Zu "K02161" wurden 284 Artikel gefunden!
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AZD4320
Artikelnummer: LKT-A990144.1
AZD4320 is an inhibitor that targets Bcl-2 and Bcl-xl. It has been found to kill tumor cells in vitro. SMILES: CN(CCC(CSC1=CC=CC=C1)NC2=C(C=C(C=C2)S(=O)(=O)NC(=O)C3=CC=C(C=C3)N4CCC(CC4)C(C5=CC=CC=C5C6=CC=C(C=C6)Cl)O)S(=O)(=O)C(F)(F)F)CCO
| Schlagworte: | AZD-4320, UNII-LH1ZTY91OR, LH1ZTY91OR,... |
| Anwendung: | Inhibitor of Bcl-2 and Bcl-xL |
| CAS | 1357576-48-7 |
| MW: | 945.53 D |
ab 153,00 €
Anti-BCL2
Artikelnummer: ABS-KC-481.100
Protein function: Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing...
| Schlagworte: | Anti-Apoptosis regulator Bcl-2, BCL2 Antibody |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 232,00 €
BCL2 (human), recombinant protein
Artikelnummer: ABS-PP-151.20
| Schlagworte: | Apoptosis regulator Bcl-2, Recombinant Human BCL2 Protein |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 20.5 kD |
ab 90,00 €
Anti-BCL2
Artikelnummer: ABS-KC-6444.100
Protein function: Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing...
| Schlagworte: | Anti-Apoptosis regulator Bcl-2, BCL2 Antibody |
| Wirt: | Mouse |
| Spezies-Reaktivität: | chicken, human |
ab 232,00 €
Anti-Bcl-2
Artikelnummer: E-AN006000L.100
BCL2 (BCL2 Apoptosis Regulator) is a Protein Coding gene. Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases....
| Schlagworte: | Anti-Bcl2, Anti-Bcl-2, Anti-Apoptosis regulator Bcl-2, Bcl-2 Polyclonal Antibody |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 109,00 €
Sabutoclax
Artikelnummer: TGM-T6650-100mg
Description: Sabutoclax (BI-97C1)(BI-97C1) is a pan-Bcl-2 inhibitor, including Bcl-xL, Bcl-2, Mcl-1 and Bfl-1 with IC50 of 0.31 µM, 0.32 µM, 0.20 µM and 0.62 µM, respectively. Target: BCL. Smiles: CC(CNC(=O)c1c(O)c(O)cc2c(O)c(c(C)cc12)-c1c(C)cc2c(C(=O)NC[C@H](C)c3ccccc3)c(O)c(O)cc2c1O)c1ccccc1. References: Yunhui...
| Schlagworte: | BI-97C1 |
| Anwendung: | Pan-Bcl-2 inhibitor |
| CAS | 1228108-65-3 |
| MW: | 700.78 D |
ab 63,00 €
BDA-366
Artikelnummer: TGM-T6778-100mg
Description: BDA-366, a potent Bcl2 antagonist, selectively binds the Bcl2-BH4 domain with high affinity (Ki = 3.3 nM), inducing a conformational change that nullifies its antiapoptotic function, thereby transforming it into a pro-apoptotic entity. This compound effectively suppresses lung cancer cell growth[1]....
| Anwendung: | Bcl2-BH4 domain antagonist |
| CAS | 1909226-00-1 |
| MW: | 423.5 D |
ab 46,00 €
Oblimersen
Artikelnummer: TGM-T64275-100mg
Description: Oblimersen is a BCL-2 inhibitor that targets BCL-2 RNA by specifically binding to the first six codons of the BCL-2 mRNA sequence, thereby degrading BCL-2 mRNA and inducing apoptosis through the down-regulation of BCL-2 expression. Target: Others
| Anwendung: | Targets apoptosis regulator Bcl-2 (BCL2) |
| CAS | 190977-41-4 |
ab 1.520,00 €
ABT-263
Artikelnummer: Cay11500-5
ABT-263 is an inhibitor of the Bcl-2 family proteins Bcl-2, Bcl-xL, and Bcl-W (Kis = is = 550 and 354 nM, respectively). ABT-263 is cytotoxic in a panel of small cell lung cancer (SCLC), leukemia, and lymphoma cell lines with a mean EC50 value of 1 µM. It induces apoptosis in influenza A-infected retinal pigment...
| Schlagworte: | A-855071, Navitoclax,... |
| Anwendung: | Potent, cell-permeable BH3 domain mimetic |
| CAS | 923564-51-6 |
| MW: | 974.6 D |
ab 35,00 €
Aranorosin
Artikelnummer: TGM-T37444-1mg
Description: Aranorosin is a fungal metabolite originally isolated from P. roseus. It has antimicrobial activity against B. subtilis, A. niger, and C. albicans when used at a concentration of 1 mg/ml. Aranorosin also reduces viability in apoptosis-resistant HeLa/Bcl-2 cells. Target: Others. Smiles:...
| Anwendung: | Antibiotic |
| CAS | 117184-53-9 |
| MW: | 419.518 D |
ab 214,00 €
Thymoquinone
Artikelnummer: TGM-T4088-1mL
Description: Thymoquinone (NSC 2228) is a compound be found in herbs and spices with anti-inflammatory and anti-oxidant effects. Target: BCL. Smiles: CC(C)C1=CC(=O)C(C)=CC1=O. References: Randhawa, M.A., and Alghamdi, M.S. Anticancer activity of Nigella sativa (black seed) - A review. Am.J.Chin.Med. 39(6), 1075-1091...
| Schlagworte: | Thymoquinon, NSC 2228 |
| Anwendung: | Apoptosis inducer |
| CAS | 490-91-5 |
| MW: | 164.2 D |
ab 30,00 €
Obatoclax Mesylate
Artikelnummer: TGM-T6275-100mg
Description: Obatoclax Mesylate (GX15-070) is a Bcl-2 antagonist (Ki: 0.22 µM) and can induce apoptosis with up-regulation of Bim, induced cytochrome c release, and activation of caspase-3. Target: Autophagy, Parasite, BCL. Smiles: CS(O)(=O)=O.COc1cc([nH]c1=Cc1[nH]c(C)cc1C)=C1C=c2ccccc2=N1. References: Nguyen M,...
| Schlagworte: | GX15-070, Obatoclax |
| Anwendung: | Targets apoptosis regulator Bcl-2 (BCL2) |
| CAS | 803712-79-0 |
| MW: | 413.49 D |
ab 43,00 €