Zu "K01980" wurden 33 Artikel gefunden!
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Erythromycin
Artikelnummer: Cay16486-5
Erythromycin is a macrolide antibiotic that inhibits bacterial protein synthesis by targeting the 50S ribosomal subunit, blocking the progression of nascent polypeptide chains. It is active against a host of bacterial genera, including Streptococcus, Staphylococcus, and Haemophilus (MIC90s = 0.015-2.0 mg/l)....
| Schlagworte: | NSC 55929, erythromycin |
| Anwendung: | Antibacterial macrolide antibiotic, Protein synthesis inhibitor (23S rRNA of 50S ribosomal subunit) |
| CAS | 114-07-8 |
| MW: | 733.9 D |
ab 60,00 €
Rifampicin
Artikelnummer: Cay14423-100
Rifampicin is a rifamycin antibiotic and inhibitor of bacterial RNA polymerase (IC50 = 0.01 µg/ml for the E. coli enzyme). It inhibits the growth of M. tuberculosis H37Rv in mouse peritoneal macrophages (MIC = 0.8 µg/ml) as well as clinical isolates of various species of Staphylococcus, Streptococcus, Haemophilus,...
| Schlagworte: | NIH 10782, NSC 113926, Rifampin, 3-[[(4-methyl-1-piperazinyl)imino]methyl]-rifamycin |
| Anwendung: | Antibacterial Agent |
| CAS | 13292-46-1 |
| MW: | 823 D |
ab 43,00 €
Clindamycin
Artikelnummer: Cay15006-25
Clindamycin is a lincosamide antibiotic. It is active against Gram-positive bacteria, including various strains of S. pneumoniae, S. viridans, S. aureus, and S. epidermidis (MICs = 0.002-0.1, 0.005-0.2, 0.04-1.6, and 0.1-0.2 µg/ml, respectively). Clindamycin is also active against chloroquine-resistant and...
| Schlagworte: | U 21251, methyl... |
| Anwendung: | Antibacterial Agent |
| CAS | 18323-44-9 |
| MW: | 425 D |
ab 92,00 €
Clarithromycin
Artikelnummer: Cay19455-500
Clarithromycin is a polyketide synthase-derived semisynthetic macrolide antibiotic. It is active against methicillin-susceptible, but not methicillin-resistant, S. aureus (MIC50s = 0.06 and >128 µg/ml), S. pyogenes, L. monocytogenes, and B. pertussis (MIC50 = 0.015, 0.25, and =0.008 µg/ml, respectively), among...
| Schlagworte: | A-56268, Antibiotic A 56268, TE 031, 6-O-methyl-erythromycin |
| Anwendung: | Macrolide antibiotic, 50S ribosomal subunit protein synthesis inhibitor |
| CAS | 81103-11-9 |
| MW: | 748 D |
ab 66,00 €
Oleandomycin
Artikelnummer: Cay16552-5
Oleandomycin is a classic macrolide antibiotic produced by strains of Streptomyces that demonstrates antimicrobial activity similar to penicillin and erythromycin. Structurally, it consists of a macrocyclic lactone ring of 14 carbon atoms with one sugar, oleandrose, and one amino sugar, desoxamine, attached to the...
| Schlagworte: | 4-Methylumbelliferyl alpha-D-galactoside, 7-(alpha-D-galactopyranosyloxy)-4-methyl-2H-1-benzopyran-2-one |
| Anwendung: | Macrolide antibiotic, 23S rRNA of 50S ribosomal subunit / protein synthesis inhibitor |
| CAS | 3922-90-5 |
| MW: | 687.9 D |
ab 163,00 €
Linezolid
Artikelnummer: Cay15012-10
Linezolid is a synthetic oxazolidinone antibiotic with activity against a wide range of Gram-positive bacteria, including resistant strains of several species, such as methicillin-resistant S. aureus (MRSA), penicillin-resistant pneumococci, vancomycin-resistant enterococci, various anaerobic bacteria, and several...
| Schlagworte: | PNU 100766, N-[[(5S)-3-[3-fluoro-4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]-acetamide |
| Anwendung: | Antibacterial agent |
| CAS | 165800-03-3 |
| MW: | 337.4 D |
ab 109,00 €
Florfenicol
Artikelnummer: Cay19458-500
Florfenicol is a broad-spectrum fluorinated antibiotic and a derivative of thiamphenicol (Cay-21357). It is active against human clinical isolates of enteric bacteria, including E. coli, Klebsiella, Enterobacter, Citrobacter, P. mirabilis, and Salmonella (MIC50s = 6.3-12.5 µg/ml). Florfenicol is also active against...
| Schlagworte: | SCH 25298, 2,2-dichloro-N-[(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl]-acetamide |
| Anwendung: | Veterinary antibiotic, 50S ribosomal subunit protein synthesis inhibitor |
| CAS | 73231-34-2 |
| MW: | 358.2 D |
ab 50,00 €
Pleuromutilin
Artikelnummer: Cay19452-5
Pleuromutilin is an antibiotic derived from the fungus Clitopilus that inhibits bacterial protein synthesis by binding to bacterial ribosomes in the peptidyl transferase component of the 50S subunit and inhibiting peptide bond formation.Formal Name: 2-hydroxy-acetic acid,...
| Schlagworte: | Antibiotic A 40104C, Drosophilin B, NSC 121145, 2-hydroxy-acetic acid,... |
| Anwendung: | Antibiotic, Bacterial protein synthesis inhibitor |
| CAS | 125-65-5 |
| MW: | 378.5 D |
ab 125,00 €
Josamycin
Artikelnummer: CDX-J0001-GG25
White to off-white powder. Soluble in water. A member of the leucomycin family of macrolide antibiotics produced by Streptomyces kitasatoensis. May overcome anticancer drug resistance by inhibiting the binding of vinblastine or cyclosporin A to P-glycoprotein (Pgp). An antimicrobial against a wide variety of pathogens.
| Anwendung: | Macrolide antibiotic |
| CAS | 16846-24-5 |
| MW: | 827,99 D |
ab 58,00 €
Tilmicosin (phosphate)
Artikelnummer: Cay18190-10
Tilmicosin is a macrolide antibiotic. It is active against macrolide-susceptible strains of M. haemolytica, P. multocida, and E. coli (MICs = 4, 4, and 128 µM, respectively), as well as a hyperpermeable strain of E. coli (MIC = 2 µM), and inhibits bacterial protein synthesis (IC50 = 0.36 µM). Tilmicosin (75 mg/kg)...
| Schlagworte: | LY177370, Micotil,... |
| Anwendung: | 23S rRNA of 50S ribosomal subunit, protein synthesis inhibitor, Macrolide antibiotic |
| CAS | 137330-13-3 |
| MW: | 967.1 D |
ab 66,00 €
Roxithromycin
Artikelnummer: Cay19465-1
Roxithromycin is a macrolide antibiotic. It is active against various Gram-positive and Gram-negative bacteria, including five strains each of Staphylococcus and Streptococcus (geometric mean MICs = 0.08 and 0.79 µg/ml, respectively), as well as several strains each of Corynebacterium, Haemophilus, and S. pneumoniae...
| Schlagworte: | RU 28965, RU 965, 9E-[O-[(2-methoxyethoxy)methyl]oxime]-erythromycin |
| Anwendung: | Antibiotic, 50S ribosomal subunit, protein synthesis inhibitor |
| CAS | 80214-83-1 |
| MW: | 837.1 D |
ab 44,00 €
Tiamulin (fumarate)
Artikelnummer: Cay21216-100
Tiamulin is a pleuromutilin antibiotic. It is active against M. gallisepticum, M. synoviae, M. iowae, M. hyopneumoniae, M. hyosynoviae, M. hyorhinis, M. bovis, and M. agalactiae (MICs = 0.0025-0.25 µg/ml). Tiamulin is also active against various Gram-positive bacteria, including methicillin-resistant S. aureus...
| Schlagworte: | 81723 Hfu, SQ 22,947, 2-[[2-(diethylamino)ethyl]thio]-acetic acid,... |
| Anwendung: | Pleuromutilin antibiotic, peptidyl transferase inhibitor |
| CAS | 55297-96-6 |
| MW: | 609.8 D |
ab 48,00 €