Zu "K04010" wurden 154 Artikel gefunden!
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Anti-C5aR, Mouse, mAb 20/70
Artikelnummer: HYC-HM1076-100UG
Dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50. For functional studies, in vitro dilutions have to be optimized in user's experimental setting.
| Schlagworte: | Anti-C5ar1, Anti-C5a anaphylatoxin chemotactic receptor, Anti-C5a anaphylatoxin chemotactic receptor 1 |
| Anwendung: | FC, FA, IF |
| Spezies-Reaktivität: | mouse |
ab 139,00 €
Anti-C5aR, Mouse, mAb 10/92
Artikelnummer: HYC-HM1077-100UG
For immunohistology, Western-blotting-and flow cytometry, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50.
| Schlagworte: | Anti-C5ar1, Anti-C5a anaphylatoxin chemotactic receptor, Anti-C5a anaphylatoxin chemotactic receptor 1 |
| Anwendung: | FC, IHC-F, WB |
| Spezies-Reaktivität: | mouse |
ab 139,00 €
Anti-C5aR, Human, mAb S5/1
Artikelnummer: HYC-HM2094-100UG
For immunohistology, flow cytometry and Western blotting dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:10. For inhibition of binding of C5a to its receptor dilutions have to...
| Schlagworte: | Anti-C5AR1, Anti-C5a anaphylatoxin chemotactic receptor, Anti-C5a anaphylatoxin chemotactic receptor 1 |
| Anwendung: | FC, IHC-F, FA, IHC-P, WB |
| Spezies-Reaktivität: | human |
ab 139,00 €
Anti-C5aR, Human, mAb W17/1
Artikelnummer: HYC-HM2095-100UG
For immunohistology and flow cytometry, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:10.
| Schlagworte: | Anti-C5AR1, Anti-C5a anaphylatoxin chemotactic receptor, Anti-C5a anaphylatoxin chemotactic receptor 1 |
| Anwendung: | FC, IHC-F, IHC-P |
| Spezies-Reaktivität: | human |
ab 139,00 €
Anti-C5aR, Rat, mAb R63
Artikelnummer: HYC-HM3017-100UG
For immunohistochemistry, flow cytometry and Western blotting, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50.
| Schlagworte: | Anti-C5ar1, Anti-C5a anaphylatoxin chemotactic receptor, Anti-C5a anaphylatoxin chemotactic receptor 1 |
| Anwendung: | FC, IHC-F, ELISA, IF, WB |
| Spezies-Reaktivität: | rat |
ab 139,00 €
Anti-C5aR1 Antibody (Avdoralimab)
Artikelnummer: BPS-83856-1
Anti-C5aR1 antibody, also known as Avdoralimab or IPH 5401, is a fully human IgGkappa monoclonal antibody that targets the complement C5a receptor 1 (C5aR1) and prevents its binding to C5a. It has studied in the context of complement-driven inflammatory diseases and solid tumours. Complement component 5a receptor 1...
| Schlagworte: | C5AR1, C5a anaphylatoxin chemotactic receptor 1, C5a anaphylatoxin chemotactic receptor |
| Anwendung: | ELISA, FC, FA |
| Wirt: | Human |
| Spezies-Reaktivität: | human |
ab 986,00 €
CHO-K1/C5a/Galpha15 Stable Cell Line
Artikelnummer: GSC-M00327
The complement component 5a receptor 1 (C5a) is Gq/11 and Gi/o-coupled GPCRs. C5a is a significant pathogenic driver in a number of immuno-inflammatory diseases, making C5a inhibition an attractive therapeutic strategy. C5a receptor plays an important role in mediating acute kidney allograft rejection.
| Schlagworte: | C5AR1, C5a anaphylatoxin chemotactic receptor, C5a anaphylatoxin chemotactic receptor 1 |
11.424,00 €
PMX-53 (trifluoroacetate salt)
Artikelnummer: Cay35840-10
PMX-53 is a macrocyclic complement 5a (C5a) peptidomimetic and an antagonist of the C5a receptor (IC50 = 0.3 µM). It inhibits C5a-induced secretion of myeloperoxidase (MPO) in isolated human polymorphonuclear leukocytes (PMNs). PMX-53 (10 mg/kg, p.o.) inhibits vascular leakage, PMN infiltration, and peritoneal...
| Schlagworte: | 3D53, AcF-[OPdChaWR], AcPhe-[Orn-Pro-D-Cyclohexylalanine-Trp-Arg], (6->2)-lactam,... |
| Anwendung: | C5a receptor antagonist |
| CAS | 514814-99-4 |
| MW: | 896.1 D |
ab 89,00 €
Avacopan
Artikelnummer: TGM-T8223-1mg
Description: Avacopan (CCX168) is an orally administered small-molecule C5aR ( IC50 : 0.1 nM.)antagonist that blocks the effects of C5a and prevents the development of GN induced by anti-myeloperoxidase antibodies in a murine model of AAV. Target: Complement System. Smiles:...
| Schlagworte: | CCX168 |
| Anwendung: | Targets C5a anaphylatoxin chemotactic receptor 1 (C5AR1, CD88) |
| CAS | 1346623-17-3 |
| MW: | 581.64 D |
ab 34,00 €
Anti-C5AR1, clone 10/92
Artikelnummer: ARG22558.100
Protein function: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N- terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor...
| Schlagworte: | Anti-C5aR, Anti-C5ar, Anti-CD88, Anti-C5ar1, Anti-C5a-R, Anti-C5a anaphylatoxin chemotactic receptor, Anti-C5a... |
| Anwendung: | FC, FA, IHC (frozen) |
| Wirt: | Rat |
| Spezies-Reaktivität: | mouse |
658,00 €
Anti-CD88 / C5aR, clone S5/1 (PE )
Artikelnummer: ARG54294.50
Protein function: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a (PubMed:1847994, PubMed:8182049, PubMed:7622471, PubMed:9553099, PubMed:10636859, PubMed:15153520). The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a...
| Schlagworte: | Anti-C5AR, Anti-CD88, Anti-C5aR, Anti-C5a-R, Anti-C5AR1, Anti-C5a anaphylatoxin chemotactic receptor, Anti-C5a... |
| Anwendung: | FC, IP, WB, IHC (paraffin) |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, bovine, ferret, rabbit |
551,00 €
L-156,602
Artikelnummer: Cay23896-2.5
L-156,602 is an antagonist of the complement component 5A (C5a) receptor (IC50 = 1.7 µg/L in a radioligand binding assay using neutrophil membranes). It is also a cyclic depsipeptide antibiotic that is active against Gram-positive bacteria. L-156,602 has anti-inflammatory activity in mice, decreasing inflammation...
| Schlagworte: | PD 124966,... |
| Anwendung: | C5a receptor antagonist |
| CAS | 125228-51-5 |
| MW: | 841 D |
ab 333,00 €