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NEU
Anti-CDK19, clone CL14114
Anti-CDK19, clone CL14114

Artikelnummer: ATA-AMAb91934.100

Monoclonal Antibody against Human CDK19, Clone ID: CL14114, Gene description: Cyclin dependent kinase 19, Alternative Gene Names: bA346C16.3, CDC2L6, CDK11, KIAA1028, Validated applications: ICC, WB, Uniprot ID: Q9BWU1, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C....
Anwendung: ICC, WB
Wirt: Mouse
Spezies-Reaktivität: human
ab 335,00 €
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NEU
Anti-CDK19, clone CL14116
Anti-CDK19, clone CL14116

Artikelnummer: ATA-AMAb91935.100

Monoclonal Antibody against Human CDK19, Clone ID: CL14116, Gene description: Cyclin dependent kinase 19, Alternative Gene Names: bA346C16.3, CDC2L6, CDK11, KIAA1028, Validated applications: ICC, IHC, WB, Uniprot ID: Q9BWU1, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C....
Anwendung: ICC, IHC, WB
Wirt: Mouse
Spezies-Reaktivität: human
ab 335,00 €
Bewerten
NEU
Senexin A
Senexin A

Artikelnummer: Cay30291-1

Senexin A is an inhibitor of cyclin-dependent kinase 8 (Cdk8, IC50 = 0.28 µM). It also inhibits cyclin-dependent kinase inhibitor p21WAF1-induced reporter expression in reporter assay using HT-1080 p21-9 cells (IC50 = 0.68 µM). Senexin A (2.5 µM) prevents 17beta-estradiol-induced increases in expression of mRNA...
Schlagworte: 4-[(2-phenylethyl)amino]-6-quinazolinecarbonitrile
Anwendung: Cdk8 inhibitor
CAS 1366002-50-7
MW: 274.3 D
ab 48,00 €
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-10 %
Rabattaktion
Mouse CDK8 (Cyclin Dependent Kinase 8) ELISA Kit
Mouse CDK8 (Cyclin Dependent Kinase 8) ELISA Kit

Artikelnummer: ELK-ELK6827.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse CDK8. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse CDK8. Next,...
Schlagworte: Cdk8, EC=2.7.11.22, EC=2.7.11.23, Cyclin-dependent kinase 8, Mediator complex subunit CDK8, Cell division protein kinase...
Anwendung: ELISA
Spezies-Reaktivität: mouse
365,00 € ab 328,50 €
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-10 %
Rabattaktion
Human CDK8 (Cyclin Dependent Kinase 8) ELISA Kit
Human CDK8 (Cyclin Dependent Kinase 8) ELISA Kit

Artikelnummer: ELK-ELK4302.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human CDK8. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human CDK8. Next,...
Schlagworte: CDK8, EC=2.7.11.22, EC=2.7.11.23, Protein kinase K35, Cyclin-dependent kinase 8, Mediator complex subunit CDK8, Cell...
Anwendung: ELISA
Spezies-Reaktivität: human
365,00 € ab 328,50 €
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Anti-CDK8
Anti-CDK8

Artikelnummer: A302-501A

Protein function: Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is...
Schlagworte: Anti-CDK8, EC=2.7.11.22, EC=2.7.11.23, Anti-Protein kinase K35, Anti-Cyclin-dependent kinase 8, Anti-Mediator complex...
Anwendung: WB, IP, IHC
Wirt: Rabbit
Spezies-Reaktivität: human
ab 164,00 €
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Anti-CDK8
Anti-CDK8

Artikelnummer: A302-500A

Protein function: Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is...
Schlagworte: Anti-CDK8, EC=2.7.11.22, EC=2.7.11.23, Anti-Protein kinase K35, Anti-Cyclin-dependent kinase 8, Anti-Mediator complex...
Anwendung: WB, IP
Wirt: Rabbit
Spezies-Reaktivität: human
ab 164,00 €
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CCT251545
CCT251545

Artikelnummer: Cay18761-5

CCT251545 is an orally bioavailable inhibitor of Wnt signaling (IC50 = 5 nM). It is a potent and selective inhibitor of the human mediator complex-associated protein kinases Cdk8 and Cdk19. Through its effects on Cdk8 and Cdk19, CCT251545 alters Wnt pathway-regulated gene expression. It reduces tumor growth in COLO...
Schlagworte: 8-[3-chloro-5-[4-(1-methyl-1H-pyrazol-4-yl)phenyl]-4-pyridinyl]-2,8-diazaspiro[4.5]decan-1-one
Anwendung: CDK8 / CDK19 inhibitor
CAS 1661839-45-7
MW: 421.9 D
ab 66,00 €
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Senexin B
Senexin B

Artikelnummer: Cay28459-5

Senexin B is an inhibitor of Cdk8 and Cdk19. It inhibits Cdk8 with IC50 values ranging from 24 to 50 nM, depending on the assay used. It selectively inhibits Cdk19 and Cdk8 by 98.6 and 97.8%, respectively, in a panel of greater than 450 kinases at 2 µM but does inhibit MAP4K2 and YSK4 by 69 and 59%, respectively....
Schlagworte: SNX2-1-165, 4-[[2-[6-[(4-methyl-1-piperazinyl)carbonyl]-2-naphthalenyl]ethyl]amino]-6-quinazolinecarbonitrile
Anwendung: Cdk8/Cdk19 inhibitor
CAS 1449228-40-3
MW: 450.5 D
ab 43,00 €
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MSC2530818
MSC2530818

Artikelnummer: Cay29669-1

MSC2530818 is an orally bioavailable cyclin-dependent kinase 8 (Cdk8) inhibitor (IC50 = 2.6 nM). It is selective for Cdk8 over a panel of 264 kinases at 1 µM but does inhibit glycogen synthase kinase 3alpha (GSK3alpha, IC50 = 691 nM). MSC2530818 inhibits STAT1 phosphorylation in SW620 colorectal cancer cells with an...
Schlagworte: [(2S)-2-(4-chlorophenyl)-1-pyrrolidinyl](3-methyl-1H-pyrazolo[3,4-b]pyridin-5-yl)-methanone
Anwendung: CDK8 inhibitor
CAS 1883423-59-3
MW: 340.8 D
ab 98,00 €
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Human Cdk8 ELISA Kit
Human Cdk8 ELISA Kit

Artikelnummer: G-HUFI02304.96

Anwendung: ELISA
Spezies-Reaktivität: human
641,00 €
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Anti-CDK8 (IHC)
Anti-CDK8 (IHC)

Artikelnummer: IHC-00704

Protein function: Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is...
Schlagworte: Anti-CDK8, EC=2.7.11.22, EC=2.7.11.23, Anti-Protein kinase K35, Anti-Cyclin-dependent kinase 8, Anti-Mediator complex...
Anwendung: IHC
Wirt: Rabbit
Spezies-Reaktivität: human
ab 164,00 €
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