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Zu "K04188" wurden 151 Artikel gefunden!
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Artikelnummer: GSC-M00525
Recombinant CHO-K1 cells stably overexpress human C-X-C motif chemokine receptor 3 (CXCR3) on the surface and contain high levels of G protein Galphai to couple with the receptor in downstream signaling pathways.
| Schlagworte: | CXCR3, CKR-L2, G protein-coupled receptor 9, C-X-C chemokine receptor type 3, Interferon-inducible protein 10 receptor |
11.424,00 €
Artikelnummer: Cay28447-10
SCH 546738 is an antagonist of chemokine (C-X-C motif) receptor 3 (CXCR3, Ki = 0. nM). It is selective for CXCR3 over a panel of 49 other receptors at 10 µM. SCH 546738 (10 or 100 nM) inhibits chemotaxis induced by CXC ligand 9 (CXCL9), CXCL10, or CXCL11 in hemagglutinin- and IL-2-activated primary human T cells. It...
| Schlagworte: | 3-amino-6-chloro-5-[(3S)-4-[1-[(4-chlorophenyl)methyl]-4-piperidinyl]-3-ethyl-1-piperazinyl]-2-pyrazinecarboxamide |
| Anwendung: | CXCR3 antagonist |
| CAS | 906805-42-3 |
| MW: | 492.44 D |
ab 295,00 €
Artikelnummer: Cay28416-1
AMG 487 is a chemokine (C-X-C motif) receptor 3 (CXCR3) antagonist (IC50 = 8.2 nM in a radioligand binding assay). It inhibits cell migration induced by chemokine (C-X-C motif) ligand 10 (CXCL10), CXCL11, and CXCL9 (IC50s = 8, 15, and 36 nM, respectively). In vivo, AMG 487 (3 mg/kg) inhibits bronchoalveolar lavage...
| Schlagworte: | N-[(1R)-1-[3-(4-ethoxyphenyl)-3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-N-(3-pyridinylmethyl)-4-(trifluoromethox... |
| Anwendung: | CXCR3 antagonist |
| CAS | 473719-41-4 |
| MW: | 603.6 D |
ab 85,00 €
Artikelnummer: G-HUFI00746.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
698,00 €
Artikelnummer: G-MOFI00760.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
698,00 €
Artikelnummer: NSJ-R31506
0.5mg/ml if reconstituted with 0.2ml sterile DI water. CXCR3 is a Galphai protein-coupled receptor in the CXC chemokine receptor family. Other names for CXCR3 are G protein-coupled receptor 9 (GPR9) and CD183. CXCR3 is expressed on malignant B cells from chronic lymphoproliferative disorders, particularly in...
| Schlagworte: | Anti-GPR9, Anti-CXCR3, Anti-CD183, Anti-CXC-R3, Anti-CXCR-3, Anti-CKR-L2, Anti-IP-10 receptor, Anti-G protein-coupled... |
| Anwendung: | WB, IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat |
790,00 €
Artikelnummer: NSJ-F40514-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed IP10 (interferon-g-inducible 10 kDa protein), Mig (monokine induced by interferon-g) and I-TAC (interferon-inducible T cell a-chemoattractant). IP10, Mig and I-TAC belong to the...
| Schlagworte: | Anti-GPR9, Anti-CXCR3, Anti-CD183, Anti-CXC-R3, Anti-CXCR-3, Anti-CKR-L2, Anti-IP-10 receptor, Anti-G protein-coupled... |
| Anwendung: | WB, IHC, FC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 361,00 €
Artikelnummer: G-AGEL0430.100
Protein function: Receptor for the C-X-C chemokine CXCL9, CXCL10 and CXCL11 and mediates the proliferation, survival and angiogenic activity of mesangial cells through a heterotrimeric G-protein signaling pathway. Probably promotes cell chemotaxis response. Binds to CCL21. Upon activation by PF4, induces activated...
| Schlagworte: | Anti-Cxcr3, Anti-CD183, Anti-CXC-R3, Anti-Cmkar3, Anti-CXCR-3, Anti-IP-10 receptor, Anti-C-X-C chemokine receptor type 3,... |
| Anwendung: | FC |
| Wirt: | Armenian Hamster |
| Spezies-Reaktivität: | mouse |
ab 88,00 €
Artikelnummer: G-AGEL0431.100
Protein function: Receptor for the C-X-C chemokine CXCL9, CXCL10 and CXCL11 and mediates the proliferation, survival and angiogenic activity of mesangial cells through a heterotrimeric G-protein signaling pathway. Probably promotes cell chemotaxis response. Binds to CCL21. Upon activation by PF4, induces activated...
| Schlagworte: | Anti-Cxcr3, Anti-CD183, Anti-CXC-R3, Anti-Cmkar3, Anti-CXCR-3, Anti-IP-10 receptor, Anti-C-X-C chemokine receptor type 3,... |
| Anwendung: | FC |
| Wirt: | Armenian Hamster |
| Spezies-Reaktivität: | mouse |
ab 88,00 €
Artikelnummer: G-AGEL0432.100
Protein function: Receptor for the C-X-C chemokine CXCL9, CXCL10 and CXCL11 and mediates the proliferation, survival and angiogenic activity of mesangial cells through a heterotrimeric G-protein signaling pathway. Probably promotes cell chemotaxis response. Binds to CCL21. Upon activation by PF4, induces activated...
| Schlagworte: | Anti-Cxcr3, Anti-CD183, Anti-CXC-R3, Anti-Cmkar3, Anti-CXCR-3, Anti-IP-10 receptor, Anti-C-X-C chemokine receptor type 3,... |
| Anwendung: | FC |
| Wirt: | Armenian Hamster |
| Spezies-Reaktivität: | mouse |
ab 132,00 €
Artikelnummer: ARG40317.100
Protein function: Isoform 1: Receptor for the C-X-C chemokine CXCL9, CXCL10 and CXCL11 and mediates the proliferation, survival and angiogenic activity of human mesangial cells (HMC) through a heterotrimeric G-protein signaling pathway (PubMed:12782716). Binds to CCL21. Probably promotes cell chemotaxis response....
| Schlagworte: | Anti-GPR9, Anti-CXCR3, Anti-CD183, Anti-CKR-L2, Anti-CXCR-3, Anti-CXC-R3, Anti-IP-10 receptor, Anti-G protein-coupled... |
| Anwendung: | ICC, IF, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
658,00 €
Artikelnummer: ARG58817.50
Protein function: Isoform 1: Receptor for the C-X-C chemokine CXCL9, CXCL10 and CXCL11 and mediates the proliferation, survival and angiogenic activity of human mesangial cells (HMC) through a heterotrimeric G-protein signaling pathway (PubMed:12782716). Binds to CCL21. Probably promotes cell chemotaxis response....
| Schlagworte: | Anti-GPR9, Anti-CD183, Anti-CXCR3, Anti-CXC-R3, Anti-CXCR-3, Anti-CKR-L2, Anti-IP-10 receptor, Anti-G protein-coupled... |
| Anwendung: | IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat |
551,00 €