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Zu "K04153" wurden 149 Artikel gefunden!
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NEU
Artikelnummer: Cay40435-1
Buspirone-d8 is intended for use as an internal standard for the quantification of buspirone by GC- or LC-MS. Buspirone is a partial agonist of the serotonin (5-HT) receptor subtype 5-HT1A. It binds to the 5-HT1A receptor (IC50 = 5.6 nM) and inhibits forskolin-induced adenylate cyclase activity in primary CA1...
Schlagworte: | MJ9022-1-d8, 8-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl-1,1,2,2,3,3,4,4-d8]-8-azaspiro[4.5]decane-7,9-dione,... |
Anwendung: | GC-MS, LC-MS internal standard, quantification, serotonin 5-HT1A receptor partial agonist |
CAS | 1216761-39-5 |
MW: | 430 D |
ab 80,00 €
Artikelnummer: Cay39191-1
NAS-181 is an antagonist of the serotonin (5-HT) receptor subtype 5-HT1B (Ki = 47 nM for the rat receptor). It is selective for 5-HT1B over 5-HT1A, 5-HT2A, 5-HT2C, 5-HT6, and 5-HT7 (Kis = >3,000 nM for all for the rat receptors). NAS-181 (100 or 1,000 nM) potentiates potassium-stimulated 5-HT release in isolated and...
Schlagworte: | (2R)-2-[[[3-(4-morpholinylmethyl)-2H-1-benzopyran-8-yl]oxy]methyl]-morpholine, bimethanesulfonate |
Anwendung: | 5-HT1B receptor antagonist |
CAS | 1217474-40-2 |
MW: | 538.6 D |
ab 74,00 €
Artikelnummer: Cay39918-10
Ipsapirone is a partial agonist of the serotonin (5-HT) receptor subtype 5-HT1A (Ki = 10 nM in hippocampal membranes). It reduces 5-HT release in the rat ventral hippocampus in vivo. Low doses of ipsapirone decrease, while high doses increase, extracellular dopamine release in the murine nucleus accumbens....
Schlagworte: | 2-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-1,2-benzisothiazol-3(2H)-one, 1,1-dioxide |
Anwendung: | 5-HT1A receptor partial agonist |
CAS | 95847-70-4 |
MW: | 401.5 D |
ab 106,00 €
Artikelnummer: ELK-ELK4282.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human 5HTR1A. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human 5HTR1A....
Schlagworte: | G-21, HTR1A, 5-HT1A, 5-HT-1A, ADRB2RL1, Serotonin receptor 1A, 5-hydroxytryptamine receptor 1A |
Anwendung: | ELISA |
Spezies-Reaktivität: | human |
ab 365,00 €
Artikelnummer: ELK-ELK8645.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse 5HTR1A. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse 5HTR1A....
Schlagworte: | Htr1a, 5-HT1A, Gpcr18, 5-HT-1A, Serotonin receptor 1A, 5-hydroxytryptamine receptor 1A |
Anwendung: | ELISA |
Spezies-Reaktivität: | mouse |
ab 365,00 €
Artikelnummer: Cay14332-50
Serotonin is a monoamine neurotransmitter that is biochemically derived from tryptophan and produced in serotonergic neurons in the central nervous system and in enterochromaffin cells in the gastrointestinal tract. Serotonin is important in the regulation of mood, sleep, vomiting, sexuality, and appetite. Low...
Schlagworte: | 5-HT, 5-Hydroxytryptamine, 3-(2-aminoethyl)-1H-indol-5-ol, monohydrochloride |
Anwendung: | Monoamine neurotransmitter |
CAS | 153-98-0 |
MW: | 212.7 D |
ab 50,00 €
Artikelnummer: Cay36791-100
2-bromo LSD (solution) (Cay-36791) is an analytical reference material categorized as a lysergamide. Unlike LSD (Cay-28289), 2-bromo LSD does not induce myoclonic jumping activity in guinea pigs, indicating a lack of hallucinogenic potential. This product is intended for research and forensic applications.Formal...
Schlagworte: | BOL-148, Bromolysergic Acid diethylamide, Bromolysergide,... |
Anwendung: | Analytical reference material, Lysergamide, Neutral antagonist |
CAS | 478-84-2 |
MW: | 402.3 D |
158,00 €
Artikelnummer: Cay22906-10
Brexpiprazole is a serotonin (5-HT) and dopamine receptor modulator that has high affinity (Ki = 1A and 5-HT2A serotonin, dopamine D2L, and alpha1B-, and alpha2C-adrenergic receptors in CHO cell membranes expressing the human receptors. It acts as a partial agonist of 5-HT1A, D2L, and D3 receptors (EC50s = 0.49,...
Schlagworte: | OPC 34712, 7-[4-(4-benzo[b]thien-4-yl-1-piperazinyl)butoxy]-2(1H)-quinolinone |
Anwendung: | 5-HT1A-receptor agonist |
CAS | 913611-97-9 |
MW: | 433.6 D |
ab 60,00 €
Artikelnummer: Cay22028-1
Buspirone (hydrochloride) (Cay-22028) is an analytical reference standard that is categorized as an anxiolytic. It modulates serotonin and dopamine receptors, undergoes rapid first-pass metabolism, and is metabolized to phenylpiperazine (Cay-11203), which has high affinity for alpha-adrenergic receptors. This...
Schlagworte: | MJ9022-1, 8-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-8-azaspiro[4.5]decane-7,9-dione, monohydrochloride |
Anwendung: | Analytical reference standard, Anxiolytic, Serotonin 5-HT1A receptor agonist |
CAS | 33386-08-2 |
MW: | 422 D |
ab 77,00 €
Artikelnummer: Cay23847-25
Dihydroergotamine is a derivative of ergotamine and an agonist of the serotonin (5-HT) receptor subtypes 5-HT1B and 5-HT1D (Kis = 0.3 and 2.5 nM, respectively, for human receptors). It binds to dopamine D2 and D3 as well as 5-HT2A receptors (K0.5s = 5, 16, and 38 nM, respectively) but has lower affinity for D1,...
Schlagworte: | (+)-Dihydroergotamine, (5'alpha,10alpha)-9,10-dihydro-12'-hydroxy-2'-methyl-5'-(phenylmethyl)-ergotaman-3',6',18-trione,... |
Anwendung: | alpha1-Adrenergic receptor & serotonin receptor agonist/antagonist, dopamine D2 receptor agonist |
CAS | 6190-39-2 |
MW: | 679.8 D |
ab 50,00 €
Artikelnummer: LKT-F4532.100
Flibanserin is an agonist at 5-HT1A receptors and an antagonist at 5-HT2A receptors. Flibanserin is clinically used to treat hypoactive sexual disorder in females. Flibanserin also decreases dystonia induced by L-DOPA and quinelorane in animal models of Parkinson's disease.
Anwendung: | 5-HT1A-receptor agonist, 5-HT2-receptor antagonist |
CAS | 167933-07-5 |
MW: | 390.4 D |
ab 104,00 €
Artikelnummer: Cay14599-5
WAY-100635 is a potent, silent antagonist of serotonin 5-HT1A receptors with an IC50 value of 2.2 nM (Ki = 0.8 nM) for inhibiting 5-HT1A receptors in rat hippocampal membranes. Because it displays 100-fold selectivity for 5-HT1A over other 5-HT subtypes, WAY-100635 is classically used to examine the distribution and...
Schlagworte: | N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-N-2-pyridinyl-cyclohexanecarboxamide, 2Z-butenedioate |
Anwendung: | 5-HT1A receptor antagonist |
CAS | 1092679-51-0 |
MW: | 538.6 D |
ab 109,00 €