genes that function as receptors for tachykinins. Receptor affinities are specified by variations in the 5'-end of the sequence. The receptors belonging to this family are characterized by interactions with G proteins and 7 hydrophobic transmembrane regions. This gene encodes the...
Schlagworte: | Anti-NKR, Anti-NK3R, Anti-NK-3R, Anti-TACR3, Anti-NK-3 receptor, Anti-Neurokinin B receptor, Anti-Tachykinin receptor 3,... |
Anwendung: | WB, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
ab 198,00 €
Artikelnummer: ARG59954.100
Protein function: This is a receptor for the tachykinin neuropeptide neuromedin-K (neurokinin B). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: neuromedin-K > substance K > substance P. [The...
Schlagworte: | Anti-NKR, Anti-NK3R, Anti-TACR3, Anti-NK-3R, Anti-NK-3 receptor, Anti-Neurokinin B receptor, Anti-Tachykinin receptor 3,... |
Anwendung: | IHC (paraffin), WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
624,00 €
Artikelnummer: Cay29422-10
SB 222200 is a neurokinin-3 (NK3) receptor antagonist (IC50 = 18.4 nM). It is selective for NK3 over NK1 and NK2 receptors (IC50s = 250 and >100,000 nM, respectively). SB 222200 decreases calcium mobilization induced by neurokinin B (Cay-24542) with an IC50 value of 265 nM in HEK293 cells expressing the recombinant...
Schlagworte: | 3-methyl-2-phenyl-N-[(1S)-1-phenylpropyl]-4-quinolinecarboxamide |
Anwendung: | NK3 receptor antagonist |
CAS | 174635-69-9 |
MW: | 380.5 D |
ab 158,00 €
Artikelnummer: Cay29239-1
SCH 60057 is a fungal metabolite that has been found in Acremonium and a neurokinin receptor (NK) antagonist (IC50s = 6 and 12 µM for NK1 and NK2, respectively).Formal Name: 3,7,11,15,19,23,27,31,35-nonamethyl-2E,6E,10E,34-hexatriacontatetraene-1,15,19,23,27,31-hexol. CAS Number: 203061-35-2. Molecular Formula:...
Schlagworte: | 3,7,11,15,19,23,27,31,35-nonamethyl-2E,6E,10E,34-hexatriacontatetraene-1,15,19,23,27,31-hexol |
Anwendung: | Neurokinin receptor antagonist |
CAS | 203061-35-2 |
MW: | 721.1 D |
238,00 €
Artikelnummer: Cay29699-100
Talnetant is an antagonist of the neurokinin-3 (NK3) receptor (Ki = 1 nM). It is selective for NK3 over NK1 and NK2 receptors (Kis = 144 and >100,000 nM, respectively, in CHO cells expressing recombinant human receptors). Talnetant inhibits calcium mobilization induced by neurokinin B (Cay-24542) in HEK293 cells...
Schlagworte: | SB-223412, 3-hydroxy-2-phenyl-N-[(1S)-1-phenylpropyl]-4-quinolinecarboxamide |
Anwendung: | Tachykinin receptor 3 antagonist |
CAS | 174636-32-9 |
MW: | 382.5 D |
ab 109,00 €