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Zu "K04175" wurden 33 Artikel gefunden!
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Artikelnummer: GSC-M00524
Recombinant CHO-K1 cells stably overexpress human C-X-C motif chemokine receptor 1 (CXCR1) on the surface and contain high levels of G protein Galphai and Galphaq to couple with the receptor in downstream signaling pathways.
| Schlagworte: | CXCR1, CDw128a, IL-8 receptor type 1, C-X-C chemokine receptor type 1, High affinity interleukin-8 receptor A |
11.424,00 €
Artikelnummer: ATA-HPA031992.100
Rabbit Polyclonal CXCR1 Antibody against Human C-X-C motif chemokine receptor 1. Validated for Western Blot. Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Interspecies information: Highest antigen sequence indentity to the following orthologs: ENSMUSG00000026180: 60%,...
| Schlagworte: | Anti-CXCR1, Anti-CD181, Anti-CXCR-1, Anti-CMKAR1, Anti-CXC-R1, Anti-CDw128a, Anti-IL-8R A, Anti-IL-8 receptor type 1,... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
463,00 €
Artikelnummer: Cay21492-10
Reparixin is a non-competitive allosteric inhibitor of the activation of CXCR1 and CXCR2 chemokine receptors by IL-8 (IC50s = 1 and 100 nM, respectively). It blocks a range of activities related to IL-8 signaling, including leukocyte recruitment (IC50 = 1 nM) and other inflammatory responses, without affecting...
| Schlagworte: | Repertaxin, (alphaR)-alpha-methyl-4-(2-methylpropyl)-N-(methylsulfonyl)benzeneacetamide, L-lysine |
| Anwendung: | Noncompetitive allosteric CXCR1 / CXCR2 inhibitor |
| CAS | 266359-93-7 |
| MW: | 429.6 D |
ab 40,00 €
Artikelnummer: G-HUFI00504.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
698,00 €
Artikelnummer: NSJ-R31191
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Chemokine CXC Motif Receptor 1, also known as IL8R, is the receptor for IL8. Morris et al.(1992) mapped the gene to chromosome 2q35. Hartl et al.(2007) concluded that CXCR1 cleavage and its functional consequences represent an important pathophysiologic...
| Schlagworte: | Anti-CXCR1, Anti-CD181, Anti-CXC-R1, Anti-CXCR-1, Anti-CMKAR1, Anti-IL-8R A, Anti-CDw128a, Anti-IL-8 receptor type 1,... |
| Anwendung: | WB, FC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
790,00 €
Artikelnummer: ARG11053.50
Protein function: Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high...
| Schlagworte: | Anti-CD181, Anti-CXCR1, Anti-CXC-R1, Anti-CXCR-1, Anti-CMKAR1, Anti-CDw128a, Anti-IL-8R A, Anti-IL-8 receptor type 1,... |
| Anwendung: | IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
559,00 €
Artikelnummer: Cay27800-1
SCH 527123 is an allosteric antagonist of C-X-C chemokine receptor type 1 (CXCR1, IC50 = 43 nM in Ba/F3 cells) and CXCR2 (IC50 = 0.97 nM in HTS cells). It inhibits calcium flux induced by CXCL8 in Ba/F3 cells expressing human recombinant CXCR1 or CXCR2. SCH 527123 (3 nM) inhibits CXCL8-induced chemotaxis of Ba/F3...
| Schlagworte: | MK-7123, 2-hydroxy-N,N-dimethyl-3-[[2-[[(1R)-1-(5-methyl-2-furanyl)propyl]amino]-3,4-dioxo-1-cyclobuten-1-yl]amino]-benzamide |
| Anwendung: | Allosteric CXCR1 antagonist |
| CAS | 473727-83-2 |
| MW: | 397.4 D |
ab 38,00 €
Artikelnummer: G-HUES01984.96
ELISA Type: Sandwich. Sensitivity: 0.188ng/mL. Range: 0.313--20ng/mL. Protein function: Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a...
| Schlagworte: | CD181, CXCR1, CXC-R1, CXCR-1, CMKAR1, IL-8R A, CDw128a, IL-8 receptor type 1, C-X-C chemokine receptor type 1, High... |
| Anwendung: | Sandwich ELISA |
| Spezies-Reaktivität: | human |
708,00 €
Artikelnummer: ATA-HPA031991.100
Protein function: Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high...
| Schlagworte: | Anti-CD181, Anti-CXCR1, Anti-CXCR-1, Anti-CXC-R1, Anti-CMKAR1, Anti-CDw128a, Anti-IL-8R A, Anti-IL-8 receptor type 1,... |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 330,00 €
Artikelnummer: DIM-DMC100470.10
Protein function: Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high...
| Schlagworte: | Anti-C-C, Anti-C-C-CKR-1, Anti-CD128, Anti-CD181, Anti-CDw128a, Anti-CKR-1, Anti-CMKAR1, Anti-IL8R1, Anti-IL8RA,... |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 145,00 €
Artikelnummer: DIM-PME100820.10
Recombinant human CXCR1 protein with C-terminal human Fc tag. CXCR1(Met1-Lys39) hFc(Glu99-Ala330), Protein function: Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate...
| Schlagworte: | C-C, C-C-CKR-1, CD128, CD181, CDw128a, CKR-1, CMKAR1, IL8R1, IL8RA, IL8RBA |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 30.6 kD |
ab 151,00 €
Artikelnummer: DIM-FLP100091.10
Discover a breakthrough in membrane protein research and drug development with DIMA Biotech's Synthetic Nanodiscs. Traditional methods struggle with challenges in obtaining water-soluble and bioactive forms of multi-transmembrane proteins. Our innovative polymer-based Nanodisc platform offers a game-changing...
| Schlagworte: | CXCR1, CD181, CMKAR1, CXC-R1, CXCR-1, CDw128a, IL-8R A, IL-8 receptor type 1, C-X-C chemokine receptor type 1, High... |
| Anwendung: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 39.8 kD |
ab 1.317,00 €