Zu "K03097" wurden 136 Artikel gefunden!
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Anti-Recombinant CSNK2A1, clone A462
Artikelnummer: E-AN301754L.100
Casein kinase II subunit alpha (CSNK2A1) is a catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. CSNK2A1 regulates numerous cellular processes, such as...
| Schlagworte: | Anti-CSNK2A1, Anti-Casein kinase II subunit alpha, Recombinant CSNK2A1 Monoclonal Antibody |
| Anwendung: | WB, IHC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat |
ab 304,00 €
GO289
Artikelnummer: Cay43959-1
GO289 is an inhibitor of casein kinase 2 (CK2, IC50 = 7 nM). It is selective for CK2 over a panel of 59 other kinases at 5 µM. GO289 (8 or 24 µM) increases the circadian period in a reporter assay using U2OS cells. It decreases levels of phosphorylated Akt and cell division cycle 37 (Cdc37) in C2C12 skeletal muscle...
| Schlagworte: | 5-bromo-2-methoxy-4-[[[3-(methylthio)-5-phenyl-4H-1,2,4-triazol-4-yl]imino]methyl]-phenol |
| Anwendung: | CK2 inhibitor |
| CAS | 694522-87-7 |
| MW: | 419.3 D |
ab 38,00 €
Anti-CSNK2A1
Artikelnummer: ATA-HPA069734.100
Rabbit Polyclonal CSNK2A1 Antibody against Human casein kinase 2 alpha 1. Validated for Western Blot. Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Interspecies information: Highest antigen sequence indentity to the following orthologs: ENSMUSG00000074698: 94%,...
| Schlagworte: | Anti-CK2A1, Anti-CSNK2A1, Anti-CK II alpha, Anti-Casein kinase II subunit alpha |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 330,00 €
Apigenin
Artikelnummer: Cay10010275-25
Apigenin is a flavonoid compound found in many fruits and vegetables that selectively inhibits casein kinase 2 (CK2). Apigenin inhibits CK2 activity in the renal cortex with an IC50 value of 30 µM to improve renal function in a rat model of glomerulonephritis. CK2 inhibition by 20 µM apigenin decreases the...
| Schlagworte: | Chamomile, Flavone, NSC 83244, Versulin, 5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one |
| Anwendung: | CK2 inhibitor |
| CAS | 520-36-5 |
| MW: | 270.2 D |
ab 95,00 €
CX-4945
Artikelnummer: Cay16779-10
CX-4945 is a potent, orally bioavailable inhibitor of casein kinase 2 (CK2, Ki = 0.38 nM) that competes with ATP by filling the small ATP binding site on the catalytic CK2alpha subunit, conferring selectivity. It inhibits proliferation in a panel of cancer cell lines that overexpress CK2 and prevents tumor growth of...
| Schlagworte: | Silmitasertib, 5-[(3-chlorophenyl)amino]-benzo[c]-2,6-naphthyridine-8-carboxylic acid |
| Anwendung: | CK2 inhibitor |
| CAS | 1009820-21-6 |
| MW: | 349.8 D |
ab 93,00 €
TBCA
Artikelnummer: Cay14831-1
Casein kinase 2 (CK2) is a kinase with many targets and diverse roles in cell signaling and disease. TBCA is a selective, cell-permeable inhibitor of CK2 (IC50 = 0.11 µM, Ki = 77 nM) that has minimal effect on a panel of 28 other kinases. It induces cell death in Jurkat adult T cell leukemia cells (DC50 = 7.7 µM),...
| Schlagworte: | Casein Kinase II Inhibitor III, Tetrabromocinnamic Acid, (2E)-3-(2,3,4,5-tetrabromophenyl)-2-propenoic acid |
| Anwendung: | Selective, cell-permeable Casein kinase 2 (CK2) inhibitor |
| CAS | 934358-00-6 |
| MW: | 463.7 D |
ab 56,00 €
Emodin
Artikelnummer: Cay13109-25
Emodin is a naturally-occurring anthraquinone found in a variety of plants used in traditional Chinese medicine. Purified emodin has diverse effects, including the suppression of inflammation, dyslipidemia, and cancer. At a molecular level, emodin directly and selectively inhibits casein kinase II (IC50 = 0.89 µM)....
| Schlagworte: | Archin, Frangulic Acid, NSC 408120, NSC 622947, Schuttgelb, 1,3,8-trihydroxy-6-methyl-9,10-anthracenedione |
| Anwendung: | CK2 inhibitor |
| CAS | 518-82-1 |
| MW: | 270.2 D |
ab 45,00 €
DMAT
Artikelnummer: Cay21182-1
DMAT is a cell-permeable inhibitor of casein kinase 2 (CK2, IC50 = 0.13 µM). It also inhibits Pim-1, Pim-3, HIPK2, and HIPK3 (IC50s = 0.15, 0.097, 0.37, and 0.59 µM, respectively). DMAT blocks cell growth and induces cell death in cancer cells, both in culture and in mouse xenografts.Formal Name:...
| Schlagworte: | 2-Dimethylamino-4,5,6,7-tetrabromobenzimidazole, Casein Kinase II Inhibitor II,... |
| Anwendung: | CK2 inhibitor |
| CAS | 749234-11-5 |
| MW: | 476.8 D |
ab 56,00 €
Apigenin-d5
Artikelnummer: Cay22106-1
Apigenin-d5 is an internal standard for the quantificaiton of apigenin (Cay-10010275) by GC- or LC-MS. Apigenin is a flavonoid compound found in many fruits and vegetables that selectively inhibits casein kinase 2 (CK2). Apigenin inhibits CK2 activity in the renal cortex with an IC50 value of 30 µM to improve renal...
| Schlagworte: | [3,6,8,3',5'-d5]-Apigenin, Chamomile-d5, Flavone-d5, Versulin-d5,... |
| Anwendung: | GC-MS, LC-MS, internal standard, CK2 inhibitor |
| CAS | 263711-74-6 |
| MW: | 275.3 D |
ab 216,00 €
TTP 22
Artikelnummer: Cay17702-1
TTP 22 is a thienopyrimidine compound that inhibits casein kinase 2 (CK2) with an IC50 value of 100 nM (Ki = 40 nM). It displays selectivity for CK2 over JNK3, ROCK1, and MET with no inhibitory effects towards these kinases at 10 µM.Formal Name: 3-[[5-(4-methylphenyl)thieno[2,3-d]pyrimidin-4-yl]thio]-propanoic acid....
| Schlagworte: | 3-[[5-(4-methylphenyl)thieno[2,3-d]pyrimidin-4-yl]thio]-propanoic acid |
| Anwendung: | Casein kinase 2 (CK2) inhibitor |
| CAS | 329907-28-0 |
| MW: | 330.4 D |
ab 49,00 €
Anti-CKII alpha
Artikelnummer: A300-196A-T
Protein function: Catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Regulates numerous cellular processes, such as cell cycle progression, apoptosis and...
| Schlagworte: | Anti-CK2A1, Anti-CSNK2A1, Anti-CK II alpha, EC=2.7.11.1, Anti-Casein kinase II subunit alpha |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
Anti-CKII alpha
Artikelnummer: A300-198A
Protein function: Catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Regulates numerous cellular processes, such as cell cycle progression, apoptosis and...
| Schlagworte: | Anti-CK2A1, Anti-CSNK2A1, Anti-CK II alpha, EC=2.7.11.1, Anti-Casein kinase II subunit alpha |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 165,00 €