Zu "K02580" wurden 178 Artikel gefunden!
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Anti-Recombinant NF-kappaB1 p105/p50, clone 4F9
Artikelnummer: E-AN301362L.100
Nuclear factor kappa B subunit 1(NFKB1) Homo sapiens This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B...
| Schlagworte: | Anti-Nfkb1, Anti-EBP-1, Anti-DNA-binding factor KBF1, Anti-NF-kappa-B1 p84/NF-kappa-B1 p98, Anti-Nuclear factor NF-kappa-B... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
391,00 €
EN450
Artikelnummer: Cay42326-10
A molecular glue NF-kappaB degrader, reduces the viability of HAP1 leukemia cells, an effect that can be reduced by MLN4924 or bortezomib. Formulation: A solid. InChI: InChI=1S/C11H13ClN2O3S/c1-4-11(15)13-10-7-8(5-6-9(10)12)18(16,17)14(2)3/h4-7H,1H2,2-3H3,(H,13,15). InChIKey: OXFXDOLAQBMOPH-UHFFFAOYSA-N. SMILES:...
| Schlagworte: | N-[2-chloro-5-[(dimethylamino)sulfonyl]phenyl]-2-propenamide |
| Anwendung: | Molecular glue NF-kappaB degrader |
| CAS | 793719-01-4 |
| MW: | 288.7 D |
ab 112,00 €
Dimethyl diacetyl cystinate
Artikelnummer: Cay43064-100
An L-cystine derivative, inhibits UVB radiation-induced NF-kappaB nuclear translocation in and IL-1alpha secretion from HaCaT cells at 50 or 100 µM, decreases proliferation and IFN-gamma and IL-2 secretion in a co-culture of lymphocytes isolated from BALB/c mice and irradiated splenocytes isolated from C57BL/10J...
| Schlagworte: | DACDM, N,N'-Diacetyl-L-cystine Dimethylester, NSC 136019, N,N'-diacetyl-L-cystine, 1,1'-dimethyl ester |
| Anwendung: | L-cystine derivative |
| CAS | 32381-28-5 |
| MW: | 352.42 D |
ab 68,00 €
NF-kappaB (human p50) Transcription Factor Assay Kit
Artikelnummer: Cay10006912-96
Cayman's NF-kappaB (human p50) Transcription Factor Assay is a non-radioactive, sensitive method for detecting specific transcription factor DNA binding activity in nuclear extracts and whole cell lysates. A 96-well enzyme-linked immunosorbent assay (ELISA) replaces the cumbersome radioactive electrophoretic...
| Schlagworte: | EBP-1, NFKB1, DNA-binding factor KBF1, Nuclear factor NF-kappa-B p50 subunit, Nuclear factor of kappa light polypeptide... |
| Anwendung: | NF-kappaB (human p50) binding detection |
| Spezies-Reaktivität: | human |
732,00 €
NF-kappaB (p50) (human, recombinant)
Artikelnummer: Cay10009818-25
The NF-kappaB/Rel family of transcription factors is comprised of several structurally-related proteins that form homodimers and heterodimers and include p50/p105, p52/p100, RelA (p65), and c-Rel/NF-kappaB . Members of this family are responsible for regulating over 150 target genes, including the expression of...
| Schlagworte: | NFKB1, EBP-1, DNA-binding factor KBF1, Nuclear factor NF-kappa-B p50 subunit, Nuclear factor NF-kappa-B p105 subunit,... |
| Anwendung: | WB |
| MW: | 74,5 kD |
588,00 €
Andrographolide
Artikelnummer: Cay11679-50
Andrographolide is a labdane diterpenoid that is the main bioactive component of A. paniculata, a well-recognized medicinal plant in Asia. It exerts a wide range of therapeutic actions, including immunosuppressant, antithrombotic, anti-inflammatory, antineoplastic, antiviral, antibacterial, antidiabetic,...
| Schlagworte: | 3E-[2-[(1R,4aS,5R,6R,8aS)-decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethylidene]dihydr... |
| Anwendung: | Cell studies, Cancer studies |
| CAS | 5508-58-7 |
| MW: | 350.5 D |
ab 30,00 €
JSH-23
Artikelnummer: Cay15036-25
JSH-23 is an inhibitor of NF-kappaB, blocking its translocation into the nucleus (IC50 = 7.1 µM). It does not affect degradation of the inhibitor of NF-kappaB, IkappaB. JSH-23 interferes with NF-kappaB-mediated gene expression and apoptosis in RAW 264.7 cells treated with lipopolysaccharide. It has also been used to...
| Schlagworte: | NF-kappaB Activation Inhibitor II, 4-methyl-N1-(3-phenylpropyl)-1,2-benzenediamine |
| Anwendung: | NFkappaB inhibitor |
| CAS | 749886-87-1 |
| MW: | 240.3 D |
ab 73,00 €
NF-kappaB Inhibitor (trifluoroacetate salt)
Artikelnummer: Cay17493-1
NF-kappaB inhibitor is a synthetic peptide corresponding to the nuclear localization sequence of NF-kappaB p105 subunit (also known as p50) appended to a hydrophobic sequence to facilitate import into living cells. It blocks the nuclear import of p105 in cells treated with activators of NF-kappaB signaling,...
| Schlagworte: | SN50 Peptide |
| Anwendung: | NF-kappaB p105 inhibitor |
| MW: | 2781.5 D |
ab 100,00 €
Mouse Nfkb1 (Nuclear factor NF-kappa-B p105 subunit)...
Artikelnummer: G-MOFI01467.96
Range: 0.156-10ng/ml, Sensitivity: < 0.094ng/ml. Protein function: NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation,...
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
698,00 €
Anti-phospho-NFkB p105/p50 (Ser337)
Artikelnummer: ARG51521.50
Protein function: NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth,...
| Schlagworte: | Anti-phospho-NFKB1 |
| Anwendung: | ICC, IF, IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 471,00 €
Anti-phospho-NFkB p105/p50 (Ser893)
Artikelnummer: ARG51522.100
Protein function: NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth,...
| Schlagworte: | Anti-phospho-NFKB1 |
| Anwendung: | IHC, ICC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 471,00 €
Anti-phospho-NFkB p105/p50 (Ser907)
Artikelnummer: ARG51523.100
Protein function: NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth,...
| Schlagworte: | Anti-phospho-NFKB1 |
| Anwendung: | WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 460,00 €