Zu "K03083" wurden 156 Artikel gefunden!
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CHIR99021
Artikelnummer: Cay13122-1
CHIR99021 is an aminopyrimidine derivative that inhibits GSK3alpha and GSK3beta with IC50 values of 10 and 6.7 nM, respectively. When tested against twenty different protein kinases, this inhibitor shows greater than 500-fold selectivity for GSK3. CHIR99021 activates glycogen synthesis in CHO-IR cells (EC50 = 0.763...
| Schlagworte: | CT 99021,... |
| Anwendung: | GSK3alpha and GSK3beta inhibitor |
| CAS | 252917-06-9 |
| MW: | 465.3 D |
ab 43,00 €
WIC1
Artikelnummer: Cay39574-10
WIC1 is an inhibitor of Wnt signaling. It inhibits Wnt signaling induced by the glycogen synthase kinase 3beta (GSK3beta) inhibitor CHIR99021 (Cay-13122) in a reporter assay using BEAS-2B cells when used at a concentration of 100 nM. WIC1 (1 µM) induces differentiation of, and decreases CHIR99021-induced...
| Schlagworte: | Wnt Inhibitor Compound 1, N-[4-(4-ethyl-1-piperazinyl)phenyl]-2-oxo-2H-1-benzopyran-3-carboxamide |
| Anwendung: | Wnt signaling inhibitor |
| CAS | 943083-58-7 |
| MW: | 377.4 D |
ab 48,00 €
Mouse GSK3b (Glycogen Synthase Kinase 3 Beta) ELISA Kit
Artikelnummer: ELK-ELK0563.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse GSK3b. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse GSK3b. Next,...
| Schlagworte: | GSK-3 beta, Glycogen synthase kinase-3 beta, Serine/threonine-protein kinase GSK3B |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
ab 365,00 €
Human GSK3b (Glycogen Synthase Kinase 3 Beta) ELISA Kit
Artikelnummer: ELK-ELK3753.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human GSK3b. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human GSK3b. Next,...
| Schlagworte: | GSK-3 beta, Glycogen synthase kinase-3 beta, Serine/threonine-protein kinase GSK3B |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €
Rat GSK3b (Glycogen Synthase Kinase 3 Beta) ELISA Kit
Artikelnummer: ELK-ELK6544.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat GSK3b. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat GSK3b. Next,...
| Schlagworte: | FA, Factor A, GSK-3 beta, Glycogen synthase kinase-3 beta, Serine/threonine-protein kinase GSK3B |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | rat |
ab 365,00 €
Anti-GSK 3beta
Artikelnummer: ELK-EA169.50
Glycogen synthase kinase 3 beta, also known as GSK3B, is an enzyme that in humans is encoded by the GSK3B gene. Protein function: Constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcription factors and...
| Schlagworte: | Anti-GSK-3 beta, Anti-Glycogen synthase kinase-3 beta, Anti-Serine/threonine-protein kinase GSK3B, GSK 3beta Rabbit pAb |
| Anwendung: | WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
169,00 €
CHIR99021 (hydrochloride)
Artikelnummer: Cay39176-1
CHIR99021 is an aminopyrimidine derivative that inhibits GSK3alpha and GSK3beta with IC50 values of 10 and 6.7 nM, respectively. When tested against twenty different protein kinases, this inhibitor shows greater than 500-fold selectivity for GSK3. CHIR99021 activates glycogen synthesis in CHO-IR cells (EC50 = 0.763...
| Schlagworte: | CT 99021,... |
| Anwendung: | Aminopyrimidine derivative, GSK3alpha / GSK3beta inhibitor |
| CAS | 1797989-42-4 |
| MW: | 501.8 D |
ab 34,00 €
SB-216763
Artikelnummer: Cay10010246-5
Glycogen synthase kinase 3 (GSK3) is a serine/threonine protein kinase that is inhibited by an assortment of extracellular stimuli including insulin, growth factors, cell specification factors, and cell adhesion. SB-216763 is a potent and selective cell permeable ATP-competitive inhibitor of GSK3alpha with an IC50...
| Schlagworte: | 3-(2,4-dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione |
| Anwendung: | GSK inhibitor |
| CAS | 280744-09-4 |
| MW: | 371.2 D |
ab 98,00 €
Anti-phospho-GSK3 beta (Ser9)
Artikelnummer: ARG43825.100
Protein function: Constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcription factors and microtubules, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), EIF2B, CTNNB1/beta-catenin, APC,...
| Schlagworte: | Anti-phospho-GSK3B, Anti-phospho-GSK-3 beta, Anti-phospho-GSK-3 beta, Anti-phospho-Glycogen synthase kinase-3 beta,... |
| Anwendung: | ICC, IF, IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
624,00 €
GSK3beta, active human recombinant protein
Artikelnummer: BPS-40007
Active human GSK3beta GenBank Accession No. NM_002093), full length, with N-terminal GST tag, MW=73 kDa, expressed in a Baculovirus infected Sf9 cell expression system.
| Schlagworte: | GSK-3 beta, Glycogen synthase kinase-3 beta, Serine/threonine-protein kinase GSK3B, |
| Anwendung: | Enzyme kinetics, inhibitor screening |
| MW: | 73 kD |
540,00 €
Manzamine A
Artikelnummer: Cay21444-1
Manzamine A is a beta-carboline alkaloid with diverse activities that has been found in marine sponges, including X. ashmorica. It is an inhibitor of glycogen synthase kinase 3beta (GSK3beta) and cyclin-dependent kinase 5 (CDK5, IC50s = 10.2 and 1.5 µM, respectively). It inhibits the growth of L5178y mouse lymphoma...
| Schlagworte: | Keramamine A,... |
| Anwendung: | Antiinflammatory GSK-3beta inhibitor |
| CAS | 104196-68-1 |
| MW: | 548.8 D |
ab 164,00 €
BIO
Artikelnummer: Cay13123-1
BIO is a cell-permeable bis-indolo (indirubin) compound that acts as a highly potent, selective, reversible, and ATP-competitive inhibitor of GSK3alpha/beta (IC50 = 5 nM). Its specificity has been tested against various cyclin-dependent kinases (CDKs) (IC50s = 83, 300, 320, and 10,000 nM for Cdk5/p25, Cdk2/A,...
| Schlagworte: | GSK3 Inhibitor IX, 6-Bromoindirubin-3'-oxime, MLS 2052,... |
| Anwendung: | GSK-3 inhibitor |
| CAS | 667463-62-9 |
| MW: | 356.2 D |
ab 43,00 €