- Suchergebnis für K02214
Cookie-Einstellungen
Diese Website benutzt Cookies, die für den technischen Betrieb der Website erforderlich sind und stets gesetzt werden. Andere Cookies, die den Komfort bei Benutzung dieser Website erhöhen, der Direktwerbung dienen oder die Interaktion mit anderen Websites und sozialen Netzwerken vereinfachen sollen, werden nur mit Ihrer Zustimmung gesetzt.
Konfiguration
Technisch erforderlich
Diese Cookies sind für die Grundfunktionen des Shops notwendig.
"Alle Cookies ablehnen" Cookie
"Alle Cookies annehmen" Cookie
Ausgewählter Shop
CSRF-Token
Cookie-Einstellungen
FACT-Finder Tracking
Individuelle Preise
Kundenspezifisches Caching
Session
Währungswechsel
Komfortfunktionen
Diese Cookies werden genutzt um das Einkaufserlebnis noch ansprechender zu gestalten, beispielsweise für die Wiedererkennung des Besuchers.
Facebook-Seite in der rechten Blog - Sidebar anzeigen
Merkzettel
Statistik & Tracking
Endgeräteerkennung
Kauf- und Surfverhalten mit Google Tag Manager
Partnerprogramm
Zu "K02214" wurden 24 Artikel gefunden!
Filter schließen
Filtern nach:
Für die Filterung wurden keine Ergebnisse gefunden!
Artikelnummer: Cay24906-25
XL413 is a potent inhibitor of Cdc7 (IC50 = 3.4 nM). It is >60, >10, and >300-fold selective for Cdc7 over CK2, PIM1, and a panel of over 100 protein kinases, respectively. XL413 inhibits the growth of MDA-MB-231T and COLO 205 cells (IC50s = 118 and 140 nM, respectively). It inhibits Cdc7-specific phosphorylation of...
Schlagworte: | 8-chloro-2-(2S)-2-pyrrolidinyl-benzofuro[3,2-d]pyrimidin-4(3H)-one, monohydrochloride |
Anwendung: | Cdc7 inhibitor |
CAS | 2062200-97-7 |
MW: | 326.2 D |
ab 40,00 €
Artikelnummer: Cay18218-10
Cdc7 kinase is a key regulator of the S-phase of the cell cycle. It is known to promote the activity of DNA replication origins in eukaryotic organisms. Inhibition of Cdc7 kinase causes blockade of DNA synthesis in human cell lines. Tumor cells are then funneled into the apoptotic pathway in a p53-independent...
Schlagworte: | CAY10572, 1,5,6,7-tetrahydro-2-(4-pyridinyl)-4H-pyrrolo[3,2-c]pyridin-4-one, monohydrochloride |
Anwendung: | Cdc7 kinase inhibitor |
CAS | 942425-68-5 |
MW: | 249.7 D |
ab 65,00 €
Artikelnummer: A302-504A
Protein function: Seems to phosphorylate critical substrates that regulate the G1/S phase transition and/or DNA replication. Can phosphorylates MCM2 and MCM3. [The UniProt Consortium]
Schlagworte: | Anti-CDC7, Anti-CDC7L1, Anti-huCdc7, Anti-HsCdc7, EC=2.7.11.1, Anti-CDC7-related kinase, Anti-Cell division cycle... |
Anwendung: | WB, IP |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 164,00 €
Artikelnummer: E-AB-16331.120
This gene encodes a cell division cycle protein with kinase activity that is critical for the G1/S transition. The yeast homolog is also essential for initiation of DNA replication as cell division occurs. Overexpression of this gene product may be associated with neoplastic transformation for some tumors. Multiple...
Schlagworte: | Anti-CDC7, Anti-CDC7L1, Anti-HsCdc7, Anti-huCdc7, EC=2.7.11.1, Anti-CDC7-related kinase, Anti-Cell division cycle... |
Anwendung: | IHC, ELISA |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse |
ab 71,00 €
Artikelnummer: E-AB-13139.120
This gene encodes a cell division cycle protein with kinase activity that is critical for the G1/S transition. The yeast homolog is also essential for initiation of DNA replication as cell division occurs. Overexpression of this gene product may be associated with neoplastic transformation for some tumors. Multiple...
Schlagworte: | Anti-CDC7, Anti-CDC7L1, Anti-HsCdc7, Anti-huCdc7, EC=2.7.11.1, Anti-CDC7-related kinase, Anti-Cell division cycle... |
Anwendung: | IHC, ELISA |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse |
ab 71,00 €
Artikelnummer: Cay25988-10
LY3177833 is an orally bioavailable inhibitor of Cdc7 kinase (IC50 = 3.3 nM for ADP production in an enzyme assay). It inhibits phosphorylation of MCM2-S53 in H1299 cells (IC50 = 0.29 µM). LY3177833 reduces tumor growth in an SW620 human colorectal adenocarcinoma mouse xenograft model when administered at doses of...
Schlagworte: | (3R)-3-(5-fluoro-4-pyrimidinyl)-2,3-dihydro-3-methyl-6-(1H-pyrazol-4-yl)-1H-isoindol-1-one |
Anwendung: | Cdc7 kinase inhibitor |
CAS | 1627696-51-8 |
MW: | 309.3 D |
ab 125,00 €
Artikelnummer: NSJ-RQ4689
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA. This gene encodes Cell division cycle 7-related protein kinase, a cell division cycle protein with kinase activity that is critical for the G1/S transition. The yeast homolog is also essential for initiation of DNA replication as cell...
Schlagworte: | Anti-huCdc7, Anti-CDC7L1, Anti-HsCdc7, Anti-CDC7-related kinase, Anti-Cell division cycle 7-related protein kinase, CDC7... |
Anwendung: | WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
755,00 €
Artikelnummer: ARG41364.100
Protein function: Seems to phosphorylate critical substrates that regulate the G1/S phase transition and/or DNA replication. Can phosphorylates MCM2 and MCM3. [The UniProt Consortium]
Schlagworte: | Anti-CDC7, Anti-CDC7L1, Anti-HsCdc7, Anti-huCdc7, EC=2.7.11.1, Anti-CDC7-related kinase, Anti-Cell division cycle... |
Anwendung: | FC, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
624,00 €
Artikelnummer: BPS-100538
CDC7/DBF4 complex of human CDC7, also known as HsCDC7 and Hsk 1, GenBank Accession No. NM_003503 a.a. 1-574(end) with N-terminal GST-tag and MW= 94 kDa, and human DBF4, also known as ASK and CHIF, GenBank Accession No. NM_006716, a.a. 1-674(end) with N-terminal GST-tag and MW= 125 kDa, co-expressed expressed in an...
Schlagworte: | CDC7: HsCDC7, Hsk 1 DBF4: ASK, CHIF, |
Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
Exprimiert in: | insect cells |
Ursprungsart: | human |
MW: | 94 / 125 kD |
977,00 €
Artikelnummer: E-AB-18597.120
This gene encodes a cell division cycle protein with kinase activity that is critical for the G1/S transition. The yeast homolog is also essential for initiation of DNA replication as cell division occurs. Overexpression of this gene product may be associated with neoplastic transformation for some tumors. Multiple...
Schlagworte: | Anti-CDC7, Anti-huCdc7, Anti-HsCdc7, Anti-CDC7L1, EC=2.7.11.1, Anti-CDC7-related kinase, Anti-Cell division cycle... |
Anwendung: | WB, ELISA |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 71,00 €
Artikelnummer: Cay32519-1
Simurosertib is an inhibitor of cell division cycle 7 (Cdc7) kinase (IC50 = 0.26 nM). It is selective for Cdc7 over cyclin-dependent kinase 2 (Cdk2) and Rho-associated kinase 1 (ROCK1, IC50s = 6,300 and 430 nM, respectively). It inhibits phosphorylation of DNA replication licensing factor MCM2 in HeLa cells (IC50 =...
Schlagworte: | TAK-931, 2-(2S)-1-azabicyclo[2.2.2]oct-2-yl-6-(3-methyl-1H-pyrazol-4-yl)-thieno[3,2-d]pyrimidin-4(3H)-one |
Anwendung: | Cdc7 kinase inhibitor |
CAS | 1330782-76-7 |
MW: | 341.4 D |
ab 60,00 €
Artikelnummer: G-CAB5738.100
Anwendung: | WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 352,00 €