Zu "K02090" wurden 64 Artikel gefunden!
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Mouse CDK5 (Cyclin Dependent Kinase 5) ELISA Kit
Artikelnummer: ELK-ELK7636.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse CDK5. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse CDK5. Next,...
| Schlagworte: | EC=2.7.11.1, TPKII catalytic subunit, Cyclin-dependent kinase 5, Cell division protein kinase 5, Cyclin-dependent-like... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
ab 365,00 €
Human CDK5 (Cyclin Dependent Kinase 5) ELISA Kit
Artikelnummer: ELK-ELK2095.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human CDK5. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human CDK5. Next,...
| Schlagworte: | EC=2.7.11.1, TPKII catalytic subunit, Cyclin-dependent kinase 5, Cell division protein kinase 5, Cyclin-dependent-like... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €
Rat CDK5 (Cyclin Dependent Kinase 5) ELISA Kit
Artikelnummer: ELK-ELK4419.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat CDK5. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat CDK5. Next,...
| Schlagworte: | EC=2.7.11.1, TPKII catalytic subunit, Cyclin-dependent kinase 5, Cell division protein kinase 5, Cyclin-dependent-like... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | rat |
ab 365,00 €
Indirubin
Artikelnummer: LKT-I5212.5
Indirubin is a bisindole isomer of indigo, naturally sourced from Indigo naturalis. Indirubin exhibits anti-inflammatory, anti-angiogenic, and anticancer chemotherapeutic activities. In vivo, indirubin decreases levels of IgE and production of inflammatory cytokines, decreasing overall inflammation as well as skin...
| Anwendung: | CDK inhibitor |
| CAS | 479-41-4 |
| MW: | 262.26 D |
ab 104,00 €
Dinaciclib
Artikelnummer: Cay14707-5
Cyclin-dependent kinases (CDKs) are critical positive regulators of cell cycle progression and cellular transcription whose dysregulation can lead to the development of cancer. Dinaciclib inhibits CDK1, CDK2, CDK5, and CDK9 activity in vitro with IC50 values of 3, 1, 1, and 4 nM, respectively. Compared to the...
| Schlagworte: | SCH 727965, 1-[3-ethyl-7-[[(1-oxido-3-pyridinyl)methyl]amino]pyrazolo[1,5-a]pyrimidin-5-yl]-2S-piperidineethanol |
| Anwendung: | CDK1 / CDK2 / CDK5 / CDK9 inhibitor |
| CAS | 779353-01-4 |
| MW: | 396.5 D |
ab 125,00 €
SR 1664
Artikelnummer: Cay11086-10
Apart from direct peroxisome proliferator-activated receptor gamma (PPARgamma) agonism, several PPARgamma ligands have recently been shown to exert anti-diabetic effects through a second, distinct biochemical function: blocking the obesity-linked phosphorylation of PPARgamma by cyclin-dependent kinase 5 (Cdk5) at...
| Schlagworte: | 4'-[[2,3-dimethyl-5-[[[(1S)-1-(4-nitrophenyl)ethyl]amino]carbonyl]-1H-indol-1-yl]methyl]-[1,1'-biphenyl]-2-carboxylic acid |
| Anwendung: | Blocks phosphorylation of PPARgamma by Cdk5 |
| CAS | 1338259-05-4 |
| MW: | 547.6 D |
ab 61,00 €
Butyrolactone I
Artikelnummer: BVT-0448-M005
White to off-white solid. Soluble in DMSO, methanol, ethanol or acetone. Isolated from Aspergillus terreus. Cell permeable, potent and selective cyclin-dependent kinase CDK-1 (CDC2), -2 and -5 inhibitor. Apoptosis inducer. Antitumor agent. Inhibits cell cycle progression at the G1/S and G2/M transitions. Shown to...
| Anwendung: | Cell permeable CDK-1, -2, -5 inhibitor, Apoptosis inducer |
| CAS | 87414-49-1 |
| MW: | 424.5 D |
ab 100,00 €
PHA-793887
Artikelnummer: Cay18388-5
PHA-793887 is an inhibitor of cyclin-dependent kinases (CDKs, IC50s = 8, 8, 5, and 10 nM for Cdk2/cyclin A, Cdk2/cyclin E, Cdk5/p25, and Cdk7/cyclin H, respectively). It is selective for these CDKs over Cdk1/cyclin B, Cdk4/cyclin D1, Cdk9/cyclin T1, and glycogen synthase kinase 3beta (GSK3beta, IC50s = 60, 62, 138,...
| Schlagworte: | 3-methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c]pyrazol-3-yl]-butanamide |
| Anwendung: | CDK2, CDK5, CDK7 inhibitor |
| CAS | 718630-59-2 |
| MW: | 361.5 D |
ab 62,00 €
Cdk1/5 Inhibitor
Artikelnummer: Cay18740-1
Cyclin-dependent kinases (Cdks) are key regulators of cell cycle progression and are therefore promising targets for cancer therapy. Cdk1/5 Inhibitor is a pyrazolo [3,4-b] quioxaline that inhibits Cdk1/cyclin B and Cdk5/p25 (IC50s = 600 and 400 nM, respectively). It less potently inhibits GSK3beta (IC50 = 1 µM) and...
| Schlagworte: | Cyclin-dependent kinase 1/5 Inhibitor, NSC 693868, 1H-pyrazolo[3,4-b]quinoxalin-3-amine |
| Anwendung: | Cdk1/cyclin B inhibitor, Cdk5/p25 inhibitor |
| CAS | 40254-90-8 |
| MW: | 185.2 D |
ab 66,00 €
Roscovitine
Artikelnummer: LKT-R5774.1
Roscovitine is an inhibitor of CDKs (1, 2, 5, 7, 9, 12) and L-type Ca2+ channels, it exhibits anti-inflammatory and anticancer activities. Roscovitine resolves neutrophil-driven inflammation. In B-cell lymphoma cells, roscovitine induces cell cycle arrest and apoptosis and inhibits proliferation.
| Schlagworte: | Seliciclib, CYC202 |
| Anwendung: | CDK inhibitor |
| CAS | 186692-46-6 |
| MW: | 354.45 D |
ab 156,00 €
Hymenidin
Artikelnummer: AG-CN2-0503-M001
Amorphous solid. Soluble in DMSO, ethanol or methanol. Inhibitor of CDK5/p25 (IC50=4µ,M) and GSK-3beta (IC50=12µ,M). Potentially useful in neuronal diseases research, Antagonist of serotonergic receptors, Shown to reduce voltage-dependent calcium elevation, Moderate anticancer compound. Inhibits cell...
| Schlagworte: | N-[(2E)-3-(2-Amino-1H-imidazol-5-yl)prop-2-en-1-yl]-4-bromo-1H-pyrrole-2-carboxamide, Hymenidine, 2-Debromooroidin |
| Anwendung: | CDK5 inhibitor |
| CAS | 107019-95-4 |
| MW: | 328,2 D |
198,00 €
Anti-CDK5
Artikelnummer: ARG55212.100
Protein function: Proline-directed serine/threonine-protein kinase essential for neuronal cell cycle arrest and differentiation and may be involved in apoptotic cell death in neuronal diseases by triggering abortive cell cycle re-entry. Interacts with D1 and D3- type G1 cyclins. Phosphorylates SRC, NOS3,...
| Schlagworte: | Anti-CDK5, Anti-CDKN5, EC=2.7.11.1, Anti-TPKII catalytic subunit, Anti-Cyclin-dependent-like kinase 5, Anti-Cell division... |
| Anwendung: | FC, ICC, IF, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
584,00 €