Zu "K03871" wurden 81 Artikel gefunden!
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Anti-VHL Biotin Conjugate
Artikelnummer: NSJ-R35773BTN
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Von Hippel-Lindau tumor suppressor, VHL1
| Schlagworte: | Anti-VHL, Anti-pVHL, Anti-Protein G7, Anti-von Hippel-Lindau disease tumor suppressor, VHL Antibody Biotin Conjugate |
| Anwendung: | WB, ELISA (peptide), EIA |
| Wirt: | Goat |
| Spezies-Reaktivität: | human, mouse, rat |
836,00 €
CM11
Artikelnummer: Cay41885-10
A PROTAC that drives VHL degradation, selectively induces the degradation of pVHL30 over pVHL19 and a panel of 6,449 proteins in HeLa cells at 1 µM but does decrease protein levels of Cul-2. Formulation: A solid. InChI:...
| Schlagworte: | (4R,4'R)-1,1'-(1,20-dioxo-3,6,9,12,15,18-hexaoxaeicosane-1,20-diyl)bis[3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazo... |
| Anwendung: | VHL degrading PROTAC |
| CAS | 2244684-49-7 |
| MW: | 1179.5 D |
ab 147,00 €
VH298
Artikelnummer: Cay21133-1
VH298 is a cell-permeant inhibitor of von Hippel-Lindau disease tumor suppressor (VHL, Kd = 90 nM by isothermal titration calorimetry). VHL is a component of the complex that polyubiquitinates hydroxylated hypoxia-inducible factor-alpha (HIF-alpha) isoforms leading to proteasomal degradation. Through its effects on...
| Schlagworte: | (2S,4R)-1-((S)-2-(1-cyanocyclopropane-1-carboxamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyr... |
| Anwendung: | Cell-permeant VHL inhibitor |
| CAS | 2097381-85-4 |
| MW: | 523.7 D |
ab 56,00 €
VHL Ligand 1 (hydrochloride)
Artikelnummer: Cay21591-10
VHL ligand 1 is a building block in the synthesis of proteolysis-targeting chimera technologies (PROTACs). It is the von Hippel-Lindau (VHL) E3 ligase binding portion of some VHL-based PROTACs, including BET PROTAC MZ1 (Cay-21622).Formal Name:...
| Schlagworte: | (4R)-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-L-prolinamide, monohydrochloride |
| Anwendung: | Building block, PROTAC |
| CAS | 1448189-80-7 |
| MW: | 467 D |
ab 108,00 €
VHL Protein, Human, Recombinant (His & Avi)
Artikelnummer: TGM-TMPY-06026-100ug
Description: VHL Protein, Human, Recombinant (His & Avi) is expressed in E. coli expression system with His and Avi tag. The predicted molecular weight is 27.5 kDa and the accession number is A0A024R2F2.
| Schlagworte: | RCA1, HRCA1, VHL1, von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase, pVHL |
| MW: | 27.5 kD |
ab 280,00 €
Anti-VHL, Internal
Artikelnummer: ARG64033.100
Protein function: Involved in the ubiquitination and subsequent proteasomal degradation via the von Hippel-Lindau ubiquitination complex. Seems to act as target recruitment subunit in the E3 ubiquitin ligase complex and recruits hydroxylated hypoxia- inducible factor (HIF) under normoxic conditions. Involved in...
| Schlagworte: | Anti-VHL, Anti-pVHL, Anti-Protein G7, Anti-Von Hippel-Lindau disease tumor suppressor |
| Anwendung: | ELISA, WB |
| Wirt: | Goat |
| Spezies-Reaktivität: | human, mouse, rat |
871,00 €
Human Von Hippel Lindau / VHL ELISA Kit
Artikelnummer: G-HUFI01668.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
698,00 €
Anti-VHL
Artikelnummer: NSJ-R35773-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Von Hippel-Lindau tumor suppressor, VHL1 Protein function: Involved in the ubiquitination and subsequent proteasomal degradation via the von Hippel-Lindau ubiquitination complex. Seems to act as...
| Schlagworte: | Anti-VHL, Anti-pVHL, Anti-Protein G7, Anti-Von Hippel-Lindau disease tumor suppressor, VHL Antibody |
| Anwendung: | WB, ELISA (peptide), EIA |
| Wirt: | Goat |
| Spezies-Reaktivität: | human, mouse, rat |
836,00 €
Anti-VHL
Artikelnummer: E-AB-10671.120
Von Hippel-Lindau syndrome (VHL) is a dominantly inherited familial cancer syndrome predisposing to a variety of malignant and benign tumors. A germline mutation of this gene is the basis of familial inheritance of VHL syndrome. The protein encoded by this gene is a component of the protein complex that includes...
| Schlagworte: | Anti-VHL, Anti-pVHL, Anti-Protein G7, Anti-von Hippel-Lindau disease tumor suppressor, VHL Polyclonal Antibody |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 89,00 €
Anti-VHL
Artikelnummer: NSJ-F49682-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. Von Hippel-Lindau syndrome (VHL) is a dominantly inherited familial cancer syndrome predisposing to a variety of malignant and benign tumors. A germline mutation of VHL gene is the basis of familial inheritance of VHL syndrome. The protein is a component of the protein...
| Schlagworte: | Anti-VHL, Anti-pVHL, Anti-Protein G7, Anti-Von Hippel-Lindau disease tumor suppressor, VHL Antibody |
| Anwendung: | IHC, FC, WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 361,00 €
VH 032 Linker 3 (hydrate)
Artikelnummer: Cay26151-1
VH 032 linker 3 is a derivative of the proteolysis-targeting chimera technology (PROTAC) building block VHL ligand 1 (Cay-21591).Formal Name: (4R)-N-(5-amino-1-oxopentyl)-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-L-prolinamide, dihydrochloride, hydrate. Molecular Formula: C27H39N5O4S ....
| Schlagworte: | (4R)-N-(5-amino-1-oxopentyl)-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-L-prolinamide,... |
| Anwendung: | Building block, PROTAC |
| MW: | 602.6 D |
ab 49,00 €
VH 032 Linker 2
Artikelnummer: Cay26149-10
VH 032 Linker 2 is a derivative of the proteolysis-targeting chimera technology (PROTAC) building block VHL ligand 1 (Cay-21591). VH 032 Linker 2 comprises the von Hippel-Lindau (VHL) ligand domain and the polyethylene glycol (PEG) linker of the bromodomain and extra terminal (BET) inhibitor-containing PROTACs MZ2...
| Schlagworte: | E3 Ligase Ligand-Linker Conjugate 7,... |
| Anwendung: | Building block, PROTAC |
| CAS | 2064292-52-8 |
| MW: | 700.3 D |
ab 85,00 €