Zu "K04160" wurden 58 Artikel gefunden!
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Naronapride
Artikelnummer: TGM-T63785-100mg
Description: Naronapride (ATI-7505) is a potent 5-HT4 receptor agonist, useful for studying gastrointestinal disorders. Target: Others. Smiles: C(N[C@H]1[C@@H](OC)CN(CCCCCC(O[C@@H]2C3CCN(C2)CC3)=O)CC1)(=O)C4=C(OC)C=C(N)C(Cl)=C4
| Anwendung: | Targets 5-hydroxytryptamine receptor 4 (HTR4) |
| CAS | 860174-12-5 |
| MW: | 537.09 D |
ab 2.142,00 €
PF-04995274
Artikelnummer: TGM-T16481-100mg
Description: PF-04995274 is an effective, high-affinity, and partial serotonin 4 receptor (5-HT4R) agonist. PF-04995274 is brain penetrant and can be used for cognitive disorders associated with Alzheimer's disease. PF-04995274 has an EC50 range of 0.26-0.47 nM for human 5-HT4A/4B/4D/4E (Ki range of 0.15-0.46 nM)....
| Anwendung: | 5-HT4A / 5-HT4B / 5-HT4D / 5-HT4E partial agonist |
| CAS | 1331782-27-4 |
| MW: | 432.51 D |
ab 31,00 €
Tegaserod maleate
Artikelnummer: TGM-T1551-100mg
Description: Tegaserod maleate (SDZ-HTF-919) is a 5-HT4 agonist manufactured by Novartis for managing irritable bowel syndrome and constipation. It was the only drug approved by the United States Food and Drug Administration for relieving abdominal discomfort, bloating, and constipation associated with irritable...
| Schlagworte: | HTF-919, SDZ-HTF-919 |
| Anwendung: | Targets 5-hydroxytryptamine receptor 4 (HTR4) |
| CAS | 189188-57-6 |
| MW: | 417.46 D |
ab 40,00 €
Velusetrag
Artikelnummer: TGM-T35046-100mg
Description: Velusetrag(TD-5108)is an effective, selective, and highly potent agonist of the 5-HT4 receptor, and being developed for the treatment of gastroparesis, chronic constipation, and irritable bowel syndrome. Target: Others. Smiles:...
| Schlagworte: | TD5108, TD 5108, TD-5108 |
| Anwendung: | Targets 5-hydroxytryptamine receptor 4 (HTR4) |
| CAS | 866933-46-2 |
| MW: | 504.64 D |
ab 1.140,00 €
Relenopride hydrochloride
Artikelnummer: TGM-T28512-100mg
Description: Relenopride, a 5-HT agonist, is used potentially for the treatment of chronic constipation. Target: Others. Smiles: Cl.COc1cc(N)c(Cl)cc1C(=O)NCC1CCN(CC[C@H](OC(N)=O)c2ccc(F)cc2)CC1. References: Nusrat S, Miner PB Jr. New pharmacological treatment options for irritable bowel syndrome with constipation....
| Schlagworte: | YKP-10811, YKP10811, YKP 10811, Relenopride HCl |
| Anwendung: | Targets 5-hydroxytryptamine receptor 4 (HTR4) |
| CAS | 1221416-42-7 |
| MW: | 529.43 D |
ab 916,00 €
Felcisetrag
Artikelnummer: TGM-T28934-100mg
Description: Felcisetrag (TD-8954) is a potent and selective orally active 5-HT4 agonist with gastrointestinal prokinetic properties.Felcisetrag shows high affinity for the human recombinant 5-HT4(c) (h5-HT4(c)) receptor with a pKi of 9.4. Target: 5-HT Receptor. Smiles:...
| Schlagworte: | TD-8954, TD 8954, TD8954 |
| Anwendung: | Targets 5-hydroxytryptamine receptor 4 (HTR4) |
| CAS | 916075-84-8 |
| MW: | 455.59 D |
ab 156,00 €
Naronapride dihydrochloride
Artikelnummer: TGM-T33597-100mg
Description: Naronapride dihydrochloride is used in the Treatment of Gastric Disorder. Target: Others. Smiles: CO[C@@H](CN(CC1)CCCCCC(O[C@@H]2C3CCN(CC3)C2)=O)[C@@H]1NC(C4=C(C=C(C(Cl)=C4)N)OC)=O.Cl.Cl. References: Bowersox SS, Lightning LK, Rao S, Palme M, Ellis D, Coleman R, Davies AM, Kumaraswamy P, Druzgala P....
| Anwendung: | Targets 5-hydroxytryptamine receptor 4 (HTR4) |
| CAS | 860169-57-9 |
| MW: | 610.01 D |
ab 6.998,00 €
Renzapride
Artikelnummer: TGM-T38507-100mg
Description: Renzapride (BRL 24924) is a mixed 5-hydroxytryptamine type 4 (5-HT4) agonist and 5-HT3 receptor antagonist.Renzapride can be used in the study of constipation-predominant irritable bowel syndrome (C-IBS). Target: 5-HT Receptor. Smiles: COc1cc(N)c(Cl)cc1C(=O)N[C@H]1CCN2CCC[C@@H]1C2. References: Meyers...
| Schlagworte: | BRL 24924 |
| Anwendung: | Targets 5-hydroxytryptamine receptor 4 (HTR4) |
| CAS | 112727-80-7 |
| MW: | 323.82 D |
ab 147,00 €
Tegaserod
Artikelnummer: TGM-T60680-2mg
Description: Tegaserod is an orally available 5-HT4R agonist and 5-HT2B receptor antagonist with inhibitory effects on various 5-hydroxytryptamine receptors. Tegaserod has antitumor activity and is used in the treatment of irritable bowel syndrome (IBS). Target: 5-HT Receptor. Smiles:...
| Anwendung: | Targets 5-hydroxytryptamine receptor 4 (HTR4) |
| CAS | 145158-71-0 |
| MW: | 301.39 D |
31,00 €
Usmarapride
Artikelnummer: TGM-T63069-100mg
Description: Usmarapride (SUVN-D4010) is a selective, orally active, potent 5-HT4 receptor partial agonist with blood-brain barrier permeability and an EC50 value of 44 nM, used to study cognitive deficits associated with Alzheimer's disease. Target: Others. Smiles:...
| Anwendung: | 5-HT4 partial agonist |
| CAS | 1428862-33-2 |
| MW: | 473.53 D |
ab 1.200,00 €
Mosapride Citrate
Artikelnummer: TGM-T6597-100mg
Description: Mosapride Citrate (TAK-370 citrate), a gastroprokinetic agent, utilizes as a selective 5HT4 agonist. Target: 5-HT Receptor. Smiles: OC(=O)CC(O)(CC(O)=O)C(O)=O.CCOc1cc(N)c(Cl)cc1C(=O)NCC1CN(Cc2ccc(F)cc2)CCO1. References: Nonogaki K, Kaji T. Diabetes Res Clin Pract. 2015 Dec,110(3):e18-21.
| Schlagworte: | AS-4370, TAK-370 citrate, AS-4370 citrate |
| Anwendung: | Serotonin receptor subtype 5-HT4 agonist |
| CAS | 112885-42-4 |
| MW: | 614.02 D |
ab 43,00 €
Mosapride citrate dihydrate
Artikelnummer: TGM-T6597L-5mg
Description: Mosapride Citrate is a 5-HT4 receptor agonist used to stimulate gastrointestinal motility via acetylcholine. Mosapride Citrate facilitates acetylcholine release from the enteric cholinergic neurons. Target: Others. Smiles: O.OC(=O)CC(O)(CC(O)=O)C(O)=O.CCOc1cc(N)c(Cl)cc1C(=O)NCC1CN(Cc2ccc(F)cc2)CCO1....
| Schlagworte: | Mosapride Citrate, GR-107719-B, GR 107719 B, AS 4370, TAK-370, AS-4370 |
| Anwendung: | Targets 5-hydroxytryptamine receptor 4 (HTR4) |
| CAS | 636582-62-2 |
| MW: | 632.04 D |
98,00 €