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Zu "K03783" wurden 27 Artikel gefunden!
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Artikelnummer: Cay39609-1
Forodesine is a purine nucleoside derivative and purine nucleoside phosphorylase (PNP) inhibitor (IC50s = 1.19, 0.48, 1.24, 0.66, and 1.57 nM for human, mouse, rat, monkey, and dog PNP, respectively). It inhibits phytohemagglutinin A-, mixed lymphocyte reaction-, or IL-2-induced proliferation of isolated human...
Schlagworte: | 7-[(2S,3S,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-2-pyrrolidinyl]-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one,... |
Anwendung: | Nucleoside derivative, PNP (purine-nucleoside phosphorylase) inhibitor |
MW: | 339.2 D |
ab 35,00 €
Artikelnummer: Cay16381-5
7-methyl-6-Thioguanosine is a chromophoric substrate that is used to quantify inorganic phosphate (Pi). In the presence of purine nucleoside phosphorylase, it reacts with Pi to produce 7-methyl-6-thioguanine and ribose 1-phosphate, with the increase in 7-methyl-6-thioguanine followed by continuous spectrophotometry...
Schlagworte: | MESG, 2-amino-6,9-dihydro-7-methyl-9-beta-D-ribofuranosyl-6-thioxo-1H-purinium, inner salt |
Anwendung: | Chromophoric substrate, Inorganic phosphate quantification |
CAS | 55727-10-1 |
MW: | 313.3 D |
ab 141,00 €
Artikelnummer: Cay21674-10
9-Deazaguanine is an analog of guanine that acts as an inhibitor of purine nucleoside phosphorylase (PNP, Kd = 160 nM). Inhibitors of PNP are used to control T cell proliferation, particularly in T cell cancers, autoimmune diseases, and tissue transplant rejection.Formal Name:...
Schlagworte: | NSC 344522, 2-amino-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one |
Anwendung: | PNP inhibitor |
CAS | 65996-58-9 |
MW: | 150.1 D |
ab 84,00 €
Artikelnummer: ARG55593.100
Protein function: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. [The UniProt Consortium]
Schlagworte: | Anti-phospho-NP, Anti-phospho-PNP, EC=2.4.2.1, Anti-phospho-Inosine phosphorylase, Anti-phospho-Inosine-guanosine... |
Anwendung: | WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
584,00 €
Artikelnummer: A304-240A
Protein function: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. [The UniProt Consortium]
Schlagworte: | Anti-NP, Anti-PNP, EC=2.4.2.1, Anti-Inosine phosphorylase, Anti-Purine nucleoside phosphorylase, Anti-Inosine-guanosine... |
Anwendung: | WB, IP |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 164,00 €
Artikelnummer: NSJ-R35905-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Purine nucleoside phosphorylase Protein function: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside...
Schlagworte: | Anti-NP, Anti-PNP, EC=2.4.2.1, Anti-Inosine phosphorylase, Anti-Inosine-guanosine phosphorylase, Anti-Purine nucleoside... |
Anwendung: | WB, ELISA (peptide) |
Wirt: | Goat |
Spezies-Reaktivität: | human |
755,00 €
Artikelnummer: NSJ-R32597
0.5mg/ml if reconstituted with 0.2ml sterile DI water. The PNP gene encodes Purine nucleoside phosphorylase, an enzyme that catalyzes the reversible phosphorolysis of the purine nucleosides and deoxynucleosides inosine, guanosine, deoxyinosine, and deoxyguanosine. It is presented results from gene dosage studies...
Schlagworte: | Anti-NP, Anti-PNP, Anti-Inosine phosphorylase, Anti-Inosine-guanosine phosphorylase, Anti-Purine nucleoside phosphorylase,... |
Anwendung: | WB, IHC (paraffin), FC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
755,00 €
Artikelnummer: E-AB-66202.120
This gene encodes an enzyme which reversibly catalyzes the phosphorolysis of purine nucleosides. The enzyme is trimeric, containing three identical subunits. Mutations which result in nucleoside phosphorylase deficiency result in defective T-cell (cell-mediated) immunity but can also affect B-cell immunity and...
Schlagworte: | Anti-NP, Anti-PNP, EC=2.4.2.1, Anti-Inosine phosphorylase, Anti-Inosine-guanosine phosphorylase, Anti-Purine nucleoside... |
Anwendung: | IF |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse |
ab 198,00 €
Artikelnummer: G-CAB14032.100
WB 1:500 - 1:2000, IF 1:50 - 1:200. Protein function: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. [The UniProt Consortium]
Schlagworte: | Anti-NP, Anti-PNP, EC=2.4.2.1, Anti-Inosine phosphorylase, Anti-Purine nucleoside phosphorylase, Anti-Inosine-guanosine... |
Anwendung: | WB, IF |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse |
ab 352,00 €
Artikelnummer: G-CAB5778.100
Anwendung: | IHC, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
ab 352,00 €
Artikelnummer: G-CAB19885.100
Protein function: Catalyzes the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (PubMed:9305964, PubMed:23438750). Preferentially acts on 6-oxopurine nucleosides including inosine and...
Schlagworte: | Anti-NP, Anti-PNP, Anti-Inosine phosphorylase, Anti-Purine nucleoside phosphorylase, Anti-Inosine-guanosine phosphorylase,... |
Anwendung: | WB, IF |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse |
ab 352,00 €
Artikelnummer: G-CAB19886.100
Protein function: Catalyzes the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (PubMed:9305964, PubMed:23438750). Preferentially acts on 6-oxopurine nucleosides including inosine and...
Schlagworte: | Anti-NP, Anti-PNP, Anti-Inosine phosphorylase, Anti-Purine nucleoside phosphorylase, Anti-Inosine-guanosine phosphorylase,... |
Anwendung: | WB, IP |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse |
ab 352,00 €