Zu "K03728" wurden 36 Artikel gefunden!
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Anti-NR1D1 / Nuclear receptor subfamily 1 group D member 1
Artikelnummer: NSJ-FY12968
Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml. NR1D1 antibody detects Nuclear receptor subfamily 1 group D member 1, a transcriptional repressor that plays an essential role in circadian rhythm regulation, lipid metabolism, and inflammation. The UniProt recommended name is Nuclear receptor...
| Schlagworte: | Anti-NR1D1, Anti-Rev-erbA-alpha, Anti-V-erbA-related protein 1, Anti-Nuclear receptor subfamily 1 group D member 1, NR1D1... |
| Anwendung: | WB, IHC, FC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
SR8278
Artikelnummer: Cay17000-1
REV-ERBalpha is a nuclear receptor and transcription repressor that coordinates circadian rhythm and metabolic pathways in a heme-dependent manner. SR8278 is an antagonist of REV-ERBalpha (EC50 = 0.47 µM), blocking activation of the receptor by the synthetic agonist GSK 4112 (Cay-11931). Moreover, SR8278 stimulates...
| Schlagworte: | 1,2,3,4-tetrahydro-2-[[5-(methylthio)-2-thienyl]carbonyl]-3-isoquinolinecarboxylic acid, ethyl ester |
| Anwendung: | NR1D1 antagonist |
| CAS | 1254944-66-5 |
| MW: | 361.5 D |
ab 67,00 €
GSK4112
Artikelnummer: Cay11931-5
REV-ERBalpha is a nuclear hormone receptor with roles in circadian rhythm, adipogenesis, lipid metabolism, and inflammation. It binds porphoryin heme and in response to fluctuations in heme levels in cells it recruits corepressors such as NCoR and HDAC3 to repress the transcription of key genes involved in metabolic...
| Schlagworte: | N-[(4-chlorophenyl)methyl]-N-[(5-nitro-2-thienyl)methyl]-glycine, 1,1-dimethylethyl ester |
| Anwendung: | Metabolic/circadian pathway studies |
| CAS | 1216744-19-2 |
| MW: | 396.9 D |
ab 97,00 €
SR9011
Artikelnummer: Cay11930-1
SR9011 is a REV-ERB agonist that increases the constitutive repression of genes regulated by REV-ERBalpha and REV-ERBbeta with IC50 values of 790 and 560 nM, respectively. It has no activity at other nuclear receptors. SR9011 blocks the activity of the suprachiasmatic nucleus (SCN) clock, with reversible inhibition...
| Schlagworte: | 3-[[[(4-chlorophenyl)methyl][(5-nitro-2-thienyl)methyl]amino]methyl]-N-pentyl-1-pyrrolidinecarboxamide |
| Anwendung: | REV-ERB agonist |
| CAS | 1379686-29-9 |
| MW: | 479 D |
ab 139,00 €
Anti-NR1D1
Artikelnummer: E-AB-11449.120
This gene encodes a transcription factor that is a member of the nuclear receptor subfamily 1. The encoded protein is a ligand-sensitive transcription factor that negatively regulates the expression of core clock proteins. In particular this protein represses the circadian clock transcription factor aryl hydrocarbon...
| Schlagworte: | Anti-EAR1, Anti-EAR-1, Anti-NR1D1, Anti-Rev-erbA-alpha, Anti-V-erbA-related protein 1, Anti-Nuclear receptor subfamily 1... |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 89,00 €
Anti-NR1D1
Artikelnummer: ATA-HPA007935.100
Protein function: Transcriptional repressor which coordinates circadian rhythm and metabolic pathways in a heme-dependent manner. Integral component of the complex transcription machinery that governs circadian rhythmicity and forms a critical negative limb of the circadian clock by directly repressing the...
| Schlagworte: | Anti-EAR1, Anti-EAR-1, Anti-NR1D1, Anti-Rev-erbA-alpha, Anti-V-erbA-related protein 1, Anti-Nuclear receptor subfamily 1... |
| Anwendung: | IHC, ICC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 330,00 €
Human NR1D1 (Nuclear Receptor Subfamily 1, Group D,...
Artikelnummer: ELK-ELK5412.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human NR1D1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human NR1D1. Next,...
| Schlagworte: | EAR1, EAR-1, NR1D1, Rev-erbA-alpha, V-erbA-related protein 1, Nuclear receptor subfamily 1 group D member 1 |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 374,00 €
Anti-NR1D1
Artikelnummer: CSB-PA099477.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: NR1D1. Antigen Species: Human
| Schlagworte: | Anti-EAR1, Anti-EAR-1, Anti-NR1D1, Anti-Rev-erbA-alpha, Anti-V-erbA-related protein 1, Anti-Nuclear receptor subfamily 1... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 167,00 €
SR9011
Artikelnummer: TGM-T3688-10mg
Description: SR9011 is a REV-ERB agonist (IC50: 790 nM, REV-ERBalpha, IC50: 560 nM, REV-ERBbeta). Target: Autophagy. Smiles: CCCCCNC(=O)N1CCC(CN(Cc2ccc(s2)[N+]([O-])=O)Cc2ccc(Cl)cc2)C1. References: Solt LA, et al. Nature. 2012 Mar 29,485(7396):62-8.
| Anwendung: | REV-ERB agonist |
| CAS | 1379686-29-9 |
| MW: | 479.04 D |
ab 50,00 €
SR8278
Artikelnummer: TGM-T7837-10mg
Description: SR8278 is an REV-ERBalpha antagonist(EC50 = 0.47 µM), blocking activation of the receptor by the synthetic agonist GSK 4112. Target: Others. Smiles: CCOC(=O)C1Cc2ccccc2CN1C(=O)c1ccc(SC)s1. References: Kojetin D , Wang Y , Kamenecka T M , et al. Identification of SR8278, a Synthetic Antagonist of the...
| Anwendung: | NR1D1 antagonist |
| CAS | 1254944-66-5 |
| MW: | 361.48 D |
ab 40,00 €
Anti-Recombinant NR1D1, clone R05-8B1
Artikelnummer: E-AB-81587.100
This gene encodes a transcription factor that is a member of the nuclear receptor subfamily 1. The encoded protein is a ligand-sensitive transcription factor that negatively regulates the expression of core clock proteins. In particular this protein represses the circadian clock transcription factor aryl hydrocarbon...
| Schlagworte: | Anti-EAR1, Anti-EAR-1, Anti-NR1D1, Anti-Rev-erbA-alpha, Anti-V-erbA-related protein 1, Anti-Nuclear receptor subfamily 1... |
| Anwendung: | WB, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 195,00 €
Anti-NR1D1, recombinant antibody
Artikelnummer: ABS-RC-15815.100
Protein function: Transcriptional repressor which coordinates circadian rhythm and metabolic pathways in a heme-dependent manner. Integral component of the complex transcription machinery that governs circadian rhythmicity and forms a critical negative limb of the circadian clock by directly repressing the...
| Schlagworte: | Anti-EAR1, Anti-EAR-1, Anti-NR1D1, Anti-Rev-erbA-alpha, Anti-V-erbA-related protein 1, Anti-Nuclear receptor subfamily 1... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 206,00 €