Zu "K03574" wurden 34 Artikel gefunden!
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Anti-NUDT15 / Nudix hydrolase 15
Artikelnummer: NSJ-RQ8724
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Nudix hydrolase 15 is a protein that in humans is encoded by the NUDT15 gene. This gene encodes an enzyme that belongs to the Nudix hydrolase superfamily. Members of this superfamily catalyze the hydrolysis of nucleoside diphosphates, including substrates like...
| Schlagworte: | Anti-NUDT15, Anti-MutT homolog 2, Anti-Nucleotide triphosphate diphosphatase NUDT15, Anti-Nucleoside diphosphate-linked... |
| Anwendung: | WB, IF, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
790,00 €
Anti-NUDT15
Artikelnummer: ATA-HPA038969.100
Protein function: May catalyze the hydrolysis of nucleoside triphosphates including dGTP, dTTP, dCTP, their oxidized forms like 8-oxo-dGTP and the prodrug thiopurine derivatives 6-thio-dGTP and 6-thio-GTP (PubMed:26238318). Could also catalyze the hydrolysis of some nucleoside diphosphate derivatives...
| Schlagworte: | Anti-MTH2, Anti-MutT homolog 2, Anti-Nudix motif 15, Anti-Nudix hydrolase 15, Anti-Nucleotide triphosphate diphosphatase... |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 369,00 €
TH-1760
Artikelnummer: Cay40469-10
TH-1760 is an inhibitor of nucleotide triphosphate diphosphatase NUDT15 (IC50 = 25 nM). It is selective for NUDT15 over a panel of additional Nudix family hydrolases and nucleotide pyrophosphatases at 100 µM, as well as a panel of 44 kinases at 10 µM. TH-1760 enhances thiopurine-induced cell death in NB4 and HL-60...
| Schlagworte: | 6-[[4-(1H-indol-5-ylcarbonyl)-1-piperazinyl]sulfonyl]-2(3H)-benzoxazolone |
| Anwendung: | NUDT15 inhibitor |
| CAS | 2567914-01-4 |
| MW: | 426.4 D |
ab 88,00 €
8-oxo-dGTP diphosphatase (mutT), Escherichia coli,...
Artikelnummer: CSB-EP357355ENV.1
Organism: Escherichia coli (strain K12). Source: E.coli. Expression Region: 1-129aa. Protein Length: Full Length. Tag Info: N-terminal 6xHis-SUMO-tagged. Target Protein Sequence: MKKLQIAVGI IRNENNEIFI TRRAADAHMA NKLEFPGGKI EMGETPEQAV VRELQEEVGI TPQHFSLFEK LEYEFPDRHI TLWFWLVERW EGEPWGKEGQ PGEWMSLVGL NADDFPPANE...
| Schlagworte: | mutT, b0099, EC=3.6.1.55, 8-oxo-dGTPase, Mutator protein MutT, 8-oxo-dGTP diphosphatase, dGTP pyrophosphohydrolase,... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | E.coli |
| MW: | 30.9 kD |
ab 364,00 €
8-oxo-dGTP diphosphatase (mutT), Escherichia coli,...
Artikelnummer: CSB-YP357355ENV.1
Organism: Escherichia coli (strain K12). Source: Yeast. Expression Region: 1-129aa. Protein Length: Full Length. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: MKKLQIAVGI IRNENNEIFI TRRAADAHMA NKLEFPGGKI EMGETPEQAV VRELQEEVGI TPQHFSLFEK LEYEFPDRHI TLWFWLVERW EGEPWGKEGQ PGEWMSLVGL NADDFPPANE PVIAKLKRL....
| Schlagworte: | mutT, b0099, EC=3.6.1.55, 8-oxo-dGTPase, Mutator protein MutT, 8-oxo-dGTP diphosphatase, dGTP pyrophosphohydrolase,... |
| Anwendung: | Activity not tested |
| Exprimiert in: | Yeast |
| Ursprungsart: | E.coli |
| MW: | 16.9 kD |
ab 407,00 €
8-oxo-dGTP diphosphatase Protein, E. coli, Recombinant...
Artikelnummer: TGM-TMPH-00568-100ug
Description: 8-oxo-dGTP diphosphatase Protein, E. coli, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 30.9 kDa and the accession number is P08337.
| Schlagworte: | 8-oxo-dGTP diphosphatase, dGTP pyrophosphohydrolase, Mutator protein MutT, mutT, 8-oxo-dGTPase,... |
| MW: | 30.9 kD |
ab 340,00 €
TH1760
Artikelnummer: TGM-T67864-100mg
Description: TH1760 (MKB) is an inhibitor of NUDIX-type 15 (NUDT15, IC50= 25 nM). TH1760 can sensitize cells to 6-thioguanine by increasing the accumulation of 6-thio- (d) GTP in nucleic acids. TH1760 can enhance the anti-leukemia effect of thiopurine. Target: NUDIX hydrolase. Smiles:...
| Schlagworte: | MKB |
| Anwendung: | NUDT15 inhibitor |
| CAS | 2567914-01-4 |
| MW: | 426.45 D |
ab 48,00 €
NEU
8-oxo-dGTP diphosphatase Protein, E. coli, Recombinant...
Artikelnummer: TGM-TMPH-00568-10ug
Description: 8-oxo-dGTP diphosphatase Protein, E. coli, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 30.9 kDa and the accession number is P08337.
| Schlagworte: | Mutator protein MutT , dGTP pyrophosphohydrolase , mutT , 8-oxo-dGTPase , 7,8-dihydro-8-oxoguanine-triphosphatase ,... |
| MW: | 30.9 kD |
ab 122,00 €
NUDT15 (human), recombinant protein
Artikelnummer: ABS-PP-5482-L.100
Protein function: May catalyze the hydrolysis of nucleoside triphosphates including dGTP, dTTP, dCTP, their oxidized forms like 8-oxo-dGTP and the prodrug thiopurine derivatives 6-thio-dGTP and 6-thio-GTP (PubMed:26238318). Could also catalyze the hydrolysis of some nucleoside diphosphate derivatives...
| Schlagworte: | Nucleotide triphosphate diphosphatase NUDT15, MutT homolog 2, MTH2, Nucleoside diphosphate-linked moiety X motif 15, Nudix... |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 19.5 kD |
ab 115,00 €
Anti-NUDT1
Artikelnummer: CSB-PA874934XA01DOA.100
Make to order. Production time: 70-80 business days. Deliverables: 1. 200 µg antigen (used as positive control), 2. 1 ml pre-immune serum (used as negative control) , 3. Rabbit polyclonal antibody, antigen affinity purified. Quality Guarantee: 1. Antibody purity > 90% confirmed by SDS-PAGE, 2. Antibody titer > 1:...
| Schlagworte: | Anti-NUDX1, Anti-NUDT1, Anti-AtNUDT1, Anti-At1g68760, Anti-F14K14.13, EC=3.6.1.55, EC=3.6.1.22, Anti-8-oxo-dGTPase,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | Arabidopsis thaliana (Mouse-ear cress) |
ab 1.529,00 €
NUDT1, Human nudix (nucleoside diphosphate linked moiety...
Artikelnummer: VHPS-6373
Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
| Schlagworte: | NUDT1, hCG_18431, NUDT1 protein, Nudix (Nucleoside diphosphate linked moiety X)-type motif 1, Nudix (Nucleoside... |
| Anwendung: | RNA quantification |
45,00 €
Nudt1, Mouse nudix (nucleoside diphosphate linked moiety...
Artikelnummer: VMPS-4376
Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
| Schlagworte: | Mth1, Nudt1, EC=3.6.1.-, Nudix motif 1, 8-oxo-dGTPase, 7,8-dihydro-8-oxoguanine triphosphatase, Nucleoside... |
| Anwendung: | RNA quantification |
45,00 €