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Zu "K04136" wurden 60 Artikel gefunden!
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Artikelnummer: IB-IB31101
This is an all-inclusive cell-based luciferase reporter assay kit targeting the the Human Adrenoreceptor Alpha 1B (ADRA1B). INDIGO's ADRA1A reporter assay utilizes proprietary mammalian cells that have been engineered to provide constitutive expression of the ADRA1B. In addition to ADRA1B Reporter Cells, this kit...
Schlagworte: | ADRA1B, Alpha-1B adrenoceptor, Alpha-1B adrenoreceptor, Alpha-1B adrenergic receptor |
Anwendung: | Functional activity screening |
Spezies-Reaktivität: | human |
1.448,00 €
Artikelnummer: IB-IB31102
This is an all-inclusive cell-based luciferase reporter assay kit targeting the the Human Adrenoreceptor Alpha 1B (ADRA1B). INDIGO's ADRA1A reporter assay utilizes proprietary mammalian cells that have been engineered to provide constitutive expression of the ADRA1B. In addition to ADRA1B Reporter Cells, this kit...
Schlagworte: | ADRA1B, Alpha-1B adrenoceptor, Alpha-1B adrenoreceptor, Alpha-1B adrenergic receptor |
Anwendung: | Functional activity screening |
Spezies-Reaktivität: | human |
3.803,00 €
Artikelnummer: Cay33546-1
Midodrine-d6 is intended for use as an internal standard for the quantification of midodrine (Cay-17349) by GC- or LC-MS. Midodrine is a prodrug form of the alpha1-adrenergic receptor (alpha1-AR) agonist desglymidodrine. It is converted to desglymidodrine by enzymatic hydrolysis. Midodrine (5 mg/kg) increases mean...
Schlagworte: | 2-amino-N-[2-[2,5-di(methoxy-d3)phenyl]-2-hydroxyethyl]-acetamide, monohydrochloride |
Anwendung: | GC-MS, LC-MS internal standard, quantification, alpha1-adrenergic receptor agonist |
CAS | 1188265-43-1 |
MW: | 296.8 D |
ab 135,00 €
Artikelnummer: Cay21927-5
Octodrine (hydrochloride) (Cay-21927) is an analytical reference standard categorized as a stimulant. This product is intended for research and forensic applications.Formal Name: 6-methyl-2-heptanamine, monohydrochloride. CAS Number: 5984-59-8. Molecular Formula: C8H19N . HCl. Formula Weight: 165.7. Purity: >95%....
Schlagworte: | 1,5-dimethyl Hexylamine, 2-Amino-6-methylheptane, NSC 27116, 6-methyl-2-heptanamine, monohydrochloride |
Anwendung: | Analytical reference standard, Stimulant, Adrenergic receptor agonist |
CAS | 5984-59-8 |
MW: | 165.7 D |
ab 60,00 €
Artikelnummer: Cay16673-100
(-)-Norepinephrine is the endogenous isomer of (±)-norepinephrine (Cay-35580) that acts as a neurotransmitter and hormone and is biosynthesized from dopamine by dopamine beta-hydroxylase. It is an agonist of adrenergic receptors (Ki values are 330, 56, and 740 nM for alpha1, alpha2, and beta1 adrenoceptors,...
Schlagworte: | Arterenol, Levarterenol, L-Noradrenaline, NE, 4-[(1R)-2-amino-1-hydroxyethyl]-1,2-benzenediol... |
Anwendung: | Adrenergic receptor agonist, dopamine beta-hydroxylase metabolite |
CAS | 108341-18-0 |
MW: | 337.3 D |
ab 44,00 €
Artikelnummer: Cay29004-250
Urapidil is an antagonist of alpha1-adrenergic receptors (alpha1-ARs) and a partial agonist of the serotonin (5-HT) receptor subtype 5-HT1A. It selectively binds to alpha1- over alpha2-ARs (IC50s = 0.74 and 42 µM, respectively) and to 5-HT1A over 5-HT1B and 5-HT2 receptors (IC50s = 0.4, 20.4, and >10 µM,...
Schlagworte: | 6-[[3-[4-(2-methoxyphenyl)-1-piperazinyl]propyl]amino]-1,3-dimethyl-2,4(1H,3H)-pyrimidinedione monohydrochloride |
Anwendung: | alpha1-Adrenergic receptor antagonist |
CAS | 64887-14-5 |
MW: | 423.9 D |
ab 98,00 €
Artikelnummer: Cay18633-100
Doxazosin is a non-selective antagonist of alpha1-adrenergic receptors (alpha1-ARs, Kis = 3.16, 1, and 3.98 nM for alpha1A-, alpha1B-, and alpha1D-ARs, respectively). It inhibits norepinephrine-induced contractions in isolated rat aorta rings and human prostate strips with pA2 values of 8.8 and 8.2, respectively....
Schlagworte: | UK 33274-27, [4-(4-amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl](2,3-dihydro-1,4-benzodioxin-2-yl)-methanone,... |
Anwendung: | alpha1-adrenergic receptor antagonist |
CAS | 77883-43-3 |
MW: | 547.6 D |
ab 60,00 €
Artikelnummer: Cay27677-10
Rec 15/2615 is an antagonist of alpha1B-adrenergic receptors (alpha1B-ARs, Ki = 0.45 nM for the recombinant human receptor). It selectively inhibits alpha1B-ARs over alpha1A-, alpha1D-, and alpha1L-ARs (Kis = 7.59, 10.23, and 49 nM, respectively). Rec 15/2615 inhibits norepinephrine-induced contractions of isolated...
Schlagworte: | SB 216469, 1-[4-(4-amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-2-[2-methoxy-6-(1-methylethyl)phenoxy]-ethanone,... |
Anwendung: | alpha1B-adrenergic receptor antagonist |
CAS | 1782573-48-1 |
MW: | 568.5 D |
ab 60,00 €
Artikelnummer: ARG56233.100
Protein function: This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine (PE)-stimulated ERK signaling in...
Schlagworte: | Anti-ADRA1B, Anti-Alpha-1B adrenoceptor, Anti-Alpha-1B adrenoreceptor, Anti-Alpha-1B adrenergic receptor |
Anwendung: | WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse |
624,00 €
Artikelnummer: Cay17349-100
Midodrine is a prodrug form of the alpha1-adrenergic receptor (alpha1-AR) agonist desglymidodrine (Cay-35608). It is converted to desglymidodrine by enzymatic hydrolysis. Midodrine (5 mg/kg) increases mean arterial pressure (MAP) and decreases heart rate in normotensive rats. Formulations containing midodrine have...
Schlagworte: | 2-amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]-acetamide, monohydrochloride |
Anwendung: | alpha1-adrenergic receptor agonist prodrug |
CAS | 43218-56-0 |
MW: | 290.7 D |
ab 44,00 €
Artikelnummer: NSJ-R36077-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Alpha-1B adrenoceptor Protein function: This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system....
Schlagworte: | Anti-ADRA1B, Anti-Alpha-1B adrenoceptor, Anti-Alpha-1B adrenoreceptor, Anti-Alpha-1B adrenergic receptor, ADRA1B Antibody |
Anwendung: | WB, ELISA (peptide) |
Wirt: | Goat |
Spezies-Reaktivität: | human, mouse, rat, swine |
755,00 €
Artikelnummer: NSJ-R36216-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Alpha-1B-adrenergic receptor Protein function: This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger...
Schlagworte: | Anti-ADRA1B, Anti-Alpha-1B adrenoceptor, Anti-Alpha-1B adrenoreceptor, Anti-Alpha-1B adrenergic receptor, ADRA1B Antibody |
Anwendung: | WB, ELISA (peptide) |
Wirt: | Goat |
Spezies-Reaktivität: | human |
755,00 €