Zu "K04133" wurden 32 Artikel gefunden!

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Muscarinic Acetylcholine Receptor (mAChR) M5/NFAT Luciferase Reporter HEK293 Cell Line
Muscarinic Acetylcholine Receptor (mAChR) M5/NFAT...

Artikelnummer: BPS-82729

The Muscarinic Acetylcholine Receptor (mAChR) M5/NFAT Luciferase Reporter HEK293 Cell Line is a HEK293 cell line stably expressing the full-length human muscarinic acetylcholine receptor M5 (CHRM5/HM5/M5, accession number: AF498919) and a firefly luciferase reporter under the control of the NFAT (nuclear factor of...
Schlagworte: CHRM5, Muscarinic acetylcholine receptor M5,
Anwendung: Activator/inhibitor screening, drug discovery
Spezies-Reaktivität: human
9.897,00 €
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Muscarinic acetylcholine receptor M5 (CHRM5), recombinant human
Muscarinic acetylcholine receptor M5 (CHRM5), recombinant...

Artikelnummer: CSB-CF005385HU.100

Organism: Homo sapiens (Human). Source: in vitro E.coli expression system. Expression Region: 1-532aa. Protein Length: Full Length. Tag Info: N-terminal 10xHis-tagged. Target Protein Sequence: MEGDSYHNAT TVNGTPVNHQ PLERHRLWEV ITIAAVTAVV SLITIVGNVL VMISFKVNSQ LKTVNNYYLL SLACADLIIG IFSMNLYTTY ILMGRWALGS LACDLWLALD...
Schlagworte: CHRM5, Muscarinic acetylcholine receptor M5
Anwendung: Activity not tested
Exprimiert in: E.coli in vitro
Ursprungsart: human
MW: 66.1 kD
ab 1.458,00 €
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VU0365114
VU0365114

Artikelnummer: Cay33709-10

VU0365114 is a positive allosteric modulator of M5 muscarinic acetylcholine receptors (mAChRs). It increases ACh-induced calcium mobilization in CHO cells expressing human M5 mAChRs (EC50 = 2.7 µM) selectively over CHO cells expressing human M1-4 mAChRs (EC50s = >30 µM for all).Formal Name:...
Schlagworte: 1-([1,1'-biphenyl]-4-ylmethyl)-5-(trifluoromethoxy)-1H-indole-2,3-dione
Anwendung: Muscarinic M5 receptor positive allosteric modulator
CAS 1208222-39-2
MW: 397.4 D
ab 108,00 €
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VU 0238429
VU 0238429

Artikelnummer: TGM-T8007-100mg

Description: VU 0238429 (SCR-1481B1) is positive allosteric modulator of muscarinic acetylcholine receptor subtype 5 (mAChR5 or M5)( EC50 : 1.16 µM). Target: AChR. Smiles: COc1ccc(CN2C(=O)C(=O)c3cc(OC(F)(F)F)ccc23)cc1. References: Bridges TM, et al. Discovery of the first highly M5-preferring muscarinic...
Schlagworte: SCR-1481B1, VU0238429
Anwendung: Muscarinic M5 receptor positive allosteric modulator
CAS 1160247-92-6
MW: 351.28 D
ab 31,00 €
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CHRM5 Protein, Human, Recombinant (His)
CHRM5 Protein, Human, Recombinant (His)

Artikelnummer: TGM-TMPH-01717-100ug

Description: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover. CHRM5 Protein, Human, Recombinant (His)...
Schlagworte: Muscarinic acetylcholine receptor M5, CHRM5
MW: 31.5 kD
ab 281,00 €
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Muscarinic acetylcholine receptor M5 (CHRM5), partial, human, recombinant
Muscarinic acetylcholine receptor M5 (CHRM5), partial,...

Artikelnummer: CSB-EP005385HU1.1

Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 215-443aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: RIYRETEKRT KDLADLQGSD SVTKAEKRKP AHRALFRSCL RCPRPTLAQR ERNQASWSSS RRSTSTTGKP SQATGPSANW AKAEQLTTCS SYPSSEDEDK PATDPVLQVV YKSQGKESPG EEFSAEETEE TFVKAETEKS...
Schlagworte: CHRM5, Muscarinic acetylcholine receptor M5, Recombinant Human Muscarinic acetylcholine receptor M5 (CHRM5), partial
Anwendung: Activity not tested
Exprimiert in: E.coli
Ursprungsart: human
MW: 31.5 kD
ab 292,00 €
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Anti-CHRM5
Anti-CHRM5

Artikelnummer: CSB-PA006813.100

Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
Schlagworte: Anti-CHRM5, Anti-Muscarinic acetylcholine receptor M5, Acetylcholine receptor muscarinic 5 antibody, AChR antibody, AChR...
Anwendung: ELISA, WB, IF
Wirt: Rabbit
Spezies-Reaktivität: human
ab 126,00 €
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Anti-CHRM5
Anti-CHRM5

Artikelnummer: CSB-PA985994.100

Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: CHRM5. Antigen Species: Human
Schlagworte: Anti-CHRM5, Anti-Muscarinic acetylcholine receptor M5, Acetylcholine receptor muscarinic 5 antibody, AChR antibody, AChR...
Anwendung: ELISA, IHC
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
ab 167,00 €
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Anti-CHRM5
Anti-CHRM5

Artikelnummer: CSB-PA598098.100

Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: CHRM5. Antigen Species: Human
Schlagworte: Anti-CHRM5, Anti-Muscarinic acetylcholine receptor M5, Acetylcholine receptor muscarinic 5 antibody, AChR antibody, AChR...
Anwendung: ELISA, IHC
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
ab 167,00 €
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Scopolamine N-butylbromide
Scopolamine N-butylbromide

Artikelnummer: LKT-S1058.5

An antispasmodic agent.
Schlagworte: Butylscopolamine bromide
Anwendung: Muscarinic cholinergic receptor antagonist
CAS 149-64-4
MW: 440,38 D
ab 99,00 €
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Anti-M5 mAChR
Anti-M5 mAChR

Artikelnummer: ARG56244.100

Protein function: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover. [The UniProt Consortium]
Schlagworte: Anti-CHRM5, Anti-Muscarinic acetylcholine receptor M5
Anwendung: WB, ICC, IF
Wirt: Rabbit
Spezies-Reaktivität: human, mouse
658,00 €
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Tropicamide
Tropicamide

Artikelnummer: Cay16606-5

Muscarinic receptors are G protein-coupled acetylcholine receptors that play diverse roles. Five subtypes (M1-5) have been identified, which preferentially couple to various effector systems based on their G protein interaction.Tropicamide is a muscarinic acetylcholine receptor (mAChR) antagonist (pKi = 7.2 in...
Schlagworte: Ro 1-7683, N-ethyl-alpha-(hydroxymethyl)-N-(4-pyridinylmethyl)-benzeneacetamide
Anwendung: Muscarinic cholinergic receptor antagonist
CAS 1508-75-4
MW: 284.4 D
ab 44,00 €
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