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Zu "K03875" wurden 39 Artikel gefunden!
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Artikelnummer: ELK-ELK4585.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human SKP2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human SKP2. Next,...
Schlagworte: | SKP2, FBXL1, p45skp2, F-box protein Skp2, F-box/LRR-repeat protein 1, S-phase kinase-associated protein 2,... |
Anwendung: | ELISA |
Spezies-Reaktivität: | human |
ab 365,00 €
Artikelnummer: Cay26141-5
SKPin C1 is an inhibitor of Skp1-Cullin1-F-box (SCF) family protein Skp2-mediated p27 degradation. It binds to Skp2 at the Cdc kinase subunit 1 (Cks1) interaction interface and blocks ubiquitylation of p27 in a Cks1-dependent manner in vitro when used at a concentration of 50 µM. SKPin C1 increases nuclear...
Schlagworte: | 2-[4-bromo-2-[[4-oxo-3-(3-pyridinylmethyl)-2-thioxo-5-thiazolidinylidene]methyl]phenoxy]-acetic acid |
Anwendung: | Skp2-mediated p27 degradation inhibitor |
CAS | 432001-69-9 |
MW: | 465.3 D |
ab 110,00 €
Artikelnummer: A302-436A
Protein function: Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription. Specifically recognizes...
Schlagworte: | Anti-SKP2, Anti-FBXL1, Anti-p45skp2, Anti-F-box protein Skp2, Anti-F-box/LRR-repeat protein 1, Anti-S-phase... |
Anwendung: | WB, IP |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 164,00 €
Artikelnummer: A302-437A
Protein function: Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription. Specifically recognizes...
Schlagworte: | Anti-SKP2, Anti-FBXL1, Anti-p45skp2, Anti-F-box protein Skp2, Anti-F-box/LRR-repeat protein 1, Anti-S-phase... |
Anwendung: | WB, IP |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 164,00 €
Artikelnummer: G-HUFI02167.96
Anwendung: | ELISA |
Spezies-Reaktivität: | human |
641,00 €
Artikelnummer: NSJ-R30268
0.5mg/ml if reconstituted with 0.2ml sterile DI water. The F box protein Skp2(S-phase kinase-associated protein 2) is oncogenic, and its frequent amplification and overexpression correlate with the grade of malignancy of certain tumors. Skp2 controls p300-p53 signaling pathways in cancer cells, making it a potential...
Schlagworte: | Anti-SKP2, Anti-FBXL1, Anti-p45skp2, Anti-F-box protein Skp2, Anti-F-box/LRR-repeat protein 1, Anti-S-phase... |
Anwendung: | WB, IHC (paraffin) |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
755,00 €
Artikelnummer: NSJ-RQ4170
0.5mg/ml if reconstituted with 0.2ml sterile DI water. The F box protein Skp2 (S-phase kinase-associated protein 2) is oncogenic, and its frequent amplification and overexpression correlate with the grade of malignancy of certain tumors. Skp2 controls p300-p53 signaling pathways in cancer cells, making it a...
Schlagworte: | Anti-SKP2, Anti-FBXL1, Anti-p45skp2, Anti-F-box protein Skp2, Anti-F-box/LRR-repeat protein 1, Anti-S-phase... |
Anwendung: | WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
755,00 €
Artikelnummer: NSJ-F51164-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. SKP2 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in...
Schlagworte: | Anti-SKP2, Anti-FBXL1, Anti-p45skp2, Anti-F-box protein Skp2, Anti-F-box/LRR-repeat protein 1, Anti-S-phase... |
Anwendung: | WB, FC, ELISA |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 326,00 €
Artikelnummer: E-AB-62215.120
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The...
Schlagworte: | Anti-SKP2, Anti-FBXL1, Anti-p45skp2, Anti-F-box protein Skp2, Anti-F-box/LRR-repeat protein 1, Anti-S-phase... |
Anwendung: | WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
ab 198,00 €
Artikelnummer: ABE-35-1868-50
Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription. Specifically recognizes phosphorylated...
Schlagworte: | Anti-SKP2, Anti-FBXL1, Anti-p45skp2, Anti-F-box protein Skp2, Anti-F-box/LRR-repeat protein 1, Anti-S-phase... |
Anwendung: | WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
574,00 €
Artikelnummer: Cay26142-10
SZL P1-41 is an inhibitor of the Skp1-Cullin1-F-box (SCF) family protein Skp2. It inhibits the interaction between Skp2 and Skp1 to block Skp2 E3 ubiquitin ligase activity when used at a concentration of 5 µM. SZL P1-41 selectively inhibits Skp2 over Fbw7 and beta-TrCP E3 ubiquitin ligase activity in HEK293T cells....
Schlagworte: | 3-(2-benzothiazolyl)-6-ethyl-7-hydroxy-8-(1-piperidinylmethyl)-4H-1-benzopyran-4-one |
Anwendung: | Skp2 (FBXL1) inhibitor |
CAS | 222716-34-9 |
MW: | 420.5 D |
ab 158,00 €
Artikelnummer: ARG54932.100
Protein function: Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription. Specifically recognizes...
Schlagworte: | Anti-SKP2, Anti-FBXL1, Anti-p45skp2, Anti-F-box protein Skp2, Anti-F-box/LRR-repeat protein 1, Anti-S-phase... |
Anwendung: | FC, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
624,00 €