Zu "K04145" wurden 275 Artikel gefunden!
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Cariprazine N-oxide
Artikelnummer: Cay44583-10
Cariprazine N-oxide is a degradation product of the atypical antipsychotic cariprazine (Cay-31446, Cay-24025). It is formed via oxidative degradation induced by hydrogen peroxide or 3-chloroperoxybenzoic acid (MCPBA). Formal Name:...
| Schlagworte: | N'-[trans-4-[2-[4-(2,3-dichlorophenyl)-1-oxido-1-piperazinyl]ethyl]cyclohexyl]-N,N-dimethyl-urea |
| Anwendung: | Cariprazine degradation product |
| CAS | 1084891-96-2 |
| MW: | 443.41 D |
ab 64,00 €
(±)-Sulpiride (CRM)
Artikelnummer: Cay44579-1
(±)-Sulpiride (CRM) (Cay-44579) is a certified reference material categorized as an atypical antipsychotic. Formulations containing (±)-sulpiride have been used in the treatment of schizophrenia, depression, and anxiety. This product is intended for analytical forensic applications. This product is also available as...
| Schlagworte: | (R,S)-(±)-Sulpiride, rac-Sulpiride, RD 1403, 5-(aminosulfonyl)-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxy,benzamide |
| Anwendung: | Certified reference material, atypical antipsychotic, Dopamine D2-receptor antagonist |
| CAS | 15676-16-1 |
| MW: | 341.43 D |
180,00 €
Melperone (hydrochloride) (CRM)
Artikelnummer: Cay44822-1
Melperone (hydrochloride) (CRM) (Cay-44822) is a certified reference material categorized as an atypical antipsychotic. This product is intended for analytical forensic applications. This product is also available as a general research tool (Cay-19770).
| Schlagworte: | FG 5111, Methylperone, 1-(4-fluorophenyl)-4-(4-methyl-1-piperidinyl)-1-butanone, monohydrochloride |
| Anwendung: | Certified reference material, atypical antipsychotic |
| CAS | 1622-79-3 |
| MW: | 299.81 D |
160,00 €
Anti-DRD2 / Dopamine D2 Receptor
Artikelnummer: NSJ-F54240-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. This gene encodes the D2 subtype of the dopamine receptor. This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia, other mutations have been associated with schizophrenia. Alternative splicing of this...
| Schlagworte: | Anti-DRD2, Anti-Dopamine D2 receptor, Anti-D(2) dopamine receptor, DRD2 Antibody / Dopamine D2 Receptor |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 361,00 €
Cabergoline
Artikelnummer: TGM-T14853-1mg
Description: Cabergoline (FCE-21336) is an ergot derived-dopamine D2-like receptor agonist. It has high affinity for D2, D3, and 5-HT2B receptors (Ki=0.7, 1.5, and 1.2, respectively).Cabergoline permits rapid and effective hormonal and tumor control by normalizing prolactin-producing pituitary adenomas levels....
| Schlagworte: | FCE-21336 |
| Anwendung: | Targets dopamine receptor D2 (DRD2) |
| CAS | 81409-90-7 |
| MW: | 451.6 D |
ab 33,00 €
Pergolide (mesylate)
Artikelnummer: Cay26085-25
Pergolide is a potent dopamine D1 and D2 receptor agonist (Kis = 111 and 0.495 nM, respectively, for rat striatal receptors). It depresses dopaminergic firing in paralyzed rats (ED50 = 2-selective antagonist spiperone or the dopamine D1-selective antagonist SCH 23390 (Cay-15631). Pergolide (0.025 and 0.05 mg/kg)...
| Schlagworte: | LY127809, NSC 319773, 8beta-[(methylthio)methyl]-6-propyl-ergoline, monomethanesulfonate |
| Anwendung: | Dopamine D1-receptor agonist, dopamine D2-receptor agonist |
| CAS | 66104-23-2 |
| MW: | 410.6 D |
ab 76,00 €
COVID-19 Forschung
Haloperidol
Artikelnummer: Cay12014-100
Haloperidol is a typical antipsychotic and dopamine D2-like receptor antagonist (Kis = 0.6, 0.2, and 22 nM, for D2, D3, and D4 receptors, respectively). It also acts as an inverse agonist at dopamine D2 and D3 receptors (IC50s = 0.8 and 0.6 nM, respectively). Haloperidol also binds to alpha1- and alpha2- adrenergic...
| Schlagworte: | McN-JR 1625, NSC 170973, NSC 615296, R 1625, 4-[4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl]-1-(4-fluorophenyl)-1-butanone |
| Anwendung: | Dopamine D2 receptor antagonist |
| CAS | 52-86-8 |
| MW: | 375.9 D |
ab 55,00 €
Risperidone
Artikelnummer: Cay13629-10
Risperidone is an atypical antipsychotic that binds to dopamine D2 receptors (Ki = 3 nM) and the serotonin (5-HT) receptor subtype 5-HT2A (Ki = 0.12 nM). It also binds to dopamine D4, alpha1- and alpha2-adrenergic, 5-HT1C, 5-HT1D, and histamine H1 receptors (Kis = 7, 0.81, 7.3, 47, 52, and 2.1 nM, respectively)....
| Schlagworte: | Apexidone, Psychodal, R 64766,... |
| Anwendung: | Receptor antagonist |
| CAS | 106266-06-2 |
| MW: | 410.5 D |
ab 105,00 €
AMI-193
Artikelnummer: Cay43100-10
A 5-HT2A and dopamine D2 receptor antagonist, selective for the 5-HT2A receptor over 5-HT2B and 5-HT1C receptors (Kis = 22.39, 977.24, and 1,548.82 nM, respectively) but does bind to the 5-HT1A receptor (Ki = 50 nM), selectively binds to the dopamine D2 receptor over the dopamine D1 receptor (Kis = 3 and 2,530 nM,...
| Schlagworte: | Spiramide, 8-[3-(4-fluorophenoxy)propyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one |
| Anwendung: | 5-HT2A / dopamine D2 receptor antagonist |
| CAS | 510-74-7 |
| MW: | 383.47 D |
ab 112,00 €
Thioridazine (hydrochloride)
Artikelnummer: Cay14400-1
Thioridazine is a typical antipsychotic. It binds to dopamine D2, histamine H1, M3 muscarinic, and alpha1- and alpha2-adrenergic receptors (Kis = 5-341.3 nM), as well as the serotonin (5-HT) receptor subtypes 5-HT1A, 5-HT2A, 5-HT2C, 5-HT6, and 5-HT7 (Kis = 10-180.7 nM). Thioridazine (5 mg/kg) reduces...
| Schlagworte: | Aldazine, NSC 186060, 10-[2-(1-methyl-2-piperidinyl)ethyl]-2-(methylthio)-10H-phenothiazine, monohydrochloride |
| Anwendung: | Dopamine D2-receptor antagonist |
| CAS | 130-61-0 |
| MW: | 407 D |
ab 51,00 €
Trifluoperazine (hydrochloride)
Artikelnummer: Cay15068-1
Trifluoperazine (TFP) is a phenothiazine compound with anti-adrenergic and anti-dopaminergic actions typical of antipsychotic agents. It antagonizes adrenergic receptors, with selectivity for alpha1 over the alpha2 subtypes (Kis = 24, 653, 163, and 391 nM for alpha1A, alpha2A, alpha2B, and alpha2C, respectively)....
| Schlagworte: | SKF 5019, TFP, 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-10H-phenothiazine, dihydrochloride |
| Anwendung: | Dopamine receptor D2 antagonist |
| CAS | 440-17-5 |
| MW: | 480.4 D |
ab 51,00 €
Corypalmine
Artikelnummer: Cay42467-1
Corypalmine is an isoquinoline alkaloid that has been found in F. recisa and has receptor antagonist and antifungal activities. It is an antagonist of dopamine D1, D2, D3, and D5 receptors (Kis = 199, 42. 262, and 313 nM, respectively). Corypalmine is active against C. albicans, C. glabratas, C. krusei, C....
| Schlagworte: | Tetrahydrojatrorrhizine, 5,8,13,13a-tetrahydro-2,9,10-trimethoxy-6H-dibenzo[a,g]quinolizin-3-ol |
| Anwendung: | Isoquinoline alkaloid, dopamine receptor antagonist, antifungal agent |
| CAS | 27313-86-6 |
| MW: | 341.4 D |
ab 107,00 €