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Zu "K02084" wurden 59 Artikel gefunden!
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Artikelnummer: E-AN301989L.100
Apoptotic protease activating factor 1 (Apaf-1), originally identified as the mammalian homolog of the C. elegans apoptotic regulatory protein CED-4, is an important signaling protein involved in the activation of caspase-9 during apoptosis. Cytosolic Apaf-1 forms a complex with caspase-9 in the presence of...
| Schlagworte: | Anti-APAF1, Anti-Apoptotic protease-activating factor 1, Recombinant APAF1 Monoclonal Antibody |
| Anwendung: | WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat, mouse |
ab 304,00 €
Artikelnummer: AG-20T-0132-C100
Apaf-1 is a cytoplasmic protein that forms one of the central hubs in the apoptosis regulatory network. It contains (from the N terminal) a caspase recruitment domain (CARD), an ATPase domain (NB-ARC), few short helical domains and then several copies of the WD40 repeat domain. Upon binding cytochrome c and dATP,...
| Schlagworte: | Anti-APAF1, Anti-APAF-1, Anti-KIAA0413, Anti-Apoptotic protease-activating factor 1 |
| Anwendung: | ELISA, ICC, IHC, IP, WB |
| Wirt: | Rat |
| Spezies-Reaktivität: | human |
341,00 €
Artikelnummer: AG-20T-0133-C100
Apaf-1 is a cytoplasmic protein that forms one of the central hubs in the apoptosis regulatory network. It contains (from the N terminal) a caspase recruitment domain (CARD), an ATPase domain (NB-ARC), few short helical domains and then several copies of the WD40 repeat domain. Upon binding cytochrome c and dATP,...
| Schlagworte: | Anti-Apaf1, Anti-APAF-1, Anti-Apoptotic protease-activating factor 1 |
| Anwendung: | ELISA, ICC, IP, WB |
| Wirt: | Rat |
| Spezies-Reaktivität: | mouse, rat |
341,00 €
Artikelnummer: AG-20T-0134-C100
Apaf-1 is a cytoplasmic protein that forms one of the central hubs in the apoptosis regulatory network. It contains (from the N terminal) a caspase recruitment domain (CARD), an ATPase domain (NB-ARC), few short helical domains and then several copies of the WD40 repeat domain. Upon binding cytochrome c and dATP,...
| Schlagworte: | Anti-Apaf1, Anti-APAF-1, Anti-Apoptotic protease-activating factor 1 |
| Anwendung: | ELISA, ICC, IP, WB |
| Wirt: | Rat |
| Spezies-Reaktivität: | human, mouse |
341,00 €
Artikelnummer: ARG54332.50
Protein function: Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis. [The UniProt Consortium]
| Schlagworte: | Anti-APAF1, Anti-APAF-1, Anti-KIAA0413, Anti-Apoptotic protease-activating factor 1 |
| Anwendung: | WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
641,00 €
Artikelnummer: BPS-80116
Human apoptotic peptidase activating factor 1 (APAF1), also known as CED4, (GenBank Accession No. NM_013229), amino acids 2-1237(end) with N-terminal His-tag and N-terminal FLAG-tag, MW = 143 kDa, expressed in a baculovirus infected Sf9 cell expression system.
| Schlagworte: | APAF-1, KIAA0413, Apoptotic protease-activating factor 1, |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Exprimiert in: | Insect cells |
| Ursprungsart: | human |
| MW: | 143 kD |
693,00 €
Artikelnummer: G-HUFI02225.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
698,00 €
Artikelnummer: G-MOFI00643.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
698,00 €
Artikelnummer: 200-301-Y28
Anti-Apaf-1 Monoclonal Antibody was Protein A purified from monospecific antiserum by immunoaffinity purification. Cross reactivity with Apaf-1 [5E11] from other sources has not been determined. Protein function: Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9...
| Schlagworte: | Anti-APAF1, Anti-APAF-1, Anti-KIAA0413, Anti-Apoptotic protease-activating factor 1 |
| Anwendung: | ELISA, IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, mouse, rat |
992,00 €
Artikelnummer: 600-401-Y26
Anti-Apaf1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with Apaf1 from other sources has not been determined. Protein function: Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the...
| Schlagworte: | Anti-APAF1, Anti-APAF-1, Anti-KIAA0413, Anti-Apoptotic protease-activating factor 1 |
| Anwendung: | ELISA, IHC, IFM, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
848,00 €
Artikelnummer: LKT-A6058.1
Apoptosis inducing agent.
| Schlagworte: | AA-2, Apoptosis activator II, AA-II |
| Anwendung: | Apoptosis inducing agent |
| CAS | 79183-19-0 |
| MW: | 306.14 D |
ab 104,00 €
Artikelnummer: Cay10004176-10
Apoptosis activator 2 promotes the cytochrome c-dependent oligomerization of Apaf-1 into the mature apoptosome, thus increasing procaspase-9 processing and subsequent caspase-3 activation. This compound has been shown to induce apoptosis in leukemia cells (IC50 = 4-9 µM) with weak or no effect on normal cell lines...
| Schlagworte: | AAII, N-(3,4-dichlorobenzyl) Isatin, 1-[(3,4-dichlorophenyl)methyl]-1H-indole-2,3-dione |
| Anwendung: | Cell-permeable caspase activator, Apaf-1 oligomerization |
| CAS | 79183-19-0 |
| MW: | 306.1 D |
ab 57,00 €