Zu "K02211" wurden 85 Artikel gefunden!
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Anti-Cyclin dependent kinase 9 / CDK9, clone GIH-3
Artikelnummer: NSJ-RQ8891
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA. Cyclin dependent kinase 9 (CDK9) is a serine/threonine kinase that forms part of the positive transcription elongation factor b (P-TEFb) complex. It plays a key role in regulating RNA polymerase II-mediated transcription by phosphorylating...
| Schlagworte: | Anti-CDK9, Anti-C-2K, Anti-Cyclin-dependent kinase 9, Anti-Cell division protein kinase 9, Anti-Serine/threonine-protein... |
| Anwendung: | WB, IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
Atuveciclib
Artikelnummer: Cay44337-10
Atuveciclib is an inhibitor of Cdk9/cyclin T1 (IC50 = 6 nM). It is selective for Cdk9/cyclin T1 over Cdk1/cyclin B, Cdk2/cyclin E, Cdk3/cyclin E, Cdk5/p35, Cdk6/cyclin D3, and Cdk7/cyclin H/Mat1 (IC50s = 1,100, 1,000, 890, 1,600, >10,000 and >10,000 nM, respectively). In vivo, atuveciclib (6. and 12. mg/kg) reduces...
| Schlagworte: | BAY-1143572 |
| Anwendung: | Cdk9/cyclin T1 inhibitor |
| CAS | 1414943-94-4 |
| MW: | 387.43 D |
ab 370,00 €
BAY-1251152
Artikelnummer: LKT-B030962.5
Inhibitor of PTEFb/CDK9.
| Schlagworte: | BAY 1251152, BAY1251152 |
| Anwendung: | CDK9 inhibitor |
| CAS | 1610358-56-9 |
| MW: | 404.44 D |
ab 123,00 €
Flavopiridol (hydrochloride)
Artikelnummer: Cay10009197-5
Flavopiridol is an orally bioavailable inhibitor of cyclin dependent kinases (IC50s = ~100, ~100, ~100, and 300 nM for Cdk1, Cdk2, Cdk4, and Cdk7, respectively). It also inhibits TEFb, a complex composed of Cdk9 and cyclin T1, with a Ki value of 3 nM. Flavopiridol inhibits transcription of a CMV promoter in HeLa...
| Schlagworte: | Alvocidib, HL 275, HMR 1275, L-868,275,... |
| CAS | 131740-09-5 |
| MW: | 438.3 D |
ab 73,00 €
Cdk9 Inhibitor
Artikelnummer: Cay42512-1
A Cdk9 inhibitor (IC50 = 39 nM), selective for Cdk9 over Cdk1-7 (IC50s = >1,000 nM for all), inhibits PRRSV replication in PRRSV-infected primary porcine alveolar macrophages at 6 to 200 nM. Formulation: A solid. InChI:...
| Schlagworte: | Cdk9 Inhibitor 1, Cdk9-IN-1, Cyclin-dependent Kinase 9 Inhibitor, Cyclin-dependent Kinase 9 Inhibitor-1, Cyclin-dependent... |
| Anwendung: | Cdk9 inhibitor |
| CAS | 1415559-43-1 |
| MW: | 499.54 D |
ab 44,00 €
Anti-CDK9
Artikelnummer: A303-492A
Protein function: Protein kinase involved in the regulation of transcription. Member of the cyclin-dependent kinase pair (CDK9/cyclin-T) complex, also called positive transcription elongation factor b (P-TEFb), which facilitates the transition from abortive to productive elongation by phosphorylating the CTD...
| Schlagworte: | Anti-C-2K, Anti-CDK9, Anti-CDC2L4, EC=2.7.11.22, EC=2.7.11.23, Anti-Cyclin-dependent kinase 9, Anti-Cell division protein... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
Anti-CDK9
Artikelnummer: A303-493A-T
Protein function: Protein kinase involved in the regulation of transcription. Member of the cyclin-dependent kinase pair (CDK9/cyclin-T) complex, also called positive transcription elongation factor b (P-TEFb), which facilitates the transition from abortive to productive elongation by phosphorylating the CTD...
| Schlagworte: | Anti-C-2K, Anti-CDK9, Anti-CDC2L4, EC=2.7.11.22, EC=2.7.11.23, Anti-Cyclin-dependent kinase 9, Anti-Cell division protein... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 165,00 €
CAY10574
Artikelnummer: Cay10011247-5
Cyclin-dependent kinases (CDKs) play a key role in regulating cell division by phosphorylating distinct substrates in different phases of the cell cycle. Cell cycle deregulation in many cancers often results from altered CDK activity. Thus, CDKs are potential pharmacological targets for anticancer agents. CAY10574...
| Schlagworte: | 4-[(3,5-diamino-1H-pyrazol-4-yl)azo]-phenol |
| Anwendung: | CDK9 inhibitor |
| CAS | 140651-18-9 |
| MW: | 218.2 D |
ab 38,00 €
SNS-032
Artikelnummer: Cay17904-1
Cyclin-dependent kinases (CDKs) are key regulators of cell cycle progression and are therefore promising targets for cancer therapy. SNS-032 is an ATP-competitive inhibitor of Cdk9, 2, and 7 with IC50 values of 4, 38, and 62 nM, respectively. It is selective for these kinases and displays no additional activity...
| Schlagworte: | BMS-387032, N-[5-[[[5-(1,1-dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-4-piperidinecarboxamide |
| Anwendung: | Cdk9 / Cdk2 / Cdk7 inhibitor |
| CAS | 345627-80-7 |
| MW: | 380.5 D |
ab 67,00 €
(±)-BAY-1251152
Artikelnummer: Cay35094-1
(±)-BAY-1251152 is a racemic mixture of the cyclin-dependent kinase 9 (Cdk9) inhibitor (+)-BAY-1251152 and its isomer (-)-BAY-1251152.Formal Name: 5-fluoro-4-(4-fluoro-2-methoxyphenyl)-N-[4-[(S-methylsulfonimidoyl)methyl]-2-pyridinyl]-2-pyridinamine. CAS Number: 1610358-53-6. Molecular Formula: C19H18F2N4O2S....
| Schlagworte: | 5-fluoro-4-(4-fluoro-2-methoxyphenyl)-N-[4-[(S-methylsulfonimidoyl)methyl]-2-pyridinyl]-2-pyridinamine |
| Anwendung: | Cdk9 inhibitor racemic mixture |
| CAS | 1610358-53-6 |
| MW: | 404.4 D |
ab 100,00 €
Dinaciclib
Artikelnummer: Cay14707-10
Cyclin-dependent kinases (CDKs) are critical positive regulators of cell cycle progression and cellular transcription whose dysregulation can lead to the development of cancer. Dinaciclib inhibits CDK1, CDK2, CDK5, and CDK9 activity in vitro with IC50 values of 3, 1, 1, and 4 nM, respectively. Compared to the...
| Schlagworte: | SCH 727965, 1-[3-ethyl-7-[[(1-oxido-3-pyridinyl)methyl]amino]pyrazolo[1,5-a]pyrimidin-5-yl]-2S-piperidineethanol |
| Anwendung: | CDK1 / CDK2 / CDK5 / CDK9 inhibitor |
| CAS | 779353-01-4 |
| MW: | 396.5 D |
ab 139,00 €
Anti-cdk9 (PITALRE, cdc Kinase Family, Cyclin-dependent...
Artikelnummer: 100-401-167
Protein function: Protein kinase involved in the regulation of transcription. Member of the cyclin-dependent kinase pair (CDK9/cyclin-T) complex, also called positive transcription elongation factor b (P-TEFb), which facilitates the transition from abortive to productive elongation by phosphorylating the CTD...
| Schlagworte: | Anti-CDK9, Anti-C-2K, Anti-CDC2L4, EC=2.7.11.22, EC=2.7.11.23, Anti-Cyclin-dependent kinase 9, Anti-Cell division protein... |
| Anwendung: | ELISA, IHC, IP, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat, mouse |
733,00 €