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Anti-Recombinant APAF1, clone A709
Anti-Recombinant APAF1, clone A709

Artikelnummer: E-AN301989L.100

Apoptotic protease activating factor 1 (Apaf-1), originally identified as the mammalian homolog of the C. elegans apoptotic regulatory protein CED-4, is an important signaling protein involved in the activation of caspase-9 during apoptosis. Cytosolic Apaf-1 forms a complex with caspase-9 in the presence of...
Schlagworte: Anti-APAF1, Anti-Apoptotic protease-activating factor 1, Recombinant APAF1 Monoclonal Antibody
Anwendung: WB, IHC
Wirt: Rabbit
Spezies-Reaktivität: human, rat, mouse
ab 304,00 €
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Anti-Apaf-1 (human), clone 2E12
Anti-Apaf-1 (human), clone 2E12

Artikelnummer: AG-20T-0132-C100

Apaf-1 is a cytoplasmic protein that forms one of the central hubs in the apoptosis regulatory network. It contains (from the N terminal) a caspase recruitment domain (CARD), an ATPase domain (NB-ARC), few short helical domains and then several copies of the WD40 repeat domain. Upon binding cytochrome c and dATP,...
Schlagworte: Anti-APAF1, Anti-APAF-1, Anti-KIAA0413, Anti-Apoptotic protease-activating factor 1
Anwendung: ELISA, ICC, IHC, IP, WB
Wirt: Rat
Spezies-Reaktivität: human
341,00 €
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Anti-Apaf-1 (mouse/rat), clone 13F11
Anti-Apaf-1 (mouse/rat), clone 13F11

Artikelnummer: AG-20T-0133-C100

Apaf-1 is a cytoplasmic protein that forms one of the central hubs in the apoptosis regulatory network. It contains (from the N terminal) a caspase recruitment domain (CARD), an ATPase domain (NB-ARC), few short helical domains and then several copies of the WD40 repeat domain. Upon binding cytochrome c and dATP,...
Schlagworte: Anti-Apaf1, Anti-APAF-1, Anti-Apoptotic protease-activating factor 1
Anwendung: ELISA, ICC, IP, WB
Wirt: Rat
Spezies-Reaktivität: mouse, rat
341,00 €
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Anti-Apaf-1, clone 18H2
Anti-Apaf-1, clone 18H2

Artikelnummer: AG-20T-0134-C100

Apaf-1 is a cytoplasmic protein that forms one of the central hubs in the apoptosis regulatory network. It contains (from the N terminal) a caspase recruitment domain (CARD), an ATPase domain (NB-ARC), few short helical domains and then several copies of the WD40 repeat domain. Upon binding cytochrome c and dATP,...
Schlagworte: Anti-Apaf1, Anti-APAF-1, Anti-Apoptotic protease-activating factor 1
Anwendung: ELISA, ICC, IP, WB
Wirt: Rat
Spezies-Reaktivität: human, mouse
341,00 €
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Anti-APAF1
Anti-APAF1

Artikelnummer: ARG54332.50

Protein function: Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis. [The UniProt Consortium]
Schlagworte: Anti-APAF1, Anti-APAF-1, Anti-KIAA0413, Anti-Apoptotic protease-activating factor 1
Anwendung: WB, IHC
Wirt: Rabbit
Spezies-Reaktivität: human
641,00 €
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APAF1, human recombinant protein, N-terminal His-tag and FLAG-tag
APAF1, human recombinant protein, N-terminal His-tag and...

Artikelnummer: BPS-80116

Human apoptotic peptidase activating factor 1 (APAF1), also known as CED4, (GenBank Accession No. NM_013229), amino acids 2-1237(end) with N-terminal His-tag and N-terminal FLAG-tag, MW = 143 kDa, expressed in a baculovirus infected Sf9 cell expression system.
Schlagworte: APAF-1, KIAA0413, Apoptotic protease-activating factor 1,
Anwendung: Enzyme kinetics, inhibitor screening, selectivity profiling
Exprimiert in: Insect cells
Ursprungsart: human
MW: 143 kD
693,00 €
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Human APAF1 ELISA Kit
Human APAF1 ELISA Kit

Artikelnummer: G-HUFI02225.96

Anwendung: ELISA
Spezies-Reaktivität: human
698,00 €
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Mouse APAF1 ELISA Kit
Mouse APAF1 ELISA Kit

Artikelnummer: G-MOFI00643.96

Anwendung: ELISA
Spezies-Reaktivität: mouse
698,00 €
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Anti-Apaf-1, clone [5E11]
Anti-Apaf-1, clone [5E11]

Artikelnummer: 200-301-Y28

Anti-Apaf-1 Monoclonal Antibody was Protein A purified from monospecific antiserum by immunoaffinity purification. Cross reactivity with Apaf-1 [5E11] from other sources has not been determined. Protein function: Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9...
Schlagworte: Anti-APAF1, Anti-APAF-1, Anti-KIAA0413, Anti-Apoptotic protease-activating factor 1
Anwendung: ELISA, IHC
Wirt: Mouse
Spezies-Reaktivität: human, mouse, rat
992,00 €
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Anti-Apaf1
Anti-Apaf1

Artikelnummer: 600-401-Y26

Anti-Apaf1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with Apaf1 from other sources has not been determined. Protein function: Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the...
Schlagworte: Anti-APAF1, Anti-APAF-1, Anti-KIAA0413, Anti-Apoptotic protease-activating factor 1
Anwendung: ELISA, IHC, IFM, WB
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
848,00 €
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Apoptosis Activator 2
Apoptosis Activator 2

Artikelnummer: LKT-A6058.1

Apoptosis inducing agent.
Schlagworte: AA-2, Apoptosis activator II, AA-II
Anwendung: Apoptosis inducing agent
CAS 79183-19-0
MW: 306.14 D
ab 104,00 €
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Apoptosis Activator 2
Apoptosis Activator 2

Artikelnummer: Cay10004176-10

Apoptosis activator 2 promotes the cytochrome c-dependent oligomerization of Apaf-1 into the mature apoptosome, thus increasing procaspase-9 processing and subsequent caspase-3 activation. This compound has been shown to induce apoptosis in leukemia cells (IC50 = 4-9 µM) with weak or no effect on normal cell lines...
Schlagworte: AAII, N-(3,4-dichlorobenzyl) Isatin, 1-[(3,4-dichlorophenyl)methyl]-1H-indole-2,3-dione
Anwendung: Cell-permeable caspase activator, Apaf-1 oligomerization
CAS 79183-19-0
MW: 306.1 D
ab 57,00 €
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