Zu "K04119" wurden 36 Artikel gefunden!
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CRT0036521
Artikelnummer: Cay36600-50
CRT0036521 is an inhibitor of prostaglandin F synthase, also known as aldo-keto reductase 1C3 (AKR1C3, IC50 = 0.013 µM). It is selective for prostaglandin F synthase/AKR1C3 over AKR1C1, AKR1C2, and AKR1C4 (IC50s = 20, >30, and >30 µM, respectively).Formal Name: 3-[(3,4-dihydro-2(1H)-isoquinolinyl)sulfonyl]-benzoic...
| Schlagworte: | 3-[(3,4-dihydro-2(1H)-isoquinolinyl)sulfonyl]-benzoic acid |
| Anwendung: | Prostaglandin F synthase/AKR1C3 inhibitor |
| CAS | 327092-81-9 |
| MW: | 317.4 D |
ab 44,00 €
Anti-AKR1C3, C-terminal
Artikelnummer: ARG63695.100
Protein function: Catalyzes the conversion of aldehydes and ketones to alcohols. Catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ) and the oxidation of 9-alpha,11-beta- PGF2 to PGD2. Functions as a bi-directional 3-alpha-, 17-beta- and 20-alpha HSD. Can interconvert active...
| Schlagworte: | Anti-DD3, Anti-DD-3, Anti-DDH1, Anti-PGFS, Anti-HA1753, Anti-AKR1C3, EC=1.-.-.-, EC=1.3.1.20, EC=1.1.1.64, EC=1.1.1.112,... |
| Anwendung: | ELISA, WB |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
871,00 €
Prostaglandin F Synthase (human, recombinant)
Artikelnummer: Cay10007940-100
Human prostaglandin F synthase (PGFS) is a ~37 kDa monomeric protein with high sequence similarity to aldo-keto reductase family members. It exhibits two related primary activities, catalyzing the isomerization of PGH2 to PGF2alpha (PGH2 9,11-endoperoxide reductase activity), as well as the formation of...
| Schlagworte: | DD3, DD3, DDH1, DD-3, DD-3, AKR1C3, HA1753, HA1753, 17-beta-HSD 5, 17-beta-HSD 5, 3-alpha-HSD type 2, 3-alpha-HSD type 2,... |
| Anwendung: | Enzyme activity, WB |
| MW: | 37 kD |
687,00 €
Anti-AKR1C3
Artikelnummer: NSJ-R33228-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Aldo-keto reductase family 1, member C3 Protein function: Catalyzes the conversion of aldehydes and ketones to alcohols. Catalyzes the reduction of prostaglandin (PG) D2, PGH2 and...
| Schlagworte: | Anti-DD3, Anti-DD-3, Anti-DDH1, Anti-PGFS, Anti-HA1753, Anti-AKR1C3, EC=1.-.-.-, EC=1.1.1.64, EC=1.3.1.20, EC=1.1.1.239,... |
| Anwendung: | WB, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
836,00 €
ASP9521
Artikelnummer: Cay27308-10
ASP9521 is an inhibitor of 17beta-hydroxysteroid dehydrogenase type 5/aldo-keto reductase 1C3 (17beta-HSD5/AKR1C3, IC50 = 120 nM). It is selective for 17beta-HSD5/AKR1C3 over AKR1C2 (IC50 = 20 µM). ASP9521 inhibits conversion of androstenedione into testosterone by 17beta-HSD5/AKR1C3 (IC50s = 11 and 49 nM for human...
| Schlagworte: | [4-(2-hydroxy-2-methylpropyl)-1-piperidinyl](5-methoxy-1H-indol-2-yl)-methanone |
| Anwendung: | 17beta-HSD5/AKR1C3 inhibitor |
| CAS | 1126084-37-4 |
| MW: | 330.4 D |
ab 93,00 €
Aldo-keto reductase family 1 member C3 (AKR1C3), human,...
Artikelnummer: CSB-EP001544HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-323aa. Protein Length: Full Length. Tag Info: N-terminal GST-tagged. Target Protein Sequence: MDSKHQCVKL NDGHFMPVLG FGTYAPPEVP RSKALEVTKL AIEAGFRHID SAHLYNNEEQ VGLAIRSKIA DGSVKREDIF YTSKLWSTFH RPELVRPALE NSLKKAQLDY VDLYLIHSPM SLKPGEELSP TDENGKVIFD...
| Schlagworte: | DD3, DDH1, DD-3, PGFS, HA1753, AKR1C3, 17-beta-HSD 5, 3-alpha-HSD type 2, Prostaglandin F synthase, 3-alpha-HSD type II,... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 63.9 kD |
ab 219,00 €
Aldo-keto reductase family 1 member C3 (AKR1C3), human,...
Artikelnummer: CSB-EP001544HUc7.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-323aa. Protein Length: Full Length. Tag Info: C-terminal 6xHis-tagged. Target Protein Sequence: MDSKHQCVKL NDGHFMPVLG FGTYAPPEVP RSKALEVTKL AIEAGFRHID SAHLYNNEEQ VGLAIRSKIA DGSVKREDIF YTSKLWSTFH RPELVRPALE NSLKKAQLDY VDLYLIHSPM SLKPGEELSP...
| Schlagworte: | DD3, DDH1, DD-3, PGFS, HA1753, AKR1C3, 17-beta-HSD 5, 3-alpha-HSD type 2, Prostaglandin F synthase, 3-alpha-HSD type II,... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 43.8 kD |
ab 219,00 €
AKR1C3-IN-1
Artikelnummer: TGM-T7406-100mg
Description: AKR1C3-IN-1 is a potent and selective inhibitor of AKR1C3(IC50 of 13 nM). Target: Dehydrogenase, NADPH. Smiles: OC(=O)c1cccc(c1)S(=O)(=O)N1CCc2ccccc2C1. References: Jamieson S M F , Brooke D G , Heinrich D , et al. 3-(3,4-Dihydroisoquinolin-2(1 H )-ylsulfonyl)benzoic Acids: Highly Potent and Selective...
| Anwendung: | Prostaglandin F synthase/AKR1C3 inhibitor |
| CAS | 327092-81-9 |
| MW: | 317.36 D |
ab 30,00 €
AKR1C3 Protein, Human, Recombinant (His)
Artikelnummer: TGM-TMPJ-00962-10ug
Description: AKR1C3, is an enzyme which belongs to the aldo/keto reductase family. It is expressed in many tissues including adrenal gland, brain, kidney, liver, lung, mammary gland, placenta, small intestine, colon, spleen, prostate and testis. AKR1C3 catalyzes the conversion of aldehydes and ketones to alcohols....
| Schlagworte: | 3-alpha-HSD Type II Brain, 17-beta-HSD 5, 17-Beta-HSD 5, 3-Alpha-HSD Type 2, 17-beta-Hydroxysteroid Dehydrogenase Type 5,... |
| MW: | 38 kD |
ab 172,00 €
NEU
Human AKR1C3 (Aldo-keto Reductase Family 1 Member C3)...
Artikelnummer: G-AEKE03199.96
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human AKR1C3. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human AKR1C3....
| Schlagworte: | HA1753, AKR1C3, Prostaglandin F synthase, 3-alpha-HSD type II, brain, Dihydrodiol dehydrogenase 3, Dihydrodiol... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
694,00 €
NEU
Anti-AKR1C3 [R08-8G6] Monoclonal Antibody
Artikelnummer: G-AGMB01427.20
AKR1C3 Monoclonal Antibody from Assay Genie is a high quality antibody for research use only. Protein Function: Cytosolic aldo-keto reductase that catalyzes the NADH and NADPH-dependent reduction of ketosteroids to hydroxysteroids. Acts as a NAD(P)(H)-dependent 3-, 17- and 20-ketosteroid reductase on the steroid...
| Schlagworte: | Anti-HA1753, Anti-AKR1C3, Anti-Prostaglandin F synthase, Anti-3-alpha-HSD type II, brain, Anti-Dihydrodiol dehydrogenase... |
| Anwendung: | WB, ICC/IF, FC, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
134,00 €
NEU
AKR1C3 Protein, Human, Recombinant (His)
Artikelnummer: TGM-TMPJ-00962-100ug
Description: AKR1C3, is an enzyme which belongs to the aldo/keto reductase family. It is expressed in many tissues including adrenal gland, brain, kidney, liver, lung, mammary gland, placenta, small intestine, colon, spleen, prostate and testis. AKR1C3 catalyzes the conversion of aldehydes and ketones to alcohols....
| Schlagworte: | 3-Alpha-HSD Type 2 , 3-alpha-HSD Type II Brain , 17-beta-HSD 5 , Aldo-Keto Reductase Family 1 Member C3 ,... |
| MW: | 38 kD |
ab 105,00 €