Zu "K02833" wurden 58 Artikel gefunden!
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Erastin
Artikelnummer: Cay17754-1
Erastin, named for eradicator of RAS and small T (ST) antigen-expressing cells, is a ferroptosis inducer. It induces ferroptotic cell death in vitro, an effect that can be blocked by the ferroptosis inhibitors ciclopirox olamine, Trolox (Cay-10011659), ferrostatin-1 (Cay-17729), U-0126 (Cay-70970), cycloheximide...
| Schlagworte: | 2-[1-[4-[2-(4-chlorophenoxy)acetyl]-1-piperazinyl]ethyl]-3-(2-ethoxyphenyl)-4(3H)-quinazolinone |
| Anwendung: | Antitumor agent |
| CAS | 571203-78-6 |
| MW: | 547.1 D |
ab 60,00 €
ML-210
Artikelnummer: Cay23282-1
ML-210 is an inhibitor of glutathione peroxidase 4 (GPX4). It reduces viability of mesenchymal-state KP4 cells, an effect that can be blocked by the arachidonic acid lipoxygenase inhibitors PD 146176 (Cay-10010518) and zileuton (Cay-10006967). It is also selectively lethal to mutant RAS oncogene-expressing cells...
| Schlagworte: | DPI10, [4-[bis(4-chlorophenyl)methyl]-1-piperazinyl](5-methyl-4-nitro-3-isoxazolyl)-methanone |
| Anwendung: | HRas(G12V)-expressing cell specific cytotoxin |
| CAS | 1360705-96-9 |
| MW: | 475.3 D |
ab 43,00 €
Anti-Ras (Q61L), monoclonal
Artikelnummer: NB-26193
Recognizes Ras (Q61L), but not wild type Ras protein from vertebrates. Concentration: 1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Ras protein is a membrane associated GTPase signaling protein that regulates proliferation, differentiation, and cell survival. Ras Q61L mutation...
| Schlagworte: | Anti-HRAS, Anti-HRAS1, Anti-KRAS, Anti-KRAS2, Anti-NRAS, Anti-HRAS1, Anti-GTPase NRas, Anti-Transforming protein N-Ras... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
717,00 €
Anti-Ras (Q61R), monoclonal
Artikelnummer: NB-26192
Recognizes Ras (Q61R), but not wild type Ras protein from vertebrates. Concentration: 1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Ras protein is a membrane associated GTPase signaling protein that regulates proliferation, differentiation, and cell survival. Ras Q61R mutation...
| Schlagworte: | Anti-HRAS, Anti-HRAS1, Anti-KRAS, Anti-KRAS2, Anti-NRAS, Anti-HRAS1, Anti-GTPase NRas, Anti-Transforming protein N-Ras... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
717,00 €
Anti-H-RAS
Artikelnummer: NSJ-F41616-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. This gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic...
| Schlagworte: | Anti-HRAS, Anti-HRAS1, H-RAS Antibody |
| Anwendung: | WB, IF, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 326,00 €
Kobe 0065
Artikelnummer: Cay16261-5
The Ras family of small GTPases (H-Ras, K-Ras, and N-Ras) function as molecular switches, cycling between a GTP-bound active state and a GDP-bound inactive state, to turn on downstream Raf protein kinases. This initiates complex signaling pathways involved in cell growth, differentiation, and apoptosis. Mutations...
| Schlagworte: | N-(3-chloro-4-methylphenyl)-2-[2,6-dinitro-4-(trifluoromethyl)phenyl]-hydrazinecarbothioamide |
| Anwendung: | Ras inhibitor |
| CAS | 436133-68-5 |
| MW: | 449.8 D |
ab 50,00 €
Farnesyl Thiosalicylic Acid Amide
Artikelnummer: Cay13175-1
Association of Ras protein with the inner surface of the plasma membrane is required for Ras signaling activity. Farnesyl thiosalicylic acid (FTS) amide is an FTS derivative with an amide added to the carboxyl group. FTS amide inhibits the growth of PANC-1 and U87 tumor cells with IC50 values of 20 and 10 µM,...
| Schlagworte: | FTS Amide, Salirasib Amide, 2-[[(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrien-1-yl]thio]-benzamide |
| Anwendung: | Ras signaling inhibitor |
| CAS | 1092521-74-8 |
| MW: | 357.6 D |
ab 26,00 €
Kobe 2602
Artikelnummer: Cay16262-10
The Ras family of small GTPases (H-Ras, K-Ras, and N-Ras) function as molecular switches, cycling between a GTP-bound active state and a GDP-bound inactive state, to turn on downstream Raf protein kinases. This initiates complex signaling pathways involved in cell growth, differentiation, and apoptosis. Mutations...
| Schlagworte: | 2-[2,6-dinitro-4-(trifluoromethyl)phenyl]-N-(4-fluorophenyl)-hydrazinecarbothioamide |
| Anwendung: | RAS inhibitor |
| CAS | 454453-49-7 |
| MW: | 419.3 D |
ab 43,00 €
Anti-H-Ras, clone H-RAS-03
Artikelnummer: ARG63022.100
Protein function: Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. [The UniProt Consortium]
| Schlagworte: | Anti-HRAS, Anti-HRAS1 |
| Anwendung: | WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
624,00 €
Human H-RAS ELISA Kit
Artikelnummer: G-HUFI01189.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
641,00 €
Anti-HRAS
Artikelnummer: NSJ-R31861
0.5mg/ml if reconstituted with 0.2ml sterile DI water. GTPase HRas, also known as transforming protein p21, is an enzyme that in humans is encoded by the HRAS gene. This gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products...
| Schlagworte: | Anti-HRAS, Anti-HRAS1, HRAS Antibody |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
755,00 €
Anti-HRAS
Artikelnummer: NSJ-R31862
0.5mg/ml if reconstituted with 0.2ml sterile DI water. GTPase HRas, also known as transforming protein p21, is an enzyme that in humans is encoded by the HRAS gene. This gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products...
| Schlagworte: | Anti-HRAS, Anti-HRAS1, HRAS Antibody |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
755,00 €