Zu "K02091" wurden 57 Artikel gefunden!
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Human CDK6 (Cyclin Dependent Kinase 6) ELISA Kit
Artikelnummer: ELK-ELK4270.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human CDK6. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human CDK6. Next,...
| Schlagworte: | CDK6, CDKN6, EC=2.7.11.22, Cyclin-dependent kinase 6, Cell division protein kinase 6, Serine/threonine-protein kinase PLSTIRE |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €
LEE011
Artikelnummer: Cay17666-10
LEE011 is a cyclin-dependent kinase (CDK) inhibitor that targets cyclin D1/CDK4 and cyclin D3/CDK6 at nanomolar concentrations. It inhibits retinoblastoma protein phosphorylation, which prevents CDK-mediated G1-S phase transition, arresting the cell cycle in the G1 phase, suppressing DNA synthesis, and inhibiting...
| Schlagworte: | Ribociclib, 7-cyclopentyl-N,N-dimethyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide |
| Anwendung: | Cyclin D1/CDK4 & cyclin D3/CDK6 inhibitor |
| CAS | 1211441-98-3 |
| MW: | 434.5 D |
ab 54,00 €
PD 0332991 (hydrochloride)
Artikelnummer: Cay16273-10
PD 0332991 is an orally active, selective inhibitor of the cyclin D kinases Cdk4 (IC50 = 11 nM) and Cdk6 (IC50= 16 nM) with no activity against a panel of 36 additional protein kinases. It has been reported to have antiproliferative activity against retinoblastoma-positive tumor cells, blocking retinoblastoma...
| Schlagworte: | Palbociclib, 6-acetyl-8-cyclopentyl-5-methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]-pyrido[2,3-d]pyrimidin-7(8H)-one,... |
| Anwendung: | Cyclin-dependent kinase 4/6 (CDK4/6) inhibitor |
| CAS | 827022-32-2 |
| MW: | 484 D |
ab 50,00 €
Anti-phospho-CDK6 (Tyr24)
Artikelnummer: ARG51830.50
Protein function: Serine/threonine-protein kinase involved in the control of the cell cycle and differentiation, promotes G1/S transition. Phosphorylates pRB/RB1 and NPM1. Interacts with D-type G1 cyclins during interphase at G1 to form a pRB/RB1 kinase and controls the entrance into the cell cycle. Involved in...
| Schlagworte: | Anti-phospho-CDK6, Anti-phospho-CDKN6, EC=2.7.11.22, Anti-phospho-Cyclin-dependent kinase 6, Anti-phospho-Cell division... |
| Anwendung: | WB, IHC (paraffin), ICC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 436,00 €
Anti-CDK6
Artikelnummer: A304-937A
Protein function: Serine/threonine-protein kinase involved in the control of the cell cycle and differentiation, promotes G1/S transition. Phosphorylates pRB/RB1 and NPM1. Interacts with D-type G1 cyclins during interphase at G1 to form a pRB/RB1 kinase and controls the entrance into the cell cycle. Involved in...
| Schlagworte: | Anti-CDK6, Anti-CDKN6, EC=2.7.11.22, Anti-Cyclin-dependent kinase 6, Anti-Cell division protein kinase 6,... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 164,00 €
Palbociclib
Artikelnummer: LKT-P014442.10
CDK4/6 inhibitor.
| Schlagworte: | PD-0332991, PD0332991 |
| Anwendung: | Cyclin-dependent kinase 4/6 (CDK4/6) inhibitor |
| CAS | 571190-30-2 |
| MW: | 447.54 D |
ab 149,00 €
Palbociclib Hydrochloride
Artikelnummer: LKT-P0244.5
Palbociclib, also known as PD0332991, is an orally available pyridopyrimidine-derived cyclin-dependent kinase (CDK) inhibitor with potential antineoplastic activity. PD-0332991 selectively inhibits cyclin-dependent kinases (particularly Cdk4/cyclin D1 kinase), which may inhibit retinoblastoma (Rb) protein...
| Schlagworte: | PD-033291, PD0332991,... |
| Anwendung: | Cdk4 / Cdk6 inhibitor |
| CAS | 827022-32-2 |
| MW: | 484 D |
ab 60,00 €
LY2835219
Artikelnummer: Cay21560-1
LY2835219 is an orally bioavailable dual inhibitor of cyclin-dependent kinase 4 (Cdk4) and Cdk6 (IC50s = 2 and 10 nM, respectively). Through this mechanism, it blocks phosphorylation of retinoblastoma protein, resulting in arrest of cell cycling in the G1 phase. LY2835219 has antitumor action against xenografts when...
| Schlagworte: | N-[5-[(4-ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-2-... |
| Anwendung: | Antineoplastic, Cyclin-dependent kinase (CDK) inhibitor |
| CAS | 1231929-97-7 |
| MW: | 506.6 D |
ab 50,00 €
Anti-phospho-CDK6 (Tyr13)
Artikelnummer: ARG51829.100
Protein function: Serine/threonine-protein kinase involved in the control of the cell cycle and differentiation, promotes G1/S transition. Phosphorylates pRB/RB1 and NPM1. Interacts with D-type G1 cyclins during interphase at G1 to form a pRB/RB1 kinase and controls the entrance into the cell cycle. Involved in...
| Schlagworte: | Anti-phospho-CDK6, Anti-phospho-CDKN6, EC=2.7.11.22, Anti-phospho-Cyclin-dependent kinase 6, Anti-phospho-Cell division... |
| Anwendung: | ICC, IF, IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 436,00 €
Human Cdk6 ELISA Kit
Artikelnummer: G-HUFI02302.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
641,00 €
Palbociclib Isethionate
Artikelnummer: LKT-P0344.10
CDK4/6 inhibitor.
| Schlagworte: | PD0332991-0054, PF00080665-73 |
| Anwendung: | CDK4/6 inhibitor |
| CAS | 827022-33-3 |
| MW: | 573.66 D |
ab 97,00 €
Anti-Cdk6
Artikelnummer: NSJ-R31239
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Cell division protein kinase 6, also called Pistire, is an enzyme that in humans is encoded by the CDK6 gene. The protein encoded by this gene is a member of the cyclin-dependent protein kinase(CDK) family. Radiation hybrid analysis and inclusion within a mapped...
| Schlagworte: | Anti-CRK2, Anti-Cdk6, Anti-Cdkn6, EC=2.7.11.22, Anti-CR2 protein kinase, Anti-Cyclin-dependent kinase 6, Anti-Cell... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat, mouse |
755,00 €