Zu "K04222" wurden 107 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
NEU
Substance P-d10 (trifluoroacetate salt)
Artikelnummer: Cay44814-1
An internal standard for the quantification of substance P by GC- or LC-MS. SMILES:...
| Schlagworte: | SP-d10,... |
| Anwendung: | GC-MS, LC-MS internal standard, quantification, NK1 receptor agonist |
| MW: | 1357.71 D |
ab 102,00 €
NEU
Hemokinin 1-d10 (human) (trifluoroacetate salt)
Artikelnummer: Cay44813-1
An internal standard for the quantification of hemokinin 1 by GC- or LC-MS. SMILES:...
| Schlagworte: | HK-1-d10, Tachykinin-4 (57-67)-d10,... |
| Anwendung: | GC-MS, LC-MS internal standard, quantification, NK1 receptor agonist |
| MW: | 1195.47 D |
ab 371,00 €
Anti-NKR1 / Neurokinin 1 Receptor / TACR1, clone AFBH-20
Artikelnummer: NSJ-FY12839
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. NKR1 antibody detects Neurokinin 1 receptor, a G protein-coupled receptor (GPCR) encoded by the TACR1 gene on chromosome 2p12 that mediates the biological effects of the neuropeptide Substance P. This...
| Schlagworte: | Anti-TACR1, Anti-NK-1 receptor, Anti-Substance-P receptor, Anti-Tachykinin receptor 1, NKR1 Antibody / Neurokinin 1... |
| Anwendung: | IP, IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
CHO-K1/NK1 Stable Cell Line
Artikelnummer: GSC-M00199
Tachykinins are peptides sharing the common C-terminal amino acid sequence Phe-X-Gly-Leu-Met-NH2. This neuropeptide family is composed of substance P, neurokinin A, and neurokinin B, which are widely distributed in mammalian central and peripheral nervous systems. It plays a role as both a neurotransmitter and a...
| Schlagworte: | TACR1, NK-1 receptor, Substance-P receptor, Tachykinin receptor 1 |
11.424,00 €
Physalaemin (frog) (trifluoroacetate salt)
Artikelnummer: Cay43045-1
A peptide antagonist of the NK1 receptor (Ki = 1.51 nM), selective for the NK1 receptor over the NK3 receptor (Ki = 457 nM), increases the percentage of cell clusters displaying neurite outgrowth and inhibits toxicity induced by amyloid-beta peptides in NB41A3 cells at 2.5 µM, induces contraction in isolated and...
| Schlagworte: | L-5-oxo-L-prolyl-L-alanyl-L-aspartyl-L-prolyl-L-asparaginyl-L-lysyl-L-phenylalanyl-L-tyrosylglycyl-L-leucyl-methioninamide... |
| Anwendung: | NK1 receptor (TACR1, Substance-P receptor) peptide antagonist |
| CAS | 4705-64-0 |
| MW: | 1265.45 D |
ab 112,00 €
Spantide II (trifluoroacetate salt)
Artikelnummer: Cay43054-1
A peptide antagonist of NK1 and NK2 receptors (Kis = 2.4 and 19.05 nM, respectively), induces histamine release from isolated rat mast cells (EC50 = 3.2 µM), inhibits bombesin-induced contractions in isolated and perfused guinea pig taenia coli at 10 µM, decreases ear swelling in a mouse model of...
| Schlagworte: | [D-NicLys1,3-Pal3,D-Cl2Phe5,Asn6,D-Trp7,9,Nle11]-Substance P,... |
| Anwendung: | NK1 / NK2 receptor peptide antagonist |
| MW: | 1668.79 D |
ab 108,00 €
Spantide I (trifluoroacetate salt)
Artikelnummer: Cay43079-10
A peptide antagonist of the NK1 receptor (Ki = 177.83 nM), selective for NK1 receptors over NK1 and NK3 receptors (Kis = 5,000 and >10,000 nM, respectively), induces histamine release from isolated rat mast cells (EC50 = 2.5 µM), inhibits neurokinin B-induced contractions in isolated and perfused guinea pig taenia...
| Schlagworte: | [Arg1,Trp7,9,Leu11] Substance P, DADTL, SPA I,... |
| Anwendung: | NK1 receptor (TACR1, Substance-P receptor) peptide antagonist |
| MW: | 1497.82 D |
ab 221,00 €
Scyliorhinin I (dogfish) (trifluoroacetate salt)
Artikelnummer: Cay43081-1
An NK1 and NK2 receptor peptide agonist, binds to membrane preparations of rat submandibular gland and hamster urinary bladder (Kis = 0.9 and 2 nM, respectively), tissues that endogenously express high levels of NK1 and NK2 receptors, respectively, increases intracellular levels of IP3 in KNRK rat kidney cells...
| Schlagworte: | Ala-Lys-Phe-Asp-Lys-Phe-Tyr-Gly-Leu-Met-NH2,... |
| Anwendung: | NK1 / NK2 receptor peptide agonist |
| MW: | 1218.48 D |
ab 133,00 €
Hemokinin 1 (mouse, rat) (trifluoroacetate salt)
Artikelnummer: Cay43053-1
A tachykinin neuropeptide and NK1 receptor agonist, binds to NK1 receptors (Ki = 0.175 nM) and induces contractions in isolated rat urinary bladder (EC50 = 100 nM), knockdown of Tac4 inhibits neurogenic inflammation-induced mechanical and thermal hypersensitivity and visceral nocifensive behavior in mice, Tac4-/-...
| Schlagworte: | Arg-Ser-Arg-Thr-Arg-Gln-Phe-Tyr-Gly-Leu-Met-NH2,... |
| Anwendung: | Tachykinin neuropeptide, NK1 receptor agonist |
| MW: | 1413.67 D |
ab 58,00 €
RHRTPMFYGLM-NH2 (trifluoroacetate salt)
Artikelnummer: Cay43089-1
A derivative of C14TKL-1. Formulation: A solid. InChI:...
| Schlagworte: | (S)-1-(L-arginyl-L-histidyl-L-arginyl-L-threonyl)-N-((S)-1-(((S)-1-(((S)-1-((2-(((S)-1-(((S)-1-amino-4-(methylthio)-1-oxob... |
| Anwendung: | C14TKL-1 derivative |
| MW: | 1407.72 D |
ab 79,00 €
Lanepitant (hydrochloride)
Artikelnummer: Cay43044-1
Lanepitant is a neurokinin-1 (NK1) receptor antagonist (Ki = 0. nM). It inhibits Ac-[Arg6,Sar9,Met(O2)11]-substance P6-11-induced increases in tail biting and scratching in mice when administered at doses of 1, 5, or 10 mg/kg. Lanepitant (10 mg/kg) inhibits late-phase formalin-induced increases in paw licking in...
| Schlagworte: | LY303870, (R)-N-[2-[acetyl[(2-methoxyphenyl)methyl]amino]-1-(1H-indol-3-ylmethyl)ethyl]-[1,4'-bipiperidine]-1'-acetamide,... |
| Anwendung: | NK1 receptor antagonist |
| CAS | 170508-05-1 |
| MW: | 632.7 D |
ab 290,00 €
Befetupitant
Artikelnummer: Cay43004-1
Befetupitant is a neurokinin-1 (NK1) receptor antagonist (Ki = 1 nM). It inhibits GR73632-induced foot tapping in gerbils (ID50 = 0. mg/kg). Topical administration of befetupitant (0. or 1. mg/ml for four days) decreases hemangiogenesis and lymphangiogenesis but induces corneal opacity, stromal leukocyte...
| Schlagworte: | Ro 67-5930, N,a,a-trimethyl-N-[4-(2-methylphenyl)-6-(4-morpholinyl)-3-pyridinyl]-3,5-bis(trifluoromethyl)-benzeneacetamide |
| Anwendung: | NK1 receptor antagonist |
| CAS | 290296-68-3 |
| MW: | 565.56 D |
ab 705,00 €