Zu "K04010" wurden 139 Artikel gefunden!
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Avacopan
Artikelnummer: TGM-T8223-10mg
Description: Avacopan (CCX168) is an orally administered small-molecule C5aR ( IC50 : 0.1 nM.)antagonist that blocks the effects of C5a and prevents the development of GN induced by anti-myeloperoxidase antibodies in a murine model of AAV. Target: Complement System. Smiles:...
| Schlagworte: | CCX168 |
| Anwendung: | Targets C5a anaphylatoxin chemotactic receptor 1 (C5AR1, CD88) |
| CAS | 1346623-17-3 |
| MW: | 581.64 D |
ab 34,00 €
PMX-53 TFA
Artikelnummer: TGM-T83669-10mg
Description: PMX-53, a macrocyclic complement 5a (C5a) peptidomimetic and C5a receptor antagonist (IC50 = 0.3 µM), effectively inhibits the C5a-induced secretion of myeloperoxidase (MPO) in isolated human polymorphonuclear leukocytes (PMNs). Administered orally at 10 mg/kg, PMX-53 mitigates vascular leakage, PMN...
| Schlagworte: | AcPhe-[Orn-Pro-D-Cyclohexylalanine-Trp-Arg], 3D53, AcF-[OPdChaWR] |
| Anwendung: | C5a receptor antagonist |
| CAS | 514814-99-4 |
| MW: | 896.09 D |
ab 148,00 €
C5AR1 Protein-VLP, Human, Recombinant (His)
Artikelnummer: TGM-TMPH-01022-100ug
Description: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation...
| Schlagworte: | C5AR1, C5a-R, C5R1, C5a anaphylatoxin chemotactic receptor, C5AR, C5a anaphylatoxin chemotactic receptor 1, CD88 |
| MW: | 41.1 kD |
ab 930,00 €
C5AR1 Protein, Human, Recombinant (Cell-Free, His)
Artikelnummer: TGM-TMPH-01023-100ug
Description: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation...
| Schlagworte: | C5a-R, C5R1, C5a anaphylatoxin chemotactic receptor 1, C5AR1, C5a anaphylatoxin chemotactic receptor, C5AR, CD88 |
| MW: | 40.7 kD |
ab 1.982,00 €
W-54011
Artikelnummer: TGM-T17250-100mg
Description: W-54011 is a potent non-peptide C5a receptor antagonist. W-54011 inhibits the binding of 125I-labeled C5a to human neutrophils (Ki = 2.2 nM). W-54011 inhibits C5a-induced intracellular Ca2+ mobilization, chemotaxis, and generation of ROS in human neutrophils (IC50s = 3.1 nM, 2.7 nM, and 1.6 nM,...
| Anwendung: | C5a Receptor Antagonist |
| CAS | 405098-33-1 |
| MW: | 493.08 D |
ab 77,00 €
Human C5AR1 Protein, hFc Tag
Artikelnummer: DIM-PME100830.10
Recombinant Human C5AR1 Protein with C-terminal human Fc tag. C5AR1(Met1-Asp37) hFc(Glu99-Ala330), Protein function: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a (PubMed:1847994, PubMed:8182049, PubMed:7622471, PubMed:9553099, PubMed:10636859, PubMed:15153520, PubMed:29300009). The ligand...
| Schlagworte: | C5A, C5AR, C5R1, CD88 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 30.4 kD |
ab 148,00 €
C5AR1 (human) full length protein-synthetic nanodisc
Artikelnummer: DIM-FLP100086.10
Discover a breakthrough in membrane protein research and drug development with DIMA Biotech's Synthetic Nanodiscs. Traditional methods struggle with challenges in obtaining water-soluble and bioactive forms of multi-transmembrane proteins. Our innovative polymer-based Nanodisc platform offers a game-changing...
| Schlagworte: | C5AR, C5aR, CD88, C5a-R, C5AR1, C5a anaphylatoxin chemotactic receptor, C5a anaphylatoxin chemotactic receptor 1, C5A,... |
| Anwendung: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 39.3 kD |
ab 1.291,00 €
Anti-C5AR1
Artikelnummer: CSB-PA001479.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-CD88, Anti-C5aR, Anti-C5AR, Anti-C5a-R, Anti-C5AR1, Anti-C5a anaphylatoxin chemotactic receptor, Anti-C5a... |
| Anwendung: | ELISA, WB, IHC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 126,00 €
C5a anaphylatoxin chemotactic receptor (C5AR1), partial,...
Artikelnummer: CSB-EP003996HU1-B.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-37aa. Protein Length: Partial. Tag Info: N-terminal MBP-tagged and C-terminal 6xHis-Avi-tagged. Target Protein Sequence: MDSFNYTTPD YGHYDDKDTL DLNTPVDKTS NTLRVPD. Purity: Greater than 90% as determined by SDS-PAGE. Endotoxin: n/a. Biological...
| Schlagworte: | C5AR, C5aR, CD88, C5AR1, C5a-R, C5a anaphylatoxin chemotactic receptor, C5a anaphylatoxin chemotactic receptor 1,... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 52.1 kD |
ab 439,00 €
C5a anaphylatoxin chemotactic receptor (C5AR1), partial,...
Artikelnummer: CSB-EP003996HU1.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-37aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-KSI-tagged. Target Protein Sequence: MDSFNYTTPD YGHYDDKDTL DLNTPVDKTS NTLRVPD. Purity: Greater than 95% as determined by SDS-PAGE. Endotoxin: n/a. Biological Activity: n/a. Form: Liquid or...
| Schlagworte: | C5AR, C5aR, CD88, C5AR1, C5a-R, C5a anaphylatoxin chemotactic receptor, C5a anaphylatoxin chemotactic receptor 1,... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 19.6 kD |
ab 292,00 €
C5a anaphylatoxin chemotactic receptor (C5ar1), partial,...
Artikelnummer: CSB-EP003996MO1-B.1
Organism: Mus musculus (Mouse). Source: E.coli. Expression Region: 306-351aa. Protein Length: Partial. Tag Info: N-terminal MBP-tagged and C-terminal 6xHis-Avi-tagged. Target Protein Sequence: QGFHGRLLRS LPSIIRNALS EDSVGRDSKT FTPSTTDTST RKSQAV. Purity: Greater than 95% as determined by SDS-PAGE. Endotoxin: n/a....
| Schlagworte: | C5ar, C5aR, CD88, C5ar1, C5a-R, C5a anaphylatoxin chemotactic receptor, C5a anaphylatoxin chemotactic receptor 1,... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | mouse |
| MW: | 52.8 kD |
ab 395,00 €
C5a anaphylatoxin chemotactic receptor (C5ar1), partial,...
Artikelnummer: CSB-EP003996MO1.1
Organism: Mus musculus (Mouse). Source: E.coli. Expression Region: 306-351aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-KSI-tagged. Target Protein Sequence: QGFHGRLLRS LPSIIRNALS EDSVGRDSKT FTPSTTDTST RKSQAV. Purity: Greater than 95% as determined by SDS-PAGE. Endotoxin: n/a. Biological Activity: Not Test....
| Schlagworte: | C5ar, C5aR, CD88, C5ar1, C5a-R, C5a anaphylatoxin chemotactic receptor, C5a anaphylatoxin chemotactic receptor 1,... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | mouse |
| MW: | 20.4 kD |
ab 247,00 €