Zu "K03099" wurden 35 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
MRTX-0902
Artikelnummer: Cay38578-1
MRTX-0902 is an inhibitor of the protein-protein interaction between son of sevenless homolog 1 (SOS1) and K-Ras containing a glycine-to-cysteine mutation at position 12 (K-RasG12C, Ki = 1.9 nM). It is selective for the SOS1-K-RasG12C protein-protein interaction over the SOS1 and wild-type K-Ras protein-protein...
| Schlagworte: | 2-methyl-3-[(1R)-1-[[4-methyl-7-(4-morpholinyl)pyrido[3,4-d]pyridazin-1-yl]amino]ethyl]-benzonitrile |
| Anwendung: | SOS1-K-Ras(G12C) protein-protein interaction inhibitor |
| CAS | 2654743-22-1 |
| MW: | 388.5 D |
ab 101,00 €
Anti-SOS1
Artikelnummer: A301-890A
Protein function: Promotes the exchange of Ras-bound GDP by GTP (PubMed:8493579). Probably by promoting Ras activation, regulates phosphorylation of MAP kinase MAPK3 in response to EGF (PubMed:17339331). Catalytic component of a trimeric complex that participates in transduction of signals from Ras to Rac by...
| Schlagworte: | Anti-SOS1, Anti-SOS-1, Anti-Son of sevenless homolog 1 |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 164,00 €
Ras Inhibitory Peptide
Artikelnummer: Cay17474-1
Son of sevenless homolog 1 (Sos1) is a guanine nucleotide exchange factor (GEF) that directs the exchange of Ras-GDP to Ras-GTP by binding to SH3 domains of the growth factor receptor-bound protein 2 (Grb2), leading to the activation of ERK. Ras inhibitory peptide is a synthetic peptide that contains the sequence...
| Schlagworte: | Sos SH3 Domain Inhibitor |
| Anwendung: | SOS1-Grb3 interaction inhibitor |
| CAS | 159088-48-9 |
| MW: | 1170.4 D |
ab 92,00 €
Anti-SOS1
Artikelnummer: A301-889A
Protein function: Promotes the exchange of Ras-bound GDP by GTP (PubMed:8493579). Probably by promoting Ras activation, regulates phosphorylation of MAP kinase MAPK3 in response to EGF (PubMed:17339331). Catalytic component of a trimeric complex that participates in transduction of signals from Ras to Rac by...
| Schlagworte: | Anti-SOS1, Anti-SOS-1, Anti-Son of sevenless homolog 1 |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 164,00 €
Anti-SOS2
Artikelnummer: A301-893A
Protein function: Promotes the exchange of Ras-bound GDP by GTP. [The UniProt Consortium]
| Schlagworte: | Anti-SOS2, Anti-SOS-2, Anti-Son of sevenless homolog 2 |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 164,00 €
SOS1, FLAG-Tag Recombinant
Artikelnummer: BPS-101573
Recombinant human SOS1 (son of sevenless homolog 1), encompassing amino acids 564-1049. This construct contains a C-terminus Flag-tag. This recombinant protein was affinity purified.
| Schlagworte: | SOS1, SOS-1, Son of sevenless homolog 1, SOS1 (564-1049-FLAG) |
| Anwendung: | Ras signaling studies |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 58 kD |
496,00 €
Anti-Sos, clone SOS-01
Artikelnummer: ARG63100.100
Protein function: Promotes the exchange of Ras-bound GDP by GTP. [The UniProt Consortium]
| Schlagworte: | Anti-SOS2, Anti-SOS-2, Anti-Son of sevenless homolog 2 |
| Anwendung: | ICC, IF, WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, mouse |
624,00 €
Anti-SOS1
Artikelnummer: E-AB-62223.120
This gene encodes a protein that is a guanine nucleotide exchange factor for RAS proteins, membrane proteins that bind guanine nucleotides and participate in signal transduction pathways. GTP binding activates and GTP hydrolysis inactivates RAS proteins. The product of this gene may regulate RAS proteins by...
| Schlagworte: | Anti-SOS1, Anti-SOS-1, Anti-Son of sevenless homolog 1, SOS1 Polyclonal Antibody |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 198,00 €
Anti-SOS1
Artikelnummer: ARG41821.100
Protein function: Promotes the exchange of Ras-bound GDP by GTP (PubMed:8493579). Probably by promoting Ras activation, regulates phosphorylation of MAP kinase MAPK3 in response to EGF (PubMed:17339331). Catalytic component of a trimeric complex that participates in transduction of signals from Ras to Rac by...
| Schlagworte: | Anti-SOS1, Anti-SOS-1, Anti-Son of sevenless homolog 1 |
| Anwendung: | ICC, IF, IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
624,00 €
Anti-Sos Monoclonal Antibody (Clone:SOS-01)
Artikelnummer: ABE-30-1360-0.1
The guanine nucleotide exchange factor Sos (Son-of-sevenless) is a complex multidomain protein that activates the small GTPase Ras (H-Ras, K-Ras, N-Ras, but not functionally distinct R-Ras) in response to receptor tyrosine kinase stimulation. Nucleotide exchange activity of Sos is stimulated by allosteric Ras...
| Schlagworte: | Anti-SOS1, Anti-SOS-1, Anti-Son of sevenless homolog 1, Anti-Sos Monoclonal Antibody (Clone:SOS-01) |
| Anwendung: | WB, ICC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, mouse |
608,00 €
Anti-SOS2
Artikelnummer: ARG66696.100
Protein function: Promotes the exchange of Ras-bound GDP by GTP. [The UniProt Consortium]
| Schlagworte: | Anti-SOS2, Anti-SOS-2, Anti-Son of sevenless homolog 2 |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
624,00 €
SOS1, FLAG-Tag, Avi-Tag, Biotin-Labeled
Artikelnummer: BPS-100753-1
Human Son of sevenless homolog 1 (SOS1), also known as guanine nucleotide exchange factor 1 (GF1), GenBank Accession No. NM_005633, a.a. 594-1049, with N-terminal FLAG-tag and C-terminal Avi-tag, expressed in a Baculovirus infected Sf9 cell expression system, MW=57 kDa. This protein is enzymatically biotinylated...
| Schlagworte: | SOS1, SOS-1, Son of sevenless homolog 1, |
| Anwendung: | Ras signaling studies |
| Exprimiert in: | insect cells |
| Ursprungsart: | human |
| MW: | 57 kD |
ab 459,00 €