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Z-VDVAD-aminoluciferin
Artikelnummer: ABD-13215
Molecular weight: 912.99. Extinction coefficient (cm^-1 M^-1): 18000 Excitation (nm): 362. Emission (nm): 499. Z-VDVAD-aminoluciferin is a luminogenic substrate that measures caspase-2 activity in apoptotic cells. Caspases, a family of aspartate-specific cysteine proteases, are key regulators of apoptosis,...
| Anwendung: | Luminogenic caspase-2 substrate |
| MW: | 912.99 D |
1.810,00 €
FAM-FLICA(R) Caspase 2 Assay Kit
Artikelnummer: ICT-918
This kits makes use of a cell-permeant green fluorecent probe (FAM-VDVAD-FMK ) that binds to active caspase-2 in living cells undergoing apoptosis. Excitation wavelength 488-492nm, emission 515-535nm.
| Anwendung: | FM, FC, Apoptosis detection |
310,00 €
FAM-FLICA(R) Caspase 2 Assay Kit
Artikelnummer: ICT-919
This kits makes use of a cell-permeant green fluorecent probe (FAM-VDVAD-FMK ) that binds to active caspase-2 in living cells undergoing apoptosis. Excitation wavelength 488-492nm, emission 515-535nm.
| Anwendung: | FM, FC, Apoptosis detection |
883,00 €
Ac-VDVAD-AFC (trifluoroacetate salt)
Artikelnummer: Cay37351-5
Ac-VDVAD-AFC is a fluorogenic substrate for caspase-2. Upon enzymatic cleavage by caspase-2, 7-amino-4-trifluoromethylcoumarin (AFC) is released and its fluorescence can be used to quantify caspase-2 activity. AFC displays excitation/emission maxima of 400/505 nm, respectively.Formal Name:...
| Schlagworte: | Caspase-2 Substrate (Fluorogenic), N-Acetyl-Val-Asp-Val-Ala-Asp-7-amino-4-Trifluoromethylcoumarin,... |
| Anwendung: | Fluorogenic caspase-2 substrate |
| MW: | 770.7 D |
ab 69,00 €
Anti-Caspase-2, clone 10C6
Artikelnummer: AG-20T-0135-C100
Caspase-2 is a Class I caspase with a long prodomain necessary for nuclear localization. Upon activation of the apoptotic pathway, the procaspase is cleaved into smaller fragments. Caspase-2 is the nuclear apoptotic respondent to cellular genotoxic stress or mitotic catastrophe and is involved in the activation...
| Schlagworte: | Anti-ICH1, Anti-CASP2, EC=3.4.22.55 |
| Anwendung: | ELISA, FC, ICC, IHC |
| Wirt: | Rat |
| Spezies-Reaktivität: | dog, human, monkey, mouse, rat |
380,00 €
Anti-Caspase-2, clone 11B4
Artikelnummer: AG-20T-0136-C100
Caspase-2 is a Class I caspase with a long prodomain necessary for nuclear localization. Upon activation of the apoptotic pathway, the procaspase is cleaved into smaller fragments. Caspase-2 is the nuclear apoptotic respondent to cellular genotoxic stress or mitotic catastrophe and is involved in the activation...
| Schlagworte: | Anti-ICH1, Anti-CASP2, EC=3.4.22.55 |
| Anwendung: | IP, WB |
| Wirt: | Rat |
| Spezies-Reaktivität: | dog, human, monkey, mouse, rat |
380,00 €
Anti-Caspase-2 (ICH-1, Nedd2)
Artikelnummer: 600-401-412
Protein function: Involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival. [The UniProt Consortium]
| Schlagworte: | Anti-Ich1, Anti-Casp2, EC=3.4.22.55 |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | mouse, rat |
684,00 €
Anti-Caspase-2
Artikelnummer: NSJ-R30278
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Caspase-2/CASP2, which is involved in stress-induced apoptosis, is recruited into a large protein complex, the molecular composition of which remains elusive. Activation of Caspase-2 occurs in a complex that contains the death domain-containing protein PIDD,...
| Schlagworte: | Anti-ICH1, Anti-CASP2, EC=3.4.22.55, Caspase-2 Antibody |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
755,00 €
Anti-Caspase-2
Artikelnummer: NSJ-R32097
0.5mg/ml if reconstituted with 0.2ml sterile DI water. CASP2 is equal to Caspase-2. And Caspase-2, which is involved in stress-induced apoptosis, is recruited into a large protein complex, the molecular composition of which remains elusive. It is showed that activation of caspase-2 occurs in a complex that contains...
| Schlagworte: | Anti-ICH1, Anti-CASP2, EC=3.4.22.55, Caspase-2 Antibody |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
755,00 €
Z-VDVAD-FMK
Artikelnummer: BPS-27668-1
Z-VDVAD-FMK is a synthetic peptide that irreversibly inhibits the activity of caspase-2. It attenuates oxyhemoglobin-induced cleavage of PARP and apoptosis in endothelial cells. Z-VDVAD-FMK can be used for both in vitro and in vivo studies--see note for using this product in vitro.
| Schlagworte: | Z-VDVAD-fluoromethylketone, Caspase-2 Inhibitor (fluoromethylketone), |
| Anwendung: | Irreversible Caspase-2 inhibitor |
| MW: | 695.7 D |
ab 800,00 €
Anti-CASP2
Artikelnummer: E-AB-10051.120
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of...
| Schlagworte: | Anti-ICH1, Anti-CASP2, EC=3.4.22.55, CASP2 Polyclonal Antibody |
| Anwendung: | WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 71,00 €
Anti-Caspase-2
Artikelnummer: NSJ-F42862-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. CASP2 is a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. The protein exist as inactive proenzymes which undergo proteolytic processing at...
| Schlagworte: | Anti-ICH1, Anti-CASP2, EC=3.4.22.55, Caspase-2 Antibody |
| Anwendung: | WB, IHC, FC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 326,00 €