Zu "K02470" wurden 69 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
Gepotidacin
Artikelnummer: Cay44094-1
Gepotidacin is an inhibitor of bacterial topoisomerase II. It is active against 84 bacterial clinical isolates (MICs = 0.032-8 µg/ml) and vancomycin-resistant S. aureus (VRSA) and methicillin-resistant S. aureus (MRSA, MICs = 0. and 0. µg/ml, respectively). Gepotidacin reduces the number of lung colony-forming units...
| Schlagworte: | GSK2140944 |
| Anwendung: | Bacterial topoisomerase II inhibitor |
| CAS | 1075236-89-3 |
| MW: | 448.53 D |
ab 42,00 €
Ciprofloxacin (hydrochloride hydrate)
Artikelnummer: Cay14286-5
Ciprofloxacin is a fluoroquinolone antibiotic. It is active against a variety of Gram-positive and Gram-negative bacteria in vitro, including S. aureus, L. monocytogenes, P. aeruginosa, Legionella, N. gonorrhoeae, and H. pylori (MIC50s = 0.004-1 µg/ml). It is also active against clinical isolates of Bacteroides,...
| Schlagworte: | BAY-o 9867, NSC 620634, 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid,... |
| Anwendung: | Antibiotic |
| CAS | 86393-32-0 |
| MW: | 367.8 D |
ab 56,00 €
Novobiocin (sodium salt)
Artikelnummer: Cay18457-1
Bacterial DNA gyrase is a heterodimeric type II topoisomerase that negatively supercoils circular double-stranded DNA. Novobiocin is a coumarin antibiotic, first isolated from Streptomyces species, that inhibits the ATPase activity of DNA gyrase. Its antibacterial activity arises from competitive inhibition of the...
| Schlagworte: | NSC 2382,... |
| Anwendung: | Bacterial DNA gyrase (GyrB) inhibitor |
| CAS | 1476-53-5 |
| MW: | 634.6 D |
ab 103,00 €
Levofloxacin (hydrate)
Artikelnummer: Cay20382-1
Levofloxacin is a fluoroquinolone antibiotic and the active stereoisomer of ofloxacin (Cay-22891). It is active against S. aureus, S. epidermidis, B. subtilis, E. coli, P. aeruginosa, and K. pneumoniae (MICs = 0.25, 0.25, 0.5, 0.03, 4, and 0.25 µg/ml, respectively). Levofloxacin inhibits S. aureus DNA gyrase and...
| Schlagworte: | MP-376,... |
| Anwendung: | Antibacterial, nucleic acid biosynthesis inhibitor |
| CAS | 138199-71-0 |
| MW: | 361.4 D |
ab 44,00 €
Moxifloxacin (hydrochloride)
Artikelnummer: Cay14830-100
Moxifloxacin is a fluoroquinolone antibiotic. It is active against 390 clinical isolates of aerobic and anaerobic Gram-positive and Gram-negative bacteria (MIC90s = =0.25 µg/ml), as well as clinical isolates of methicillin-susceptible and -resistant S. aureus (MIC90s = 0.12 and 2 µg/ml, respectively). Moxifloxacin...
| Schlagworte: | BAY 12-8039,... |
| Anwendung: | Antibiotic, DNA gyrase / topoisomerase IV inhibitor |
| CAS | 186826-86-8 |
| MW: | 437.9 D |
ab 139,00 €
Delafloxacin
Artikelnummer: Cay20314-5
Delafloxacin is a fluoroquinolone antibiotic that demonstrates extremely high potency against a wide range of bacteria in vitro, including levofloxacin-resistant strains of S. pneumoniae and methicillin-resistant S. aureus. It targets both DNA gyrase and topoisomerase IV. Delafloxacin has an anionic structure, which...
| Schlagworte: | ABT-492, RX-3341,... |
| Anwendung: | Antibacterial, topoisomerase IV inhibitor |
| CAS | 189279-58-1 |
| MW: | 440.8 D |
ab 73,00 €
Enrofloxacin
Artikelnummer: Cay20301-1
Enrofloxacin is a fluoroquinolone antibiotic. It is active against panels of Campylobacter, E. coli, and Salmonella isolates (mean MIC50s = 0.06, 0.5, and 0.03 µg/ml, respectively). It is also active against equine isolates of L. intracellularis (MICs = 0.125-0.5 µg/ml). Enrofloxacin inhibits bacterial DNA gyrase....
| Schlagworte: | BAY-Vp 2674, ENR, PD 160788, 1-cyclopropyl-7-(4-ethyl-1-piperazinyl)-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid |
| Anwendung: | Antibacterial antibiotic, DNA gyrase / topoisomerase IV inhibitor |
| CAS | 93106-60-6 |
| MW: | 359.4 D |
ab 49,00 €
Norfloxacin
Artikelnummer: Cay25975-5
Norfloxacin is a fluoroquinolone antibiotic that inhibits the growth of Gram-positive and Gram-negative bacteria (MICs = 4 and 1 µg/ml for S. aureus and P. aeruginosa, respectively). It also inhibits the growth S. pseudintermedius, S. aureus, E. coli, Pasturella, and S. canis isolates from dogs (mean MIC50s = 0.25,...
| Schlagworte: | 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid |
| Anwendung: | Antibacterial, topoisomerase IV inhibitor |
| CAS | 70458-96-7 |
| MW: | 319.3 D |
ab 67,00 €
Fleroxacin
Artikelnummer: Cay24173-1
Fleroxacin is a broad-spectrum fluoroquinolone antibiotic. It is active against a variety of Gram-positive and Gram-negative bacteria with MIC90 values ranging from 0.05 to 3.13 µg/ml for clinical isolates of Staphylococcus, P. aeruginosa, H. influenzae, N. gonorrhoeae, B. catarrhalis, C. jejuni, and various species...
| Schlagworte: | AM833, Ro 23-6240, 6,8-difluoro-1-(2-fluoroethyl)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid |
| Anwendung: | Antibacterial, broad-spectrum fluoroquinolone antibiotic, nucleic acid biosynthesis inhibitor |
| CAS | 79660-72-3 |
| MW: | 369.3 D |
ab 85,00 €
Pazufloxacin (mesylate)
Artikelnummer: Cay29249-1
Pazufloxacin is a broad-spectrum synthetic fluoroquinolone antibiotic. It is active against Gram-negative and Gram-positive bacteria, including clinical isolates of E. coli, K. pneumoniae, methicillin-susceptible and -resistant S. aureus, and methicillin-susceptible and -resistant S. epidermidis (MIC90s = 0.05, 0.1,...
| Schlagworte: | Pazufloxacin methanesulfonate, T-3762,... |
| Anwendung: | Broad-spectrum synthetic fluoroquinolone antibiotic, antibacter., nucleic acid biosynthesis inhibitor |
| CAS | 163680-77-1 |
| MW: | 414.4 D |
ab 56,00 €
Novo-TRX, Inhibitor
Artikelnummer: BPS-27500
Novobiocin is an aminocoumarin antibiotic that is produced by Streptomyces niveus. Along with other aminocoumarin antibiotics, novobiocin is a very potent inhibitor of bacterial DNA gyrase. It works by targeting the GyrB subunit of the enzyme involved in energy transduction. Novo-TRX is Texas Red-labeled novobiocin,...
| Schlagworte: | Texas Red-labeled novobiocin |
| Anwendung: | DNA gyrase inhibitor screening |
| CAS | 303-81-1 |
| MW: | 1357.5 D |
506,00 €
Orbifloxacin
Artikelnummer: Cay17353-50
Orbifloxacin is a fluoroquinolone antibiotic used in animals, including dogs, cattle, and swine, to combat gastrointestinal and respiratory infections. It is effective against most Gram-negative bacteria, including Enterobacteriaceae and Pseudomonas, with lower activity against Gram-positive aerobes.Formal Name:...
| Schlagworte: | CP 104,354, 1-cyclopropyl-7-[(3R,5S)-3,5-dimethyl-1-piperazinyl]-5,6,8-trifluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid |
| Anwendung: | Fluoroquinolone antibiotic, DNA gyrase inhibitor, topoisomerase IV inhibitor |
| CAS | 113617-63-3 |
| MW: | 395.4 D |
ab 67,00 €