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Dexmedetomidine
Dexmedetomidine

Artikelnummer: Cay39544-10

Dexmedetomidine is an agonist of alpha2-adrenergic receptors (alpha2-ARs). It selectively binds to alpha2-ARs over alpha1-ARs (Kis = 0.015 and 5 nM, respectively). In vivo, dexmedetomidine (50 µg/kg) prevents increases in cardiac troponin I (CTnI), a marker of myocardial injury, as well as reduces myocardial...
Schlagworte: MPV 1440, 5-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole
Anwendung: Alpha2-AR agonist, sedative-hypnotic
CAS 113775-47-6
MW: 200.3 D
ab 53,00 €
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Anti-ADRA2B / Alpha-2B Adrenergic Receptor
Anti-ADRA2B / Alpha-2B Adrenergic Receptor

Artikelnummer: NSJ-F54979-0.08ML

In 1X PBS, pH 7.4, with 0.09% sodium azide. Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from...
Schlagworte: Anti-ADRA2B, Anti-ADRA2L1, Anti-Alpha-2BAR, Anti-Alpha-2B adrenoceptor, Anti-Alpha-2B adrenoreceptor, Anti-Alpha-2B...
Anwendung: WB, IF, FC, IHC (paraffin)
Wirt: Rabbit
Spezies-Reaktivität: human
ab 326,00 €
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Xylazine
Xylazine

Artikelnummer: Cay14113-10

Xylazine is an agonist of alpha2-adrenergic receptors (Ki = 194 nM). It is an analog of clonidine, an alpha2-adrenergic receptor agonist used to reduce blood pressure. Xylazine is used for sedation, anesthesia, and analgesia in non-human mammals. This product is also available as an analytical reference standard...
Schlagworte: N-(2,6-dimethylphenyl)-5,6-dihydro-4H-1,3-thiazin-2-amine
Anwendung: alpha2 adrenergic receptor agonist
CAS 7361-61-7
MW: 220.3 D
ab 48,00 €
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Xylazine (hydrochloride)
Xylazine (hydrochloride)

Artikelnummer: Cay36692-500

Xylazine is an agonist of alpha2-adrenergic receptors (Ki = 194 nM). It is an analog of clonidine, an alpha2-adrenergic receptor agonist used to reduce blood pressure. Xylazine is used for sedation, anesthesia, and analgesia in non-human mammals. This product is also available as an analytical reference standard...
Schlagworte: BAY-Va 1470, N-(2,6-dimethylphenyl)-5,6-dihydro-4H-1,3-thiazin-2-amine, monohydrochloride
Anwendung: Alpha2-adrenergic receptors agonist
CAS 23076-35-9
MW: 256.8 D
ab 35,00 €
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Centhaquin
Centhaquin

Artikelnummer: Cay36929-1

Centhaquin is a resuscitative agent. It binds to serotonin (5-HT) receptors in isolated rat cerebral cortex and brainstem membranes (Kis = 178.9 and 103.7 nM, respectively). Centhaquin (0.05-0.45 mg/kg) increases the latency to tail-flick in mice, an effect that can be reversed by the alpha2A-adenergic receptor...
Schlagworte: Centhaquine, PMZ-2010, 2-[2-[4-(3-methylphenyl)-1-piperazinyl]ethyl]-quinoline
Anwendung: Resuscitative agent, alpha-2B adrenergic receptor agonist
CAS 57961-90-7
MW: 331.5 D
ab 58,00 €
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Detomidine (hydrochloride)
Detomidine (hydrochloride)

Artikelnummer: Cay38583-5

Detomidine (hydrochloride) (Cay-38583) is an analytical reference standard categorized as a sedative. Detomidine has sedative activity in horses. Formulations containing detomidine have been used as veterinary sedatives. This product is intended for analytical forensic applications. This product is also available as...
Schlagworte: MPV 253AII, 5-[(2,3-dimethylphenyl)methyl]-1H-imidazole, monohydrochloride
Anwendung: Analytical reference standard, sedative, alpha2-Adrenergic receptor agonist
CAS 90038-01-0
MW: 222.7 D
ab 98,00 €
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Medetomidine (hydrochloride) (CRM)
Medetomidine (hydrochloride) (CRM)

Artikelnummer: Cay38807-1

Medetomidine (hydrochloride) (CRM) (Cay-38807) is a certified reference material categorized as a sedative. Medetomidine induces sedation in dogs. It has analgesic activity alone, and an additive analgesic effect in combination with fentanyl (Cay-ISO60197, Cay-14719, Cay-23580) or morphine (Cay-ISO60147, Cay-15464),...
Schlagworte: MPV 785, 5-[1-(2,3-dimethylphenyl)ethyl]-1H-imidazole, monohydrochloride
Anwendung: Certified reference material, sedative, alpha2-adrenergic receptor agonist
CAS 86347-15-1
MW: 236.7 D
164,00 €
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Tizanidine (hydrochloride)
Tizanidine (hydrochloride)

Artikelnummer: Cay38559-5

Tizanidine (hydrochloride) (Cay-38559) is an analytical reference standard categorized as a muscle relaxant. Tizanidine inhibits alpha- and gamma-rigidity in rats, reflex muscle tone in rabbits, and the linguomandibular reflex in cats. It has been associated with fatal overdoses. Formulations containing tizanidine...
Schlagworte: DS 103-282, 5-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-2,1,3-benzothiadiazol-4-amine, monohydrochloride
Anwendung: Analytical reference standard, muscle relaxant, alpha2-Adrenergic receptor agonist
CAS 64461-82-1
MW: 290.2 D
ab 98,00 €
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Romifidine (hydrochloride)
Romifidine (hydrochloride)

Artikelnummer: Cay38581-5

Romifidine (hydrochloride) (Cay-38581) is an analytical reference standard categorized as a sedative and analgesic. Romifidine has antinociceptive and sedative activities in donkeys. Formulations containing romifidine have been used as veterinary sedatives. This product is intended for research and forensic...
Schlagworte: N-(2-bromo-6-fluorophenyl)-4,5-dihydro-1H-imidazol-2-amine, monohydrochloride
Anwendung: Analytical reference standard, sedative, analgesic, alpha2-Adrenergic receptor agonist
CAS 65896-14-2
MW: 294.6 D
ab 98,00 €
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TDIQ (hydrochloride)
TDIQ (hydrochloride)

Artikelnummer: Cay16083-5

TDIQ (hydrochloride) is an analytical reference standard that is classified as a phenylalkylamine. It is related in structure to amphetamines but does not appear to affect locomotor activity. TDIQ is a partial agonist of alpha2A-, alpha2B-, and alpha2C-adrenergic receptors (Kis = 75, 95, and 65 nM, respectively) but...
Schlagworte: 6,7-Methylenedioxy-1,2,3,4-tetrahydroisoquinoline, MDTHIQ, 5,6,7,8-tetrahydro-1,3-dioxolo[4,5-g]isoquinoline,...
Anwendung: Analytical reference standard, Phenylalkylamine, Adrenergic receptor alpha2A/B/C partial agonist
CAS 15052-05-8
MW: 213.7 D
ab 98,00 €
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Xylazine
Xylazine

Artikelnummer: Cay22641-50

Xylazine (Cay-22641) is an analytical reference standard categorized as an anesthetic. It has been used as an adulterant in drugs of abuse and misused, leading to non-fatal and fatal intoxications. This product is intended for use in analytical forensic applications. This product is also available as a general...
Schlagworte: N-(2,6-dimethylphenyl)-5,6-dihydro-4H-1,3-thiazin-2-amine
Anwendung: Analytical reference standard, anesthetic, alpha2-adrenergic receptor agonist
CAS 7361-61-7
MW: 220.3 D
ab 84,00 €
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Levonordefrin
Levonordefrin

Artikelnummer: Cay23993-10

Levonordefrin is the (-)-enantiomer of nordefrin, a synthetic derivative of norepinephrine (Cay-16673), that acts as a vasoconstrictor. Levonordefrin (1-5 µg/kg) rapidly increases blood pressure and heart rate in anesthetized dogs and has a more potent effect on blood pressure than the dextronordefrin enantiomer. It...
Schlagworte: (-)-3,4-dihydroxy Norephedrine, (-)-alpha-methyl Noradrenaline, Corbadrine,...
Anwendung: Vasoconstrictor, alpha2-Adrenergic receptor agonist
CAS 829-74-3
MW: 183.2 D
ab 84,00 €
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