Zu "K02159" wurden 154 Artikel gefunden!
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Bax Channel Blocker
Artikelnummer: Cay37538-10
Bax channel blocker is an inhibitor of Bax. It binds to Bax in a cell-free assay (Kd = 15 µM) and inhibits Bax-mediated membrane permeabilization induced by the membrane-targeted death ligand tBID in a liposomal release assay (IC50 = 3.3 µM). Bax channel blocker inhibits apoptosis induced by TNF-alpha- and the...
| Schlagworte: | BAI1, 3,6-dibromo-alpha-(1-piperazinylmethyl)-9H-carbazole-9-ethanol |
| Anwendung: | Bax inhibitor |
| CAS | 335165-68-9 |
| MW: | 467.2 D |
ab 44,00 €
Cattle Bax (Bcl2 Associated X Protein) ELISA Kit
Artikelnummer: ELK-ELK8017.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Cattle Bax. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Cattle Bax. Next,...
| Schlagworte: | BAX, Apoptosis regulator BAX |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | cattle |
ab 470,00 €
Mouse Bax (Bcl2 Associated X Protein) ELISA Kit
Artikelnummer: ELK-ELK4278.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse Bax. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse Bax. Next,...
| Schlagworte: | Bax, Apoptosis regulator BAX |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
ab 365,00 €
Human Bax (Bcl2 Associated X Protein) ELISA Kit
Artikelnummer: ELK-ELK1532.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human Bax. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human Bax. Next,...
| Schlagworte: | BAX, BCL2L4, Bcl2-L-4, Bcl-2-like protein 4, Apoptosis regulator BAX |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €
BTSA1
Artikelnummer: Cay37305-10
BTSA1 is an activator of Bax. It binds to the Bax N-terminal activation site, also known as the trigger site (IC50 = 250 nM), and induces Bax translocation membrane permeabilization in liposomes when used at concentrations ranging from 100 to 400 nM. BTSA1 (0.1-1 µM) induces apoptosis in various human and mouse...
| Schlagworte: | Bax Trigger Site Activator 1, 3-phenyl-1-(4-phenyl-2-thiazolyl)-1H-pyrazole-4,5-dione, 4-[2-(2-thiazolyl)hydrazone] |
| Anwendung: | Bax activator |
| CAS | 314761-14-3 |
| MW: | 430.5 D |
ab 109,00 €
Anti-BAX, clone SP47
Artikelnummer: 200-C01-B34
Protein function: Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that...
| Schlagworte: | Anti-BAX, Anti-BCL2L4, Anti-Bcl2-L-4, Anti-Bcl-2-like protein 4, Anti-Apoptosis regulator BAX |
| Anwendung: | ELISA, FC, IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
641,00 €
Thymoquinone
Artikelnummer: Cay15039-5
The black seeds of Nigella have long been ingested to treat a broad range of diseases, including inflammation and cancer. Thymoquinone is a natural phytochemical isolated from the seeds of N. sativa. It has anti-inflammatory effects, blocking the synthesis of leukotrienes. Thymoquinone inhibits the growth of...
| Schlagworte: | NSC 2228, 2-methyl-5-(1-methylethyl)-2,5-cyclohexadiene-1,4-dione |
| Anwendung: | Apoptosis inducer |
| CAS | 490-91-5 |
| MW: | 164.2 D |
ab 43,00 €
BAM7
Artikelnummer: Cay14566-1
BAM7 is a direct activator of Bax (EC50 = 3.3 µM) that engages the Bax trigger site and promotes the functional oligomerization of Bax. It is selective for the BH3 binding site on Bax and does not interact with BH3 binding pockets on other proteins. BAM7 induces Bax-dependent cell death in mouse embryo...
| Schlagworte: | Bax Activator Molecule 7, 3-methyl-1-(4-phenyl-2-thiazolyl)-1H-pyrazole-4,5-dione 4-[2-(2-ethoxyphenyl)hydrazone] |
| Anwendung: | Bax activator, Bax oligomerization inducer |
| CAS | 331244-89-4 |
| MW: | 405.5 D |
ab 43,00 €
Anti-Bax Polyclonal Antibody
Artikelnummer: ABE-39-2027-100
Apoptosis regulator BAX, also known as bcl-2-like protein 4, is a protein that in humans is encoded by the BAX gene. The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as Anti-or pro-apoptotic regulators that are involved in a wide variety of...
| Schlagworte: | Anti-BAX, Anti-BCL2L4, Anti-Bcl2-L-4, Anti-Bcl-2-like protein 4, Anti-Apoptosis regulator BAX, Anti-Bax Polyclonal Antibody |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat |
801,00 €
Anti-Bax, clone G26-R
Artikelnummer: ARG10552.50
Protein function: Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that...
| Schlagworte: | Anti-BAX, Anti-BCL2L4, Anti-Bcl2-L-4, Anti-Bcl-2-like protein 4, Anti-Apoptosis regulator BAX |
| Anwendung: | WB, IP, ELISA, IHC (paraffin), IHC (frozen), ICC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
592,00 €
Anti-Bax (FITC), clone T22-A
Artikelnummer: ARG10553.50
Protein function: Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that...
| Schlagworte: | Anti-BAX, Anti-BCL2L4, Anti-Bcl2-L-4, Anti-Bcl-2-like protein 4, Anti-Apoptosis regulator BAX |
| Anwendung: | FC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
696,00 €
Anti-Bax, clone 2D2
Artikelnummer: ARG21418.50
Protein function: Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that...
| Schlagworte: | Anti-BAX, Anti-BCL2L4, Anti-Bcl2-L-4, Anti-Bcl-2-like protein 4, Anti-Apoptosis regulator BAX |
| Anwendung: | WB, IP, FC, IHC (paraffin), ICC, IF, FA (Neutr.), Purification |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, monkey, dog, bovine |
480,00 €