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Zu "K04174" wurden 24 Artikel gefunden!
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Artikelnummer: ELK-ELK6314.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat APLNR. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat APLNR. Next,...
Schlagworte: | B78, Aplnr, Agtrl1, GPCR34, Apelin receptor, Angiotensin receptor-like 1, G-protein coupled receptor APJ |
Anwendung: | ELISA |
Spezies-Reaktivität: | rat |
ab 365,00 €
Artikelnummer: ELK-ELK8782.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human APLNR. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human APLNR. Next,...
Schlagworte: | APLNR, AGTRL1, Apelin receptor, Angiotensin receptor-like 1, G-protein coupled receptor APJ, G-protein coupled receptor HG11 |
Anwendung: | ELISA |
Spezies-Reaktivität: | human |
ab 365,00 €
Artikelnummer: Cay15590-1
The apelin gene encodes a pre-proprotein that is processed to generate bioactive peptides consisting of 36, 17, or 13 amino acids: apelin-36 (Cay-13524), apelin-17, and apelin-13 (Cay-13523), respectively. Apelin-13 is an endogenous ligand of the APJ receptor, activating this G protein-coupled receptor with an EC50...
Schlagworte: | (pGlu1)Apelin-13, (Pyr1)Apelin-13, Pyr-Apelin-13,... |
Anwendung: | APLNR / APJ receptor ligand |
MW: | 1533.8 D |
211,00 €
Artikelnummer: Cay13523-25
The apelin gene encodes a pre-proprotein that is processed to generate bioactive peptides consisting of 36, 17, or 13 amino acids (apelin-36, apelin-17, and apelin-13, respectively). Apelin-13 is the endogenous ligand of the APJ receptor, activating this G protein-coupled receptor with an EC50 value of 0.37 nM (the...
Schlagworte: | L-glutaminyl-L-arginyl-L-prolyl-L-arginyl-L-leucyl-L-seryl-L-histidyl-L-lysylglycyl-L-prolyl-L-methionyl-L-prolyl-L-phenyl... |
Anwendung: | APJ receptor ligand |
MW: | 1550.8 D |
ab 77,00 €
Artikelnummer: Cay15187-1
The apelin receptor (APJ) signaling pathway mediates cardiovascular homeostasis and is involved in the pathogenesis of cardiovascular diseases. ML-233 is a novel APJ agonist (EC50 = 3.7 µM) that is >21-fold selective over the closely related angiotensin 1 receptor (EC50 = >79 µM).Formal Name:...
Schlagworte: | CID-46905036, (E)-4-methyl-5-(((phenylsulfonyl)oxy)imino)-[1,1'-bi(cyclohexane)]-3,6-dien-2-one |
Anwendung: | APLNR agonist |
MW: | 359.4 D |
ab 61,00 €
Artikelnummer: Cay27313-5
ML-221 is an antagonist of the G protein-coupled receptor (GPCR) APJ (IC50 = 4.8 µM). It is selective for APJ over the angiotensin II type 1 (AT1) receptor (IC50 = >78 µM). ML-221 antagonizes apelin 13-induced activation of APJ in cAMP and beta-arrestin recruitment assays (IC50s = 0.7 and 1.75 µM, respectively). It...
Schlagworte: | 5-[(4-nitrobenzoyl)oxy]-2-[(2-pyrimidinylthio)methyl]-4H-pyran-4-one |
Anwendung: | Apelin receptor (APJ) antagonist |
CAS | 877636-42-5 |
MW: | 385.4 D |
ab 88,00 €
Artikelnummer: E-AB-13919.120
This gene encodes a member of the G protein-coupled receptor gene family. The encoded protein is related to the angiotensin receptor, but is actually an apelin receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive...
Schlagworte: | Anti-APLNR, Anti-AGTRL1, Anti-Apelin receptor, Anti-Angiotensin receptor-like 1, Anti-G-protein coupled receptor APJ,... |
Anwendung: | IHC, ELISA |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
ab 71,00 €
Artikelnummer: E-AB-10156.120
This gene encodes a member of the G protein-coupled receptor gene family. The encoded protein is related to the angiotensin receptor, but is actually an apelin receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive...
Schlagworte: | Anti-APLNR, Anti-AGTRL1, Anti-Apelin receptor, Anti-Angiotensin receptor-like 1, Anti-G-protein coupled receptor APJ,... |
Anwendung: | IHC, ELISA |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
ab 71,00 €
Artikelnummer: ARG40385.100
Protein function: Receptor for apelin receptor early endogenous ligand (APELA) and apelin (APLN) hormones coupled to G proteins that inhibit adenylate cyclase activity (PubMed:11090199, PubMed:25639753, PubMed:28137936). Plays a key role in early development such as gastrulation, blood vessels formation and heart...
Schlagworte: | Anti-APLNR, Anti-AGTRL1, Anti-Apelin receptor, Anti-Angiotensin receptor-like 1, Anti-G-protein coupled receptor APJ,... |
Anwendung: | WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
624,00 €
Artikelnummer: G-CAB2659.100
Anwendung: | IHC, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
ab 352,00 €
Artikelnummer: ELK-ES5037.100
This gene encodes a member of the G protein-coupled receptor gene family. The encoded protein is related to the angiotensin receptor, but is actually an apelin receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive...
Schlagworte: | Anti-APLNR, Anti-AGTRL1, Anti-Apelin receptor, Anti-Angiotensin receptor-like 1, Anti-G-protein coupled receptor APJ,... |
Anwendung: | WB, IHC, IF, ELISA |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, rat, mouse, |
ab 169,00 €
Artikelnummer: Cay13524-1
The apelin gene encodes a preproprotein that is processed to generate a variety of bioactive peptides, including those having 36, 17, or 13 amino acids (apelin-36, apelin-17, and apelin-13, respectively). The apelin proteins are the endogenous ligands of the G protein-coupled receptor, APJ. Apelin-36 is the...
Anwendung: | APJ agonist |
CAS | 252642-12-9 |
MW: | 4195.9 D |
ab 267,00 €