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FITC-equivalent Human CCR4 Protein-Nanodisc
FITC-equivalent Human CCR4 Protein-Nanodisc

Artikelnummer: KT-CR4-HM1N122-100UG

Recombinant FITC-equivalent Human CCR4 Protein-Nanodisc is expressed from HEK293 with His tag at the C-terminus.It contains Met1-Leu360. CC chemokine receptor 4 (CCR4) is a chemokine receptor mainly expressed by T cells. CCR4 is important in the pathogenesis of many diseases, such as diabetes, multiple sclerosis,...
Schlagworte: CCR4, K5-5, CD194, CCR-4, CMKBR4, CC-CKR-4, C-C CKR-4, C-C chemokine receptor type 4
Exprimiert in: Human cells
Ursprungsart: human
MW: 69.20 kD
ab 1.530,00 €
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Elab Fluor(R)700 Anti-Human CD194/CCR4 Antibody[L291H4]
Elab Fluor(R)700 Anti-Human CD194/CCR4 Antibody[L291H4]

Artikelnummer: E-AB-F1366M1.100

CD194, also known as CCR4, is a CC chemokine receptor. It binds CCL17 and CCL22 and is expressed on a subset of T and B cells, basophils, monocytes, and NK cells. Human Th2 cells are characterized by the expression of CCR4 and CCR8, and these receptors are regulated differently during Th2 development. Human...
Schlagworte: Anti-CCR4, Anti-K5-5, Anti-CD194, Anti-CCR-4, Anti-CMKBR4, Anti-CC-CKR-4, Anti-C-C CKR-4, Anti-C-C chemokine receptor type...
Anwendung: FC, FCM
Wirt: Mouse
Spezies-Reaktivität: human
ab 132,00 €
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CCR4 Protein, Human, Recombinant (His & SUMO)
CCR4 Protein, Human, Recombinant (His & SUMO)

Artikelnummer: TGM-TMPH-01064-100ug

Description: High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory...
Schlagworte: C-C CKR-4, C-C chemokine receptor type 4, CCR4, CC-CKR-4, K5-5, CCR-4, CMKBR4, CD194
MW: 19.0 kD
ab 236,00 €
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CCR4 Protein-VLP, Human, Recombinant (His)
CCR4 Protein-VLP, Human, Recombinant (His)

Artikelnummer: TGM-TMPH-01065-100ug

Description: High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory...
Schlagworte: CCR-4, C-C chemokine receptor type 4, CD194, CCR4, CC-CKR-4, CMKBR4, C-C CKR-4, K5-5
MW: 43.2 kD
ab 529,00 €
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AZD2098
AZD2098

Artikelnummer: TGM-T4300-100mg

Description: AZD2098 is a potent CC-chemokine receptor 4 (CCR4) inhibitor used for asthma research. Target: CCR. Smiles: COc1nccnc1NS(=O)(=O)c1cccc(Cl)c1Cl. References: Asher Mullard. Cancer charity sees success re-prioritizing industry's shelved compounds. Nature Reviews Drug Discovery 13, 319-321 (2014)
Anwendung: CCR4 antagonist
CAS 566203-88-1
MW: 334.18 D
ab 31,00 €
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Tivumecirnon
Tivumecirnon

Artikelnummer: TGM-T69834-100mg

Description: Tivumecirnon (FLX475) is a potent CCR4 antagonist that effectively inhibits regulatory T cells, which hinder antitumor immune responses, thereby demonstrating significant antitumor activity. Target: Others. Smiles: [C@H](C)(N1C=2C(C(C(F)(F)F)=N1)=NC=C(N2)N3CC(C3)[C@@H]4CN(CCO)CCC4)C5=C(Cl)C=C(Cl)C=C5
Schlagworte: FLX475
Anwendung: Targets C-C chemokine receptor type 4 (CCR4, CD194)
CAS 2174938-78-2
MW: 543.41 D
ab 1.820,00 €
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Anti-CCR4 antibody(DMC297), IgG1 Chimeric mAb
Anti-CCR4 antibody(DMC297), IgG1 Chimeric mAb

Artikelnummer: DIM-DMC100297.10

Protein function: High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating...
Schlagworte: Anti-CC-CKR-4, Anti-CD194, Anti-ChemR13, Anti-CKR4, Anti-CMKBR4, Anti-HGCN:14099, Anti-K5-5, Anti-CCR4 antibody(DMC297),...
Wirt: Rabbit
Spezies-Reaktivität: human
ab 142,00 €
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Human CCR4 Protein, hFc Tag
Human CCR4 Protein, hFc Tag

Artikelnummer: DIM-PME100112.10

Recombinant Human CCR4 with C-terminal human Fc tag. CCR4(Met1-Glu39)(Ala99-Lys111)(Ser176-Val200)(Val268-Tyr284) hFc(Glu99-Ala330), Protein function: High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G(i) proteins which...
Schlagworte: CC-CKR-4, CD194, ChemR13, CKR4, CMKBR4, HGCN:14099, K5-5
Exprimiert in: Human cells
Ursprungsart: human
MW: 37.1 kD
ab 118,00 €
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Human CCR4 (1-39) Protein, hFc Tag
Human CCR4 (1-39) Protein, hFc Tag

Artikelnummer: DIM-PME100824.10

Recombinant Human CCR4 with C-terminal human Fc tag. CCR4(Met1-Glu39) hFc(Glu99-Ala330), Protein function: High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second...
Schlagworte: CC-CKR-4, CD194, ChemR13, CKR4, CMKBR4, HGCN:14099, K5-5
Exprimiert in: Human cells
Ursprungsart: human
CAS 12
MW: 30.6 kD
ab 103,00 €
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Human CCR4(1-39) Protein, mFc Tag
Human CCR4(1-39) Protein, mFc Tag

Artikelnummer: DIM-PME101112.10

Recombinant human CCR4(1-39) protein with C-terminal mouse Fc tag. CCR4(Met1-Glu39) mFc(Pro99-Lys330), Protein function: High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G(i) proteins which activate a...
Schlagworte: CC-CKR-4, CD194, ChemR13, CKR4, CMKBR4, HGCN:14099, K5-5
Exprimiert in: Human cells
Ursprungsart: human
CAS 12
MW: 30.7 kD
ab 148,00 €
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CCR4 (human) full length protein-VLP
CCR4 (human) full length protein-VLP

Artikelnummer: DIM-FLP100015.100

Virus-like particles (VLPs) are self-assembling multi-protein nanoparticles with similar structural organization and conformation as viruses but without viral genome. The size of the VLP is about 100-150nm. It is secreted from the surface of the cells that express target membrane proteins (MPs). The purified VLPs...
Schlagworte: K5-5, CCR4, CD194, CCR-4, CMKBR4, CC-CKR-4, C-C CKR-4, C-C chemokine receptor type 4, CC-CKR-4, CD194, ChemR13, CKR4,...
Anwendung: Full length transmembrane protein, virus-like particle, ELISA, immunization, cell-based assay, screening
Exprimiert in: Human cells
Ursprungsart: human
MW: 41.4 kD
ab 1.721,00 €
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CCR4 (human) full length protein-MNP
CCR4 (human) full length protein-MNP

Artikelnummer: DIM-FLP100016.100

Plasma membrane-coated nanoparticles (MNPs) have been used in various applications, including delivery of therapeutic agents and induction of immune responses et al. Unlike the conventional strategies, MNPs directly leverage intact and natural functions of cell membranes, and show high biocompatibility, specificity,...
Schlagworte: K5-5, CCR4, CD194, CCR-4, CMKBR4, CC-CKR-4, C-C CKR-4, C-C chemokine receptor type 4, CC-CKR-4, CD194, ChemR13, CKR4,...
Anwendung: Full length transmembrane protein, high biocompatib., ELISA, screening, immunization, cell-based assays
Exprimiert in: Human cells
Ursprungsart: human
MW: 41.4 kD
ab 1.721,00 €
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