- Suchergebnis für K02208
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Zu "K02208" wurden 47 Artikel gefunden!
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NEU
Artikelnummer: ATA-AMAb91934.100
Monoclonal Antibody against Human CDK19, Clone ID: CL14114, Gene description: Cyclin dependent kinase 19, Alternative Gene Names: bA346C16.3, CDC2L6, CDK11, KIAA1028, Validated applications: ICC, WB, Uniprot ID: Q9BWU1, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C....
Anwendung: | ICC, WB |
Wirt: | Mouse |
Spezies-Reaktivität: | human |
ab 335,00 €
NEU
Artikelnummer: ATA-AMAb91935.100
Monoclonal Antibody against Human CDK19, Clone ID: CL14116, Gene description: Cyclin dependent kinase 19, Alternative Gene Names: bA346C16.3, CDC2L6, CDK11, KIAA1028, Validated applications: ICC, IHC, WB, Uniprot ID: Q9BWU1, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C....
Anwendung: | ICC, IHC, WB |
Wirt: | Mouse |
Spezies-Reaktivität: | human |
ab 335,00 €
NEU
Artikelnummer: Cay30291-1
Senexin A is an inhibitor of cyclin-dependent kinase 8 (Cdk8, IC50 = 0.28 µM). It also inhibits cyclin-dependent kinase inhibitor p21WAF1-induced reporter expression in reporter assay using HT-1080 p21-9 cells (IC50 = 0.68 µM). Senexin A (2.5 µM) prevents 17beta-estradiol-induced increases in expression of mRNA...
Schlagworte: | 4-[(2-phenylethyl)amino]-6-quinazolinecarbonitrile |
Anwendung: | Cdk8 inhibitor |
CAS | 1366002-50-7 |
MW: | 274.3 D |
ab 48,00 €
-10 %
Rabattaktion
Artikelnummer: ELK-ELK6827.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse CDK8. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse CDK8. Next,...
Schlagworte: | Cdk8, EC=2.7.11.22, EC=2.7.11.23, Cyclin-dependent kinase 8, Mediator complex subunit CDK8, Cell division protein kinase... |
Anwendung: | ELISA |
Spezies-Reaktivität: | mouse |
365,00 €
ab 328,50 €
-10 %
Rabattaktion
Artikelnummer: ELK-ELK4302.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human CDK8. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human CDK8. Next,...
Schlagworte: | CDK8, EC=2.7.11.22, EC=2.7.11.23, Protein kinase K35, Cyclin-dependent kinase 8, Mediator complex subunit CDK8, Cell... |
Anwendung: | ELISA |
Spezies-Reaktivität: | human |
365,00 €
ab 328,50 €
Artikelnummer: A302-501A
Protein function: Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is...
Schlagworte: | Anti-CDK8, EC=2.7.11.22, EC=2.7.11.23, Anti-Protein kinase K35, Anti-Cyclin-dependent kinase 8, Anti-Mediator complex... |
Anwendung: | WB, IP, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 164,00 €
Artikelnummer: A302-500A
Protein function: Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is...
Schlagworte: | Anti-CDK8, EC=2.7.11.22, EC=2.7.11.23, Anti-Protein kinase K35, Anti-Cyclin-dependent kinase 8, Anti-Mediator complex... |
Anwendung: | WB, IP |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 164,00 €
Artikelnummer: Cay18761-5
CCT251545 is an orally bioavailable inhibitor of Wnt signaling (IC50 = 5 nM). It is a potent and selective inhibitor of the human mediator complex-associated protein kinases Cdk8 and Cdk19. Through its effects on Cdk8 and Cdk19, CCT251545 alters Wnt pathway-regulated gene expression. It reduces tumor growth in COLO...
Schlagworte: | 8-[3-chloro-5-[4-(1-methyl-1H-pyrazol-4-yl)phenyl]-4-pyridinyl]-2,8-diazaspiro[4.5]decan-1-one |
Anwendung: | CDK8 / CDK19 inhibitor |
CAS | 1661839-45-7 |
MW: | 421.9 D |
ab 66,00 €
Artikelnummer: Cay28459-5
Senexin B is an inhibitor of Cdk8 and Cdk19. It inhibits Cdk8 with IC50 values ranging from 24 to 50 nM, depending on the assay used. It selectively inhibits Cdk19 and Cdk8 by 98.6 and 97.8%, respectively, in a panel of greater than 450 kinases at 2 µM but does inhibit MAP4K2 and YSK4 by 69 and 59%, respectively....
Schlagworte: | SNX2-1-165, 4-[[2-[6-[(4-methyl-1-piperazinyl)carbonyl]-2-naphthalenyl]ethyl]amino]-6-quinazolinecarbonitrile |
Anwendung: | Cdk8/Cdk19 inhibitor |
CAS | 1449228-40-3 |
MW: | 450.5 D |
ab 43,00 €
Artikelnummer: Cay29669-1
MSC2530818 is an orally bioavailable cyclin-dependent kinase 8 (Cdk8) inhibitor (IC50 = 2.6 nM). It is selective for Cdk8 over a panel of 264 kinases at 1 µM but does inhibit glycogen synthase kinase 3alpha (GSK3alpha, IC50 = 691 nM). MSC2530818 inhibits STAT1 phosphorylation in SW620 colorectal cancer cells with an...
Schlagworte: | [(2S)-2-(4-chlorophenyl)-1-pyrrolidinyl](3-methyl-1H-pyrazolo[3,4-b]pyridin-5-yl)-methanone |
Anwendung: | CDK8 inhibitor |
CAS | 1883423-59-3 |
MW: | 340.8 D |
ab 98,00 €
Artikelnummer: G-HUFI02304.96
Anwendung: | ELISA |
Spezies-Reaktivität: | human |
641,00 €
Artikelnummer: IHC-00704
Protein function: Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is...
Schlagworte: | Anti-CDK8, EC=2.7.11.22, EC=2.7.11.23, Anti-Protein kinase K35, Anti-Cyclin-dependent kinase 8, Anti-Mediator complex... |
Anwendung: | IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 164,00 €