Zu "K04157" wurden 260 Artikel gefunden!
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(+)-Fenfluramine (hydrochloride)
Artikelnummer: Cay39830-25
(+)-Fenfluramine is an agonist of the serotonin (5-HT) receptor subtypes 5-HT2B and 5-HT2C. It induces serotonin release from superfused midbrain synaptosome preparations isolated from wild-type mice, but not 5-HT2B-/- mice, when used at concentrations of 0. or 1 µM. (+)-Fenfluramine (3 or 10 mg/kg) reduces food...
| Schlagworte: | Dexfenfluramine, N-ethyl-alpha-methyl-3-(trifluoromethyl)-benzeneethanamine, monohydrochloride |
| Anwendung: | 5-HT2B / 5-HT2C receptor agonist |
| CAS | 3239-45-0 |
| MW: | 267.7 D |
ab 91,00 €
CHO-K1/5-HT2A Stable Cell Line
Artikelnummer: GSC-M00251
Recombinant CHO-K1 cells stably overexpress human 5-hydroxytryptamine receptor 2A (5-HT2A) on the surface and contain high levels of G protein Galphaq and Galphai to couple with the receptor in downstream signaling pathways.
| Schlagworte: | HTR2A, Serotonin receptor 2A, 5-hydroxytryptamine receptor 2A |
11.424,00 €
HEK293/5-HT2C Stable Cell Line
Artikelnummer: GSC-M00319
Recombinant HEK293 cells stably overexpress human 5-hydroxytryptamine receptor 2C (5-HT2C) on the surface and contain high level of G protein Galphai and Galphaq to couple with the receptor in downstream signaling pathways.
| Schlagworte: | HTR2C, Serotonin receptor 2C, 5-hydroxytryptamine receptor 1C, 5-hydroxytryptamine receptor 2C |
11.424,00 €
CHO-K1/5-HT2C Stable Cell Line
Artikelnummer: GSC-M00253
5-Hydroxytryptamine (5-HT, also commonly known as serotonin) is synthesized in enterochromaffin cells in the intestine and in serotonergic nerve terminals. In the periphery, 5-HT mediates gastrointestinal motility, platelet aggregation, and contraction of blood vessels. Many functions of the central nervous system...
| Schlagworte: | HTR2C, Serotonin receptor 2C, 5-hydroxytryptamine receptor 1C, 5-hydroxytryptamine receptor 2C |
11.424,00 €
CHO-K1/5-HT2B Stable Cell Line
Artikelnummer: GSC-M00249
5-Hydroxytryptamine (5-HT, also commonly known as serotonin) is synthesized in enterochromaffin cells in the intestine and in serotonergic nerve terminals. In the periphery, 5-HT mediates gastrointestinal motility, platelet aggregation, and contraction of blood vessels. Many functions of the central nervous system...
| Schlagworte: | HTR2B, Serotonin receptor 2B, 5-hydroxytryptamine receptor 2B |
11.424,00 €
Clozapine N-oxide
Artikelnummer: LKT-C4759.25
Metabolite of clozapine. It is 5-HT2 serotonin receptor antagonist.
| Anwendung: | 5-HT2 serotonin receptor antagonist |
| CAS | 34233-69-7 |
| MW: | 342,82 D |
ab 274,00 €
Serotonin-d4 (hydrochloride)
Artikelnummer: Cay29415-1
Serotonin-d4 is intended for use as an internal standard for the quantification of serotonin (Cay-14332) by GC- or LC-MS. Serotonin is a monoamine neurotransmitter that is biochemically derived from tryptophan and produced in serotonergic neurons in the central nervous system and in enterochromaffin cells in the...
| Schlagworte: | 5-HT-d4, 5-Hydroxytryptamine-d4, 3-(2-aminoethyl-1,1,2,2-d4)-1H-indol-5-ol, monohydrochloride |
| Anwendung: | GC-MS, LC-MS, internal standard, monoamine neurotransmitter |
| CAS | 2469263-61-2 |
| MW: | 216.7 D |
ab 170,00 €
Lorcaserin (hydrochloride)
Artikelnummer: Cay42461-10
An analytical reference standard categorized as an anorectic, decreases oxycodone intake and has positive effects on self-administration and relapse vulnerability in rats, regulated as a Schedule IV compound in the United States, intended for research and forensic applications
| Schlagworte: | APD356, 8-chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine, monohydrochloride |
| Anwendung: | Analytical reference standard, anorectic, appetite suppressant, serotonin 5-HT2c receptor agonist |
| CAS | 846589-98-8 |
| MW: | 232.2 D |
ab 259,00 €
Eplivanserin Mixture
Artikelnummer: Cay43749-10
A mixture of SR 46349 and SR 46615
| Schlagworte: | SR 46349 and SR 46615 Mixture, SR 46349/SR 46615, SR 46349B and SR 46615 Mixture, SR 46349B/SR 46615,... |
| Anwendung: | SR 46349 / SR 46615 mixture |
| CAS | 130581-13-4 |
| MW: | 328.39 D |
ab 68,00 €
Serotonin (hydrochloride)
Artikelnummer: Cay14332-100
Serotonin is a monoamine neurotransmitter that is biochemically derived from tryptophan and produced in serotonergic neurons in the central nervous system and in enterochromaffin cells in the gastrointestinal tract. Serotonin is important in the regulation of mood, sleep, vomiting, sexuality, and appetite. Low...
| Schlagworte: | 5-HT, 5-Hydroxytryptamine, 3-(2-aminoethyl)-1H-indol-5-ol, monohydrochloride |
| Anwendung: | Monoamine neurotransmitter |
| CAS | 153-98-0 |
| MW: | 212.7 D |
ab 75,00 €
Fananserin
Artikelnummer: Cay33216-10
A 5-HT2 antagonist (IC50 = 0.12 nM for the rat receptor), selective for 5-HT2 over 5-HT1A, 5-HT3, alpha1-AR, dopamine D2 (IC50s = 75, 6,600, 4.3, and 390 nM for the rat receptors), and histamine H1 receptors (IC50 = 50 nM for the guinea pig receptor), an antagonist of the dopamine D4 receptor (Ki = 2.93 nM for the...
| Schlagworte: | RP-62203, 2-[3-[4-(4-fluorophenyl)-1-piperazinyl]propyl]-2H-naphth[1,8-cd]isothiazole, 1,1-dioxide |
| Anwendung: | 5-HT2 antagonist |
| CAS | 127625-29-0 |
| MW: | 425.52 D |
ab 72,00 €
Quipazine (maleate)
Artikelnummer: Cay42262-1
A 5-HT2A, 5-HT2B, and 5-HT2C receptor agonist, induces calcium accumulation in CHO-K1 cells expressing 5-HT2A, 5-HT2B, or 5-HT2C receptors (EC50s = 309.03, 177.83, and 338.84 nM, respectively, for the human receptors), binds to the 5-HT3 receptor (Ki = 2.1 nM), decreases food intake in rats at 2.5, 5, or 10 mg/kg,...
| Schlagworte: | 2-(1-piperazinyl)-quinoline, (2Z)-2-butenedioate (1:2) |
| Anwendung: | 5-HT2A/5-HT2B/5-HT2C receptor agonist |
| CAS | 150323-78-7 |
| MW: | 445.4 D |
ab 97,00 €