Zu "K03871" wurden 57 Artikel gefunden!

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Rat vHL (Von Hippel Lindau Tumor Suppressor) ELISA Kit
Rat vHL (Von Hippel Lindau Tumor Suppressor) ELISA Kit

Artikelnummer: ELK-ELK6800.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat vHL. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat vHL. Next, Avidin...
Schlagworte: Vhl, pVHL, von Hippel-Lindau disease tumor suppressor
Anwendung: ELISA
Spezies-Reaktivität: rat
365,00 € ab 328,50 €
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VH 032 Linker 6
VH 032 Linker 6

Artikelnummer: Cay38898-10

VH 032 linker 6 is a precursor in the synthesis of proteolysis-targeting chimeras (PROTACs) that contains a terminal alkyne conjugated via a PEG linker to VHL ligand 1 (Cay-21591), which binds to VHL E3 ligase. It has been used in the synthesis of PROTACs targeting Bcl-xL in senescent cells.Formal Name:...
Schlagworte: (4R)-3-methyl-N-[2-[2-[2-(2-propyn-1-yloxy)ethoxy]ethoxy]acetyl]-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]meth...
Anwendung: PROTAC precursor
CAS 2098799-80-3
MW: 614.8 D
ab 76,00 €
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VH298
VH298

Artikelnummer: Cay21133-1

VH298 is a cell-permeant inhibitor of von Hippel-Lindau disease tumor suppressor (VHL, Kd = 90 nM by isothermal titration calorimetry). VHL is a component of the complex that polyubiquitinates hydroxylated hypoxia-inducible factor-alpha (HIF-alpha) isoforms leading to proteasomal degradation. Through its effects on...
Schlagworte: (2S,4R)-1-((S)-2-(1-cyanocyclopropane-1-carboxamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyr...
Anwendung: Cell-permeant VHL inhibitor
CAS 2097381-85-4
MW: 523.7 D
ab 50,00 €
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VHL Ligand 1 (hydrochloride)
VHL Ligand 1 (hydrochloride)

Artikelnummer: Cay21591-10

VHL ligand 1 is a building block in the synthesis of proteolysis-targeting chimera technologies (PROTACs). It is the von Hippel-Lindau (VHL) E3 ligase binding portion of some VHL-based PROTACs, including BET PROTAC MZ1 (Cay-21622).Formal Name:...
Schlagworte: (4R)-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-L-prolinamide, monohydrochloride
Anwendung: Building block, PROTAC
CAS 1448189-80-7
MW: 467 D
ab 97,00 €
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Anti-VHL, Internal
Anti-VHL, Internal

Artikelnummer: ARG64033.100

Protein function: Involved in the ubiquitination and subsequent proteasomal degradation via the von Hippel-Lindau ubiquitination complex. Seems to act as target recruitment subunit in the E3 ubiquitin ligase complex and recruits hydroxylated hypoxia- inducible factor (HIF) under normoxic conditions. Involved in...
Schlagworte: Anti-VHL, Anti-pVHL, Anti-Protein G7, Anti-Von Hippel-Lindau disease tumor suppressor
Anwendung: ELISA, WB
Wirt: Goat
Spezies-Reaktivität: human, mouse, rat
784,00 €
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Human Von Hippel Lindau / VHL ELISA Kit
Human Von Hippel Lindau / VHL ELISA Kit

Artikelnummer: G-HUFI01668.96

Anwendung: ELISA
Spezies-Reaktivität: human
641,00 €
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Anti-VHL
Anti-VHL

Artikelnummer: NSJ-R35773-100UG

0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Von Hippel-Lindau tumor suppressor, VHL1 Protein function: Involved in the ubiquitination and subsequent proteasomal degradation via the von Hippel-Lindau ubiquitination complex. Seems to act as...
Schlagworte: Anti-VHL, Anti-pVHL, Anti-Protein G7, Anti-Von Hippel-Lindau disease tumor suppressor, VHL Antibody
Anwendung: WB, ELISA (peptide), EIA
Wirt: Goat
Spezies-Reaktivität: human, mouse, rat
755,00 €
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Anti-VHL
Anti-VHL

Artikelnummer: E-AB-10671.120

Von Hippel-Lindau syndrome (VHL) is a dominantly inherited familial cancer syndrome predisposing to a variety of malignant and benign tumors. A germline mutation of this gene is the basis of familial inheritance of VHL syndrome. The protein encoded by this gene is a component of the protein complex that includes...
Schlagworte: Anti-VHL, Anti-pVHL, Anti-Protein G7, Anti-von Hippel-Lindau disease tumor suppressor, VHL Polyclonal Antibody
Anwendung: IHC, ELISA
Wirt: Rabbit
Spezies-Reaktivität: human
ab 71,00 €
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Anti-VHL
Anti-VHL

Artikelnummer: NSJ-F49682-0.08ML

In 1X PBS, pH 7.4, with 0.09% sodium azide. Von Hippel-Lindau syndrome (VHL) is a dominantly inherited familial cancer syndrome predisposing to a variety of malignant and benign tumors. A germline mutation of VHL gene is the basis of familial inheritance of VHL syndrome. The protein is a component of the protein...
Schlagworte: Anti-VHL, Anti-pVHL, Anti-Protein G7, Anti-Von Hippel-Lindau disease tumor suppressor, VHL Antibody
Anwendung: IHC, FC, WB, ELISA
Wirt: Rabbit
Spezies-Reaktivität: human
ab 326,00 €
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VH 032 Linker 2
VH 032 Linker 2

Artikelnummer: Cay26149-10

VH 032 Linker 2 is a derivative of the proteolysis-targeting chimera technology (PROTAC) building block VHL ligand 1 (Cay-21591). VH 032 Linker 2 comprises the von Hippel-Lindau (VHL) ligand domain and the polyethylene glycol (PEG) linker of the bromodomain and extra terminal (BET) inhibitor-containing PROTACs MZ2...
Schlagworte: E3 Ligase Ligand-Linker Conjugate 7,...
Anwendung: Building block, PROTAC
CAS 2064292-52-8
MW: 700.3 D
ab 77,00 €
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VH 032 Linker 3 (hydrate)
VH 032 Linker 3 (hydrate)

Artikelnummer: Cay26151-1

VH 032 linker 3 is a derivative of the proteolysis-targeting chimera technology (PROTAC) building block VHL ligand 1 (Cay-21591).Formal Name: (4R)-N-(5-amino-1-oxopentyl)-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-L-prolinamide, dihydrochloride, hydrate. Molecular Formula: C27H39N5O4S ....
Schlagworte: (4R)-N-(5-amino-1-oxopentyl)-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-L-prolinamide,...
Anwendung: Building block, PROTAC
MW: 602.6 D
ab 43,00 €
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Anti-VHL
Anti-VHL

Artikelnummer: ARG58776.100

Protein function: Involved in the ubiquitination and subsequent proteasomal degradation via the von Hippel-Lindau ubiquitination complex. Seems to act as a target recruitment subunit in the E3 ubiquitin ligase complex and recruits hydroxylated hypoxia- inducible factor (HIF) under normoxic conditions. Involved in...
Schlagworte: Anti-VHL, Anti-pVHL, Anti-Protein G7, Anti-von Hippel-Lindau disease tumor suppressor
Anwendung: WB
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
624,00 €
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