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Zu "K04214" wurden 47 Artikel gefunden!
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NEU
Artikelnummer: Cay39901-1
beta-Funaltrexamine is an irreversible µ- and kappa1-opioid receptor antagonist (Kis = 0.3 and 0.2 nM, respectively). It is selective for µ- and kappa1-opioid receptors over the delta-opioid receptor (Ki = 12.8 nM). beta-Funaltrexamine also reversibly inhibits electricity-induced twitches of isolated guinea pig...
Schlagworte: | Naltrexone fumarate methyl ester, beta-FNA,... |
Anwendung: | Irreversible µ-/kappa1-opioid receptor antagonist |
CAS | 72786-10-8 |
MW: | 491 D |
ab 141,00 €
Artikelnummer: Cay40145-10
GR89696 is a kappa-opioid receptor agonist. It inhibits twitch responses in isolated mouse vas deferens (IC50 = 0.12 nM), an effect that can be reversed by the kappa-opioid receptor antagonist norbinaltorphimine (nor-BNI). In vivo, GR89696 reduces acetylcholine-induced writhing in mice (ED50 = 0.0005 mg/kg). It...
Schlagworte: | 4-[2-(3,4-dichlorophenyl)acetyl]-3-(1-pyrrolidinylmethyl)-1-piperazinecarboxylic acid, methyl ester, (2E)-2-butenedioate |
Anwendung: | Kappa-opioid receptor agonist |
CAS | 126766-32-3 |
MW: | 530.4 D |
ab 114,00 €
Artikelnummer: ELK-ELK7389.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse OPRk1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse OPRk1. Next,...
Schlagworte: | Oprk1, KOR-1, MSL-1, K-OR-1, Kappa-type opioid receptor |
Anwendung: | ELISA |
Spezies-Reaktivität: | mouse |
ab 365,00 €
Artikelnummer: Cay39827-1
Naloxone benzoylhydrazone is an antagonist of µ-, kappa1-, and delta-opioid receptors (pA2s = 8.82, 7.45, and 7.76, respectively, for the mouse receptors). It is also an agonist of the kappa3-opioid receptor (IC50 = 0.7 nM for the guinea pig receptor). Naloxone benzoylhydrazone (1 µg/animal, i.c.v.) inhibits...
Schlagworte: | 2-[(5alpha)-4,5-epoxy-3,14-dihydroxy-17-(2-propenyl)ylidene]hydrazide, benzoic acid |
Anwendung: | Opioid receptor antagonist |
CAS | 119630-94-3 |
MW: | 445.5 D |
ab 35,00 €
Artikelnummer: Cay39856-500
Mitraciliatine is an alkaloid that has been found in M. speciosa (Kratom in Thai) and is a µ-opioid receptor (MOR) partial agonist and kappa-opioid receptor (KOR) agonist. It is selective for MOR and KOR over the delta-opioid receptor (DOR, EC50s = 228, 218, and >1,000 nM, respectively, for the mouse receptors in a...
Schlagworte: | (alphaE,2S,3R,12bR)-3-ethyl-1,2,3,4,6,7,12,12b-octahydro-8-methoxy-alpha-(methoxymethylene)-indolo[2,3-a]quinolizine-2-ace... |
Anwendung: | Alkaloid, µ-opioid receptor partial agonist, kappa-opioid receptor agonist |
CAS | 14509-92-3 |
MW: | 398.5 D |
ab 395,00 €
Artikelnummer: Cay23582-5
Salvinorin B (Cay-23582) is an analytical reference standard categorized as a diterpene. Salvinorin B is a presumptive metabolite of salvinorin A (Cay-38208, Cay-11487). It has been found in S. divinorum, a plant with hallucinogenic properties. This product is intended for research and forensic applications.Formal...
Schlagworte: | Divinorin B,... |
Anwendung: | Kappa-type opioid receptor agonist |
CAS | 92545-30-7 |
MW: | 390.4 D |
ab 53,00 €
Artikelnummer: Cay36795-1
Nalfurafine (hydrochloride) (Cay-36795) is an analytical reference standard categorized as an opioid. Naflurafine decreases ethanol consumption in male mice and increases ethanol consumption in female mice. It is regulated as a Schedule II compound in the United States. This product is intended for research and...
Schlagworte: | TRK-820,... |
Anwendung: | Analytical reference standard, opioid, antipruritic, kappa-opioid receptor agonist |
CAS | 152658-17-8 |
MW: | 513 D |
ab 180,00 €
Artikelnummer: Cay23186-1
Nalfurafine (Cay-23186) is an analytical reference standard categorized as an opioid. Naflurafine decreases ethanol consumption in male mice and increases ethanol consumption in female mice. It is regulated as a Schedule II compound in the United States. This product is intended for research and forensic...
Schlagworte: | TRK-820,... |
Anwendung: | Analytical reference standard, kappa-Opioid receptor agonist, antipruritic |
CAS | 152657-84-6 |
MW: | 476.6 D |
ab 161,00 €
Artikelnummer: NSJ-R34964-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: KOR, OPRK, OPRK1 Protein function: G-protein coupled opioid receptor that functions as receptor for endogenous alpha-neoendorphins and dynorphins, but has low affinity for beta-endorphins. Also...
Schlagworte: | Anti-OPRK, Anti-OPRK1, Anti-KOR-1, Anti-K-OR-1, Anti-Kappa-type opioid receptor, Kappa opioid receptor Antibody |
Anwendung: | WB, ELISA (peptide) |
Wirt: | Goat |
Spezies-Reaktivität: | human |
755,00 €
Artikelnummer: Cay16945-25
SCH 202676 is a reversible inhibitor of both agonist and antagonist binding to diverse G protein-coupled receptors (GPCRs). It blocks the binding of radiolabeled ligands to human opioid, adrenergic, muscarinic, dopaminergic, adenosine, and purinergic receptors. It displays IC50 values of 0.1 to 1.8 µM for modulating...
Schlagworte: | N-(2,3-diphenyl-1,2,4-thiadiazol-5(2H)-ylidene)-methanamine, monohydrobromide |
Anwendung: | GPCR antagonist / agonist binding inhibitor |
CAS | 265980-25-4 |
MW: | 348.3 D |
ab 84,00 €
Artikelnummer: Cay22244-1
Salvinorin B mesylate (Mesyl Sal B) is a selective kappa-opioid receptor agonist that is more potent than salvinorin A (Cay-11487) in CHO cells transfected with the human kappa-opioid receptor (EC50s = 30 and 40 nM, respectively). It is a mesylated version of salvinorin B (Cay-11488) and is highly selective for...
Schlagworte: | Mesyl Sal B,... |
Anwendung: | kappa-opioid receptor agonist |
CAS | 862073-79-8 |
MW: | 468.5 D |
ab 130,00 €
Artikelnummer: Cay22245-1
Salvinorin A carbamate is a potent kappa-opioid receptor (KOR) full agonist that is almost as potent as salvinorin A (Cay-11487) with EC50 values of 6.2 and 4.5 nM, respectively, for activation of the human KOR to enhance binding of [35S]GTPgammaS. The addition of a carbamate group to salvinorin A increases...
Schlagworte: | (2S,4aR,6aR,7R,9S,10aS,10bR)-9-[(aminocarbonyl)oxy]-2-(3-furanyl)dodecahydro-6a,10b-dimethyl-4,10-dioxo-2H-naphtho[2,1-c]p... |
Anwendung: | kappa-opioid receptor agonist |
CAS | 858345-57-0 |
MW: | 433.5 D |
ab 130,00 €