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Zu "K04218" wurden 60 Artikel gefunden!
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Artikelnummer: GSC-M00325
Recombinant CHO-K1 cells stably overexpress human somatostatin receptor 2 (SST2) on the surface and contain high levels of G protein Galphai to couple with the receptor in downstream signaling pathways.
| Schlagworte: | SSTR2, SRIF-1, Somatostatin receptor type 2 |
11.424,00 €
Artikelnummer: Cay23757-1
Octreotide is an octapeptide analog of somatostatin that binds to somatostatin receptors (SSTRs) with a higher affinity for the somatostatin subgroup 2 receptors, SST2, SST3, and SST5 (Kis = 875, 0.57, 26.8, >1,000, and 6.8 nM for SST1-5 receptors, respectively). Within subgroup 2 SSTRs, it selectively binds to SST2...
| Schlagworte: | SMS 201-995,... |
| Anwendung: | Somatostatin analog |
| MW: | 1079.3 D |
ab 49,00 €
Artikelnummer: Cay24092-1
Pasireotide is a somatostatin receptor (SSTR) agonist that binds selectively to SST1, SST2, SST3, and SST5 over SST4 (IC50s = 9.3, 1, 1.5, 0.16, and >100 nM, respectively, for human recombinant receptors). It dose-dependently inhibits growth hormone release stimulated by growth hormone-releasing hormone (GHRH) in...
| Schlagworte: | SOM230,... |
| Anwendung: | Somatostatin receptor agonist |
| MW: | 1313.4 D |
ab 235,00 €
Artikelnummer: Cay24084-5
Lanreotide is a peptide analog of somatostatin that binds to somatostatin receptors (SSTRs) with a higher affinity for the somatostatin subgroup 2 receptors SST2, SST3, and SST5 (IC50s = 0.5-1.8, 43-107, and 5.6-32 nM, respectively) than for the subgroup 1 receptors, SST1 and SST4 (IC50s = 500-2,330 and 66-2,100 nM,...
| Schlagworte: | BIM23014, 3-(2-naphthalenyl)-D-alanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-valyl-L-cysteinyl-cyclic... |
| Anwendung: | Somatostatin receptor agonist, somatostatin analog |
| CAS | 127984-74-1 |
| MW: | 1096.3 D |
ab 49,00 €
Artikelnummer: G-HUFI01864.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
698,00 €
Artikelnummer: Cay25074-500
Cortistatin-14 is an endogenous neuropeptide agonist of somatostatin receptors (IC50s = 0.5-18.2 nM for human SST1-SST5 receptors expressed in CCL39 cells). It is expressed in GABAergic interneurons in the cortex and hippocampus. Cortistatin-14 competitively inhibits hexarelin binding to human growth hormone...
| Schlagworte: | L-prolyl-L-cysteinyl-L-lysyl-L-asparaginyl-L-phenylalanyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-threonyl-L-phenylalanyl-L-... |
| Anwendung: | Endogenous neuropeptide, somatostatin receptor agonist |
| MW: | 1721 D |
ab 163,00 €
Artikelnummer: ARG41433.100
Protein function: Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by...
| Schlagworte: | Anti-SS2R, Anti-SSTR2, Anti-SS2-R, Anti-SRIF-1, Anti-SS-2-R, Anti-Somatostatin receptor type 2 |
| Anwendung: | IHC (paraffin), IP, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
658,00 €
Artikelnummer: ATA-HPA007264.100
Protein function: Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by...
| Schlagworte: | Anti-SS2R, Anti-SSTR2, Anti-SS2-R, Anti-SRIF-1, Anti-SS-2-R, Anti-Somatostatin receptor type 2 |
| Anwendung: | WB, IHC, ICC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 330,00 €
Artikelnummer: Cay37343-1
CYN 154806 is a cyclic peptide somatostatin receptor 2 (SST2) antagonist (IC50 = 2.62 nM). It is selective for SST2 over SST1, SST3, SST4, and SST5 (IC50s = 3,890, 851, 1,737, and 331 nM, respectively). CYN 154806 inhibits SST-induced increases in extracellular acidification (EAR) in CHO-K1 cells expressing...
| Schlagworte: | Ac-4NO2-Phe-c(D-Cys-Tyr-D-Trp-Lys-Thr-Cys)-D-Tyr-NH2 |
| Anwendung: | SST2 antagonist |
| MW: | 1197.3 D |
ab 151,00 €
Artikelnummer: CSB-CF022725HU.100
Organism: Homo sapiens (Human). Source: in vitro E.coli expression system. Expression Region: 1-369aa. Protein Length: Full Length. Tag Info: N-terminal 10xHis-tagged. Target Protein Sequence: MDMADEPLNG SHTWLSIPFD LNGSVVSTNT SNQTEPYYDL TSNAVLTFIY FVVCIIGLCG NTLVIYVILR YAKMKTITNI YILNLAIADE LFMLGLPFLA MQVALVHWPF...
| Schlagworte: | SS2R, SS2-R, SSTR2, SS-2-R, SRIF-1, Somatostatin receptor type 2, Recombinant Human Somatostatin receptor type 2 (SSTR2) |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli in vitro |
| Ursprungsart: | human |
| MW: | 47.4 kD |
ab 943,00 €
Artikelnummer: CSB-MP022725HU.1
Organism: Homo sapiens (Human). Source: Mammalian cell. Expression Region: 1-369aa. Protein Length: Full Length. Tag Info: C-terminal 6xHis-tagged (This tag can be tested only under denaturing conditions). Target Protein Sequence: MDMADEPLNG SHTWLSIPFD LNGSVVSTNT SNQTEPYYDL TSNAVLTFIY FVVCIIGLCG NTLVIYVILR...
| Schlagworte: | SS2R, SS2-R, SSTR2, SS-2-R, SRIF-1, Somatostatin receptor type 2, Recombinant Human Somatostatin receptor type 2... |
| Anwendung: | Active protein |
| Exprimiert in: | Mammalian cells |
| Ursprungsart: | human |
| MW: | 42.5 kD |
ab 526,00 €
Artikelnummer: DIM-DMC100428.10
Protein function: Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by...
| Schlagworte: | Anti-SRIF-1, Anti-SS2R, Anti-SSTR2 antibody(DMC428), IgG1 Chimeric mAb |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €