Zu "K02740" wurden 31 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
ONX 0914
Artikelnummer: AG-CR1-3674-M005
Synthetic. Chemical. CAS: 960374-59-8. Formula: C31H40N4O7. MW: 580.7. Synthetic. Potent and selective 20S immunoproteasome inhibitor. Targets the beta5i subunit [LMP7] of the 20S immunoproteasome (IC50=73nM) and with minimal crossreactivity to the chymotrypsin-like beta5 subunit of the constitutive 20S proteasome...
| Schlagworte: | N-[2-(4-Morpholinyl)acetyl]-L-alanyl-O-methyl-N-[(1S)-2-[(2R)-2-methyl-2-oxiranyl]-2-oxo-1-(phenylmethyl)ethyl]-L-tyrosina... |
| Anwendung: | Potent, selective 20S immunoproteasome (PSMB8) inhibitor |
| CAS | 960374-59-8 |
| MW: | 580,7 D |
ab 61,00 €
M-3258
Artikelnummer: Cay38160-1
M-3258 is an inhibitor of the immunoproteasome subunit large multifunctional peptidase 7 (LMP7, IC50 = 4.1 nM). It is selective for LMP7 over the 20S proteasomal catalytic subunits beta1, -beta2, and -beta5 (IC50s = >10,000, 2,519, and >10,000 nM, respectively), as well as LMP2 and proteosome subunit beta type 10...
| Schlagworte: | B-[(1R)-2-(3-benzofuranyl)-1-[[(1S,2R,4R)-7-oxabicyclo[2.2.1]hept-2-ylcarbonyl]amino]ethyl]-boronic acid |
| Anwendung: | LMP7 (PSMB8, 20S immunoproteasome subunit beta 8/beta-5i) inhibitor |
| CAS | 2285330-15-4 |
| MW: | 329.2 D |
ab 135,00 €
Ac-ANW-AMC
Artikelnummer: Cay26640-1
Ac-ANW-AMC is a fluorogenic substrate for the beta5i/LMP7 subunit of the 20S immunoproteasome. Upon cleavage, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify the activity of the beta5i/LMP7 subunit of the 20S immunoproteasome. AMC displays excitation/emission maxima of...
| Schlagworte: | Ac-Ala-Asn-Trp-AMC,... |
| Anwendung: | 20S immunoproteasome beta5i/LMP7 fluorogenic substrate |
| MW: | 588.6 D |
ab 77,00 €
![Ac-Ala-Asn-Trp-AMC [Ac-ANW-AMC]](https://www.biomol.com/media/image/b8/36/48/SBB-PS0009-M002_200x200.png "Ac-Ala-Asn-Trp-AMC [Ac-ANW-AMC]")
Ac-Ala-Asn-Trp-AMC [Ac-ANW-AMC]
Artikelnummer: SBB-PS0009-M002
Lyophilized powder. Soluble in DMSO. Ac-ANW-AMC is a fluorogenic peptide substrate for measuring chymotrypsin-like activity of the immunoproteasome. Hydrolysis of this substrate by the beta5i-subunit of the immunoproteasome is monitored by observing fluorescence at an Excitation wavelength of 345nm and Emission at...
| Schlagworte: | Proteasome Substrate |
| Anwendung: | Fluorogenic peptide substrate |
| MW: | 588,6 D |
234,00 €
ONX 0914
Artikelnummer: Cay16271-1
The immunoproteasome is a specialized, inducible proteasome that generates peptides presented on major histocompatibility complex (MHC) class I molecules to cytotoxic T cells. Stimulation of cells with inflammatory cytokines such as IFN-gamma leads to the replacement of constitutive catalytic proteasome beta...
| Schlagworte: | PR-957,... |
| Anwendung: | Immunoproteasome inhibitor |
| CAS | 960374-59-8 |
| MW: | 580.7 D |
ab 84,00 €
Ac-Ala-Asn-Trp-AMC
Artikelnummer: AG-CP3-0037-M005
Ac-ANW-AMC is a fluorogenic peptide substrate for measuring chymotrypsin-like activity of the immunoproteasome. Hydrolysis of this substrate by the beta5i-subunit of the immunoproteasome is monitored by observing fluorescence at an Excitation wavelength of 345nm and Emission at 445nm. This substrate is specific to...
| Schlagworte: | Ac-ANW-AMC, acetyl-Ala-Asn-Trp-7-amido-4-methylcoumarin |
| Anwendung: | Fluorogenic immunoproteasome (PSMB9/beta1i/LMP2-subunit) substrate |
| CAS | 2357123-49-8 |
| MW: | 588.6 D |
ab 55,00 €
Anti-PSMB8 / LMP7
Artikelnummer: ARG57463.100
Protein function: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in...
| Schlagworte: | Anti-LMP7, Anti-PSMB8, EC=3.4.25.1, Anti-Macropain subunit C13, Anti-Proteasome component C13, Anti-Proteasome subunit... |
| Anwendung: | WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, rat |
624,00 €
Anti-LMP7, C-terminal
Artikelnummer: ARG64947.100
Protein function: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in...
| Schlagworte: | Anti-LMP7, Anti-PSMB8, EC=3.4.25.1, Anti-Macropain subunit C13, Anti-Proteasome component C13, Anti-Proteasome subunit... |
| Anwendung: | ELISA, WB |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
784,00 €
Anti-PSMB8/LMP7
Artikelnummer: A305-195A
Protein function: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in...
| Schlagworte: | Anti-LMP7, Anti-PSMB8, EC=3.4.25.1, Anti-Macropain subunit C13, Anti-Proteasome component C13, Anti-Proteasome subunit... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 164,00 €
Anti-PSMB8/LMP7
Artikelnummer: A305-229A
Protein function: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in...
| Schlagworte: | Anti-LMP7, Anti-PSMB8, EC=3.4.25.1, Anti-Macropain subunit C13, Anti-Proteasome component C13, Anti-Proteasome subunit... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 164,00 €
Anti-LMP7
Artikelnummer: NSJ-R33670-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Large multifunctional peptidase 7, PSMB8 Protein function: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu,...
| Schlagworte: | Anti-LMP7, Anti-PSMB8, EC=3.4.25.1, Anti-Macropain subunit C13, Anti-Proteasome component C13, Anti-Proteasome subunit... |
| Anwendung: | WB, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
755,00 €
Anti-PSMB8
Artikelnummer: E-AB-61655.120
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic...
| Schlagworte: | Anti-LMP7, Anti-PSMB8, EC=3.4.25.1, Anti-Macropain subunit C13, Anti-Proteasome component C13, Anti-Proteasome subunit... |
| Anwendung: | WB, IHC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 198,00 €