Zu "K02145" wurden 31 Artikel gefunden!
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EN6
Artikelnummer: Cay28715-5
EN6 is an activator of autophagy. It inhibits mammalian target of rapamycin complex 1 (mTORC1) signaling by binding covalently to cysteine 277 of the ATP6V1A catalytic subunit of the lysosomal vacuolar ATPase (v-ATPase) and impairing v-ATPase coupling with Rag GTPases. It is selective for inhibition of mTORC1 over...
| Schlagworte: | N-[4-fluoro-3-[(1-oxo-2-propen-1-yl)amino]phenyl]-1-(2-fluorophenyl)-1H-pyrazole-4-carboxamide |
| Anwendung: | Autophagy activator, mTORC1 inhibitor |
| CAS | 1808714-73-9 |
| MW: | 368.3 D |
ab 116,00 €
Anti-ATP6V1A
Artikelnummer: A305-193A
Protein function: Catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. [The UniProt Consortium]
| Schlagworte: | Anti-ATP6A1, Anti-ATP6V1A, EC=3.6.3.14, Anti-V-ATPase subunit A, Anti-V-ATPase 69 kDa subunit, Anti-Vacuolar ATPase... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 178,00 €
Anti-ATP6V1A
Artikelnummer: A305-194A
Protein function: Catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. [The UniProt Consortium]
| Schlagworte: | Anti-ATP6A1, Anti-ATP6V1A, EC=3.6.3.14, Anti-V-ATPase subunit A, Anti-V-ATPase 69 kDa subunit, Anti-Vacuolar ATPase... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 178,00 €
Bafilomycin C1
Artikelnummer: Cay19625-5
Bafilomycin C1 is a bacterial metabolite that has been found in Streptomyces and has diverse biological activities. It inhibits the activities of vacuolar H+-ATPases (V-ATPases) and Na+/K+-ATPases in a concentration-dependent manner. Bafilomycin C1 (1 mg/ml) is active against a panel of 24 fungi in a disc assay. It...
| Schlagworte: | 2-Demethyl-2-methoxy-24-methyl-hygrolidin, L-681,110A1, 2E-butenedioic... |
| Anwendung: | V-ATPase inhibitor |
| CAS | 88979-61-7 |
| MW: | 720.9 D |
ab 111,00 €
Anti-ATP6V1A
Artikelnummer: ARG57716.100
Protein function: Catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl...
| Schlagworte: | Anti-ATP6A1, Anti-ATP6V1A, EC=3.6.3.14, Anti-V-ATPase subunit A, Anti-V-ATPase 69 kDa subunit, Anti-Vacuolar ATPase... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
658,00 €
Manzamine A
Artikelnummer: LKT-M0255.1
Manzamine A is an alkaloid isolated from marine sponges. Manzamine A exhibits neuroprotective, anticancer, anti-hyperlipidemic, anti-atherosclerotic, antibiotic, and antiviral activities. In vitro, manzamine A uncouples vacuolar ATPases, inhibiting autophagy and tumor growth. Manzamine A inhibits foam cell formation...
| Schlagworte: | Keramamine A, Manzamine A |
| Anwendung: | Vacuolar ATPase inhibitor |
| CAS | 104196-68-1 |
| MW: | 548.76 D |
468,00 €
Anti-ATP6V1A
Artikelnummer: ATA-HPA035083.100
Protein function: Catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl...
| Schlagworte: | Anti-ATP6A1, Anti-ATP6V1A, EC=7.1.2.2, Anti-V-ATPase subunit A, Anti-V-ATPase 69 kDa subunit, Anti-Vacuolar ATPase isoform... |
| Anwendung: | ICC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 239,00 €
Anti-ATP6V1A
Artikelnummer: ATA-HPA035084.100
Protein function: Catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl...
| Schlagworte: | Anti-ATP6A1, Anti-ATP6V1A, EC=7.1.2.2, Anti-V-ATPase subunit A, Anti-V-ATPase 69 kDa subunit, Anti-Vacuolar ATPase isoform... |
| Anwendung: | ICC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 239,00 €
Anti-ATP6V1A / V-ATPase subunit A
Artikelnummer: NSJ-RQ6823
0.5mg/ml if reconstituted with 0.2ml sterile DI water. V-type proton ATPase catalytic subunit A is an enzyme that in humans is encoded by the ATP6V1A gene. This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase...
| Schlagworte: | Anti-ATP6A1, Anti-ATP6V1A, Anti-V-ATPase subunit A, Anti-V-ATPase 69 kDa subunit, Anti-Vacuolar ATPase isoform VA68,... |
| Anwendung: | WB, IHC (paraffin), IF, FC, Direct ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
772,00 €
Anti-CVA69.24
Artikelnummer: CSB-PA002396XA01GHB.2
Make to order. Production time: 70-80 business days. Deliverables: 1. 200 µg antigen (used as positive control), 2. 1 ml pre-immune serum (used as negative control) , 3. Rabbit polyclonal antibody, antigen affinity purified. Quality Guarantee: 1. Antibody purity > 90% confirmed by SDS-PAGE, 2. Antibody titer > 1:...
| Schlagworte: | Anti-CVA69.24, EC=7.1.2.2, Anti-V-ATPase subunit A, Anti-V-ATPase 69 kDa subunit, Anti-Vacuolar proton pump subunit alpha,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | Gossypium hirsutum (Upland cotton) (Gossypium mexicanum) |
ab 1.529,00 €
Anti-VMA1
Artikelnummer: CSB-PA002396XA01SVG.2
Make to order. Production time: 70-80 business days. Deliverables: 1. 200 µg antigen (used as positive control), 2. 1 ml pre-immune serum (used as negative control) , 3. Rabbit polyclonal antibody, antigen affinity purified. Quality Guarantee: 1. Antibody purity > 90% confirmed by SDS-PAGE, 2. Antibody titer > 1:...
| Schlagworte: | Anti-CLS8, Anti-D1286, Anti-YDL185W, EC=3.1.-.-, VMA1 Antibody |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
ab 1.529,00 €
Anti-vma1
Artikelnummer: CSB-PA002396XA01SXV.2
Make to order. Production time: 70-80 business days. Deliverables: 1. 200 µg antigen (used as positive control), 2. 1 ml pre-immune serum (used as negative control) , 3. Rabbit polyclonal antibody, antigen affinity purified. Quality Guarantee: 1. Antibody purity > 90% confirmed by SDS-PAGE, 2. Antibody titer > 1:...
| Schlagworte: | Anti-V-ATPase subunit A, Anti-V-ATPase 67 kDa subunit, Anti-Vacuolar proton pump subunit alpha, Anti-V-type proton ATPase... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
ab 1.529,00 €