Zu "K04141" wurden 155 Artikel gefunden!
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CHO-K1/ADRB1/Galpha15 Stable Cell Line
Artikelnummer: GSC-M00269
Recombinant CHO-K1 cells stably overexpress human adrenoceptor beta 1 (ADRB1) on the surface and contain high levels of G protein Galphas to couple with the receptor in downstream signaling pathways.
| Schlagworte: | ADRB1, Beta-1 adrenoreceptor, Beta-1 adrenergic receptor |
11.424,00 €
DL 071-IT
Artikelnummer: Cay33364-1
DL 071-IT is an antagonist of beta-adrenergic receptors (beta-ARs). InChI: InChI=1S/C15H21NO4.ClH/c1-15(2,3)16-7-11(17)9-19-12-6-4-5-10-8-20-14(18)13(10)12,/h4-6,11,16-17H,7-9H2,1-3H3,1H InChIKey: KTIQCDLYPPAYBF-UHFFFAOYSA-N SMILES: O=C1OCC2=C1C(OCC(CNC(C)(C)C)O)=CC=C2.Cl
| Schlagworte: | Afurolol, 7-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]-1(3H)-isobenzofuranone, monohydrochloride |
| Anwendung: | beta-Adrenergic receptor antagonist |
| CAS | 55104-39-7 |
| MW: | 315,79 D |
ab 134,00 €
Landiolol (hydrochloride)
Artikelnummer: Cay44229-10
Landiolol is an antagonist of the beta1-adrenergic receptor (beta1-AR). It selectively induces relaxation of isolated and perfused guinea pig atrial strips that endogenously express beta1-ARs over isolated and perfused guinea pig tracheal strips that endogenously express beta2-ARs (pA2s = 6. and 4. respectively)....
| Schlagworte: | ONO-1101 |
| Anwendung: | beta1-adrenergic receptor (beta1-AR) antagonis |
| CAS | 144481-98-1 |
| MW: | 546.06 D |
ab 72,00 €
ICI 89406
Artikelnummer: Cay42370-10
A ß1-adrenergic receptor antagonist (IC50 = 4.2 nM), selective for ß1-adrenergic receptors over ß2-adrenergic receptors (IC50 = 678 nM), acts as a partial agonist at ß1- and ß2-adrenergic receptors, inducing cAMP accumulation in CHO-K1 cells expressing the human receptors (EC50s = 0.81 and 60.26 nM, respectively)....
| Schlagworte: | N-[2-[[3-(2-cyanophenoxy)-2-hydroxypropyl]amino]ethyl]-N'-phenyl-urea |
| Anwendung: | SS1-adrenergic receptor antagonist |
| CAS | 53671-71-9 |
| MW: | 354.4 D |
ab 73,00 €
Isoproterenol (hydrochloride)
Artikelnummer: Cay15592-100
Isoproterenol is an agonist of beta1- and beta2-adrenergic receptors (beta1- and beta2-ARs, Kis = 224 and 458 nM, respectively. It is selective for beta1- and beta2-ARs over beta3-ARs (Ki = 1,570 nM). Isoproterenol inhibits contractions in isolated field-stimulated rat vas deferens (EC50 = 45.6 nM). In vivo,...
| Schlagworte: | Isoprenaline, NSC 37745, NSC 89747, 4-[1-hydroxy-2-[(1-methylethyl)amino]ethyl], monohydrochloride |
| Anwendung: | beta1/2/3-adrenergic receptor agonist |
| CAS | 51-30-9 |
| MW: | 247.7 D |
ab 53,00 €
Timolol Maleate
Artikelnummer: LKT-T3350.1
A b-Adrenergic receptor selective antagonist used as a antiglaucoma agent.
| Anwendung: | beta-adrenergic receptor antagonist |
| CAS | 26921-17-5 |
| MW: | 432,5 D |
ab 144,00 €
(±)-Talinolol
Artikelnummer: Cay16116-5
(±)-Talinolol is a beta1-selective adrenoceptor antagonist well known for its cardioprotective and antihypertensive activity. By blocking beta1-adrenergic receptors, talinolol delays the conduction of stimuli in the AV node, reduces the sino-atrial conduction time, and impedes the sinus node automaticity. Because...
| Schlagworte: | N-cyclohexyl-N'-[4-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]phenyl]-urea |
| Anwendung: | beta1-adrenergic receptor antagonist |
| CAS | 57460-41-0 |
| MW: | 363.5 D |
ab 67,00 €
Metoprolol Tartrate
Artikelnummer: LKT-M1879.5
Metoprolol tartrate is a beta1-adrenergic blocker.
| Anwendung: | beta1-adrenergic blocker |
| CAS | 56392-17-7 |
| MW: | 684,82 D |
ab 100,00 €
Propranolol Hydrochloride
Artikelnummer: LKT-P6865.1
Propranolol HCl is a sympatholytic non-selective beta blocker. Sympatholytics are used to treat hypertension, anxiety and panic.
| CAS | 318-98-9 |
| MW: | 295.8 D |
ab 68,00 €
Esmolol (hydrochloride)
Artikelnummer: Cay22581-10
Esmolol is a beta1-adrenergic receptor (beta1-AR) antagonist. It binds to beta1-ARs (Kd = 100 nM in isolated cardiac myocytes) and is 34-fold selective for beta1- over beta2-ARs. Esmolol also inhibits L-type Ca2+ currents (ICa.L) and the fast Na+ current (INa) in rat cardiac myocytes (IC50s = 50 and 169 µM,...
| Schlagworte: | ASL 8052, 4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]-benzenepropanoic acid, methyl ester, monohydrochloride |
| Anwendung: | beta1-Adrenergic receptor antagonist |
| CAS | 81161-17-3 |
| MW: | 331.8 D |
ab 49,00 €
Bufuralol (hydrochloride)
Artikelnummer: Cay17794-1
Bufuralol is a non-selective antagonist of beta-adrenergic receptors (beta-ARs) that also has partial agonist activity. It decreases mean arterial blood pressure and increases abdominal aortic blood flow in anesthetized cats when administered intravenously at doses of 0.3 and 1 mg/kg. Bufuralol is hydroxylated at...
| Schlagworte: | (±)-Bufuralol, DL-Bufuralol, Ro 3-4787, alpha-[[(1,1-dimethylethyl)amino]methyl]-7-ethyl-2-benzofuranmethanol,... |
| Anwendung: | beta-adrenoceptor antagonist |
| CAS | 60398-91-6 |
| MW: | 297.8 D |
ab 122,00 €
Sotalol (hydrochloride)
Artikelnummer: Cay16136-10
Sotalol is a non-selective antagonist of beta-adrenergic receptors (beta-ARs, IC50s = 8.9 and 5.2 µM for beta1- and beta2-ARs, respectively) and a class III antiarrhythmic agent. It decreases delayed outward potassium currents (IK) in guinea pig ventricular cells and prolongs action potential duration in...
| Schlagworte: | (±)-Sotalol, DL-Sotalol, MJ1999, N-[4-[1-hydroxy-2-[(1-methylethyl)amino]ethyl]phenyl]-methanesulfonamide, monohydrochloride |
| Anwendung: | beta1/2-adrenergic receptor antagonist |
| CAS | 959-24-0 |
| MW: | 308.8 D |
ab 49,00 €