Zu "K04222" wurden 105 Artikel gefunden!
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Hemokinin 1-d10 (human) (trifluoroacetate salt)
Artikelnummer: Cay44813-1
An internal standard for the quantification of hemokinin 1 by GC- or LC-MS. SMILES:...
| Schlagworte: | HK-1-d10, Tachykinin-4 (57-67)-d10,... |
| Anwendung: | GC-MS, LC-MS internal standard, quantification, NK1 receptor agonist |
| MW: | 1195.47 D |
ab 383,00 €
Substance P-d10 (trifluoroacetate salt)
Artikelnummer: Cay44814-1
An internal standard for the quantification of substance P by GC- or LC-MS. SMILES:...
| Schlagworte: | SP-d10,... |
| Anwendung: | GC-MS, LC-MS internal standard, quantification, NK1 receptor agonist |
| MW: | 1357.71 D |
ab 105,00 €
Anti-NKR1 / Neurokinin 1 Receptor / TACR1, clone AFBH-20
Artikelnummer: NSJ-FY12839
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. NKR1 antibody detects Neurokinin 1 receptor, a G protein-coupled receptor (GPCR) encoded by the TACR1 gene on chromosome 2p12 that mediates the biological effects of the neuropeptide Substance P. This...
| Schlagworte: | Anti-TACR1, Anti-NK-1 receptor, Anti-Substance-P receptor, Anti-Tachykinin receptor 1, NKR1 Antibody / Neurokinin 1... |
| Anwendung: | IP, IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
Physalaemin (frog) (trifluoroacetate salt)
Artikelnummer: Cay43045-1
A peptide antagonist of the NK1 receptor (Ki = 1.51 nM), selective for the NK1 receptor over the NK3 receptor (Ki = 457 nM), increases the percentage of cell clusters displaying neurite outgrowth and inhibits toxicity induced by amyloid-beta peptides in NB41A3 cells at 2.5 µM, induces contraction in isolated and...
| Schlagworte: | L-5-oxo-L-prolyl-L-alanyl-L-aspartyl-L-prolyl-L-asparaginyl-L-lysyl-L-phenylalanyl-L-tyrosylglycyl-L-leucyl-methioninamide... |
| Anwendung: | NK1 receptor (TACR1, Substance-P receptor) peptide antagonist |
| CAS | 4705-64-0 |
| MW: | 1265.45 D |
ab 116,00 €
Spantide II (trifluoroacetate salt)
Artikelnummer: Cay43054-1
A peptide antagonist of NK1 and NK2 receptors (Kis = 2.4 and 19.05 nM, respectively), induces histamine release from isolated rat mast cells (EC50 = 3.2 µM), inhibits bombesin-induced contractions in isolated and perfused guinea pig taenia coli at 10 µM, decreases ear swelling in a mouse model of...
| Schlagworte: | [D-NicLys1,3-Pal3,D-Cl2Phe5,Asn6,D-Trp7,9,Nle11]-Substance P,... |
| Anwendung: | NK1 / NK2 receptor peptide antagonist |
| MW: | 1668.79 D |
ab 112,00 €
Spantide I (trifluoroacetate salt)
Artikelnummer: Cay43079-10
A peptide antagonist of the NK1 receptor (Ki = 177.83 nM), selective for NK1 receptors over NK1 and NK3 receptors (Kis = 5,000 and >10,000 nM, respectively), induces histamine release from isolated rat mast cells (EC50 = 2.5 µM), inhibits neurokinin B-induced contractions in isolated and perfused guinea pig taenia...
| Schlagworte: | [Arg1,Trp7,9,Leu11] Substance P, DADTL, SPA I,... |
| Anwendung: | NK1 receptor (TACR1, Substance-P receptor) peptide antagonist |
| MW: | 1497.82 D |
ab 229,00 €
Scyliorhinin I (dogfish) (trifluoroacetate salt)
Artikelnummer: Cay43081-1
An NK1 and NK2 receptor peptide agonist, binds to membrane preparations of rat submandibular gland and hamster urinary bladder (Kis = 0.9 and 2 nM, respectively), tissues that endogenously express high levels of NK1 and NK2 receptors, respectively, increases intracellular levels of IP3 in KNRK rat kidney cells...
| Schlagworte: | Ala-Lys-Phe-Asp-Lys-Phe-Tyr-Gly-Leu-Met-NH2,... |
| Anwendung: | NK1 / NK2 receptor peptide agonist |
| MW: | 1218.48 D |
ab 137,00 €
Hemokinin 1 (mouse, rat) (trifluoroacetate salt)
Artikelnummer: Cay43053-1
A tachykinin neuropeptide and NK1 receptor agonist, binds to NK1 receptors (Ki = 0.175 nM) and induces contractions in isolated rat urinary bladder (EC50 = 100 nM), knockdown of Tac4 inhibits neurogenic inflammation-induced mechanical and thermal hypersensitivity and visceral nocifensive behavior in mice, Tac4-/-...
| Schlagworte: | Arg-Ser-Arg-Thr-Arg-Gln-Phe-Tyr-Gly-Leu-Met-NH2,... |
| Anwendung: | Tachykinin neuropeptide, NK1 receptor agonist |
| MW: | 1413.67 D |
ab 60,00 €
RHRTPMFYGLM-NH2 (trifluoroacetate salt)
Artikelnummer: Cay43089-1
A derivative of C14TKL-1. Formulation: A solid. InChI:...
| Schlagworte: | (S)-1-(L-arginyl-L-histidyl-L-arginyl-L-threonyl)-N-((S)-1-(((S)-1-(((S)-1-((2-(((S)-1-(((S)-1-amino-4-(methylthio)-1-oxob... |
| Anwendung: | C14TKL-1 derivative |
| MW: | 1407.72 D |
ab 82,00 €
Aprepitant
Artikelnummer: Cay14867-5
Aprepitant an antiemetic and antagonist of the neurokinin-1 (NK1) receptor (Ki = 3 nM, IC50 = 0.09 nM for the human receptor). It is selective for NK1 over NK3 receptors (Ki = 454.1 nM for human NK3). In vivo, aprepitant (1 mg/kg) prevents plasma extravasation into the esophagus of guinea pigs induced by substance P...
| Schlagworte: | Emend, L-754,030, MK-869, ONO-7436,... |
| Anwendung: | NK-1 receptor antagonist |
| CAS | 170729-80-3 |
| MW: | 534.4 D |
ab 58,00 €
Aprepitant
Artikelnummer: TGM-T1743-50mg
Description: Aprepitant (Aprepitant`) is a Substance P/Neurokinin-1 Receptor Antagonist. The mechanism of action of aprepitant is as a Neurokinin 1 Antagonist, and Cytochrome P450 3A4 Inhibitor, and Cytochrome P450 2C9 Inducer, and Cytochrome P450 3A4 Inducer. Target: Neurokinin receptor, HIV Protease,...
| Schlagworte: | Aprepitant`, MK-0869, L-754030, MK-869 |
| Anwendung: | Targets tachykinin receptor 1 (TACR1) |
| CAS | 170729-80-3 |
| MW: | 534.43 D |
ab 46,00 €
Substance P (trifluoroacetate salt)
Artikelnummer: Cay24035-5
Substance P is tachykinin neuropeptide that selectively binds to neurokinin 1 (NK1) receptors (Kis = 0.14 and 300 nM for NK1 and NK3, respectively) and has diverse biological activities. It is an endogenous peptide expressed in the central and peripheral nervous systems, including the enteric nervous system and in...
| Schlagworte: | substance p, trifluoroacetate salt |
| Anwendung: | Endogenous TACR1 ligand, neuropeptide |
| CAS | 148470-19-3 |
| MW: | 1347.6 D |
ab 69,00 €