Zu "K04175" wurden 23 Artikel gefunden!
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Reparixin
Artikelnummer: Cay17350-1
Reparixin is an allosteric antagonist of chemokine (C-X-C motif) receptor 1 (CXCR1) and CXCR2 (IC50s = 1 and 100 nM, respectively). In vivo, reparixin (3, 15, and 30 mg/kg) reduces ischemia and reperfusion-induced hepatic polymorphonuclear leukocyte (PMN) recruitment, hepatic myeloperoxidase (MPO) levels, and serum...
| Schlagworte: | DF 1681Y, Repertaxin, (alphaR)-alpha-methyl-4-(2-methylpropyl)-N-(methylsulfonyl)-benzeneacetamide |
| Anwendung: | Allosteric CXCR1 / CXCR2 antagonist |
| CAS | 266359-83-5 |
| MW: | 283.4 D |
ab 35,00 €
Reparixin (L-Lysine salt)
Artikelnummer: Cay21492-10
Reparixin is a non-competitive allosteric inhibitor of the activation of CXCR1 and CXCR2 chemokine receptors by IL-8 (IC50s = 1 and 100 nM, respectively). It blocks a range of activities related to IL-8 signaling, including leukocyte recruitment (IC50 = 1 nM) and other inflammatory responses, without affecting...
| Schlagworte: | Repertaxin, (alphaR)-alpha-methyl-4-(2-methylpropyl)-N-(methylsulfonyl)benzeneacetamide, L-lysine |
| Anwendung: | Noncompetitive allosteric CXCR1 / CXCR2 inhibitor |
| CAS | 266359-93-7 |
| MW: | 429.6 D |
ab 35,00 €
Human CXCR1 / IL-8 receptor alpha ELISA Kit
Artikelnummer: G-HUFI00504.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
641,00 €
Anti-CXCR1
Artikelnummer: NSJ-R31191
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Chemokine CXC Motif Receptor 1, also known as IL8R, is the receptor for IL8. Morris et al.(1992) mapped the gene to chromosome 2q35. Hartl et al.(2007) concluded that CXCR1 cleavage and its functional consequences represent an important pathophysiologic...
| Schlagworte: | Anti-CXCR1, Anti-CD181, Anti-CXC-R1, Anti-CXCR-1, Anti-CMKAR1, Anti-IL-8R A, Anti-CDw128a, Anti-IL-8 receptor type 1,... |
| Anwendung: | WB, FC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
755,00 €
Anti-CXCR1
Artikelnummer: NSJ-R33687-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Chemokine (C-X-C motif) receptor 1 Protein function: Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of...
| Schlagworte: | Anti-CD181, Anti-CXCR1, Anti-CXCR-1, Anti-CXC-R1, Anti-CMKAR1, Anti-CDw128a, Anti-IL-8R A, Anti-IL-8 receptor type 1,... |
| Anwendung: | WB, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
755,00 €
Anti-CXCR1
Artikelnummer: ARG11053.50
Protein function: Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high...
| Schlagworte: | Anti-CD181, Anti-CXCR1, Anti-CXC-R1, Anti-CXCR-1, Anti-CMKAR1, Anti-CDw128a, Anti-IL-8R A, Anti-IL-8 receptor type 1,... |
| Anwendung: | IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
528,00 €
SCH 527123
Artikelnummer: Cay27800-1
SCH 527123 is an allosteric antagonist of C-X-C chemokine receptor type 1 (CXCR1, IC50 = 43 nM in Ba/F3 cells) and CXCR2 (IC50 = 0.97 nM in HTS cells). It inhibits calcium flux induced by CXCL8 in Ba/F3 cells expressing human recombinant CXCR1 or CXCR2. SCH 527123 (3 nM) inhibits CXCL8-induced chemotaxis of Ba/F3...
| Schlagworte: | MK-7123, 2-hydroxy-N,N-dimethyl-3-[[2-[[(1R)-1-(5-methyl-2-furanyl)propyl]amino]-3,4-dioxo-1-cyclobuten-1-yl]amino]-benzamide |
| Anwendung: | Allosteric CXCR1 antagonist |
| CAS | 473727-83-2 |
| MW: | 397.4 D |
ab 76,00 €
Human CXCR1 (CXC-Chemokine Receptor 1) ELISA Kit
Artikelnummer: G-HUES01984.96
ELISA Type: Sandwich. Sensitivity: 0.188ng/mL. Range: 0.313--20ng/mL. Protein function: Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a...
| Schlagworte: | CD181, CXCR1, CXC-R1, CXCR-1, CMKAR1, IL-8R A, CDw128a, IL-8 receptor type 1, C-X-C chemokine receptor type 1, High... |
| Anwendung: | Sandwich ELISA |
| Spezies-Reaktivität: | human |
641,00 €
Anti-CXCR1
Artikelnummer: E-AB-66790.120
The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits...
| Schlagworte: | Anti-CXCR1, Anti-CD181, Anti-CXCR-1, Anti-CXC-R1, Anti-CMKAR1, Anti-IL-8R A, Anti-CDw128a, Anti-IL-8 receptor type 1,... |
| Anwendung: | WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 198,00 €
Anti-CXCR1
Artikelnummer: G-CAB16386.100
WB 1:500 - 1:2000. Protein function: Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to...
| Schlagworte: | Anti-CXCR1, Anti-CD181, Anti-CXCR-1, Anti-CXC-R1, Anti-CMKAR1, Anti-CDw128a, Anti-IL-8R A, Anti-IL-8 receptor type 1,... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | rat |
ab 352,00 €
Anti-CXCR1
Artikelnummer: ATA-HPA031991.100
Protein function: Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high...
| Schlagworte: | Anti-CD181, Anti-CXCR1, Anti-CXCR-1, Anti-CXC-R1, Anti-CMKAR1, Anti-CDw128a, Anti-IL-8R A, Anti-IL-8 receptor type 1,... |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 300,00 €
Anti-IL-8RA
Artikelnummer: ELK-ES8797.100
C-X-C motif chemokine receptor 1(CXCR1) Homo sapiens The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system....
| Schlagworte: | Anti-CD181, Anti-CXCR1, Anti-CMKAR1, Anti-CXC-R1, Anti-CXCR-1, Anti-CDw128a, Anti-IL-8R A, Anti-IL-8 receptor type 1,... |
| Anwendung: | WB, IHC, IF, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 169,00 €