Zu "K04177" wurden 91 Artikel gefunden!
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NEU
CCR2 Protein-VLP, Human, Recombinant (Flag)
Artikelnummer: TGM-TMPY-07138-100ug
Description: CCR2 Protein-VLP, Human, Recombinant (Flag) is expressed in HEK293 Cells. The accession number is P41597-2.
| Schlagworte: | CCR2A , CC-CKR-2 , CCR2B , CKR2 , PCLUD , FLJ78302 , CCR-2 , CKR2A , MCP-1-R , CKR2B , CD192 , CMKBR2 |
| MW: | 38.82 kD |
ab 260,00 €
Anti-CCR2/CD192 Polyclonal Antibody
Artikelnummer: E-AN100001P.100
The C-C motif chemokine receptor-2 (CCR2) is a G protein-coupled receptor (GPCR), made up of a carboxy-terminus, extracellular amino terminus, and a hydrophobic transmembrane domain consisting of 7 amino acid segments that mediates agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. CCR2 is...
| Schlagworte: | CCR2, CCR-2, CD192, CMKBR2, MCP-1-R, CC-CKR-2, C-C CKR-2, C-C chemokine receptor type 2, Monocyte chemoattractant protein... |
| Anwendung: | WB, ICC/IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
389,00 €
Anti-CCR2/cd192 Polyclonal Antibody
Artikelnummer: E-AN100002P.100
The C-C motif chemokine receptor-2 (CCR2) is a G protein-coupled receptor (GPCR), made up of a carboxy-terminus, extracellular amino terminus, and a hydrophobic transmembrane domain consisting of 7 amino acid segments that mediates agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. CCR2 is...
| Schlagworte: | CCR2, CCR-2, CD192, CMKBR2, MCP-1-R, CC-CKR-2, C-C CKR-2, C-C chemokine receptor type 2, Monocyte chemoattractant protein... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
389,00 €
MK-0812
Artikelnummer: Cay21803-5
MK-0812 is an antagonist of chemokine (C-C) motif receptor 2 (CCR2, IC50 = 5 nM for the human receptor). It inhibits mammosphere formation of BT-549 breast cancer cells, an effect that is enhanced by the beta-catenin inhibitor PNU 74654 (Cay-16349). MK-0812 (0.03, 0.1, and 0.3 mg/kg) increases chemokine (C-C) motif...
| Schlagworte: | 1,5-anhydro-2,3-dideoxy-3-[[(1R,3S)-... |
| Anwendung: | CCR2 antagonist |
| CAS | 624733-88-6 |
| MW: | 469.5 D |
ab 110,00 €
Cenicriviroc
Artikelnummer: TGM-TQ0297-100mg
Description: Cenicriviroc (TAK-652) is an orally active, dual CCR2/CCR5 antagonist that inhibits both HIV-1 and HIV-2, exhibiting potent anti-infective and anti-inflammatory activity. Target: CCR, HIV Protease. Smiles: CCCCOCCOc1ccc(cc1)-c1ccc2N(CC(C)C)CCC\C(=C/c2c1)C(=O)Nc1ccc(cc1)S(=O)Cc1cncn1CCC. References:...
| Schlagworte: | TAK-652, TBR-652 |
| Anwendung: | Targets C-C chemokine receptor type 5 (CCR5, CD195) |
| CAS | 497223-25-3 |
| MW: | 696.94 D |
ab 59,00 €
RS 102895 (hydrochloride)
Artikelnummer: Cay18207-10
The chemokine CCL2, also known as monocyte chemotactic protein-1 (MCP-1), stimulates leukocyte chemotaxis to sites of inflammation via signaling through the MCP-1 receptor, CCR2. RS 102895 is a spiropiperidine compound that acts as a CCR2 antagonist (IC50 = 0.36 µM). It inhibits the related CCR1 receptor with an...
| Schlagworte: | 1'-[2-[4-(trifluoromethyl)phenyl]ethyl]-spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one, monohydrochloride |
| Anwendung: | CCR2 antagonist |
| CAS | 1173022-16-6 |
| MW: | 426.9 D |
ab 52,00 €
INCB 3284 (dimesylate)
Artikelnummer: Cay11963-1
CCR2 is the receptor for the chemokine CCL2, known commonly as monocyte chemotactic protein-1 (MCP-1). INCB 3284 is a potent, selective, and orally bioavailable antagonist of monocyte chemotactic protein-1 binding to CCR2 (IC50 = 3.7 nM). For comparison, it has no significant inhibitor action at over 50 ion...
| Schlagworte: | N-[2-[[(3R)-1-[trans-4-hydroxy-4-(6-methoxy-3-pyridinyl)cyclohexyl]-3-pyrrolidinyl]amino]-2-oxoethyl]-3-(trifluoromethyl)-... |
| Anwendung: | MCP-1 binding antagonist |
| CAS | 887401-93-6 |
| MW: | 712.8 D |
ab 54,00 €
Anti-CD192
Artikelnummer: E-AB-70194.60
This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response...
| Schlagworte: | Anti-CCR2, Anti-CD192, Anti-CCR-2, Anti-CMKBR2, Anti-MCP-1-R, Anti-CC-CKR-2, Anti-C-C CKR-2, Anti-C-C chemokine receptor... |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 195,00 €
BMS 813160
Artikelnummer: Cay28421-1
BMS 813160 is a dual antagonist of chemokine receptor 2 (CCR2) and CCR5 (IC50s = 6.2 and 3.6 nM, respectively, in radioligand binding assays). It inhibits chemotaxis induced by the CCR2 ligand MCP-1 in THP-1 cells the CCR5 ligand MIP-1beta in isolated peripheral T cells with IC50 values of 0.8 and 1.1 nM,...
| Schlagworte: | N-[(1R,2S,5R)-5-[(1,1-dimethylethyl)amino]-2-[(3S)-3-[[7-(1,1-dimethylethyl)pyrazolo[1,5-a]-1,3,5-triazin-4-yl]amino]-2-ox... |
| Anwendung: | CCR2/CCR5 dual antagonist |
| CAS | 1286279-29-5 |
| MW: | 484.6 D |
ab 360,00 €
RS 504393
Artikelnummer: Cay17330-1
RS 504393 is a selective antagonist of the MCP-1 receptor CCR2 (IC50s = 89 nM and >100 µM for CCR2 and CCR1, respectively). It has been shown to inhibit MCP-1-stimulated chemotaxis (IC50 = 330 nM) and ischemia-reperfusion injury in kidneys.Formal Name:...
| Schlagworte: | 6-methyl-1'-[2-(5-methyl-2-phenyl-4-oxazolyl)ethyl]-spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one |
| Anwendung: | CCR2 chemokine receptor antagonist |
| CAS | 300816-15-3 |
| MW: | 417.5 D |
ab 68,00 €
Cenicriviroc
Artikelnummer: Cay23927-1
Cenicriviroc is an orally bioavailable antagonist of C-C chemokine receptor type 5 (CCR5) and CCR2 that inhibits binding of macrophage inflammatory protein 1alpha (MIP-1alpha, IC50 = 2.3 nM) and monocyte chemotactic protein 1 (MCP-1, IC50 = 5.9 nM), respectively, in CHO cells. Cenicriviroc is also an antagonist of...
| Schlagworte: | TAK-652,... |
| Anwendung: | Antiviral, CCR5 / CCR2 antagonist |
| CAS | 497223-25-3 |
| MW: | 696.9 D |
ab 89,00 €
Anti-CCR2
Artikelnummer: NSJ-F52866-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. Receptor for the CCL2, CCL7 and CCL13 chemokines. Transduces a signal by increasing intracellular calcium ion levels. Alternative coreceptor with CD4 for HIV-1 infection. Protein function: Receptor for the CCL2, CCL7 and CCL13 chemokines. Transduces a signal by increasing...
| Schlagworte: | Anti-CCR2, Anti-CCR-2, Anti-CD192, Anti-CMKBR2, Anti-MCP-1-R, Anti-CC-CKR-2, Anti-C-C CKR-2, Anti-C-C chemokine receptor... |
| Anwendung: | WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 361,00 €