Zu "K03099" wurden 54 Artikel gefunden!
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Anti-SOS1 / Son of sevenless 1
Artikelnummer: NSJ-FY12583
Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml. SOS1 antibody detects Son of sevenless homolog 1, a guanine nucleotide exchange factor (GEF) that activates Ras and Rac GTPases, serving as a critical link between receptor tyrosine kinases and downstream signaling cascades. SOS1 catalyzes the...
| Schlagworte: | Anti-SOS1, Anti-Son of sevenless homolog 1, SOS1 Antibody / Son of sevenless 1 |
| Anwendung: | WB, IHC, FC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
Anti-SOS1
Artikelnummer: ATA-HPA076088.100
Rabbit Polyclonal SOS1 Antibody against Human SOS Ras/Rac guanine nucleotide exchange factor 1. Validated for Western Blot. Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Interspecies information: Highest antigen sequence indentity to the following orthologs: ENSMUSG00000024241:...
| Schlagworte: | Anti-SOS1, Anti-SOS-1, Anti-Son of sevenless homolog 1 |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 330,00 €
Anti-SOS1
Artikelnummer: A301-890A
Protein function: Promotes the exchange of Ras-bound GDP by GTP (PubMed:8493579). Probably by promoting Ras activation, regulates phosphorylation of MAP kinase MAPK3 in response to EGF (PubMed:17339331). Catalytic component of a trimeric complex that participates in transduction of signals from Ras to Rac by...
| Schlagworte: | Anti-SOS1, Anti-SOS-1, Anti-Son of sevenless homolog 1 |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
Ras Inhibitory Peptide
Artikelnummer: Cay17474-1
Son of sevenless homolog 1 (Sos1) is a guanine nucleotide exchange factor (GEF) that directs the exchange of Ras-GDP to Ras-GTP by binding to SH3 domains of the growth factor receptor-bound protein 2 (Grb2), leading to the activation of ERK. Ras inhibitory peptide is a synthetic peptide that contains the sequence...
| Schlagworte: | Sos SH3 Domain Inhibitor |
| Anwendung: | SOS1-Grb3 interaction inhibitor |
| CAS | 159088-48-9 |
| MW: | 1170.4 D |
ab 102,00 €
Anti-SOS1
Artikelnummer: A301-889A
Protein function: Promotes the exchange of Ras-bound GDP by GTP (PubMed:8493579). Probably by promoting Ras activation, regulates phosphorylation of MAP kinase MAPK3 in response to EGF (PubMed:17339331). Catalytic component of a trimeric complex that participates in transduction of signals from Ras to Rac by...
| Schlagworte: | Anti-SOS1, Anti-SOS-1, Anti-Son of sevenless homolog 1 |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
Anti-SOS2
Artikelnummer: A301-893A
Protein function: Promotes the exchange of Ras-bound GDP by GTP. [The UniProt Consortium]
| Schlagworte: | Anti-SOS2, Anti-SOS-2, Anti-Son of sevenless homolog 2 |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 165,00 €
SOS1, FLAG-Tag Recombinant
Artikelnummer: BPS-101573
Recombinant human SOS1 (son of sevenless homolog 1), encompassing amino acids 564-1049. This construct contains a C-terminus Flag-tag. This recombinant protein was affinity purified.
| Schlagworte: | SOS1, SOS-1, Son of sevenless homolog 1, SOS1 (564-1049-FLAG) |
| Anwendung: | Ras signaling studies |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 58 kD |
506,00 €
MRTX-0902
Artikelnummer: Cay38578-1
MRTX-0902 is an inhibitor of the protein-protein interaction between son of sevenless homolog 1 (SOS1) and K-Ras containing a glycine-to-cysteine mutation at position 12 (K-RasG12C, Ki = 1.9 nM). It is selective for the SOS1-K-RasG12C protein-protein interaction over the SOS1 and wild-type K-Ras protein-protein...
| Schlagworte: | 2-methyl-3-[(1R)-1-[[4-methyl-7-(4-morpholinyl)pyrido[3,4-d]pyridazin-1-yl]amino]ethyl]-benzonitrile |
| Anwendung: | SOS1-K-Ras(G12C) protein-protein interaction inhibitor |
| CAS | 2654743-22-1 |
| MW: | 388.5 D |
ab 112,00 €
Anti-Sos, clone SOS-01
Artikelnummer: ARG63100.100
Protein function: Promotes the exchange of Ras-bound GDP by GTP. [The UniProt Consortium]
| Schlagworte: | Anti-SOS2, Anti-SOS-2, Anti-Son of sevenless homolog 2 |
| Anwendung: | ICC, IF, WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, mouse |
658,00 €
Anti-SOS1
Artikelnummer: ARG41821.100
Protein function: Promotes the exchange of Ras-bound GDP by GTP (PubMed:8493579). Probably by promoting Ras activation, regulates phosphorylation of MAP kinase MAPK3 in response to EGF (PubMed:17339331). Catalytic component of a trimeric complex that participates in transduction of signals from Ras to Rac by...
| Schlagworte: | Anti-SOS1, Anti-SOS-1, Anti-Son of sevenless homolog 1 |
| Anwendung: | ICC, IF, IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
658,00 €
Anti-SOS2
Artikelnummer: ARG66696.100
Protein function: Promotes the exchange of Ras-bound GDP by GTP. [The UniProt Consortium]
| Schlagworte: | Anti-SOS2, Anti-SOS-2, Anti-Son of sevenless homolog 2 |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
658,00 €
SOS1, FLAG-Tag, Avi-Tag, Biotin-Labeled
Artikelnummer: BPS-100753-1
Human Son of sevenless homolog 1 (SOS1), also known as guanine nucleotide exchange factor 1 (GF1), GenBank Accession No. NM_005633, a.a. 594-1049, with N-terminal FLAG-tag and C-terminal Avi-tag, expressed in a Baculovirus infected Sf9 cell expression system, MW=57 kDa. This protein is enzymatically biotinylated...
| Schlagworte: | SOS1, SOS-1, Son of sevenless homolog 1, |
| Anwendung: | Ras signaling studies |
| Exprimiert in: | insect cells |
| Ursprungsart: | human |
| MW: | 57 kD |
ab 468,00 €