Zu "K04175" wurden 31 Artikel gefunden!
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Reparixin
Artikelnummer: TGM-T4163-100mg
Description: Reparixin (Repertaxin) is a potent inhibitor of both CXCL8 receptors CXCR1/2, it inhibits weakly CXCR2-mediated cell migration (IC50=100 nM), whereas it strongly blocks CXCR1-mediated chemotaxis (IC50=1 nM). Target: CXCR. Smiles: CC(C)Cc1ccc(cc1)[C@@H](C)C(=O)NS(C)(=O)=O. References: Moriconi A, et al....
| Schlagworte: | DF 1681Y, Repertaxin |
| Anwendung: | Targets C-X-C chemokine receptor type 1 (CXCR1, IL8RA, CD181) |
| CAS | 266359-83-5 |
| MW: | 283.39 D |
ab 48,00 €
Navarixin
Artikelnummer: TGM-T7130-100mg
Description: Navarixin (MK-7123)(SCH527123) is a novel, selective CXC chemokine receptor 2(CXCR2) antagonist that inhibits neutrophil activation and modulates neutrophil trafficking in animal models, characteristics that may be beneficial in the treatment of conditions with unbalanced pulmonary neutrophilia. Target:...
| Schlagworte: | MK-7123, SCH 527123 |
| Anwendung: | Allosteric CXCR1 antagonist |
| CAS | 473727-83-2 |
| MW: | 397.42 D |
ab 34,00 €
Anti-CXCR1 antibody(DMC470), IgG1 Chimeric mAb
Artikelnummer: DIM-DMC100470.10
Protein function: Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high...
| Schlagworte: | Anti-C-C, Anti-C-C-CKR-1, Anti-CD128, Anti-CD181, Anti-CDw128a, Anti-CKR-1, Anti-CMKAR1, Anti-IL8R1, Anti-IL8RA,... |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 142,00 €
Human CXCR1 Protein, hFc Tag
Artikelnummer: DIM-PME100820.10
Recombinant human CXCR1 protein with C-terminal human Fc tag. CXCR1(Met1-Lys39) hFc(Glu99-Ala330), Protein function: Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate...
| Schlagworte: | C-C, C-C-CKR-1, CD128, CD181, CDw128a, CKR-1, CMKAR1, IL8R1, IL8RA, IL8RBA |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 30.6 kD |
ab 148,00 €
CXCR1 (human) full length protein-synthetic nanodisc
Artikelnummer: DIM-FLP100091.10
Discover a breakthrough in membrane protein research and drug development with DIMA Biotech's Synthetic Nanodiscs. Traditional methods struggle with challenges in obtaining water-soluble and bioactive forms of multi-transmembrane proteins. Our innovative polymer-based Nanodisc platform offers a game-changing...
| Schlagworte: | CXCR1, CD181, CMKAR1, CXC-R1, CXCR-1, CDw128a, IL-8R A, IL-8 receptor type 1, C-X-C chemokine receptor type 1, High... |
| Anwendung: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 39.8 kD |
ab 1.291,00 €
Anti-CXCR1
Artikelnummer: CSB-PA239685.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: CXCR1. Antigen Species: Human
| Schlagworte: | Anti-CXCR1, Anti-CD181, Anti-CXCR-1, Anti-CXC-R1, Anti-CMKAR1, Anti-CDw128a, Anti-IL-8R A, Anti-IL-8 receptor type 1,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 167,00 €
Anti-CXCR1
Artikelnummer: CSB-PA821914.50
Host Species: Rabbit. Isotype: IgG. Buffer: PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific...
| Schlagworte: | Anti-CXCR1, Anti-CD181, Anti-CXCR-1, Anti-CXC-R1, Anti-CMKAR1, Anti-CDw128a, Anti-IL-8R A, Anti-IL-8 receptor type 1,... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
126,00 €
Reparixin
Artikelnummer: Cay17350-1
Reparixin is an allosteric antagonist of chemokine (C-X-C motif) receptor 1 (CXCR1) and CXCR2 (IC50s = 1 and 100 nM, respectively). In vivo, reparixin (3, 15, and 30 mg/kg) reduces ischemia and reperfusion-induced hepatic polymorphonuclear leukocyte (PMN) recruitment, hepatic myeloperoxidase (MPO) levels, and serum...
| Schlagworte: | DF 1681Y, Repertaxin, (alphaR)-alpha-methyl-4-(2-methylpropyl)-N-(methylsulfonyl)-benzeneacetamide |
| Anwendung: | Allosteric CXCR1 / CXCR2 antagonist |
| CAS | 266359-83-5 |
| MW: | 283.4 D |
ab 36,00 €
Reparixin (L-Lysine salt)
Artikelnummer: Cay21492-10
Reparixin is a non-competitive allosteric inhibitor of the activation of CXCR1 and CXCR2 chemokine receptors by IL-8 (IC50s = 1 and 100 nM, respectively). It blocks a range of activities related to IL-8 signaling, including leukocyte recruitment (IC50 = 1 nM) and other inflammatory responses, without affecting...
| Schlagworte: | Repertaxin, (alphaR)-alpha-methyl-4-(2-methylpropyl)-N-(methylsulfonyl)benzeneacetamide, L-lysine |
| Anwendung: | Noncompetitive allosteric CXCR1 / CXCR2 inhibitor |
| CAS | 266359-93-7 |
| MW: | 429.6 D |
ab 36,00 €
Human CXCR1 / IL-8 receptor alpha ELISA Kit
Artikelnummer: G-HUFI00504.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
641,00 €
Anti-CXCR1
Artikelnummer: NSJ-R31191
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Chemokine CXC Motif Receptor 1, also known as IL8R, is the receptor for IL8. Morris et al.(1992) mapped the gene to chromosome 2q35. Hartl et al.(2007) concluded that CXCR1 cleavage and its functional consequences represent an important pathophysiologic...
| Schlagworte: | Anti-CXCR1, Anti-CD181, Anti-CXC-R1, Anti-CXCR-1, Anti-CMKAR1, Anti-IL-8R A, Anti-CDw128a, Anti-IL-8 receptor type 1,... |
| Anwendung: | WB, FC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
772,00 €
Anti-CXCR1
Artikelnummer: ARG11053.50
Protein function: Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high...
| Schlagworte: | Anti-CD181, Anti-CXCR1, Anti-CXC-R1, Anti-CXCR-1, Anti-CMKAR1, Anti-CDw128a, Anti-IL-8R A, Anti-IL-8 receptor type 1,... |
| Anwendung: | IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
559,00 €